Frontiers in Aging Neuroscience

Original Research

Published on 21 Oct 2025

Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Wen Peng Shan
Shi Lei Yan
Yuan Yuan Guo
Hua Ke Yang
Jing Chun Wang
Jie Xiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630003

1,510 views

Original Research

Published on 21 Oct 2025

Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study

in Neurocognitive Aging and Behavior

Marcos Maldonado-Díaz
Gonzalo Jara-Vargas
Felipe González-Seguel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671477

2,169 views

Review

Published on 21 Oct 2025

Levodopa-induced dyskinesia in Parkinson’s disease: an updated review of pharmacological treatments

in Parkinson’s Disease and Aging-related Movement Disorders

Feifei Chen
Changqing Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1684885

2,803 views

Original Research

Published on 20 Oct 2025

Translational insights into pain mechanisms and balance impairments in aging: a cross-sectional study

in Neurocognitive Aging and Behavior

Mastour Saeed Alshahrani
Ravi Shankar Reddy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1656854

1,111 views

Systematic Review

Published on 20 Oct 2025

Oscillatory dynamics of motor learning across adulthood life span: a systematic review

in Neurocognitive Aging and Behavior

Amir Jahanian-Najafabadi
Elaheh Davoodi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1646172

1,823 views

Original Research

Published on 20 Oct 2025

Peripheral immunity patterns, imaging features, and clinical outcomes in patients with gait impairment and ventriculomegaly on brain MRI

in Parkinson’s Disease and Aging-related Movement Disorders

Christian Espinoza-Vinces
Iciar Aviles-Olmos
Jorge M. Núñez-Córdoba
Marcos Jiménez-Vázquez
Marta Calvo-Imirizaldu
Genoveva Montoya-Murillo
Gloria Martí-Andrés
Javier Arbizu
María-Rosario Luquin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1685288

1,300 views

Original Research

Accepted on 17 Oct 2025

Leveraging Object Detection for Early Diagnosis of Neurodegenerative Diseases through Radiomic Analysis

in Neurocognitive Aging and Behavior

Linjian Huang
Miaoran Li
Xin Xu
Zhijian Xie

Frontiers in Aging Neuroscience

451 views

Original Research

Published on 17 Oct 2025

Elevated gonadotropins and risk of dementia in Chinese adults aged over 80: a cross-sectional study

in Alzheimer's Disease and Related Dementias

Yunxia Zhu
Youyi Tu
Chenxi Ren
Yingying Ke
Qihao Guo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1651723

1,065 views

Brief Research Report

Published on 17 Oct 2025

Elucidating the role of APOE ε4 gene variants in the clinical manifestation of Parkinson's disease

in Parkinson’s Disease and Aging-related Movement Disorders

Gita Vita Soraya
Yusran Ady Fitrah
Andi Kurnia Bintang
Muhammad Akbar
Alfi Raudatil Jannah
Zulvikar Syambani Ulhaq
Jumraini Tammasse
Cahyono Kaelan
Muhammad Nasrum Massi
Ai Obinata

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632480

1,671 views

Original Research

Published on 16 Oct 2025

Characterizing sleep-related phenotypes with patient-reported outcomes in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Sandeep Grover
Celina Chand
Mollie McKenzie Acuff
Joshua Farahnik
Laurie K. Mischley

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630150

1,913 views

Original Research

Published on 16 Oct 2025

LOU/c/jall rat as a model of resilience in the context of streptozotocin-induced cognitive impairment

in Alzheimer's Disease and Related Dementias

Lucas Gephine
Sophie Corvaisier
Benoît Bernay
Thomas Freret
Marianne Leger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666397

1,378 views

Original Research

Published on 16 Oct 2025

Mediating role of brain aging in the effect of white matter hyperintensities on post-stroke aphasia severity

in Neurocognitive Aging and Behavior

Guihua Xu
Yongsheng Wu
Rui Zhu
Junyu Qu
Wenwen Xu
Jiaxiang Xin
Dawei Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1629870

1,119 views

Original Research

Published on 16 Oct 2025

Differential effects of physical activity on behavioral and prefrontal responses during repetitive inhibitory control in older adults

in Neurocognitive Aging and Behavior

Jae-Hoon Lee
Minchul Lee
Min-Seong Ha

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1684331

1,190 views

Systematic Review

Published on 15 Oct 2025

Effectiveness and safety of acupuncture for Parkinson’s disease anxiety: a systematic review and meta-analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Lu Chen
Hong-xiao Xu
Zhao-qin Wang
Guo-na Li
Lu-yi Wu
Yan Huang
Huan-gan Wu
Jian-hua Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1663059

2,020 views

Systematic Review

Published on 15 Oct 2025

Association between periodontal disease and Alzheimer's disease: a scoping review

in Alzheimer's Disease and Related Dementias

Xiaocui Zhang
Xin Huang
Mengdie Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588008

3,253 views

Original Research

Published on 14 Oct 2025

Quantitative analysis of gait and balance using deep learning on monocular videos and the timed up and go test in idiopathic normal-pressure hydrocephalus

in Parkinson’s Disease and Aging-related Movement Disorders

Hee-Jin Cho
Sangwook Kim
Hosang Yu
Sungmoon Jeong
Kyunghun Kang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1644543

1,830 views

Review

Published on 13 Oct 2025

Copper homeostasis and cuproptosis: implications for neurodegenerative diseases

in Cellular and Molecular Mechanisms of Brain-aging

Feng Tao
Mengxuan Lin
Xiang Meng
Linghui Huang
Bifang Zhuo
Siyi Jiang
Shizhe Deng
Zhihong Meng
Jiangwei Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1688554

3,146 views

Review

Published on 10 Oct 2025

Metabolic Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Federica Invernizzi
Lorenzo Ciocca
Elena Contaldi
Donato Inverso
Daniela Calandrella
Francesco Mignone
Michela Barichella
Ioannis Ugo Isaias
Gianni Pezzoli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1665957

3,357 views

Original Research

Published on 10 Oct 2025

Deciphering Alzheimer’s disease transcriptomics: exploration and validation of core genes in tau and Aβ pathological models toward novel therapeutic targets

in Alzheimer's Disease and Related Dementias

Hui E. Zhang
Meng Li Xiao
Jin Jin Ji
Yu Rong Cheng
Fang Lu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1621153

2,188 views

Original Research

Published on 10 Oct 2025

Clinical validation of a plasma-based antibody-free LC–MS method for identifying CSF amyloid positivity in mild cognitive impairment

in Alzheimer's Disease and Related Dementias

José Antonio Allué
Leticia Sarasa
Noelia Fandos
Ricardo Gonzalo
Rubén Sabido-Vera
Jorge Loscos
Judith Romero
Adrián Sánchez
Jose Terencio
Jordi A. Matias-Guiu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1681516

1,798 views

Original Research

Published on 10 Oct 2025

Attention-based Transformer-LSTM architecture for early diagnosis and staging of early-stage Parkinson’s disease using fNIRS data

in Parkinson’s Disease and Aging-related Movement Disorders

Huan Wang
Hujun Wang
Shuyan Qie
Congxiao Wang
Nan Li
Hanming Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1677722

1,806 views

Original Research

Published on 10 Oct 2025

Asrij/OCIAD1 contributes to age-associated microglial activation and neuroinflammation in mice

in Cellular and Molecular Mechanisms of Brain-aging

Prathamesh Dongre
Madhu Ramesh
Thimmaiah Govindaraju
Maneesha S. Inamdar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1674136

2,102 views

Review

Published on 09 Oct 2025

Parkinson’s disease beyond the brain: implications for treatments

in Parkinson’s Disease and Aging-related Movement Disorders

Setareh Malekian Naeini
Marc Danzell Lopez
Paul E. Fraser
Anurag Tandon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600782

1,929 views

Original Research

Published on 09 Oct 2025

Impairment of human spatial orientation in the horizontal, but not the vertical plane, due to aging, cognitive decline, or chronic peripheral vestibular loss

in Neurocognitive Aging and Behavior

Johannes Gerb
Vivien Oertle
Burak Onmus
Marianne Dieterich
Thomas Brandt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671562

1,408 views
1 citation

7,708 articles

articles

Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson’s disease

Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study

Levodopa-induced dyskinesia in Parkinson’s disease: an updated review of pharmacological treatments

Translational insights into pain mechanisms and balance impairments in aging: a cross-sectional study

Oscillatory dynamics of motor learning across adulthood life span: a systematic review

Peripheral immunity patterns, imaging features, and clinical outcomes in patients with gait impairment and ventriculomegaly on brain MRI

Leveraging Object Detection for Early Diagnosis of Neurodegenerative Diseases through Radiomic Analysis

Elevated gonadotropins and risk of dementia in Chinese adults aged over 80: a cross-sectional study

Elucidating the role of APOE ε4 gene variants in the clinical manifestation of Parkinson's disease

Characterizing sleep-related phenotypes with patient-reported outcomes in Parkinson’s disease

LOU/c/jall rat as a model of resilience in the context of streptozotocin-induced cognitive impairment

Mediating role of brain aging in the effect of white matter hyperintensities on post-stroke aphasia severity

Differential effects of physical activity on behavioral and prefrontal responses during repetitive inhibitory control in older adults

Effectiveness and safety of acupuncture for Parkinson’s disease anxiety: a systematic review and meta-analysis

Association between periodontal disease and Alzheimer's disease: a scoping review

Quantitative analysis of gait and balance using deep learning on monocular videos and the timed up and go test in idiopathic normal-pressure hydrocephalus

Copper homeostasis and cuproptosis: implications for neurodegenerative diseases

Metabolic Parkinson’s disease

Deciphering Alzheimer’s disease transcriptomics: exploration and validation of core genes in tau and Aβ pathological models toward novel therapeutic targets

Clinical validation of a plasma-based antibody-free LC–MS method for identifying CSF amyloid positivity in mild cognitive impairment

Attention-based Transformer-LSTM architecture for early diagnosis and staging of early-stage Parkinson’s disease using fNIRS data

Asrij/OCIAD1 contributes to age-associated microglial activation and neuroinflammation in mice

Parkinson’s disease beyond the brain: implications for treatments

Impairment of human spatial orientation in the horizontal, but not the vertical plane, due to aging, cognitive decline, or chronic peripheral vestibular loss