Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Review

Published on 04 Jan 2023

The role of altered protein acetylation in neurodegenerative disease

in Cellular and Molecular Mechanisms of Brain-aging

Fariha Kabir
Rachel Atkinson
Anthony L. Cook
Andrew James Phipps
Anna Elizabeth King

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1025473

13,201 views
56 citations

Mini Review

Published on 22 Dec 2022

Biological age and environmental risk factors for dementia and stroke: Molecular mechanisms

in Cellular and Molecular Mechanisms of Brain-aging

Pablo Knobel
Rachel Litke
Charles V. Mobbs

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1042488

11,828 views
25 citations

Review

Published on 20 Dec 2022

Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

in Cellular and Molecular Mechanisms of Brain-aging

Simona Aversano
Carmen Caiazza
Massimiliano Caiazzo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1069482

12,431 views
26 citations

Original Research

Published on 16 Dec 2022

The identities of insulin signaling pathway are affected by overexpression of Tau and its phosphorylation form

in Cellular and Molecular Mechanisms of Brain-aging

Ningtian Ma
Yuyang Liang
Lingyun Yue
Pu Liu
Yuxia Xu
Cuiqing Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1057281

5,575 views
4 citations

Review

Published on 13 Dec 2022

Epigenetics in depression and gut-brain axis: A molecular crosstalk

in Cellular and Molecular Mechanisms of Brain-aging

Nusrat Begum
Aniket Mandhare
Kamatham Pushpa Tryphena
Saurabh Srivastava
Mohd Farooq Shaikh
Shashi Bala Singh
Dharmendra Kumar Khatri

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1048333

22,676 views
71 citations

Original Research

Published on 06 Dec 2022

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

in Cellular and Molecular Mechanisms of Brain-aging

Zofia Chrienova
David Rysanek
Patrik Oleksak
Dorota Stary
Marek Bajda
Milan Reinis
Romana Mikyskova
Ondrej Novotny
Rudolf Andrys
Adam Skarka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1048260

28,220 views
16 citations

Original Research

Published on 05 Dec 2022

Identifying crosstalk genetic biomarkers linking a neurodegenerative disease, Parkinson’s disease, and periodontitis using integrated bioinformatics analyses

in Cellular and Molecular Mechanisms of Brain-aging

Shaonan Hu
Simin Li
Wanchen Ning
Xiuhong Huang
Xiangqiong Liu
Yupei Deng
Debora Franceschi
Anthony Chukwunonso Ogbuehi
Bernd Lethaus
Vuk Savkovic

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1032401

6,238 views
20 citations

Original Research

Published on 05 Dec 2022

Fascia iliaca compartment block can reduce the incidence of early post-operative cognitive impairment in elderly patients with high-risk hip replacement

in Cellular and Molecular Mechanisms of Brain-aging

Li Tang
Bo Li
Shun Guo
Xiaoyong Zhao
Binbin He
Weiwei Liu
Rui Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1025545

3,688 views
13 citations

Review

Published on 02 Dec 2022

Role of angiotensin II in aging

in Cellular and Molecular Mechanisms of Brain-aging

Wenmin Yi
Fei Chen
Huiji Zhang
Peng Tang
Minghao Yuan
Jie Wen
Shengyuan Wang
Zhiyou Cai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1002138

9,584 views
18 citations

Original Research

Published on 29 Nov 2022

Predicting AT(N) pathologies in Alzheimer’s disease from blood-based proteomic data using neural networks

in Cellular and Molecular Mechanisms of Brain-aging

Yuting Zhang
Upamanyu Ghose
Noel J. Buckley
Sebastiaan Engelborghs
Kristel Sleegers
Giovanni B. Frisoni
Anders Wallin
Alberto Lleó
Julius Popp
Pablo Martinez-Lage

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1040001

7,213 views
14 citations

Original Research

Published on 16 Nov 2022

Positive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer’s disease

in Cellular and Molecular Mechanisms of Brain-aging

Nicola Forte
Alba Clara Fernández-Rilo
Letizia Palomba
Brenda Marfella
Fabiana Piscitelli
Paolo De Girolamo
Alfonso Di Costanzo
Vincenzo Di Marzo
Luigia Cristino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1004002

5,519 views
15 citations

Original Research

Published on 10 Nov 2022

Volumetric analysis of the aging auditory pathway using high resolution magnetic resonance histology

in Cellular and Molecular Mechanisms of Brain-aging

Eric Y. Du
Briana K. Ortega
Yuzuru Ninoyu
Robert W. Williams
Gary P. Cofer
James J. Cook
Kathryn J. Hornburg
Yi Qi
G. Allan Johnson
Rick A. Friedman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1034073

2,608 views
1 citation

Original Research

Published on 08 Nov 2022

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

in Cellular and Molecular Mechanisms of Brain-aging

Xiaoxuan Yang
Chen Chen
Dongmei Qu
Yanping Liu
Ning Wang
Haibi Wang
Youjia Fan
Yushan Zhou
Buwei Yu
Qingsheng Xue

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1028148

2,943 views
6 citations

Original Research

Published on 07 Nov 2022

Potential blood biomarkers for chronic traumatic encephalopathy: The multi-omics landscape of an observational cohort

in Cellular and Molecular Mechanisms of Brain-aging

Xintong Ge
Mengtian Guo
Meimei Li
Shishuang Zhang
Junlian Qiang
Luoyun Zhu
Lu Cheng
Wenzhu Li
Yan Wang
Jinwen Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1052765

6,303 views
8 citations

Original Research

Published on 03 Nov 2022

Multi-omics analysis reveals neuroinflammation, activated glial signaling, and dysregulated synaptic signaling and metabolism in the hippocampus of aged mice

in Cellular and Molecular Mechanisms of Brain-aging

Yinzhong Lu
Kejia Xu
Dongyang Lin
Shuyan Wang
Rao Fu
Xiaobei Deng
Giorgia Croppi
Junjie Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.964429

6,806 views
14 citations

Review

Published on 03 Nov 2022

Redox signaling and metabolism in Alzheimer's disease

in Cellular and Molecular Mechanisms of Brain-aging

M. I. Holubiec
M. Gellert
E. M. Hanschmann

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1003721

6,285 views
42 citations

Original Research

Published on 03 Nov 2022

Association of cognitive function with Neurofilament light chain in the aqueous humor of human eye

in Cellular and Molecular Mechanisms of Brain-aging

Jianhao Bai
Zhongqi Wan
Minli Wang
Xue Wu
Tianyu Wang
Yuanyuan Zhang
Yawen Xue
Hong Xu
Qing Peng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1027705

4,684 views
13 citations

Original Research

Published on 03 Nov 2022

Intercellular communication analysis of the human retinal pigment epithelial and choroidal cells predicts pathways associated with aging, cellular senescence and age-related macular degeneration

in Cellular and Molecular Mechanisms of Brain-aging

Dhanach Dhirachaikulpanich
Cyril Lagger
Kasit Chatsirisupachai
João Pedro de Magalhães
Luminita Paraoan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1016293

9,413 views
19 citations

Review

Published on 02 Nov 2022

Pluripotent stem cell strategies for rebuilding the human brain

in Cellular and Molecular Mechanisms of Brain-aging

Francesco Limone
Joseph R. Klim
Daniel A. Mordes

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1017299

9,868 views
12 citations

Review

Published on 01 Nov 2022

Neurofilaments contribution in clinic: state of the art

in Cellular and Molecular Mechanisms of Brain-aging

Constance Delaby
Olivier Bousiges
Damien Bouvier
Catherine Fillée
Anthony Fourier
Etienne Mondésert
Nicolas Nezry
Souheil Omar
Isabelle Quadrio
Benoit Rucheton

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1034684

6,544 views
36 citations

Brief Research Report

Published on 28 Oct 2022

Astrocytes exhibit diverse Ca2+ changes at subcellular domains during brain aging

in Cellular and Molecular Mechanisms of Brain-aging

Fusheng Ding
Shanshan Liang
Ruijie Li
Zhiqi Yang
Yong He
Shaofan Yang
Qingtian Duan
Jianxiong Zhang
Jing Lyu
Zhenqiao Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1029533

6,825 views
13 citations

Original Research

Published on 25 Oct 2022

Nomogram to predict postoperative cognitive dysfunction in elderly patients undergoing gastrointestinal tumor resection

in Cellular and Molecular Mechanisms of Brain-aging

Huifan Huang
Jing Chou
Yongzhong Tang
Wen Ouyang
Xiaoxia Wu
Yuan Le

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1037852

4,809 views
9 citations

Original Research

Published on 24 Oct 2022

Elevated serum nuclear factor erythroid 2-related factor 2 levels contribute to a poor prognosis after acute supratentorial intracerebral hemorrhage: A prospective cohort study

in Cellular and Molecular Mechanisms of Brain-aging

Chuan-Liu Wang
Xin-Jiang Yan
Cheng-Liang Zhang
Yan-Wen Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1014472

2,422 views
2 citations

Original Research

Published on 24 Oct 2022

The identification of the key residues E829 and R845 involved in transient receptor potential melastatin 2 channel gating

in Cellular and Molecular Mechanisms of Brain-aging

Yuhuan Luo
Shijia Chen
Fei Wu
Chunming Jiang
Marong Fang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.1033434

2,369 views

753 articles

articles

The role of altered protein acetylation in neurodegenerative disease

Biological age and environmental risk factors for dementia and stroke: Molecular mechanisms

Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

The identities of insulin signaling pathway are affected by overexpression of Tau and its phosphorylation form

Epigenetics in depression and gut-brain axis: A molecular crosstalk

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Identifying crosstalk genetic biomarkers linking a neurodegenerative disease, Parkinson’s disease, and periodontitis using integrated bioinformatics analyses

Fascia iliaca compartment block can reduce the incidence of early post-operative cognitive impairment in elderly patients with high-risk hip replacement

Role of angiotensin II in aging

Predicting AT(N) pathologies in Alzheimer’s disease from blood-based proteomic data using neural networks

Positive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer’s disease

Volumetric analysis of the aging auditory pathway using high resolution magnetic resonance histology

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

Potential blood biomarkers for chronic traumatic encephalopathy: The multi-omics landscape of an observational cohort

Multi-omics analysis reveals neuroinflammation, activated glial signaling, and dysregulated synaptic signaling and metabolism in the hippocampus of aged mice

Redox signaling and metabolism in Alzheimer's disease

Association of cognitive function with Neurofilament light chain in the aqueous humor of human eye

Intercellular communication analysis of the human retinal pigment epithelial and choroidal cells predicts pathways associated with aging, cellular senescence and age-related macular degeneration

Pluripotent stem cell strategies for rebuilding the human brain

Neurofilaments contribution in clinic: state of the art

Astrocytes exhibit diverse Ca2+ changes at subcellular domains during brain aging

Nomogram to predict postoperative cognitive dysfunction in elderly patients undergoing gastrointestinal tumor resection

Elevated serum nuclear factor erythroid 2-related factor 2 levels contribute to a poor prognosis after acute supratentorial intracerebral hemorrhage: A prospective cohort study

The identification of the key residues E829 and R845 involved in transient receptor potential melastatin 2 channel gating