Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 02 Aug 2024

Senescence-related genes and proteins in the development of Alzheimer’s disease: evidence from transcriptomic and Mendelian randomization analysis

in Alzheimer's Disease and Related Dementias

Ying Liu
Jiao Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423725

4,728 views

Original Research

Published on 24 Jul 2024

Association of liver function markers and apolipoprotein E ε4 with pathogenesis and cognitive decline in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Sang-Won Han
Sang-Hwa Lee
Jong Ho Kim
Jae-Jun Lee
Young Ho Park
SangYun Kim
Kwangsik Nho
Jong-Hee Sohn

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1411466

3,820 views
3 citations

Original Research

Published on 23 Jul 2024

Correlation of brain tissue volume loss with inflammatory biomarkers IL1β, P-tau, T-tau, and NLPR3 in the aging cognitively impaired population

in Alzheimer's Disease and Related Dementias

Kyung Mi Lee
Sang Tae Kim
Yunan Tian
Sue Min Jung
Yunjung Chang
Hak Young Rhee
Soonchan Park
Chang-Woo Ryu
Woo-In Lee
Eui Jong Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1388654

2,884 views
1 citation

Review

Published on 22 Jul 2024

Cognitive dysfunction in animal models of human lewy-body dementia

in Alzheimer's Disease and Related Dementias

Caroline Haikal
Graham M. Winston
Michael G. Kaplitt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1369733

4,362 views
4 citations

Review

Published on 17 Jul 2024

The relationship between hypoxia and Alzheimer’s disease: an updated review

in Alzheimer's Disease and Related Dementias

Borui Tao
Wei Gong
Chengyuan Xu
Zhihui Ma
Jinyu Mei
Ming Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1402774

6,209 views
17 citations

Original Research

Published on 17 Jul 2024

Identification of deregulated lncRNAs in Alzheimer’s disease: an integrated gene co-expression network analysis of hippocampus and fusiform gyrus RNA-seq datasets

in Alzheimer's Disease and Related Dementias

Ermes Filomena
Ernesto Picardi
Apollonia Tullo
Graziano Pesole
Anna Maria D’Erchia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1437278

3,570 views
2 citations

Original Research

Published on 16 Jul 2024

Association of modified dementia risk score with cerebrospinal fluid biomarkers and cognition in adults without dementia

in Alzheimer's Disease and Related Dementias

Qiong-Yao Li
Yan Fu
Xin-Jing Cui
Zuo-Teng Wang
Lan Tan
for the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1339163

3,056 views
1 citation

Original Research

Published on 15 Jul 2024

The role of Immune cells in Alzheimer's disease: a bidirectional Mendelian randomization study

in Alzheimer's Disease and Related Dementias

Erdong Zhang
Tingting Chen
Yanqin Chen
Chenxiang Long
Ling Tao
Xiangchun Shen
Fengqiu Dai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1433691

4,633 views
3 citations

Systematic Review

Published on 15 Jul 2024

Bibliometric analysis of neuroinflammation and Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Wenxian Sun
Jin Gong
Shaoqi Li
Pin Wang
Xiaodong Han
Chang Xu
Heya Luan
Ruina Li
Boye Wen
Cuibai Wei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423139

6,018 views
6 citations

Original Research

Published on 10 Jul 2024

Quantifying neuroinflammation within deep gray matter in small vessel disease using diffusion tensor based free-water imaging: a longitudinal study

in Alzheimer's Disease and Related Dementias

Yawen Sun
Xu Han
Zhenghao Li
Yage Qiu
Ying Hu
Yuyao Zhang
Yongming Dai
Hongjiang Wei
Qun Xu
Yan Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1361436

2,850 views
3 citations

Original Research

Published on 09 Jul 2024

Associations of endogenous estrogens, plasma Alzheimer’s disease biomarkers, and APOE4 carrier status on regional brain volumes in postmenopausal women

in Alzheimer's Disease and Related Dementias

Katrina A. Wugalter
Rachel A. Schroeder
Rebecca C. Thurston
Minjie Wu
Howard J. Aizenstein
Ann D. Cohen
M. Ilyas Kamboh
Thomas K. Karikari
Carol A. Derby
Pauline M. Maki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1426070

4,070 views
2 citations

Original Research

Published on 08 Jul 2024

Toward the development of a sporadic model of Alzheimer's disease: comparing pathologies between humanized APP and the familial J20 mouse models

in Alzheimer's Disease and Related Dementias

Peggy Rentsch
Kiruthika Ganesan
Alexander Langdon
Lyndsey M. Konen
Bryce Vissel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1421900

3,104 views
1 citation

Original Research

Published on 05 Jul 2024

Occlusion dysfunction and Alzheimer’s disease: Mendelian randomization study

in Alzheimer's Disease and Related Dementias

Qing Wang
Wenyu Zhen
Rui Hu
Zifei Wang
Yuqiang Sun
Wansu Sun
Chunxia Huang
Jianguang Xu
Hengguo Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423322

3,546 views
4 citations

Original Research

Published on 04 Jul 2024

ACOT7, a candidate and novel serum biomarker of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Jintao Wang
Yong Feng
Yingni Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1345668

4,274 views
1 citation

Mini Review

Published on 03 Jul 2024

The emerging role of brain neuroinflammatory responses in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Mandana Amelimojarad
Melika Amelimojarad
Xiaonan Cui

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1391517

5,375 views
20 citations

Original Research

Published on 03 Jul 2024

Time trends in Alzheimer’s disease mortality attributable to metabolic risks and smoking in China from 1990 to 2019: an age-period-cohort analysis

in Alzheimer's Disease and Related Dementias

Simeng Sun
Ting Zhang
Hao Yu
Ting Xia
Yunan Yao
Mengting Sun
Hongmei Liang
Qiaoyu Huang
Weiwei Wang
Huafeng Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1425577

6,561 views
12 citations

Original Research

Published on 28 Jun 2024

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

in Alzheimer's Disease and Related Dementias

Allen L. Pan
Mickael Audrain
Emmy Sakakibara
Rajeev Joshi
Xiaodong Zhu
Qian Wang
Minghui Wang
Noam D. Beckmann
Eric E. Schadt
Sam Gandy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1400447

4,089 views
7 citations

Original Research

Published on 26 Jun 2024

Integration of single-cell sequencing with machine learning and Mendelian randomization analysis identifies the NAP1L1 gene as a predictive biomarker for Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Runming Chen
Yujun Xie
Ze Chang
Wenyue Hu
Zhenyun Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1406160

5,811 views
3 citations

Original Research

Published on 26 Jun 2024

Predicting Alzheimer's disease CSF core biomarkers: a multimodal Machine Learning approach

in Alzheimer's Disease and Related Dementias

Anna Michela Gaeta
María Quijada-López
Ferran Barbé
Rafaela Vaca
Montse Pujol
Olga Minguez
Manuel Sánchez-de-la-Torre
Arrate Muñoz-Barrutia
Gerard Piñol-Ripoll

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1369545

6,668 views
12 citations

Original Research

Published on 21 Jun 2024

Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age

in Alzheimer's Disease and Related Dementias

Melih Tarhan
Tim Hartl
Olena Shchyglo
Jens Colitti-Klausnitzer
Angela Kuhla
Tobias Maximilian Breuer
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1373477

2,688 views

Original Research

Published on 21 Jun 2024

Enhancing predictive validity of motoric cognitive risk syndrome for incident dementia and all-cause mortality with handgrip strength: insights from a prospective cohort study

in Alzheimer's Disease and Related Dementias

Weimin Bai
Ruizhu Ma
Yanhui Yang
Juan Xu
Lijie Qin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1421656

2,396 views
2 citations

Original Research

Published on 19 Jun 2024

In-vivo neuronal dysfunction by Aβ and tau overlaps with brain-wide inflammatory mechanisms in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Lazaro M. Sanchez-Rodriguez
Ahmed F. Khan
Quadri Adewale
Gleb Bezgin
Joseph Therriault
Jaime Fernandez-Arias
Stijn Servaes
Nesrine Rahmouni
Cécile Tissot
Jenna Stevenson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1383163

5,123 views
7 citations

Editorial

Published on 18 Jun 2024

Editorial: Visualization and assessment of cerebral vasculature, cerebrospinal fluids, and the brain parenchyma in dementia and aging

in Alzheimer's Disease and Related Dementias

Jianpan Huang
Yachao Zhang
Lin Chen
Dengrong Jiang
Zixuan Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1443028

2,262 views

Original Research

Published on 18 Jun 2024

Long-lasting improvements in episodic memory among subjects with mild cognitive impairment who received transcranial direct current stimulation combined with cognitive treatment and telerehabilitation: a multicentre, randomized, active-controlled study

in Alzheimer's Disease and Related Dementias

Rosa Manenti
Francesca Baglio
Ilaria Pagnoni
Elena Gobbi
Elena Campana
Cristina Alaimo
Federica Rossetto
Sonia Di Tella
Chiara Pagliari
Andrea Geviti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1414593

4,601 views
4 citations

2,205 articles

articles

Senescence-related genes and proteins in the development of Alzheimer’s disease: evidence from transcriptomic and Mendelian randomization analysis

Association of liver function markers and apolipoprotein E ε4 with pathogenesis and cognitive decline in Alzheimer’s disease

Correlation of brain tissue volume loss with inflammatory biomarkers IL1β, P-tau, T-tau, and NLPR3 in the aging cognitively impaired population

Cognitive dysfunction in animal models of human lewy-body dementia

The relationship between hypoxia and Alzheimer’s disease: an updated review

Identification of deregulated lncRNAs in Alzheimer’s disease: an integrated gene co-expression network analysis of hippocampus and fusiform gyrus RNA-seq datasets

Association of modified dementia risk score with cerebrospinal fluid biomarkers and cognition in adults without dementia

The role of Immune cells in Alzheimer's disease: a bidirectional Mendelian randomization study

Bibliometric analysis of neuroinflammation and Alzheimer’s disease

Quantifying neuroinflammation within deep gray matter in small vessel disease using diffusion tensor based free-water imaging: a longitudinal study

Associations of endogenous estrogens, plasma Alzheimer’s disease biomarkers, and APOE4 carrier status on regional brain volumes in postmenopausal women

Toward the development of a sporadic model of Alzheimer's disease: comparing pathologies between humanized APP and the familial J20 mouse models

Occlusion dysfunction and Alzheimer’s disease: Mendelian randomization study

ACOT7, a candidate and novel serum biomarker of Alzheimer’s disease

The emerging role of brain neuroinflammatory responses in Alzheimer’s disease

Time trends in Alzheimer’s disease mortality attributable to metabolic risks and smoking in China from 1990 to 2019: an age-period-cohort analysis

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

Integration of single-cell sequencing with machine learning and Mendelian randomization analysis identifies the NAP1L1 gene as a predictive biomarker for Alzheimer's disease

Predicting Alzheimer's disease CSF core biomarkers: a multimodal Machine Learning approach

Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age

Enhancing predictive validity of motoric cognitive risk syndrome for incident dementia and all-cause mortality with handgrip strength: insights from a prospective cohort study

In-vivo neuronal dysfunction by Aβ and tau overlaps with brain-wide inflammatory mechanisms in Alzheimer’s disease

Editorial: Visualization and assessment of cerebral vasculature, cerebrospinal fluids, and the brain parenchyma in dementia and aging

Long-lasting improvements in episodic memory among subjects with mild cognitive impairment who received transcranial direct current stimulation combined with cognitive treatment and telerehabilitation: a multicentre, randomized, active-controlled study