Frontiers in Aging Neuroscience

Original Research

Published on 24 Sep 2025

Latent profiles and correlates factors of cognitive function in older adults: a cross-sectional study

in Neurocognitive Aging and Behavior

Jin Xiang
Yan Xiong
Heting Liang
Qingyun Mao
Yumeng Zhang
Yunting Li
Zhixia Jiang
Xiaoli Yuan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1622804

2,317 views

Original Research

Published on 23 Sep 2025

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

in Neuroinflammation and Neuropathy

Debo Yun
Yongzhen Luo
Rui Li
Wenyong Li
Chunyou Wan
Qinjiang Huang
Jiang Du
Shiyi Zeng
Guangdong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627353

2,207 views

Original Research

Published on 23 Sep 2025

Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls

in Neurocognitive Aging and Behavior

Alberto Gómez-Carballa
Laura Navarro
Nour El Zahraa Mallah
Xabier Bello
Sara Pischedda
Sandra Viz-Lasheras
María José Currás
Isabel Ferreirós-Vidal
Narmeen Mallah
Julián Montoto-Louzao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1622816

2,683 views
2 citations

Original Research

Published on 23 Sep 2025

Development and validation of a prognostic scoring system for cognitive decline in adults aged 50 and older in China

in Neurocognitive Aging and Behavior

Ningjie Zhang
Linglei Meng
Zhendong Qian
Ying Jin
Hua Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1664943

2,158 views

Original Research

Published on 23 Sep 2025

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Anton A. Smolentsev
Darya V. Telegina
Nataliya G. Kolosova
Yuri P. Tsentalovich
Olga A. Snytnikova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1648561

2,413 views

Original Research

Published on 22 Sep 2025

Regional CSF volume quantification using deep learning for comparative analysis of brain atrophy in frontotemporal dementia subtypes

in Alzheimer's Disease and Related Dementias

Kyoung Yoon Lim
Soyeon Yoon
Seongbeom Park
Seongmi Kim
Kyoungmin Kim
Jehyun Ahn
Jun Pyo Kim
Hee Jin Kim
Duk L. Na
Sang Won Seo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1631640

2,161 views

Review

Published on 19 Sep 2025

STING-mediated neuroinflammation: a therapeutic target in neurodegenerative diseases

in Cellular and Molecular Mechanisms of Brain-aging

Haoqin Zhang
Ziyang He
Can Yin
Shiyi Yang
Jianqiao Li
Hong Lin
Guishan Hu
Anguo Wu
Dalian Qin
Guangqiang Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1659216

4,848 views
1 citation

Systematic Review

Published on 19 Sep 2025

Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic review and meta-analysis of 6655 participants

in Parkinson’s Disease and Aging-related Movement Disorders

Zhenzhen Zhao
Jiahui Sun
Youhong Liu
Miao Liu
Di Tong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1620172

3,155 views
2 citations

Brief Research Report

Published on 18 Sep 2025

Beyond traditional proxies: the contribution of leisure to cognitive reserve and dementia

in Neurocognitive Aging and Behavior

Silvia Ottaviani
Luca Tagliafico
Stefania Peruzzo
Marta Ponzano
Alessio Signori
Alessio Nencioni
Fiammetta Monacelli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600798

2,590 views

Original Research

Published on 18 Sep 2025

Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults

in Neurocognitive Aging and Behavior

Sriya Pallapothu
Roger D. Newman-Norlund
Nicholas Riccardi
Raghav Pallapothu
Pranesh Rajesh Kannan
Leonardo Bonilha
Julius Fridriksson
Chris Rorden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611847

2,787 views

Original Research

Published on 18 Sep 2025

Global burden of Alzheimer’s disease and other dementias (1990–2021): inequality, frontier, and decomposition analysis

in Alzheimer's Disease and Related Dementias

Haishou Fu
Huaqing Huang
Shuzhen Liao
Zhisen Dai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637029

3,677 views

Review

Published on 18 Sep 2025

Understanding Parkinson’s disease: current trends and its multifaceted complications

in Parkinson’s Disease and Aging-related Movement Disorders

Sameer A. Chaudhary
Sapana Chaudhary
Sakshi Rawat

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617106

7,500 views
1 citation

Systematic Review

Published on 17 Sep 2025

The effects of Nordic walking on cognitive function in older adults: a systematic review and meta-analysis

in Neurocognitive Aging and Behavior

Haobai Li
Ke Zhu
Jianyu Gan
Ziyi Wang
Zhikun Gao
Liangru Liu
Xiaojie Guo
Jianfeng Niu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666449

2,769 views

Original Research

Published on 17 Sep 2025

Moderating effect of APOE ε4 on the association of sleep disturbance and amyloid-β pathology among cognitively normal older adults

in Neurocognitive Aging and Behavior

Shufei Feng
Jianyu Que
Qianwen Wang
Kai Yuan
Le Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627774

2,659 views

Review

Published on 16 Sep 2025

Exercise-mediated cerebrovascular repair in Alzheimer's disease: from pathophysiology to therapeutic precision

in Alzheimer's Disease and Related Dementias

Ming Cai
Keren Cai
Ziqi Wei
Jing Zhou
Jiayi Shu
Weiyi Wang
Wanju Sun
Jingyun Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632365

3,262 views

Review

Published on 16 Sep 2025

Cerebral amyloid angiopathy: a narrative review

in Alzheimer's Disease and Related Dementias

Natalia Motzko Noto
Robert C. Speth
Lisa S. Robison

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632252

5,226 views
1 citation

Clinical Trial

Published on 16 Sep 2025

Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial

in Neurocognitive Aging and Behavior

Xiaoxing Lai
Hongwei Zhu
Yonghua Cai
Baoyu Chen
Yang Li
Hongdi Du
Liping Zhang
Wenwen Wang
Shuxian Li
Xiaopeng Huo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1639245

4,137 views

Review

Published on 16 Sep 2025

Functional Cognitive Disorder: diagnostic challenges, clinical features, and future directions in a misunderstood condition

in Neurocognitive Aging and Behavior

Ioannis Mavroudis
Foivos Petridis
Katerina Franekova
Malina Visternicu
Viorica Rarinca
Vasile Burlui
Alin Ciobica
Bogdan Novac
Irina Dobrin
Mihai Marian Hogas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1665510

3,653 views

Original Research

Published on 16 Sep 2025

Excessive daytime sleepiness and gait disturbances in patients with Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yibo Xie
Maoyun Zhao
Yanjie Guo
Panpan Tian
Sheng Liu
Hongxia Xing

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1626247

2,005 views

Systematic Review

Published on 16 Sep 2025

Microglia-associated research in Parkinson’s disease: a bibliometric analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Yan-Jun Chen
Ming-Rong Xie
Sheng-Qiang Zhou
Fang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657349

3,109 views

Original Research

Published on 16 Sep 2025

Free-water imaging of the nucleus basalis of Meynert in apolipoprotein E4 carriers

in Alzheimer's Disease and Related Dementias

Edward Ofori
B. Blair Braden
Kewei Chen
Yi Su
Richard J. Caselli
Eric M. Reiman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1597127

2,663 views

Original Research

Published on 16 Sep 2025

MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress

in Parkinson’s Disease and Aging-related Movement Disorders

Yan Cheng
Hongjiang Zhai
Yong Liu
Yunzhou Yang
Bo Fang
Mingxiang Song
Xiuqin Wang
Ping Zhong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611958

2,634 views

Original Research

Published on 12 Sep 2025

Abnormal resting-state EEG neural oscillations and functional connectivity in mild cognitive impairment

in Alzheimer's Disease and Related Dementias

Yi Jiang
Zhiwei Guo
Rubing Jiao
Haoru He
Ning Jiang
Jiayuan He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640966

3,509 views
2 citations

Review

Published on 11 Sep 2025

The interaction between resilience framework and neuron-astrocyte-synapse dynamics in AD

in Neurocognitive Aging and Behavior

Hongyue Ma
Haizhen Zhao
Xinhong Feng
Fengli Gao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1644532

3,236 views
1 citation

7,708 articles

articles

Latent profiles and correlates factors of cognitive function in older adults: a cross-sectional study

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls

Development and validation of a prognostic scoring system for cognitive decline in adults aged 50 and older in China

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

Regional CSF volume quantification using deep learning for comparative analysis of brain atrophy in frontotemporal dementia subtypes

STING-mediated neuroinflammation: a therapeutic target in neurodegenerative diseases

Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic review and meta-analysis of 6655 participants

Beyond traditional proxies: the contribution of leisure to cognitive reserve and dementia

Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults

Global burden of Alzheimer’s disease and other dementias (1990–2021): inequality, frontier, and decomposition analysis

Understanding Parkinson’s disease: current trends and its multifaceted complications

The effects of Nordic walking on cognitive function in older adults: a systematic review and meta-analysis

Moderating effect of APOE ε4 on the association of sleep disturbance and amyloid-β pathology among cognitively normal older adults

Exercise-mediated cerebrovascular repair in Alzheimer's disease: from pathophysiology to therapeutic precision

Cerebral amyloid angiopathy: a narrative review

Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial

Functional Cognitive Disorder: diagnostic challenges, clinical features, and future directions in a misunderstood condition

Excessive daytime sleepiness and gait disturbances in patients with Parkinson’s disease

Microglia-associated research in Parkinson’s disease: a bibliometric analysis

Free-water imaging of the nucleus basalis of Meynert in apolipoprotein E4 carriers

MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress

Abnormal resting-state EEG neural oscillations and functional connectivity in mild cognitive impairment

The interaction between resilience framework and neuron-astrocyte-synapse dynamics in AD