Articles

Original Research

Published on 19 Dec 2025

Association between disseminated cancer and postoperative 30-day mortality in adult patients with brain tumor craniotomy

in Neuro-Oncology and Neurosurgical Oncology

Yufei Liu
Ke Cao
Rui He
Wenjian Zheng
Zongyang Li
Xuanchen Li
Mengqi Wang
Haofei Hu
Guodong Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1555850

180 views

Original Research

Published on 19 Dec 2025

Self-evolving cognitive substrates through metabolic data processing and recursive self-representation with autonomous memory prioritization mechanisms

in Machine Learning and Artificial Intelligence

Mohammadreza Nehzati

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1689727

438 views

Original Research

Published on 19 Dec 2025

Multilocus inherited neoplasia allele syndrome (MINAS) in a Turkish cohort: molecular insights and clinical relevance for precision oncology

in Pharmacology of Anti-Cancer Drugs

Taha Bahsi
Serhat Seyhan
Kaan Helvaci
Umut Demirci
Irem Bilgetekin
Selami Bayram
Mehmet Akif Ozturk
Fatih Aydogan
Serkan Keskin
Kezban Pilanci

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672774

610 views

Original Research

Published on 19 Dec 2025

Satellite-based monitoring of forage quality in grasslands of the United Kingdom using sentinel-2 data and random forest regression

in Animal Behavior and Welfare

J. G. N. Irisarri
M. A. Texeira
P. Harris
K. G. Pembleton

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1678123

372 views

Original Research

Published on 19 Dec 2025

Early genetic events in the colorectal carcinogenic pathway of familial adenomatous polyposis and sporadic polyp: germline and somatic alterations in carcinogenesis

in Cancer Genetics and Oncogenomics

Hiroki Tanabe
Yusuke Mizukami
Yusuke Ono
Hidehiro Takei
Nobue Tamamura
Yu Kobayashi
Keitaro Takahashi
Katsuyoshi Ando
Nobuhiro Ueno
Shin Kashima

Frontiers in Genetics

doi 10.3389/fgene.2025.1668133

450 views

Review

Published on 19 Dec 2025

Inflammasomes as the molecular hub of cardiovascular-metabolic-immune comorbidity networks

in Inflammation

Xingyu Qian
Jian Sun
Fei Li
Li Xu
Xingjian Hu
Nianguo Dong
Guangzhou Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690443

217 views

Original Research

Published on 19 Dec 2025

Rethinking local welfare: a network analysis of an Italian case study

in Urban Sociology

Silvia Carbone

Frontiers in Sociology

doi 10.3389/fsoc.2025.1690488

256 views

Review

Published on 19 Dec 2025

Plant bioactive compounds: extraction, biological activities, immunological, nutritional aspects, food application, and human health benefits—A comprehensive review

in Nutrition and Food Science Technology

Mohamed T. El-Saadony
Ahmed M. Saad
Dina Mostafa Mohammed
Samar Sami Alkafaas
Taia A. Abd El-Mageed
Mohamed A. Fahmy
Ahmed Ezzat Ahmed
Uthman Balgith Algopishi
Abdelghafar Mohamed Abu-Elsaoud
Walid F. A. Mosa

Frontiers in Nutrition

doi 10.3389/fnut.2025.1659743

1,807 views

Original Research

Published on 19 Dec 2025

Percutaneous left atrial appendage closure with concomitant dual-device implantation: a single-center observational study

in Structural Interventional Cardiology

Antanas Gasys
Roberto Galea
Tommaso Bini
Juan Perich-Krsnik
Marco Gamardella
Laurent Roten
George C. M. Siontis
Bernhard Meier
Lorenz Räber

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1692521

355 views

Original Research

Published on 19 Dec 2025

In-host co-colonization and bloodstream infection by distinct classical and hypervirulent CRKP clones harboring a homologous blaKPC-2-harboring plasmid

in Antibiotic Resistance and New Antimicrobial drugs

Haixing Fang
Yueliang Chen
Ying Chen
Yan Qi
Rushuang Yan
Feng Guo

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1683743

241 views

Mini Review

Published on 19 Dec 2025

Viral reprogramming of glial metabolism as a driver of neuroinflammation

in Inflammation

Tamara Rodrigues
Gabriel Salles Beltrão
Heloísa Girardi
Aguinaldo R. Pinto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686774

864 views

Original Research

Published on 19 Dec 2025

Placental serotonergic system dysregulation is associated with early impairments in infant neurodevelopment

in Reproduction

Arturo A. Canul-Euan
Arturo Flores-Pliego
Juan M. Solis-Paredes
Aurora Espejel-Nuñez
Sandra B. Parra-Hernández
Tahiri Mendoza-Hernández
María del Carmen Hernandez-Chavez
Gabriela Gil-Martínez
Carmen J. Zamora-Sánchez
Otilia Perichart-Perera

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1694018

263 views

Opinion

Published on 19 Dec 2025

Leveraging AI-based digital systems in psychological interventions: a research opinion

in Digital Mental Health

Haryasena Panduwiyasa

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1693504

673 views

Original Research

Published on 19 Dec 2025

Lymph food to improve canine atopic dermatitis: a randomized, double-blinded, controlled trial in dogs with standard-care treatment

in Animal Nutrition and Metabolism

Carolina Frizzo-Ramos
Pavlos G. Doulidis
Iwan Anton Burgener
Christa Horvath Ungerböck
Veronika Einspieler
Ulrike Weiser
Lucia Panakova
Franziska Roth-Walter

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1657869

413 views

Clinical Trial

Published on 19 Dec 2025

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

in Ethnopharmacology

Andrés Mojoli
Osvaldo Haider
Yasmin Fakih
Maria Victoria Luz Gonçalves
Bruno Zepeda Rojas
Giovanna Xaia
Emanuelly Krefta
Maíra Assunção Bicca
Thiago Lopes de Mari
Charles Francisco Ferreira

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657065

344 views

Original Research

Published on 19 Dec 2025

Body site-specific micro- and lactobiota in genitourinary infections during pregnancy

in Extra-intestinal Microbiome

Siiri Kõljalg
Epp Sepp
Jelena Štšepetova
Eva-Liina Süüden
Tiia Reimand
Madis Jaagura
Andres Salumets
Reet Mändar

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1657715

499 views

Case Report

Published on 19 Dec 2025

Case Report: Navigating novel therapies and systemic barriers in ovarian clear cell carcinoma through a complete response to lenvatinib, pembrolizumab, and SFRT

in Radiation Oncology

Jared Hobson
Allison E. Garda
Jonathan Ticku
Abigail Stockham

Frontiers in Oncology

doi 10.3389/fonc.2025.1679554

273 views

Policy Brief

Published on 19 Dec 2025

Sustainable alliance strategies in maritime delimitation for small island developing states in Africa: balancing the equitable principles and marine resource governance

in International Studies

Chuanxiang Sun

Frontiers in Political Science

doi 10.3389/fpos.2025.1670678

182 views

Original Research

Published on 19 Dec 2025

Preoperative predictors of unplanned conversion in laparoscopic liver resection: a multicenter cohort analysis

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Yin Jiang
Dipesh Kumar Yadav
Gaoqing Wang
Zhekang Jiang
Shiwei Zhang
Gong Cheng
Xinhua Zhou
Haibiao Wang
Hong Li
Yiren Hu

Frontiers in Oncology

doi 10.3389/fonc.2025.1678775

241 views

Review

Published on 19 Dec 2025

Precision bacterial immunotherapy: an integrated mechanistic taxonomy and translational roadmap against antimicrobial resistance

in Microbial Immunology

Hamdi Al-Azzani
Djandan Tadum Arthur Vithran
Hanane Aliouat
Wenhu Zhou
Xiaoqiang Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675682

297 views

Original Research

Published on 19 Dec 2025

Hepatotoxicity associated with anti-neoplastic agents: a pharmacovigilance analysis of the Food and Drug Administration Adverse Event Reporting System database

in Cancer Immunity and Immunotherapy

Lei Shi
Yan Wang
Ying Qu
Rong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665425

225 views

Original Research

Published on 19 Dec 2025

The impact of dose rate optimisation and robust optimisation on FLASH proton therapy treatment plan quality and dose rates

in Radiation Oncology

Nathalie Lövgren
Rasmus Nilsson
Erik Traneus
Kristoffer Petersson

Frontiers in Oncology

doi 10.3389/fonc.2025.1638319

363 views

Original Research

Published on 19 Dec 2025

Zoos as educational and conservation spaces: perspectives from (future) teachers

in Teacher Education

Raya Lyzanne Wolf
Paul Wilhelm Dierkes
Matthias Winfried Kleespies

Frontiers in Education

doi 10.3389/feduc.2025.1680014

230 views

Review

Published on 19 Dec 2025

The DDR-immune fitness score: a biomarker for guiding parp and immunotherapy synergy in extensive-stage small cell lung cancer

in Cancer Molecular Targets and Therapeutics

Yinxu Zhang
Xiaoyang Chen
Dai Wang
Xuan Zhou
Yuxi Wang
Guangyu Zhang
Xiaomei Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1680921

138 views

649,488 articles

Association between disseminated cancer and postoperative 30-day mortality in adult patients with brain tumor craniotomy

Self-evolving cognitive substrates through metabolic data processing and recursive self-representation with autonomous memory prioritization mechanisms

Multilocus inherited neoplasia allele syndrome (MINAS) in a Turkish cohort: molecular insights and clinical relevance for precision oncology

Satellite-based monitoring of forage quality in grasslands of the United Kingdom using sentinel-2 data and random forest regression

Early genetic events in the colorectal carcinogenic pathway of familial adenomatous polyposis and sporadic polyp: germline and somatic alterations in carcinogenesis

Inflammasomes as the molecular hub of cardiovascular-metabolic-immune comorbidity networks

Rethinking local welfare: a network analysis of an Italian case study

Plant bioactive compounds: extraction, biological activities, immunological, nutritional aspects, food application, and human health benefits—A comprehensive review

Percutaneous left atrial appendage closure with concomitant dual-device implantation: a single-center observational study

In-host co-colonization and bloodstream infection by distinct classical and hypervirulent CRKP clones harboring a homologous blaKPC-2-harboring plasmid

Viral reprogramming of glial metabolism as a driver of neuroinflammation

Placental serotonergic system dysregulation is associated with early impairments in infant neurodevelopment

Leveraging AI-based digital systems in psychological interventions: a research opinion

Lymph food to improve canine atopic dermatitis: a randomized, double-blinded, controlled trial in dogs with standard-care treatment

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

Body site-specific micro- and lactobiota in genitourinary infections during pregnancy

Case Report: Navigating novel therapies and systemic barriers in ovarian clear cell carcinoma through a complete response to lenvatinib, pembrolizumab, and SFRT

Sustainable alliance strategies in maritime delimitation for small island developing states in Africa: balancing the equitable principles and marine resource governance

Preoperative predictors of unplanned conversion in laparoscopic liver resection: a multicenter cohort analysis

Precision bacterial immunotherapy: an integrated mechanistic taxonomy and translational roadmap against antimicrobial resistance

Hepatotoxicity associated with anti-neoplastic agents: a pharmacovigilance analysis of the Food and Drug Administration Adverse Event Reporting System database

The impact of dose rate optimisation and robust optimisation on FLASH proton therapy treatment plan quality and dose rates

Zoos as educational and conservation spaces: perspectives from (future) teachers

The DDR-immune fitness score: a biomarker for guiding parp and immunotherapy synergy in extensive-stage small cell lung cancer