Frontiers in Aging Neuroscience

Original Research

Published on 30 May 2025

Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity

in Neurocognitive Aging and Behavior

Stephanie Matijevic
Lee Ryan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562660

1,664 views
1 citation

Original Research

Published on 30 May 2025

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

in Alzheimer's Disease and Related Dementias

Li Wu
Renxin Zhang
Yichao Wang
Shaoxing Dai
Naixue Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571783

3,695 views
1 citation

Original Research

Published on 30 May 2025

Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors

in Neuroinflammation and Neuropathy

Jie Huang
Xiaowei Zhang
Luyao Ding
Jiaxiang Yu
Mingshen Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611289

3,114 views
2 citations

Study Protocol

Published on 27 May 2025

Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

in Neurocognitive Aging and Behavior

Stephen M. Rao
Alexandria L. Chorba
M. J. Helppi
Alina Tuladhar
Amanda L. Penko
Sarah Holley
Brandon Nehls
Sabrina Paulino
Matthew C. Streicher
Audrey Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584115

3,562 views

Original Research

Published on 27 May 2025

Predictive model for the therapeutic effect of bilateral subthalamic nucleus deep brain stimulation on the freezing of gait in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Qi Limuge
Yuqing Zhang
Xiaofei Jia
Fang Wang
Dongsheng Yu
Lixia Chen
Li Zhang
Yongqiang Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1511845

2,361 views

Original Research

Published on 27 May 2025

Cerebral gray matter volume identifies healthy older drivers with a critical decline in driving safety performance using actual vehicles on a closed-circuit course

in Neurocognitive Aging and Behavior

Handityo Aulia Putra
Kaechang Park
Fumio Yamashita

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1462951

1,778 views
1 citation

Original Research

Published on 27 May 2025

Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Marianna Riello
Monica Moroni
Stefano Bovo
Flavio Ragni
Manuela Buganza
Raffaella Di Giacopo
Marco Chierici
Lorenzo Gios
Matteo Pardini
Federico Massa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565006

3,608 views
1 citation

Correction

Published on 26 May 2025

Corrigendum: Effects of off-line auricular transcutaneous vagus nerve stimulation (taVNS) on a short-term memory task: a pilot study

in Neurocognitive Aging and Behavior

Francesco Fisicaro
Klizia Cortese
Rita Bella
Manuela Pennisi
Giuseppe Lanza
Kaoru Yuasa
Yoshikazu Ugawa
Yasuo Terao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1626368

1,608 views
1 citation

Original Research

Published on 26 May 2025

Moderate alcohol consumption does not protect cognitive function when controlling for income and cultural factors

in Neurocognitive Aging and Behavior

Kerri M. Gillespie
Eva Kemps
Melanie J. White
Selena E. Bartlett

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569069

7,400 views

Original Research

Published on 26 May 2025

Correlation between physical activity levels and the risk of cognitive impairment in Chinese older adults

in Neurocognitive Aging and Behavior

Feng-Wei Dong
Dong-Hui Wang
Yu-Jie Chang
Li-Xu Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1519494

4,111 views

Original Research

Published on 22 May 2025

Functional connectivity in distributed cortical networks associated with semantic processing in healthy older adults

in Neurocognitive Aging and Behavior

Kailey G. Langer
Alexandria G. O’Neal
Amanda Garcia
Alexa Chen
Eric C. Porges
John B. Williamson
Adam J. Woods
Ronald A. Cohen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1479861

2,543 views

Review

Published on 21 May 2025

Exploring the landscape of Parkinson’s disease transcriptomics: a quantitative review of research progress and future directions

in Parkinson’s Disease and Aging-related Movement Disorders

Yiran Wang
Tong Li
Xiaoqing Zhang
Haoran Tai
Weihong Li
Bingyin Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505374

4,768 views
2 citations

Systematic Review

Published on 21 May 2025

Recent advances (2022–2024) in eye-tracking for Parkinson’s disease: a promising tool for diagnosing and monitoring symptoms

in Parkinson’s Disease and Aging-related Movement Disorders

Laura Culicetto
Davide Cardile
Giulia Marafioti
Viviana Lo Buono
Francesca Ferraioli
Simona Massimino
Giuseppe Di Lorenzo
Chiara Sorbera
Amelia Brigandì
Carmelo Mario Vicario

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1534073

6,017 views
8 citations

Original Research

Published on 21 May 2025

Association between osteoporosis and mortality in Parkinson's disease with mediating effect of hip fractures: a Korean nationwide population-based study

in Parkinson’s Disease and Aging-related Movement Disorders

Yeonju Jin
Bo Kyu Choi
Jong Woo Lee
Jin Yong Hong
Ickpyo Hong
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552381

2,364 views

General Commentary

Published on 21 May 2025

Commentary: Association between metallic implants and stroke in US adults from NHANES 2015–2023 a cross-sectional study

in Neuroinflammation and Neuropathy

Xiangming Li
Peixing Huang
Guizhong Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1586693

1,961 views

Original Research

Published on 21 May 2025

Genetic analysis of ERBB4 gene in Chinese patients with amyotrophic lateral sclerosis: a single-center study and systematic review of published literature

in Parkinson’s Disease and Aging-related Movement Disorders

Dongchao Shen
Xunzhe Yang
Di He
Kang Zhang
Shuangwu Liu
Xiaohan Sun
Jinyue Li
Zhengyi Cai
Mingsheng Liu
Xue Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584541

2,507 views

Review

Published on 21 May 2025

Exercise training exerts beneficial effects on Alzheimer’s disease through multiple signaling pathways

in Cellular and Molecular Mechanisms of Brain-aging

Jihe Kang
Mei Liu
Qiang Yang
Xiangji Dang
Qun Li
Ting Wang
Bin Qiu
Yibao Zhang
Xudong Guo
Xiaoling Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1558078

5,579 views
8 citations

Original Research

Published on 20 May 2025

Cerebral pulsatility might be a driver of neurofunctional reorganization in the aging brain: an MRI and NIRS study

in Neurocognitive Aging and Behavior

Hanieh Mohammadi
Parikshat Sirpal
Louis Bherer
Frédéric Lesage
Yves Joanette

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1486775

2,759 views
1 citation

General Commentary

Published on 20 May 2025

Commentary: The letter to editor regarding “Association between serum estradiol levels and cognitive function in older women: a cross-sectional analysis”

in Neurocognitive Aging and Behavior

Jiayi Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1559647

1,496 views

Correction

Published on 19 May 2025

Corrigendum: Parkin characteristics and blood biomarkers of Parkinson's disease in WPBLC study

in Parkinson’s Disease and Aging-related Movement Disorders

Haijun He
Xi Xiong
Yi Zheng
Jialong Hou
Tao Jiang
Weiwei Quan
Jiani Huang
Jiaxue Xu
Keke Chen
Jingjing Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1621994

1,378 views
1 citation

Study Protocol

Published on 19 May 2025

Differences in sensory-motor cortex activation patterns during level and stair walking in patients with knee osteoarthritis: protocol for a cross-sectional study

in Neurocognitive Aging and Behavior

Qian Deng
Guohua Jin
Xia Lou
Yuwu Ding
Haichen Xu
Kun Yang
Bingli Liu
Liming Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1589645

3,209 views

Original Research

Published on 19 May 2025

Network localization of regional homogeneity alterations in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yuanying Song
Hucheng Yang
Siyu Gu
Yingling Zhu
ZhenYu Dai
Pinglei Pan
Xianxian Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607691

2,479 views
2 citations

Original Research

Published on 19 May 2025

Association of white matter hyperintensity burden and infarct volume in the anterior choroidal artery territory with early neurological progression: a dual-center retrospective study

in Neuroinflammation and Neuropathy

Weiwei Gao
Lixue Wang
Junyi Huang
Yitao Yu
Jingjing She
Mingyang Wang
Lijuan Cai
Taishan Kang
Xingyu Chen
Jianzhong Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1577742

1,880 views

Systematic Review

Published on 19 May 2025

Research hotspots of irisin in the nervous system: a bibliometric study and visualization analysis via CiteSpace

in Neuroinflammation and Neuropathy

Jiacheng Wang
Juan Liu
Wei Pang
Xin Li
Xinping Huang
Shan Wang
Chunxiao Nan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1488559

3,552 views
2 citations

7,789 articles

articles

Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors

Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

Predictive model for the therapeutic effect of bilateral subthalamic nucleus deep brain stimulation on the freezing of gait in Parkinson’s disease

Cerebral gray matter volume identifies healthy older drivers with a critical decline in driving safety performance using actual vehicles on a closed-circuit course

Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease

Corrigendum: Effects of off-line auricular transcutaneous vagus nerve stimulation (taVNS) on a short-term memory task: a pilot study

Moderate alcohol consumption does not protect cognitive function when controlling for income and cultural factors

Correlation between physical activity levels and the risk of cognitive impairment in Chinese older adults

Functional connectivity in distributed cortical networks associated with semantic processing in healthy older adults

Exploring the landscape of Parkinson’s disease transcriptomics: a quantitative review of research progress and future directions

Recent advances (2022–2024) in eye-tracking for Parkinson’s disease: a promising tool for diagnosing and monitoring symptoms

Association between osteoporosis and mortality in Parkinson's disease with mediating effect of hip fractures: a Korean nationwide population-based study

Commentary: Association between metallic implants and stroke in US adults from NHANES 2015–2023 a cross-sectional study

Genetic analysis of ERBB4 gene in Chinese patients with amyotrophic lateral sclerosis: a single-center study and systematic review of published literature

Exercise training exerts beneficial effects on Alzheimer’s disease through multiple signaling pathways

Cerebral pulsatility might be a driver of neurofunctional reorganization in the aging brain: an MRI and NIRS study

Commentary: The letter to editor regarding “Association between serum estradiol levels and cognitive function in older women: a cross-sectional analysis”

Corrigendum: Parkin characteristics and blood biomarkers of Parkinson's disease in WPBLC study

Differences in sensory-motor cortex activation patterns during level and stair walking in patients with knee osteoarthritis: protocol for a cross-sectional study

Network localization of regional homogeneity alterations in Parkinson’s disease

Association of white matter hyperintensity burden and infarct volume in the anterior choroidal artery territory with early neurological progression: a dual-center retrospective study

Research hotspots of irisin in the nervous system: a bibliometric study and visualization analysis via CiteSpace