Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 07 Nov 2023

Unraveling the transcriptomic signatures of Parkinson’s disease and major depression using single-cell and bulk data

in Cellular and Molecular Mechanisms of Brain-aging

Christiana C. Christodoulou
Anna Onisiforou
Panos Zanos
Eleni Zamba Papanicolaou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1273855

6,685 views
11 citations

Original Research

Published on 02 Nov 2023

Effects of copy number variations on longevity in late-onset Alzheimer’s disease patients: insights from a causality network analysis

in Cellular and Molecular Mechanisms of Brain-aging

Yanan Hao
Chuhao Li
He Wang
Chen Ming

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1241412

2,691 views
1 citation

Brief Research Report

Published on 27 Oct 2023

Preliminary evaluation of the proteomic profiling in the hippocampus of aged grazing cattle

in Cellular and Molecular Mechanisms of Brain-aging

Flora Cozzolino
Luisa Canè
Luigi Sacchettino
Maria Claudia Gatto
Ilaria Iacobucci
Claudia Gatta
Davide De Biase
Evaristo Di Napoli
Orlando Paciello
Luigi Avallone

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1274073

1,732 views

Original Research

Published on 26 Oct 2023

Cognitive impairment in long-living adults: a genome-wide association study, polygenic risk score model and molecular modeling of the APOE protein

in Cellular and Molecular Mechanisms of Brain-aging

D. A. Kashtanova
A. A. Mamchur
I. H. Dzhumaniyazova
M. V. Ivanov
V. V. Erema
E. A. Zelenova
A. Y. Yakovchik
M. S. Gusakova
A. M. Rumyantseva
M. V. Terekhov

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1273825

2,920 views
3 citations

Review

Published on 19 Oct 2023

Brain-inhabiting bacteria and neurodegenerative diseases: the “brain microbiome” theory

in Cellular and Molecular Mechanisms of Brain-aging

Tarek Ziad Arabi
Aliyah Abdulmohsen Alabdulqader
Belal Nedal Sabbah
Abderrahman Ouban

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1240945

27,763 views
12 citations

Correction

Published on 17 Oct 2023

Corrigendum: Reduced insulin signaling targeted to serotonergic neurons but not other neuronal subtypes extends lifespan in Drosophila melanogaster

in Cellular and Molecular Mechanisms of Brain-aging

Nikolett Dravecz
Tommy Shaw
Isabella Davies
Casey Brown
Lewis Ormerod
Gin Vu
Tyler Walker
Taran Taank
Alan D. Shirras
Susan J. Broughton

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1307495

1,800 views

Original Research

Published on 02 Oct 2023

Brain-aging related protein expression and imaging characteristics of mice exposed to chronic hypoxia at high altitude

in Cellular and Molecular Mechanisms of Brain-aging

Yaxin Cao
Shundao Cao
Ri-Li Ge
Haihua Bao
Yalin Mou
Weizhong Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1268230

5,245 views
4 citations

Original Research

Published on 07 Sep 2023

Epigenetic regulation of Parkinson’s disease risk variant GPNMB cg17274742 methylation by sex and exercise from Taiwan Biobank

in Cellular and Molecular Mechanisms of Brain-aging

Yen-Chung Chen
Yi-Chia Liaw
Oswald Ndi Nfor
Chih-Hsuan Hsiao
Ji-Han Zhong
Shey-Lin Wu
Yung-Po Liaw

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1235840

3,757 views
2 citations

Mini Review

Published on 05 Sep 2023

Lactoferrin: neuroprotection against Parkinson's disease and secondary molecule for potential treatment

in Cellular and Molecular Mechanisms of Brain-aging

Furkan Eker
Ecem Bolat
Burcu Pekdemir
Hatice Duman
Sercan Karav

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1204149

6,746 views
23 citations

Original Research

Published on 30 Aug 2023

CSF metabolites associated with biomarkers of Alzheimer’s disease pathology

in Cellular and Molecular Mechanisms of Brain-aging

Ruocheng Dong
Qiongshi Lu
Hyunseung Kang
Ivonne Suridjan
Gwendlyn Kollmorgen
Norbert Wild
Yuetiva Deming
Carol A. Van Hulle
Rozalyn M. Anderson
Henrik Zetterberg

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1214932

7,600 views
11 citations

Original Research

Published on 30 Aug 2023

Transcriptome and methylome of the supraoptic nucleus provides insights into the age-dependent loss of neuronal plasticity

in Cellular and Molecular Mechanisms of Brain-aging

Derick Thompson
Abiodun E. Odufuwa
Catherine A. Brissette
John A. Watt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1223273

3,618 views
1 citation

Original Research

Published on 28 Aug 2023

Long-term environmental enrichment is associated with better fornix microstructure in older adults

in Cellular and Molecular Mechanisms of Brain-aging

Olga M. Klimecki
Maxie Liebscher
Malo Gaubert
Dayana Hayek
Alexis Zarucha
Martin Dyrba
Claudia Bartels
Katharina Buerger
Michaela Butryn
Peter Dechent

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1170879

3,769 views
3 citations

Review

Published on 23 Aug 2023

Potential benefits of medium chain fatty acids in aging and neurodegenerative disease

in Cellular and Molecular Mechanisms of Brain-aging

Ella Dunn
Biqin Zhang
Virender K. Sahota
Hrvoje Augustin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1230467

9,910 views
17 citations

Editorial

Published on 10 Aug 2023

Editorial: Molecular and cellular mechanisms of synaptopathies: emerging synaptic aging-related molecular pathways in neurological disorders

in Cellular and Molecular Mechanisms of Brain-aging

Hector Ramiro Quintá
Laura Ibanez
Carlos Cruchaga
Dario Maschi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1267033

2,011 views

Review

Published on 03 Aug 2023

Research progress of mitophagy in chronic cerebral ischemia

in Cellular and Molecular Mechanisms of Brain-aging

Mayue Yu
Manqing Zhang
Peijie Fu
Moxin Wu
Xiaoping Yin
Zhiying Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1224633

4,517 views
4 citations

Correction

Published on 02 Aug 2023

Corrigendum: CREB5 hypermethylation involved in the ganglioside GM1 therapy of Parkinson's disease

in Cellular and Molecular Mechanisms of Brain-aging

Rui Wang
Shanshan Tong
Mengdi Wang
Junjie Zou
Nan Wang
Fengjiao Sun
Xiaosheng Zhou
Jinbo Chen
Hongcai Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2023.1250440

1,275 views