Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 13 Nov 2025

Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms

in Alzheimer's Disease and Related Dementias

Hao Zhang
WenJun Chen
ShuYou Yuan
Bo Cai
ShaoXiang Ding
HongXia Bao
JunKai Sun
Wei Lu
HaoGang Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1597511

1,372 views

Correction

Published on 12 Nov 2025

Correction: Five-year dementia prediction and decision support system based on real-world data

in Alzheimer's Disease and Related Dementias

Themis P. Exarchos
George A. Dimakopoulos
Konstantinos Lazaros
Marios Krokidis
Aristidis Vrahatis
Gerasimos Grammenos
Antigoni Avramouli
Konstantina Skolariki
Roy Adams
Vasiliki Mahairaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1719723

878 views

Original Research

Published on 11 Nov 2025

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Andrea Riberas-Sánchez
Soleil García-Brito
Laia Vila-Solés
Laura Aldavert-Vera
Pilar Segura-Torres
Gemma Huguet
Gemma Carreras-Badosa
Elisabet Kádár

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671196

1,114 views

Review

Published on 07 Nov 2025

Exercise modulation of gut microbiota in Alzheimer’s disease: pathophysiological mechanisms and therapeutic perspectives

in Alzheimer's Disease and Related Dementias

Si-yi Leng
Qi-hang Yang
Yang Yuan
Bingao Chen
Hongbao Chen
Weikang Ban
Jiahao Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1677896

1,669 views

Review

Published on 06 Nov 2025

Biological determinants of blood-based biomarker levels in Alzheimer’s disease: role of nutrition, inflammation, and metabolic factors

in Alzheimer's Disease and Related Dementias

Aparna Inamdar
Parashuram Bugadannavar
Mahesh Palled
Savita Umarani
Preeti Salve
Bannimath Gurupadayya
Priyanka Patil
Himanshu Sharma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1614962

2,538 views

Original Research

Published on 31 Oct 2025

Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin

in Alzheimer's Disease and Related Dementias

Deborah L. Croteau
Jose Fernandez Navarro
Thomas Comptdaer
Zaneta Andrusivova
Aleksandra Jurek
Eliette Bonnefoy
Luc Buée
Vilhelm A. Bohr
Joakim Lundeberg
Marie-Christine Galas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1656850

1,553 views

Original Research

Published on 27 Oct 2025

Multimodal radiomics of cerebellar subregions for machine learning-driven Alzheimer’s disease diagnosis

in Alzheimer's Disease and Related Dementias

Xinqing Hao
Ying Li
Xiulin Wang
Changjun Ma
Ruichen Liu
Yang Jiao
Chunbo Dong
Jing Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1679788

1,169 views

Editorial

Published on 22 Oct 2025

Editorial: Current chemical approaches in combating neuroinflammation in Alzheimer's disease (AD)

in Alzheimer's Disease and Related Dementias

Sayan Roy Chowdhury
Venkatesh Katari
Dwaipayan Sen
Prasenjit Mondal

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1712601

1,138 views

Original Research

Published on 22 Oct 2025

Baseline CSF ferritin levels were associated with trajectories of depressive symptoms among older people without dementia

in Alzheimer's Disease and Related Dementias

Qing Wang
Xinwu Ye
Yongjian Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516388

968 views

Original Research

Published on 17 Oct 2025

Elevated gonadotropins and risk of dementia in Chinese adults aged over 80: a cross-sectional study

in Alzheimer's Disease and Related Dementias

Yunxia Zhu
Youyi Tu
Chenxi Ren
Yingying Ke
Qihao Guo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1651723

1,062 views

Original Research

Published on 16 Oct 2025

LOU/c/jall rat as a model of resilience in the context of streptozotocin-induced cognitive impairment

in Alzheimer's Disease and Related Dementias

Lucas Gephine
Sophie Corvaisier
Benoît Bernay
Thomas Freret
Marianne Leger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666397

1,374 views

Systematic Review

Published on 15 Oct 2025

Association between periodontal disease and Alzheimer's disease: a scoping review

in Alzheimer's Disease and Related Dementias

Xiaocui Zhang
Xin Huang
Mengdie Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588008

3,242 views

Original Research

Published on 10 Oct 2025

Deciphering Alzheimer’s disease transcriptomics: exploration and validation of core genes in tau and Aβ pathological models toward novel therapeutic targets

in Alzheimer's Disease and Related Dementias

Hui E. Zhang
Meng Li Xiao
Jin Jin Ji
Yu Rong Cheng
Fang Lu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1621153

2,182 views

Original Research

Published on 10 Oct 2025

Clinical validation of a plasma-based antibody-free LC–MS method for identifying CSF amyloid positivity in mild cognitive impairment

in Alzheimer's Disease and Related Dementias

José Antonio Allué
Leticia Sarasa
Noelia Fandos
Ricardo Gonzalo
Rubén Sabido-Vera
Jorge Loscos
Judith Romero
Adrián Sánchez
Jose Terencio
Jordi A. Matias-Guiu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1681516

1,798 views

Original Research

Published on 09 Oct 2025

Tortuous extracranial arteries contribute to white Matter hyperintensities in aging brains

in Alzheimer's Disease and Related Dementias

Zhe Sun
Chenyang Li
Arjun V. Masurkar
Marco Muccio
Thomas Wisniewski
Yulin Ge

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1641214

1,274 views

Review

Published on 07 Oct 2025

Kynurenine pathway: a possible new mechanism for exercise in the prevention and treatment of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Gangqiang Li
Shuang Li
Wenhui Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617690

2,090 views

Original Research

Published on 06 Oct 2025

The association between chronic rhinosinusitis and the risk of dementia: a longitudinal study

in Alzheimer's Disease and Related Dementias

Xinyu Zhang
Zhongmin Yin
Jia Luo
Runsheng Yang
Weijing Wang
Dongfeng Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609790

2,426 views

Original Research

Published on 02 Oct 2025

Predictive gene expression signatures for Alzheimer’s disease using post-mortem brain tissue

in Alzheimer's Disease and Related Dementias

Ashley H. Duche
Oliver Tan
Andrius Baskys
Rachita K. Sumbria
Moom R. Roosan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1591946

2,592 views
1 citation

Original Research

Published on 30 Sep 2025

Five-year dementia prediction and decision support system based on real-world data

in Alzheimer's Disease and Related Dementias

Themis P. Exarchos
George A. Dimakopoulos
Konstantinos Lazaros
Marios Krokidis
Aristidis Vrahatis
Gerasimos Grammenos
Antigoni Avramouli
Konstantina Skolariki
Roy Adams
Vasiliki Mahairaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1670609

2,831 views

Original Research

Published on 26 Sep 2025

EEG-based minimum spanning tree analysis reveals network disruptions in Alzheimer’s disease spectrum: an observational study

in Alzheimer's Disease and Related Dementias

Xing Ye
Yixin Yan
Yingying Wang
Jingping Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1604345

1,947 views

Methods

Published on 25 Sep 2025

Current application status of non-invasive brain stimulation techniques in Alzheimer’s disease: a bibliometric analysis

in Alzheimer's Disease and Related Dementias

Shan Cong
Meng Wang
Long Yan
Li Sun
Bowen Zheng
Jinying Xie
Tao Yu
Yulin Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1585885

2,796 views
1 citation

Correction

Published on 25 Sep 2025

Correction: Altered dynamic functional network connectivity patterns in Alzheimer's disease: insights into neural dysfunction

in Alzheimer's Disease and Related Dementias

Xuerui Pang
Yi Ji
Chenyang Hu
Yulong Dai
Panpan Hu
Xingqi Wu
Kai Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693649

1,197 views

Systematic Review

Published on 24 Sep 2025

Unveiling the glymphatic system’s impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012–2024)

in Alzheimer's Disease and Related Dementias

Younian Wang
Qiangsheng Liu
Junyi Wu
Kun Meng
Lanting Zhou
Fan Ye

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598608

4,050 views
2 citations

Original Research

Published on 23 Sep 2025

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Anton A. Smolentsev
Darya V. Telegina
Nataliya G. Kolosova
Yuri P. Tsentalovich
Olga A. Snytnikova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1648561

2,410 views

2,205 articles

articles

Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms

Correction: Five-year dementia prediction and decision support system based on real-world data

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer’s disease

Exercise modulation of gut microbiota in Alzheimer’s disease: pathophysiological mechanisms and therapeutic perspectives

Biological determinants of blood-based biomarker levels in Alzheimer’s disease: role of nutrition, inflammation, and metabolic factors

Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin

Multimodal radiomics of cerebellar subregions for machine learning-driven Alzheimer’s disease diagnosis

Editorial: Current chemical approaches in combating neuroinflammation in Alzheimer's disease (AD)

Baseline CSF ferritin levels were associated with trajectories of depressive symptoms among older people without dementia

Elevated gonadotropins and risk of dementia in Chinese adults aged over 80: a cross-sectional study

LOU/c/jall rat as a model of resilience in the context of streptozotocin-induced cognitive impairment

Association between periodontal disease and Alzheimer's disease: a scoping review

Deciphering Alzheimer’s disease transcriptomics: exploration and validation of core genes in tau and Aβ pathological models toward novel therapeutic targets

Clinical validation of a plasma-based antibody-free LC–MS method for identifying CSF amyloid positivity in mild cognitive impairment

Tortuous extracranial arteries contribute to white Matter hyperintensities in aging brains

Kynurenine pathway: a possible new mechanism for exercise in the prevention and treatment of Alzheimer's disease

The association between chronic rhinosinusitis and the risk of dementia: a longitudinal study

Predictive gene expression signatures for Alzheimer’s disease using post-mortem brain tissue

Five-year dementia prediction and decision support system based on real-world data

EEG-based minimum spanning tree analysis reveals network disruptions in Alzheimer’s disease spectrum: an observational study

Current application status of non-invasive brain stimulation techniques in Alzheimer’s disease: a bibliometric analysis

Correction: Altered dynamic functional network connectivity patterns in Alzheimer's disease: insights into neural dysfunction

Unveiling the glymphatic system’s impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012–2024)

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease