Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 19 Jun 2025

The effect of periodontal status in the associations between socioeconomic status and cognitive performance: a mediation analysis in older adults

in Alzheimer's Disease and Related Dementias

Heming Zhang
Hongxia Xiang
Lin Zhang
Zhiyang Chen
Wei Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1524268

1,081 views

Original Research

Published on 18 Jun 2025

Impact of cognitive decline on the physical functioning of older adults in Southern Brazil: a cross-sectional study

in Alzheimer's Disease and Related Dementias

Andréa Kruger Gonçalves
Valéria Feijó Martins
Ana Carolina Kanitz
Flávia Gomes Martinez
Leonardo Alexandre Peyré-Tartaruga
Raphael Machado Castilhos
Aline Nogueira Haas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549764

1,216 views

Original Research

Published on 17 Jun 2025

Brain microvascular calcification is increased in human donors with dementia compared to elderly controls: a pilot study

in Alzheimer's Disease and Related Dementias

Kelly A. Borges
Isabelle Lombardi
Mackenzie Sivilli
Joseph Aabye
Isabella Romano
Saud A. Nasruddin
Mugdha V. Padalkar
Daniel Moussouros
Olga V. Savinova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1557625

1,407 views

Original Research

Published on 17 Jun 2025

Effects of West Nile virus on behavioral and cognitive performance, cortical Aβ pathology, viral loads, and immune measures of middle-aged NL-G-F/E3 and NL-G-F/E4 mice

in Alzheimer's Disease and Related Dementias

Abigail O’Niel
Christopher J. Parkins
Alexandra Pederson
Elizabeth Saltonstall
Emily Bunnell
Ria Aggarwal
Phoebe Sandholm
Kat Kessler
Henry F. Harrison
Jessica L. Smith

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600119

1,489 views

Original Research

Accepted on 16 Jun 2025

Quantitative Analysis of Targeted Lipidomics in The Hippocampus of APP/PS1 Mice Employing UHPLC-MS/MS Method

in Alzheimer's Disease and Related Dementias

Shiyu Xiao
Xuemeng Wei
Bing Han
Xiaoqian Shi
Congzhen Wei
Rumeng Liang
Jingna Sun
Zheng Zhang
Zhengang Han
Li Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1561831

153 views

Original Research

Accepted on 16 Jun 2025

Altered Dynamic Functional Network Connectivity Patterns in Alzheimer's Disease: Insights into Neural Dysfunction

in Alzheimer's Disease and Related Dementias

Xuerui Pang
Yi Ji
Chenyang Hu
Yulong Dai
Panpan Hu
Xingqi Wu
Kai Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617191

153 views

Original Research

Accepted on 16 Jun 2025

Cerebellar MRI-Based Radiomics Models for Identifying Mild Cognitive Impairment：A Retrospectively Multicenter Study in Southeast of China

in Alzheimer's Disease and Related Dementias

Jianping Lu
Guoen Cai
Naian Xiao
Kunmu Zheng
Qinyong Ye
Xiaochun Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566247

123 views

Original Research

Published on 16 Jun 2025

CITA GO-ON study. A community based multidomain lifestyle intervention to prevent cognitive decline. Protocol design and recruitment process

in Alzheimer's Disease and Related Dementias

Mikel Tainta
Mirian Ecay-Torres
Myriam Barandiaran
Ainara Estanga
Carolina López
Miren Altuna
Ane Iriondo
Jon Saldias
Maite Garcia-Sebastian
Marta Cañada

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539711

1,687 views

Original Research

Published on 16 Jun 2025

A high-accuracy, low-cost blood test for Alzheimer’s disease: validating P-tau181/Aβ42 in real-world cohorts

in Alzheimer's Disease and Related Dementias

Dequan Liu
Hang Li
Qing Liu
Haiyan Li
Yuanyuan Tang
Kaiting Cheng
Tong Li
Yulan Chu
Xiaodong Jia
Wenying Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1599761

1,378 views

Review

Published on 13 Jun 2025

Infections with Chlamydia pneumoniae and SARS-CoV-2 and Alzheimer’s disease pathogenesis

in Alzheimer's Disease and Related Dementias

Alexa Romanella
Maegan McCall
Rachel Corwin
Alaha Abdul Faruq
Emily Lingo
Sanya Bhambhani
Christine J. Hammond
Brian J. Balin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587782

2,227 views

Original Research

Published on 04 Jun 2025

Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS

in Alzheimer's Disease and Related Dementias

Lang Peng
Qingwei Xiang
Ge Jia
Renyi Yin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540272

1,816 views

Review

Published on 02 Jun 2025

Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia

in Alzheimer's Disease and Related Dementias

Ilinca Untu
Michael Davidson
Gabriela-Dumitrita Stanciu
Jonathan Rabinowitz
Romeo-Petru Dobrin
Diana-Sabina Vieru
Bogdan-Ionel Tamba

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584607

1,278 views

Review

Accepted on 30 May 2025

Dysregulated calcium signaling in the aged primate association cortices: Vulnerability to Alzheimer's disease neuropathology

in Alzheimer's Disease and Related Dementias

Amy F T Arnsten
Isabella Perone
Min Wang
Shengtao Yang
Stacy Uchendu
Dinar Bolat
Dibyadeep Datta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1610350

226 views

Original Research

Published on 30 May 2025

Blood essential trace elements and Alzheimer’s disease biomarkers in midlife

in Alzheimer's Disease and Related Dementias

Xin Wang
Kelly M. Bakulski
Carrie A. Karvonen-Gutierrez
Sung Kyun Park
David Morgan
Brian P. Jackson
Roger L. Albin
Henry L. Paulson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539749

898 views

Original Research

Published on 30 May 2025

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

in Alzheimer's Disease and Related Dementias

Li Wu
Renxin Zhang
Yichao Wang
Shaoxing Dai
Naixue Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571783

1,106 views

Original Research

Published on 27 May 2025

Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Marianna Riello
Monica Moroni
Stefano Bovo
Flavio Ragni
Manuela Buganza
Raffaella Di Giacopo
Marco Chierici
Lorenzo Gios
Matteo Pardini
Federico Massa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565006

1,351 views