Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 20 Mar 2024

Astrocyte expression of aging-associated markers positively correlates with neurodegeneration in the frontal lobe of the rhesus macaque brain

in Cellular and Molecular Mechanisms of Brain-aging

Miranda D. Horn
Sophia C. Forest
Ahmad A. Saied
Andrew G. MacLean

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1368517

2,461 views

Brief Research Report

Published on 15 Mar 2024

Age-related increase in the expression of 11β-hydroxysteroid dehydrogenase type 1 in the hippocampus of male rhesus macaques

in Cellular and Molecular Mechanisms of Brain-aging

Alejandro Lomniczi
Selva L. Luna
Rita Cervera-Juanes
Maria-Luisa Appleman
Steven G. Kohama
Henryk F. Urbanski

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1328543

2,646 views
1 citation

Original Research

Published on 07 Mar 2024

Assessing interstitial fluid dynamics in type 2 diabetes mellitus and prediabetes cases through diffusion tensor imaging analysis along the perivascular space

in Cellular and Molecular Mechanisms of Brain-aging

Rukeye Tuerxun
Koji Kamagata
Yuya Saito
Christina Andica
Kaito Takabayashi
Wataru Uchida
Seina Yoshida
Junko Kikuta
Hiroki Tabata
Hitoshi Naito

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1362457

4,581 views
5 citations

Editorial

Published on 07 Mar 2024

Editorial: Bioinformatics analysis of single cell sequencing and multi-omics in the aging and age-associated diseases

in Cellular and Molecular Mechanisms of Brain-aging

Shouneng Peng
Ailan Wang
Junjun Ding
Lilach Soreq

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1384586

4,166 views

Review

Published on 28 Feb 2024

Sensorineural hearing loss and cognitive impairment: three hypotheses

in Cellular and Molecular Mechanisms of Brain-aging

He Zhao
Yan Wang
Limei Cui
Hanjing Wang
Sha Liu
Tiantian Liang
Dawei Liu
Jingjing Qiu
Liang Chen
Yan Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1368232

5,222 views
4 citations

Original Research

Published on 15 Feb 2024

IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice

in Cellular and Molecular Mechanisms of Brain-aging

Lauren R. Miller
Marisa A. Bickel
Stefano Tarantini
Megan E. Runion
Zoe Matacchiera
Michaela L. Vance
Clara Hibbs
Hannah Vaden
Domonkos Nagykaldi
Teryn Martin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1320808

3,968 views
1 citation

Review

Published on 04 Jan 2024

Exploring the complexities of 1C metabolism: implications in aging and neurodegenerative diseases

in Cellular and Molecular Mechanisms of Brain-aging

Ayman Bou Ghanem
Yaman Hussayni
Raghid Kadbey
Yara Ratel
Shereen Yehya
Lara Khouzami
Hilda E. Ghadieh
Amjad Kanaan
Sami Azar
Frederic Harb

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1322419

6,076 views
5 citations

Editorial

Published on 03 Jan 2024

Editorial: World digestive health day: investigating the link between neurodegenerative disease and gut microbiota

in Cellular and Molecular Mechanisms of Brain-aging

Shampa Ghosh
Sunil Dhungel
Mohd. Farooq Shaikh
Jitendra Kumar Sinha

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1351855

3,157 views
8 citations

Original Research

Published on 15 Dec 2023

The DNA repair enzyme, aprataxin, plays a role in innate immune signaling

in Cellular and Molecular Mechanisms of Brain-aging

Helena B. Madsen
Louise I. Pease
Rebekah-Louise Scanlan
Mansour Akbari
Lene J. Rasmussen
Daryl P. Shanley
Vilhelm A. Bohr

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1290681

3,932 views
1 citation

Original Research

Published on 07 Dec 2023

Proteomic signature profiling in the cortex of dairy cattle unravels the physiology of brain aging

in Cellular and Molecular Mechanisms of Brain-aging

Flora Cozzolino
Luisa Canè
Maria Claudia Gatto
Ilaria Iacobucci
Luigi Sacchettino
Davide De Biase
Evaristo Di Napoli
Orlando Paciello
Luigi Avallone
Maria Monti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1277546

1,880 views

Original Research

Published on 29 Nov 2023

Association between gene expression and altered resting-state functional networks in type 2 diabetes

in Cellular and Molecular Mechanisms of Brain-aging

Yang Zhang
Xin Du
Wen Qin
Yumeng Fu
Zirui Wang
Quan Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1290231

2,564 views
1 citation

Review

Published on 23 Nov 2023

Cellular senescence in brain aging and cognitive decline

in Cellular and Molecular Mechanisms of Brain-aging

Areez Shafqat
Saifullah Khan
Mohamed H. Omer
Mahnoor Niaz
Ibrahem Albalkhi
Khaled AlKattan
Ahmed Yaqinuddin
Tamara Tchkonia
James L. Kirkland
Shahrukh K. Hashmi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1281581

16,014 views
16 citations

Original Research

Published on 20 Nov 2023

Age-related upregulation of perineuronal nets on inferior collicular cells that project to the cochlear nucleus

in Cellular and Molecular Mechanisms of Brain-aging

Laila S. Almassri
Andrew P. Ohl
Milena C. Iafrate
Aidan D. Wade
Nick J. Tokar
Amir M. Mafi
Nichole L. Beebe
Jesse W. Young
Jeffrey G. Mellott

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1271008

2,326 views
2 citations

Original Research

Published on 07 Nov 2023

Unraveling the transcriptomic signatures of Parkinson’s disease and major depression using single-cell and bulk data

in Cellular and Molecular Mechanisms of Brain-aging

Christiana C. Christodoulou
Anna Onisiforou
Panos Zanos
Eleni Zamba Papanicolaou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1273855

6,634 views
7 citations

Original Research

Published on 02 Nov 2023

Effects of copy number variations on longevity in late-onset Alzheimer’s disease patients: insights from a causality network analysis

in Cellular and Molecular Mechanisms of Brain-aging

Yanan Hao
Chuhao Li
He Wang
Chen Ming

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1241412

2,668 views

Brief Research Report

Published on 27 Oct 2023

Preliminary evaluation of the proteomic profiling in the hippocampus of aged grazing cattle

in Cellular and Molecular Mechanisms of Brain-aging

Flora Cozzolino
Luisa Canè
Luigi Sacchettino
Maria Claudia Gatto
Ilaria Iacobucci
Claudia Gatta
Davide De Biase
Evaristo Di Napoli
Orlando Paciello
Luigi Avallone

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1274073

1,725 views