Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 11 Feb 2020

The Density of Perineuronal Nets Increases With Age in the Inferior Colliculus in the Fischer Brown Norway Rat

in Cellular and Molecular Mechanisms of Brain-aging

Amir M. Mafi
Lindsay N. Hofer
Matthew G. Russ
Jesse W. Young
Jeffrey G. Mellott

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00027

5,160 views
20 citations

Original Research

Published on 11 Feb 2020

The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells in vitro and Promotes Neurogenesis in vivo

in Cellular and Molecular Mechanisms of Brain-aging

Qingfa Chen
Hao Song
Chuanguo Liu
Jun Xu
Chuanfei Wei
Wei Wang
Fabin Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00007

6,150 views
18 citations

Review

Published on 07 Feb 2020

Microbial BMAA and the Pathway for Parkinson’s Disease Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Daniela Nunes-Costa
João Duarte Magalhães
Maria G-Fernandes
Sandra Morais Cardoso
Nuno Empadinhas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00026

38,535 views
75 citations

Perspective

Published on 07 Feb 2020

Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals

in Cellular and Molecular Mechanisms of Brain-aging

Jesse R. Poganik
Yimon Aye

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00001

4,969 views
38 citations

Mini Review

Published on 28 Jan 2020

Differences Between Human and Murine Tau at the N-terminal End

in Cellular and Molecular Mechanisms of Brain-aging

Félix Hernández
Jesús Merchán-Rubira
Laura Vallés-Saiz
Alberto Rodríguez-Matellán
Jesús Avila

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00011

15,991 views
49 citations

Original Research

Published on 22 Jan 2020

Effects of Intranasal Orexin-A (Hypocretin-1) Administration on Neuronal Activation, Neurochemistry, and Attention in Aged Rats

in Cellular and Molecular Mechanisms of Brain-aging

Coleman B. Calva
Habiba Fayyaz
Jim R. Fadel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00362

11,607 views
23 citations

Original Research

Published on 15 Jan 2020

Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus

in Cellular and Molecular Mechanisms of Brain-aging

Paula Adler
Cheng-Kang Chiang
Janice Mayne
Zhibin Ning
Xu Zhang
Bo Xu
Hai-Ying Mary Cheng
Daniel Figeys

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00368

9,043 views
30 citations

Review

Published on 10 Jan 2020

Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain

in Cellular and Molecular Mechanisms of Brain-aging

William M. Pardridge

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00373

74,571 views
306 citations

Original Research

Published on 20 Dec 2019

Mitochondrial Degeneration and Autophagy Associated With Delayed Effects of Radiation in the Mouse Brain

in Cellular and Molecular Mechanisms of Brain-aging

Neel K. Sharma
Sasha Stone
Vidya P. Kumar
Shukla Biswas
Saeed Y. Aghdam
Gregory P. Holmes-Hampton
Christine M. Fam
George N. Cox
Sanchita P. Ghosh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00357

4,658 views
15 citations

Original Research

Published on 19 Dec 2019

Regional Distributions of Iron, Copper and Zinc and Their Relationships With Glia in a Normal Aging Mouse Model

in Cellular and Molecular Mechanisms of Brain-aging

Azhaar Ashraf
Christos Michaelides
Thomas A. Walker
Antigoni Ekonomou
Maria Suessmilch
Achvini Sriskanthanathan
Semhar Abraha
Adam Parkes
Harold G. Parkes
Kalotina Geraki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00351

8,521 views
52 citations

Mini Review

Published on 06 Dec 2019

Perturbations of Ubiquitin-Proteasome-Mediated Proteolysis in Aging and Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Ashok N. Hegde
Spencer G. Smith
Lindsey M. Duke
Allison Pourquoi
Savannah Vaz

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00324

11,437 views
65 citations

Original Research

Published on 21 Nov 2019

Role of Tau Protein in Remodeling of Circadian Neuronal Circuits and Sleep

in Cellular and Molecular Mechanisms of Brain-aging

Mercedes Arnes
Maria E. Alaniz
Caline S. Karam
Joshua D. Cho
Gonzalo Lopez
Jonathan A. Javitch
Ismael Santa-Maria

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00320

9,210 views
23 citations

Original Research

Published on 20 Nov 2019

Enhanced Tau Protein Translation by Hyper-Excitation

in Cellular and Molecular Mechanisms of Brain-aging

Shunsuke Kobayashi
Toru Tanaka
Yoshiyuki Soeda
Akihiko Takashima

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00322

5,324 views
23 citations

Original Research

Published on 19 Nov 2019

Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice

in Cellular and Molecular Mechanisms of Brain-aging

Yinghua Liu
Wei Wei
Narjes Baazaoui
Fei Liu
Khalid Iqbal

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00309

5,750 views
11 citations

Review

Published on 12 Nov 2019

SIRT3 Regulation of Mitochondrial Quality Control in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Hao Meng
Wan-Yu Yan
Yu-Hong Lei
Zheng Wan
Ye-Ye Hou
Lian-Kun Sun
Jue-Pu Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00313

14,703 views
96 citations

Original Research

Published on 23 Oct 2019

Proteome Profiling of Cerebral Vessels in Rhesus Macaques: Dysregulation of Antioxidant Activity and Extracellular Matrix Proteins Contributes to Cerebrovascular Aging in Rhesus Macaques

in Cellular and Molecular Mechanisms of Brain-aging

Xia Wang
Yifan Liu
Yangjie Jia
Haotian Liu
Xinjie Bao
Zhanlong He
Wei Ge

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00293

3,828 views
10 citations