Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Review

Published on 28 Apr 2021

The Potential Role of Protein Kinase R as a Regulator of Age-Related Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Nicolás W. Martinez
Felipe E. Gómez
Soledad Matus

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.638208

7,681 views
28 citations

Review

Published on 09 Apr 2021

Neuregulins in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Guan-yong Ou
Wen-wen Lin
Wei-jiang Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.662474

12,460 views
54 citations

Mini Review

Published on 08 Apr 2021

Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue

in Cellular and Molecular Mechanisms of Brain-aging

Dmitry M. Hushpulian
Navneet Ammal Kaidery
Manuj Ahuja
Andrey A. Poloznikov
Sudarshana M. Sharma
Irina G. Gazaryan
Bobby Thomas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.673205

10,062 views
32 citations

Review

Published on 06 Apr 2021

The Emerging Role of the Interplay Among Astrocytes, Microglia, and Neurons in the Hippocampus in Health and Disease

in Cellular and Molecular Mechanisms of Brain-aging

Daniele Lana
Filippo Ugolini
Daniele Nosi
Gary L. Wenk
Maria Grazia Giovannini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.651973

10,967 views
55 citations

Review

Published on 06 Apr 2021

Transneuronal Degeneration in the Brain During Glaucoma

in Cellular and Molecular Mechanisms of Brain-aging

Mengling You
Rong Rong
Zhou Zeng
Xiaobo Xia
Dan Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.643685

9,931 views
44 citations

Original Research

Published on 22 Mar 2021

Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

in Cellular and Molecular Mechanisms of Brain-aging

Luciana Medina
Florencia González-Lizárraga
Antonio Dominguez-Meijide
Diego Ploper
Valeria Parrales
Sabrina Sequeira
Maria-Sol Cima-Omori
Markus Zweckstetter
Elaine Del Bel
Patrick P. Michel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.635760

9,696 views
22 citations

Original Research

Published on 17 Mar 2021

α-Synuclein Up-regulates Monoamine Oxidase A Expression and Activity via Trans-Acting Transcription Factor 1

in Cellular and Molecular Mechanisms of Brain-aging

Congcong Jia
Cheng Cheng
Tianbai Li
Xi Chen
Yuting Yang
Xinyao Liu
Song Li
Weidong Le

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.653379

4,413 views
11 citations

Original Research

Published on 16 Mar 2021

Absence of Pannexin 1 Stabilizes Hippocampal Excitability After Intracerebral Treatment With Aβ (1-42) and Prevents LTP Deficits in Middle-Aged Mice

in Cellular and Molecular Mechanisms of Brain-aging

Nicolina Südkamp
Olena Shchyglo
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.591735

4,244 views
11 citations

Brief Research Report

Published on 11 Mar 2021

Identification of Sox2 and NeuN Double-Positive Cells in the Mouse Hypothalamic Arcuate Nucleus and Their Reduction in Number With Aging

in Cellular and Molecular Mechanisms of Brain-aging

Ayumu Sugiura
Tatsuhiro Shimizu
Takeshi Kameyama
Tomohiko Maruo
Shin Kedashiro
Muneaki Miyata
Kiyohito Mizutani
Yoshimi Takai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.609911

6,552 views
10 citations

Brief Research Report

Published on 10 Mar 2021

Electrophysiological Properties of Substantia Gelatinosa Neurons in the Preparation of a Slice of Middle-Aged Rat Spinal Cord

in Cellular and Molecular Mechanisms of Brain-aging

Yang Li
Shanchu Su
Jiaqi Yu
Minjing Peng
Shengjun Wan
Changbin Ke

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.640265

4,745 views
4 citations

Original Research

Published on 08 Mar 2021

Dl-3-n-Butylphthalide Alleviates Demyelination and Improves Cognitive Function by Promoting Mitochondrial Dynamics in White Matter Lesions

in Cellular and Molecular Mechanisms of Brain-aging

Yiwei Feng
Min Guo
Hongchen Zhao
Sida Han
Yining Hao
Yiwen Yuan
Weiwei Shen
Jian Sun
Qiang Dong
Mei Cui

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.632374

6,891 views
14 citations

Original Research

Published on 03 Mar 2021

Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein

in Cellular and Molecular Mechanisms of Brain-aging

Ilham Y. Abdi
Nour K. Majbour
Eline A. J. Willemse
Wilma D. J. van de Berg
Brit Mollenhauer
Charlotte E. Teunissen
Omar M. El-Agnaf

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.638718

4,408 views
14 citations

Review

Published on 25 Feb 2021

Cellular Senescence in Brain Aging

in Cellular and Molecular Mechanisms of Brain-aging

Ewa Sikora
Anna Bielak-Zmijewska
Magdalena Dudkowska
Adam Krzystyniak
Grazyna Mosieniak
Malgorzata Wesierska
Jakub Wlodarczyk

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.646924

63,453 views
224 citations

Original Research

Published on 24 Feb 2021

Aging Alters Daily and Regional Calretinin Neuronal Expression in the Rat Non-image Forming Visual Thalamus

in Cellular and Molecular Mechanisms of Brain-aging

Felipe P. Fiuza
José Pablo G. Queiroz
Antônio Carlos Q. Aquino
Diego A. Câmara
Luiz Eduardo M. Brandão
Ramon H. Lima
José Rodolfo L. P. Cavalcanti
Rovena Clara G. J. Engelberth
Jeferson S. Cavalcante

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.613305

3,604 views
5 citations

Original Research

Published on 24 Feb 2021

Exogenous Alpha-Synuclein Evoked Parkin Downregulation Promotes Mitochondrial Dysfunction in Neuronal Cells. Implications for Parkinson’s Disease Pathology

in Cellular and Molecular Mechanisms of Brain-aging

Anna Wilkaniec
Anna M. Lenkiewicz
Lidia Babiec
Emilia Murawska
Henryk M. Jęśko
Magdalena Cieślik
Carsten Culmsee
Agata Adamczyk

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.591475

8,084 views
41 citations

Original Research

Published on 22 Feb 2021

The Neurocognitive Effects of Bacopa monnieri and Cognitive Training on Markers of Brain Microstructure in Healthy Older Adults

in Cellular and Molecular Mechanisms of Brain-aging

Grace M. McPhee
Luke A. Downey
Keith A. Wesnes
Con Stough

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.638109

36,447 views
12 citations