Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Brief Research Report

Published on 26 Mar 2025

From genes to drugs: targeting Alzheimer’s with circadian insights

in Alzheimer's Disease and Related Dementias

Zekun Li
Xiaohan Li
Lei Su
Zibo Zhang
Hongmin Guo
Yihao Ge
Fang Dong
Feng Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527636

1,982 views

Original Research

Published on 24 Mar 2025

Effect of chronic alcohol feeding using the Lieber-DeCarli diet on Alzheimer’s disease pathology in Tg2576 mice

in Alzheimer's Disease and Related Dementias

Devaraj V. Chandrashekar
Nataraj Jagadeesan
Tamara Abdullah
Rudy Chang
Ross A. Steinberg
Frankey Sanchez
Elias Khal
Joshua Yang
David H. Cribbs
Derick Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1526571

1,854 views

Original Research

Published on 24 Mar 2025

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Hussam Z. Alshareef
Thomas Ballinger
Everett Rojas
Alexander M. van der Linden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1464015

1,738 views
1 citation

Methods

Published on 21 Mar 2025

An imaging and genetic-based deep learning network for Alzheimer's disease diagnosis

in Alzheimer's Disease and Related Dementias

Yuhan Li
Donghao Niu
Keying Qi
Dong Liang
Xiaojing Long

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1532470

2,208 views

Original Research

Published on 20 Mar 2025

Parishin A ameliorates cognitive decline by promoting PS1 autophagy in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Song Guo
Lilin Yi
Man Luo
Zhifang Dong
Yehong Du

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516190

2,155 views

Original Research

Published on 19 Mar 2025

Global trends and prospects of ocular biomarkers in Alzheimer’s disease: a bibliometric analysis

in Alzheimer's Disease and Related Dementias

Yufei Shen
Xiaoling Zhang
Congying Xu
Zhuoying Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1528527

1,708 views

Review

Published on 14 Mar 2025

Targeting necroptosis in Alzheimer’s disease: can exercise modulate neuronal death?

in Alzheimer's Disease and Related Dementias

Donglei Lu
Wenyu Zhang
Ruiyu Li
Sijie Tan
Yan Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1499871

2,684 views

Original Research

Published on 11 Mar 2025

Global status and trends of exosomes in neurodegenerative diseases from 2014 to 2023: a bibliometric and visual analysis

in Alzheimer's Disease and Related Dementias

Hao Wu
Yao-lei Li
Pan-miao Liu
Jian-jun Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1496252

2,035 views

Editorial

Published on 11 Mar 2025

Editorial: CSF clearance in Alzheimer's disease and related dementias: exploring mechanisms and implications

in Alzheimer's Disease and Related Dementias

Yi Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1581223

1,862 views

Original Research

Published on 11 Mar 2025

Alteration of prefrontal functional connectivity in preclinical Alzheimer's disease: an fNIRS study

in Alzheimer's Disease and Related Dementias

Minhee Kim
Jang Jae Lee
Kyu Yeong Choi
Byeong C. Kim
Jeonghwan Gwak
Kun Ho Lee
Jae Gwan Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1507180

1,535 views

Editorial

Published on 05 Mar 2025

Editorial: Alzheimer's disease: new insights into biomechanisms and therapeutic target

in Alzheimer's Disease and Related Dementias

Yang Zhang
Jie Zhu
Maoli Duan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569412

1,656 views

Systematic Review

Published on 05 Mar 2025

Comparing the efficacy of physical therapy interventions in Alzheimer’s disease: a network meta-analysis

in Alzheimer's Disease and Related Dementias

Jiawen Wu
Yunfei Teng
Yaming Xie
Shuangtao Xing
Songsong Zhi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541287

3,368 views

Original Research

Published on 04 Mar 2025

Associations of varicose veins with cerebrospinal fluid biomarkers of Alzheimer’s disease pathologies in adults without dementia: the CABLE study

in Alzheimer's Disease and Related Dementias

Min Liu
Li-Yun Ma
Qiong-Yao Li
Liang-Yu Huang
He-Ying Hu
Lan Tan
Hao Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1502154

1,708 views

Original Research

Published on 04 Mar 2025

Comparing machine learning classifier models in discriminating cognitively unimpaired older adults from three clinical cohorts in the Alzheimer’s disease spectrum: demonstration analyses in the COMPASS-ND study

in Alzheimer's Disease and Related Dementias

Harrison Fah
Linzy Bohn
Russell Greiner
Roger A. Dixon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542514

1,741 views

Review

Published on 04 Mar 2025

Sex-related differences in genetically determined Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Laura Del Hoyo Soriano
Olivia Wagemann
Alexandre Bejanin
Johannes Levin
Juan Fortea

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522434

3,219 views
1 citation

Mini Review

Published on 03 Mar 2025

A mini review of transforming dementia care in China with data-driven insights: overcoming diagnostic and time-delayed barriers

in Alzheimer's Disease and Related Dementias

Pinya Lu
Xiaolu Lin
Xiaofeng Liu
Mingfeng Chen
Caiyan Li
Hongqin Yang
Yuhua Wang
Xuemei Ding

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1554834

2,023 views
1 citation