Frontiers in Aging Neuroscience

Review

Published on 05 Nov 2025

Brain microenvironment orchestrates highly aggressive tumor variants: current trends and therapeutic approaches

in Neuroinflammation and Neuropathy

Juhi Mishra
John D. Dickinson
Shailendra Kumar Maurya

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666837

1,410 views

Original Research

Published on 05 Nov 2025

Influence of diabetes on the efficacy of DL-3-n-butylphthalide in post-stroke cognitive impairment: a 12-month prospective cohort study

in Neurocognitive Aging and Behavior

Yuting Lu
Lifeng Wang
Juan Hao
Jingjing Song
Chenxi Fan
Xianjia Ning
Jinghua Wang
Yan Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1649248

1,340 views

Review

Published on 05 Nov 2025

Cross-generational mechanisms of maternal gut microbiota in modulating offspring autism spectrum disorder risk: from the gut-brain axis to translational challenges in precision interventions

in Neurocognitive Aging and Behavior

Dashuang Zhang
Min Zhou
Yudan Qiu
Hong Xu
Hanmin Liu
Yang Liu
Liang Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1642240

2,541 views

Original Research

Published on 03 Nov 2025

From genomic discovery to application in age-related hearing loss: a global bibliometric and cross-ethnic analysis

in Cellular and Molecular Mechanisms of Brain-aging

Yang Lu
Jiawei Shen
Ka Ho Kairos Sou
Hsi Lu
Shuoyuan Huang
Kai Uus

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1678115

1,979 views

Original Research

Published on 31 Oct 2025

Brain connectivity moderated the effects of cognitive intraindividual variability on mobility in cognitively frail older adults

in Neurocognitive Aging and Behavior

Jingyi Wu
Jinyu Chen
Juncen Wu
Wayne Lap Sun Chan
Yijian Yang
Chun Liang Hsu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1682996

1,239 views

Original Research

Published on 31 Oct 2025

Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin

in Alzheimer's Disease and Related Dementias

Deborah L. Croteau
Jose Fernandez Navarro
Thomas Comptdaer
Zaneta Andrusivova
Aleksandra Jurek
Eliette Bonnefoy
Luc Buée
Vilhelm A. Bohr
Joakim Lundeberg
Marie-Christine Galas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1656850

1,555 views

Original Research

Published on 31 Oct 2025

Prevalence, associated factors and impact of mild cognitive impairment in hospitalized older adults with Parkinson’s disease: a cross-sectional study

in Parkinson’s Disease and Aging-related Movement Disorders

Siyuan Gong
Tianqi Wang
Rongzhu Tang
Wangjuan Hu
Wenjing Wang
Jia Li
Jihong Liu
Chunlian Liao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693417

1,181 views

Mini Review

Published on 29 Oct 2025

Improving recognition and management of inpatient delirium in Parkinson’s disease: evidence review and implications for clinical care

in Parkinson’s Disease and Aging-related Movement Disorders

Colin Coleman
Adrianne Smiley
Sheera Rosenfeld
Anne Brooks

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693827

1,404 views

Original Research

Published on 29 Oct 2025

An intricate relationship: stress markers and associative memory in a laboratory experiment in older adults

in Neurocognitive Aging and Behavior

Luisa Knopf
Gregor Domes
Siri-Maria Kamp

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666566

1,016 views

Hypothesis and Theory

Accepted on 28 Oct 2025

The Interplay of Homeostasis, Inflammation, and Oxidative Stress in Neurodegenerative Disorders: The Role of Biological Markers, Antioxidants, Lithium, and TMS — A Proposed Framework for Preventing Neurodegenerative Disorders Through Biomarkers and Multimodal Therapies

in Neuroinflammation and Neuropathy

Leonard Lado, MD, ABPN, RPh
Aruna Misir, Medical Student and Researcher

Frontiers in Aging Neuroscience

644 views

Review

Published on 28 Oct 2025

Drug discovery and development for Parkinson’s disease: are preclinical models good enough?

in Parkinson’s Disease and Aging-related Movement Disorders

Alejandro Reinares-Sebastián
Noelia Esteban-García
Masahiko Takada
Inés Trigo-Damas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1692592

2,015 views

Original Research

Published on 28 Oct 2025

Directed brain connectivity biomarkers of healthy aging and Parkinson’s disease staging

in Parkinson’s Disease and Aging-related Movement Disorders

Tauqeer Anjum
Ali Seyfizadeh
Hao Ding
Tahir Mahmood
Rüdiger Pryss
Jens Volkmann
Dumitru Ciolac
Muthuraman Muthuraman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1698600

1,293 views

Original Research

Accepted on 27 Oct 2025

Association between oral frailty and cognitive impairment in older adults: a cross-sectional study

in Neurocognitive Aging and Behavior

Mingzhu Lu
Yiming Wei
Ruili Zhang
Huijuan Li
Jiahui Zhai
Xiaohan Cheng

Frontiers in Aging Neuroscience

303 views

Original Research

Published on 27 Oct 2025

Multimodal radiomics of cerebellar subregions for machine learning-driven Alzheimer’s disease diagnosis

in Alzheimer's Disease and Related Dementias

Xinqing Hao
Ying Li
Xiulin Wang
Changjun Ma
Ruichen Liu
Yang Jiao
Chunbo Dong
Jing Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1679788

1,178 views

Original Research

Published on 27 Oct 2025

Chronic kidney disease, proteinuria, and mortality risk in patients with Parkinson’s disease: a 12-year longitudinal study

in Parkinson’s Disease and Aging-related Movement Disorders

Kyoungwon Baik
Minwoong Kang
Yu Jeong Park
Su Jin Chung
Kyungmi Oh
Sung Hoon Kang
Seong-Beom Koh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1631079

1,033 views

Editorial

Published on 27 Oct 2025

Editorial: Neuroinflammation and distribution of proinflammatory markers in the brain

in Neuroinflammation and Neuropathy

Huazheng Liang
Yong Hao
Yong Bi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1723530

1,114 views

Original Research

Published on 23 Oct 2025

Peak alpha frequency as an objective biomarker for cognitive assessment in post-stroke cognitive impairment

in Neurocognitive Aging and Behavior

Yuqing Zhao
Haoran Shi
Weicheng Kong
Xinyang Wang
Wei Wei
Zengtu Zhan
Xiehua Xue

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1639970

1,548 views

Original Research

Published on 23 Oct 2025

The effects of type 2 diabetes mellitus on postural adaptation and complexity during a visual search task in older adults

in Neurocognitive Aging and Behavior

Mahdiyeh M. Manafi
Alexander Wolfe
Junhong Zhou
Wanting Yu
Ikechukwu Iloputaife
Tongjian You
Brad Manor
Azizah J. Jor’dan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1650484

1,681 views

Original Research

Published on 22 Oct 2025

Gender-related differences in cognitive performance and cognitive stimulation efficacy in subjects with Parkinson’s disease and mild cognitive impairment

in Parkinson’s Disease and Aging-related Movement Disorders

Noemi Iaccino
Jolanda Buonocore
Giusi Torchia
Francesca Curcio
Fabio M. Pirrotta
Marianna Contrada
Loris Pignolo
Antonio Gambardella
Gennarina Arabia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1672084

1,312 views

Editorial

Published on 22 Oct 2025

Editorial: Current chemical approaches in combating neuroinflammation in Alzheimer's disease (AD)

in Alzheimer's Disease and Related Dementias

Sayan Roy Chowdhury
Venkatesh Katari
Dwaipayan Sen
Prasenjit Mondal

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1712601

1,141 views

Original Research

Published on 22 Oct 2025

Diagnostic classification of mild cognitive impairment in Parkinson's disease using subject-level stratified machine-learning analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Jing Wang
Yanfang Chen
Xiao Xie
Pengwei Wang
Hang Hu
Hongfang Han
Lihan Wang
Li Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1687925

1,577 views

Original Research

Published on 22 Oct 2025

Stressors-induced cognitive dysfunction during aging: mechanisms and future challenges

in Neurocognitive Aging and Behavior

Yizhe Zhang
Xiao Zhang
Jiaxi Guo
Wanbing Dai
Sifan Chen
Lili Huang
Xuwu Xiang
Weifeng Yu
Diansan Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630982

1,402 views

Original Research

Published on 22 Oct 2025

Top motor and non-motor complaints in patients with Parkinson's disease

in Parkinson’s Disease and Aging-related Movement Disorders

José Fidel Baizabal-Carvallo
Marlene Alonso-Juarez
Robert Fekete

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1664934

1,658 views

Original Research

Published on 22 Oct 2025

Baseline CSF ferritin levels were associated with trajectories of depressive symptoms among older people without dementia

in Alzheimer's Disease and Related Dementias

Qing Wang
Xinwu Ye
Yongjian Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516388

970 views

7,708 articles

articles

Brain microenvironment orchestrates highly aggressive tumor variants: current trends and therapeutic approaches

Influence of diabetes on the efficacy of DL-3-n-butylphthalide in post-stroke cognitive impairment: a 12-month prospective cohort study

Cross-generational mechanisms of maternal gut microbiota in modulating offspring autism spectrum disorder risk: from the gut-brain axis to translational challenges in precision interventions

From genomic discovery to application in age-related hearing loss: a global bibliometric and cross-ethnic analysis

Brain connectivity moderated the effects of cognitive intraindividual variability on mobility in cognitively frail older adults

Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin

Prevalence, associated factors and impact of mild cognitive impairment in hospitalized older adults with Parkinson’s disease: a cross-sectional study

Improving recognition and management of inpatient delirium in Parkinson’s disease: evidence review and implications for clinical care

An intricate relationship: stress markers and associative memory in a laboratory experiment in older adults

The Interplay of Homeostasis, Inflammation, and Oxidative Stress in Neurodegenerative Disorders: The Role of Biological Markers, Antioxidants, Lithium, and TMS — A Proposed Framework for Preventing Neurodegenerative Disorders Through Biomarkers and Multimodal Therapies

Drug discovery and development for Parkinson’s disease: are preclinical models good enough?

Directed brain connectivity biomarkers of healthy aging and Parkinson’s disease staging

Association between oral frailty and cognitive impairment in older adults: a cross-sectional study

Multimodal radiomics of cerebellar subregions for machine learning-driven Alzheimer’s disease diagnosis

Chronic kidney disease, proteinuria, and mortality risk in patients with Parkinson’s disease: a 12-year longitudinal study

Editorial: Neuroinflammation and distribution of proinflammatory markers in the brain

Peak alpha frequency as an objective biomarker for cognitive assessment in post-stroke cognitive impairment

The effects of type 2 diabetes mellitus on postural adaptation and complexity during a visual search task in older adults

Gender-related differences in cognitive performance and cognitive stimulation efficacy in subjects with Parkinson’s disease and mild cognitive impairment

Editorial: Current chemical approaches in combating neuroinflammation in Alzheimer's disease (AD)

Diagnostic classification of mild cognitive impairment in Parkinson's disease using subject-level stratified machine-learning analysis

Stressors-induced cognitive dysfunction during aging: mechanisms and future challenges

Top motor and non-motor complaints in patients with Parkinson's disease

Baseline CSF ferritin levels were associated with trajectories of depressive symptoms among older people without dementia