Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 01 Aug 2024

Alteration of cGAS-STING signaling pathway components in the mouse cortex and hippocampus during healthy brain aging

in Cellular and Molecular Mechanisms of Brain-aging

Sergio Passarella
Shananthan Kethiswaran
Karina Brandes
I-Chin Tsai
Kristin Cebulski
Andrea Kröger
Daniela C. Dieterich
Peter Landgraf

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1429005

3,857 views
3 citations

Original Research

Published on 19 Jul 2024

Lamivudine modulates the expression of neurological impairment-related genes and LINE-1 retrotransposons in brain tissues of a Down syndrome mouse model

in Cellular and Molecular Mechanisms of Brain-aging

Alessandra Borgognone
Maria Casadellà
María Martínez de Lagrán
Roger Paredes
Bonaventura Clotet
Mara Dierssen
Aleix Elizalde-Torrent

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1386944

8,868 views
1 citation

Correction

Published on 04 Jul 2024

Corrigendum: Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes

in Cellular and Molecular Mechanisms of Brain-aging

Yanrong Sun
Hanfei Wang
Wenjuan Wang
Jiali Lu
Jinglin Zhang
Xiaofeng Luo
Liju Luan
Ke Wang
Jing Jia
Junhao Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1072608

987 views

Correction

Published on 07 Jun 2024

Corrigendum: Multi-protection of DL0410 in ameliorating cognitive defects in D-galactose induced aging mice

in Cellular and Molecular Mechanisms of Brain-aging

Wenwen Lian
Hao Jia
Lvjie Xu
Wei Zhou
De Kang
Ailin Liu
Guanhua Du

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1419861

964 views

Brief Research Report

Published on 21 May 2024

Increased hippocampal epigenetic age in the Ts65Dn mouse model of Down Syndrome

in Cellular and Molecular Mechanisms of Brain-aging

Francesco Ravaioli
Fiorenza Stagni
Sandra Guidi
Chiara Pirazzini
Paolo Garagnani
Alessandro Silvani
Giovanna Zoccoli
Renata Bartesaghi
Maria Giulia Bacalini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1401109

1,584 views
2 citations

Mini Review

Published on 03 May 2024

Modeling of age-related neurological disease: utility of zebrafish

in Cellular and Molecular Mechanisms of Brain-aging

Tohgo Kanoh
Takamasa Mizoguchi
Ayako Tonoki
Motoyuki Itoh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1399098

2,722 views
2 citations

Review

Published on 23 Apr 2024

Emerging insights into cuproptosis and copper metabolism: implications for age-related diseases and potential therapeutic strategies

in Cellular and Molecular Mechanisms of Brain-aging

Haohui Fan
Kun Wang
Xiaofang Zhao
Bei Song
Tianci Yao
Ting Liu
Guangyu Gao
Weilin Lu
Chengyun Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1335122

4,837 views
12 citations

Original Research

Published on 04 Apr 2024

Lipocalin-type prostaglandin D synthase: a glymphopathy marker in idiopathic hydrocephalus

in Cellular and Molecular Mechanisms of Brain-aging

Namiko Nishida
Nanae Nagata
Keigo Shimoji
Naoto Jingami
Kengo Uemura
Akihiko Ozaki
Makio Takahashi
Yoshihiro Urade
Sadayuki Matsumoto
Koichi Iwasaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1364325

2,793 views
3 citations

Review

Published on 03 Apr 2024

Targeting shared pathways in tauopathies and age-related macular degeneration: implications for novel therapies

in Cellular and Molecular Mechanisms of Brain-aging

Michele Rinaldi
Antonio Pezone
Gaia Italia Quadrini
Gianmarco Abbadessa
Maria Paola Laezza
Maria Laura Passaro
Antonio Porcellini
Ciro Costagliola

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1371745

2,836 views
5 citations

Original Research

Published on 20 Mar 2024

Astrocyte expression of aging-associated markers positively correlates with neurodegeneration in the frontal lobe of the rhesus macaque brain

in Cellular and Molecular Mechanisms of Brain-aging

Miranda D. Horn
Sophia C. Forest
Ahmad A. Saied
Andrew G. MacLean

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1368517

2,773 views

Brief Research Report

Published on 15 Mar 2024

Age-related increase in the expression of 11β-hydroxysteroid dehydrogenase type 1 in the hippocampus of male rhesus macaques

in Cellular and Molecular Mechanisms of Brain-aging

Alejandro Lomniczi
Selva L. Luna
Rita Cervera-Juanes
Maria-Luisa Appleman
Steven G. Kohama
Henryk F. Urbanski

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1328543

2,902 views
1 citation

Original Research

Published on 07 Mar 2024

Assessing interstitial fluid dynamics in type 2 diabetes mellitus and prediabetes cases through diffusion tensor imaging analysis along the perivascular space

in Cellular and Molecular Mechanisms of Brain-aging

Rukeye Tuerxun
Koji Kamagata
Yuya Saito
Christina Andica
Kaito Takabayashi
Wataru Uchida
Seina Yoshida
Junko Kikuta
Hiroki Tabata
Hitoshi Naito

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1362457

5,247 views
7 citations

Editorial

Published on 07 Mar 2024

Editorial: Bioinformatics analysis of single cell sequencing and multi-omics in the aging and age-associated diseases

in Cellular and Molecular Mechanisms of Brain-aging

Shouneng Peng
Ailan Wang
Junjun Ding
Lilach Soreq

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1384586

4,487 views

Review

Published on 28 Feb 2024

Sensorineural hearing loss and cognitive impairment: three hypotheses

in Cellular and Molecular Mechanisms of Brain-aging

He Zhao
Yan Wang
Limei Cui
Hanjing Wang
Sha Liu
Tiantian Liang
Dawei Liu
Jingjing Qiu
Liang Chen
Yan Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1368232

6,435 views
6 citations

Original Research

Published on 15 Feb 2024

IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice

in Cellular and Molecular Mechanisms of Brain-aging

Lauren R. Miller
Marisa A. Bickel
Stefano Tarantini
Megan E. Runion
Zoe Matacchiera
Michaela L. Vance
Clara Hibbs
Hannah Vaden
Domonkos Nagykaldi
Teryn Martin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1320808

4,525 views
6 citations

Review

Published on 04 Jan 2024

Exploring the complexities of 1C metabolism: implications in aging and neurodegenerative diseases

in Cellular and Molecular Mechanisms of Brain-aging

Ayman Bou Ghanem
Yaman Hussayni
Raghid Kadbey
Yara Ratel
Shereen Yehya
Lara Khouzami
Hilda E. Ghadieh
Amjad Kanaan
Sami Azar
Frederic Harb

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1322419

7,285 views
5 citations