Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 16 Sep 2024

Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke

in Alzheimer's Disease and Related Dementias

Jae-Sung Lim
Jae-Joong Lee
Geon Ha Kim
Hang-Rai Kim
Dong Woo Shin
Keon-Joo Lee
Min Jae Baek
Eunvin Ko
Beom Joon Kim
SangYun Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1430408

3,368 views

Original Research

Published on 13 Sep 2024

EBF1 is a potential biomarker for predicting progression from mild cognitive impairment to Alzheimer's disease: an in silico study

in Alzheimer's Disease and Related Dementias

Yanxiu Ju
Songtao Li
Xiangyi Kong
Qing Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1397696

2,683 views
1 citation

Original Research

Published on 13 Sep 2024

Effects of obesogenic diet and 17β-estradiol in female mice with APOE 3/3, 3/4, and 4/4 genotypes

in Alzheimer's Disease and Related Dementias

Amy Christensen
Cassandra J. McGill
Wenjie Qian
Christian J. Pike

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1415072

3,238 views
4 citations

Original Research

Published on 12 Sep 2024

Association of white matter hyperintensities with cognitive decline and neurodegeneration

in Alzheimer's Disease and Related Dementias

Tao-Ran Li
Bai-Le Li
Xin-Ran Xu
Jin Zhong
Tai-Shan Wang
Feng-Qi Liu
the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1412735

5,594 views
13 citations

Original Research

Published on 11 Sep 2024

Association between blood pressure and dementia in older adults: a cross-sectional study from China

in Alzheimer's Disease and Related Dementias

Tingting Yi
Zhou Su
Jiyang Wang
Jinghuan Gan
Hao Wu
Zhihong Shi
Zhen Sun
Shuai Liu
Yong Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1466089

2,537 views
1 citation

Perspective

Published on 04 Sep 2024

In 2024, the amyloid-cascade-hypothesis still remains a working hypothesis, no less but certainly no more

in Alzheimer's Disease and Related Dementias

Christian Behl

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1459224

10,643 views
20 citations

Original Research

Published on 04 Sep 2024

Genome-wide association analysis and admixture mapping in a Puerto Rican cohort supports an Alzheimer disease risk locus on chromosome 12

in Alzheimer's Disease and Related Dementias

Bilcag Akgun
Briseida E. Feliciano-Astacio
Kara L. Hamilton-Nelson
Kyle Scott
Joe Rivero
Larry D. Adams
Jose J. Sanchez
Glenies S. Valladares
Sergio Tejada
Parker L. Bussies

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1459796

3,510 views
4 citations

Review

Published on 03 Sep 2024

Automated brain segmentation and volumetry in dementia diagnostics: a narrative review with emphasis on FreeSurfer

in Alzheimer's Disease and Related Dementias

Eya Khadhraoui
Thomas Nickl-Jockschat
Hans Henkes
Daniel Behme
Sebastian Johannes Müller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1459652

5,921 views
8 citations

Original Research

Published on 02 Sep 2024

Impact of multiple infections on risk of incident dementia according to subjective cognitive decline status: a nationwide population-based cohort study

in Alzheimer's Disease and Related Dementias

Jung-Won Lee
Mina Kim
Hoseob Kim
Sunghwan Kim
Yoo Hyun Um
Sheng-Min Wang
Hyun Kook Lim
Chang Uk Lee
Dong Woo Kang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1410185

3,149 views
1 citation

Mini Review

Published on 29 Aug 2024

Development of capillary dysfunction in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

S. Vorobev
S. Yanishevskiy
S. Efimtsev
A. Sokolov
V. Dyachuk

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1458455

3,003 views
1 citation

Original Research

Published on 29 Aug 2024

Alteration in temporal-cerebellar effective connectivity can effectively distinguish stable and progressive mild cognitive impairment

in Alzheimer's Disease and Related Dementias

Chen Xue
Darui Zheng
Yiming Ruan
Wenxuan Guo
Jun Hu
for the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1442721

2,347 views
4 citations

Original Research

Published on 27 Aug 2024

Identification of cross-talk pathways and PANoptosis-related genes in periodontitis and Alzheimer’s disease by bioinformatics analysis and machine learning

in Alzheimer's Disease and Related Dementias

Xiantao Chen
Yifei Dai
Yushen Li
Jiajun Xin
Jiatong Zou
Rui Wang
Hao Zhang
Zhihui Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1430290

5,945 views
3 citations

Systematic Review

Published on 21 Aug 2024

The impact of physical exercise on neuroinflammation mechanism in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Junhui Hu
Baiqing Huang
Kang Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1444716

9,717 views
20 citations

Systematic Review

Published on 15 Aug 2024

The relationship between hippocampal changes in healthy aging and Alzheimer’s disease: a systematic literature review

in Alzheimer's Disease and Related Dementias

Michael Woodward
David A. Bennett
Tatjana Rundek
George Perry
Tomasz Rudka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1390574

6,554 views
11 citations

Original Research

Published on 14 Aug 2024

Deep learning-based quantification of brain atrophy using 2D T1-weighted MRI for Alzheimer’s disease classification

in Alzheimer's Disease and Related Dementias

Chae Jung Park
Yu Hyun Park
Kichang Kwak
Soohwan Choi
Hee Jin Kim
Duk L. Na
Sang Won Seo
Min Young Chun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423515

7,587 views
2 citations

Original Research

Published on 12 Aug 2024

Characterizing the clinical heterogeneity of early symptomatic Alzheimer’s disease: a data-driven machine learning approach

in Alzheimer's Disease and Related Dementias

Xiwu Wang
Teng Ye
Deguo Jiang
Wenjun Zhou
Jie Zhang
for the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1410544

3,448 views
2 citations

Original Research

Published on 09 Aug 2024

Modeling APOE ε4 familial Alzheimer’s disease in directly converted 3D brain organoids

in Alzheimer's Disease and Related Dementias

Yunkyung Kim
Hongwon Kim
Byounggook Cho
Saemin An
Soi Kang
Sumin Kim
Jongpil Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1435445

4,438 views
7 citations

Review

Published on 09 Aug 2024

Alzheimer’s disease: a review on the current trends of the effective diagnosis and therapeutics

in Alzheimer's Disease and Related Dementias

Aimi Syamima Abdul Manap
Reema Almadodi
Shirin Sultana
Maheishinii Grace Sebastian
Kenil Sureshbhai Kavani
Vanessa Elle Lyenouq
Aravind Shankar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1429211

20,849 views
29 citations

Original Research

Published on 08 Aug 2024

O-GlcNAc impacts mitophagy via the PINK1-dependent pathway

in Alzheimer's Disease and Related Dementias

Ibtihal M. Alghusen
Marisa S. Carman
Heather M. Wilkins
Taylor A. Strope
Caleb Gimore
Halyna Fedosyuk
Jad Shawa
Sophiya John Ephrame
Aspin R. Denson
Xiaowan Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1387931

7,716 views
11 citations

Systematic Review

Published on 08 Aug 2024

Gut microbiota changes in patients with Alzheimer’s disease spectrum based on 16S rRNA sequencing: a systematic review and meta-analysis

in Alzheimer's Disease and Related Dementias

Hui Li
Xiaopan Cui
Yuxiu Lin
Fengqiong Huang
Ayong Tian
Rongwei Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1422350

7,713 views
22 citations

Original Research

Published on 07 Aug 2024

The involvement of effector memory CD4+ T cells in mediating the impact of genus Oscillibacter gut microbiota on Alzheimer’s disease: a Mendelian randomization study

in Alzheimer's Disease and Related Dementias

Huachang Zhang
Yudong Wang
Hui Zhao
Wei Wang
Fabin Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423707

3,568 views
3 citations

Original Research

Published on 07 Aug 2024

Association of peak expiratory flow with motoric cognitive risk syndrome among older adults

in Alzheimer's Disease and Related Dementias

Hui Xu
Xiangwen Gong
Kaiwang Cui
Xuerui Li
Long Chen
Yiyi Lu
Yangfang Liao
Jianping Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1412542

4,864 views
3 citations

Original Research

Published on 06 Aug 2024

The association between rs6859 in NECTIN2 gene and Alzheimer’s disease is partly mediated by pTau

in Alzheimer's Disease and Related Dementias

Aravind Lathika Rajendrakumar
Konstantin G. Arbeev
Olivia Bagley
Anatoliy I. Yashin
Svetlana Ukraintseva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1388363

2,876 views
5 citations

Original Research

Published on 02 Aug 2024

Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1–42) profoundly and progressively alters brain function throughout life

in Alzheimer's Disease and Related Dementias

Marco Kramer
Thu-Huong Hoang
Honghong Yang
Olena Shchyglo
Juliane Böge
Ute Neubacher
Jens Colitti-Klausnitzer
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1397901

2,791 views
2 citations

2,205 articles

articles

Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke

EBF1 is a potential biomarker for predicting progression from mild cognitive impairment to Alzheimer's disease: an in silico study

Effects of obesogenic diet and 17β-estradiol in female mice with APOE 3/3, 3/4, and 4/4 genotypes

Association of white matter hyperintensities with cognitive decline and neurodegeneration

Association between blood pressure and dementia in older adults: a cross-sectional study from China

In 2024, the amyloid-cascade-hypothesis still remains a working hypothesis, no less but certainly no more

Genome-wide association analysis and admixture mapping in a Puerto Rican cohort supports an Alzheimer disease risk locus on chromosome 12

Automated brain segmentation and volumetry in dementia diagnostics: a narrative review with emphasis on FreeSurfer

Impact of multiple infections on risk of incident dementia according to subjective cognitive decline status: a nationwide population-based cohort study

Development of capillary dysfunction in Alzheimer’s disease

Alteration in temporal-cerebellar effective connectivity can effectively distinguish stable and progressive mild cognitive impairment

Identification of cross-talk pathways and PANoptosis-related genes in periodontitis and Alzheimer’s disease by bioinformatics analysis and machine learning

The impact of physical exercise on neuroinflammation mechanism in Alzheimer’s disease

The relationship between hippocampal changes in healthy aging and Alzheimer’s disease: a systematic literature review

Deep learning-based quantification of brain atrophy using 2D T1-weighted MRI for Alzheimer’s disease classification

Characterizing the clinical heterogeneity of early symptomatic Alzheimer’s disease: a data-driven machine learning approach

Modeling APOE ε4 familial Alzheimer’s disease in directly converted 3D brain organoids

Alzheimer’s disease: a review on the current trends of the effective diagnosis and therapeutics

O-GlcNAc impacts mitophagy via the PINK1-dependent pathway

Gut microbiota changes in patients with Alzheimer’s disease spectrum based on 16S rRNA sequencing: a systematic review and meta-analysis

The involvement of effector memory CD4+ T cells in mediating the impact of genus Oscillibacter gut microbiota on Alzheimer’s disease: a Mendelian randomization study

Association of peak expiratory flow with motoric cognitive risk syndrome among older adults

The association between rs6859 in NECTIN2 gene and Alzheimer’s disease is partly mediated by pTau

Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1–42) profoundly and progressively alters brain function throughout life