Frontiers in Aging Neuroscience | Parkinson’s Disease and Aging-related Movement Disorders

Original Research

Published on 12 Feb 2026

Cognitive function is associated with the progression of non-tremor motor symptoms in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Melissa C. Gibbs
Aminette D’Souza
Charalampos Sotirakis
Trevor J. Crawford
Chrystalina A. Antoniades

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1765860

560 views

Review

Accepted on 11 Feb 2026

Neuropsychological Aspects of Impulse Control Disorders in Parkinson's Disease

in Parkinson’s Disease and Aging-related Movement Disorders

Livia Scanferla
Atbin Djamshidian

Frontiers in Aging Neuroscience

Mini Review

Accepted on 11 Feb 2026

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders

in Parkinson’s Disease and Aging-related Movement Disorders

Lydia CHOUGAR
Andrew Vo
Stéphane Lehéricy
Alain Dagher

Frontiers in Aging Neuroscience

Original Research

Accepted on 10 Feb 2026

Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's Disease

in Parkinson’s Disease and Aging-related Movement Disorders

Fayzan Chaudhry
Tae Wan Kim
Olivier Elemento
Doron Betel

Frontiers in Aging Neuroscience

Review

Accepted on 10 Feb 2026

Examination of Shared Gut Microbiome Signatures in Ageing and Parkinson's Disease

in Parkinson’s Disease and Aging-related Movement Disorders

Teddy Jia Wei Tng
Sarivin Vanan
Li Zeng
Wilson Wen Bin Goh
Sunny H Wong
Kah-Leong Lim

Frontiers in Aging Neuroscience

Systematic Review

Published on 10 Feb 2026

Potential protein blood-based biomarkers for cognitive dysfunction in Parkinson’s disease: a systematic review and network meta-analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Youxue Tu
Changmei Lu
Bao Wu
Yuping Yang
Jiapeng Li
Qingping Su
Zhenhua Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1724548

608 views

Original Research

Accepted on 09 Feb 2026

Characterizing Motor–Cognitive Associations in Parkinson's Disease Using Digital Assessments

in Parkinson’s Disease and Aging-related Movement Disorders

Avigail Lithwick Algon
William Saban

Frontiers in Aging Neuroscience

114 views

Original Research

Published on 09 Feb 2026

Neural correlates of prospective memory in Parkinson’s disease: a high-density EEG study

in Parkinson’s Disease and Aging-related Movement Disorders

Paola Santacesaria
Stefano Vicentin
Giorgia Cona

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1683562

377 views

Original Research

Published on 09 Feb 2026

Volumetric signatures of basal ganglia–thalamo–cortical and cerebello–thalamo–cortical networks in Parkinson's disease and its motor subtypes

in Parkinson’s Disease and Aging-related Movement Disorders

Fatemeh Sadeghi
Abdullah Okar
Ronak Rashedi
Christian Gerloff
Dagmar Timmann
Robert Schulz
Simone Zittel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1743479

598 views

Original Research

Published on 09 Feb 2026

Focused ultrasound enhances targeted curcumin delivery and alleviates behavioral and neuropathological deficits in a Parkinson’s disease mouse model

in Parkinson’s Disease and Aging-related Movement Disorders

Shu-Mei Yang
Sen-Hi Yeoh
Meng-Ting Lin
Ming-Yen Hsiao
Chueh-Hung Wu
Sung-Jan Lin
Wen-Shiang Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1740256

536 views

Original Research

Accepted on 05 Feb 2026

Systems-Level Molecular and Immunological Evidence Identifies Th17/Treg Modulation as a Key Mechanism of CRSJ's Neuroprotection in Parkinson's Disease

in Parkinson’s Disease and Aging-related Movement Disorders

Xun Li
Xiyu Li
ShiYa Chen
Lin Wang
Jinyan Xia
Meiling Zheng
Chutian Zhang
XiaoQian Chen
Jing Cai

Frontiers in Aging Neuroscience

138 views

Brief Research Report

Published on 04 Feb 2026

Neuromelanin, iron and MRI measurements in midbrain tissues of Parkinson’s and Alzheimer’s subjects

in Parkinson’s Disease and Aging-related Movement Disorders

Fabio A. Zucca
Clifford M. Cassidy
Michela Sturini
Lauri Tuominen
Fulvio Adorni
Victoria Cheung
Luigi Casella
David Sulzer
Gianni Pezzoli
Ioannis U. Isaias

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1672578

533 views

Original Research

Published on 04 Feb 2026

SK channel upregulation and sex-specific mechanisms drive spinal motoneuron reduced excitability with age

in Parkinson’s Disease and Aging-related Movement Disorders

Ibrahim Abdul Halim
Kalin R. Gerber
Weston B. Gelford
Cierra L. Ellington
Mohamed H. Mousa
Teresa L. Garrett
Sherif M. Elbasiouny

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1687226

738 views

Systematic Review

Published on 04 Feb 2026

Transcutaneous auricular vagus nerve stimulation may improve cognitive deficits in neuropsychiatric diseases—a systematic review

in Parkinson’s Disease and Aging-related Movement Disorders

Stefanie Theresa Jost
Fabienne Happe
Julian Koenig
Haidar S. Dafsari

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1735787

835 views

Original Research

Published on 04 Feb 2026

Artificial intelligence and multi-omics nominate TAZ as an insomnia-related diagnostic and druggable target for Parkinson’s disease patients

in Parkinson’s Disease and Aging-related Movement Disorders

Wenjing Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1727472

572 views

Original Research

Accepted on 03 Feb 2026

Financial abilities in patients with Parkinson's disease and Mild Cognitive Impairment: unveiling cognitive and neurofunctional correlates of basic and advanced financial skills

in Parkinson’s Disease and Aging-related Movement Disorders

Laura Danesin
Giulia Pagnin
Lorenza Maistrello
Giorgia Baron
Arianna Menardi
Elena Piazzalunga
Alina Menichelli
Tatiana Cattarruzza
Leonardo Rigon
Konstantinos Koutsikos

Frontiers in Aging Neuroscience

140 views

Original Research

Published on 02 Feb 2026

Exploring biomechanical differences between brain-first and body-first Parkinson’s disease subtypes using shear wave elastography: a pilot cross-sectional study

in Parkinson’s Disease and Aging-related Movement Disorders

Shuangshuang Dong
Bo Shen
Yihong Song
Haiying Zhang
Yang Zhao
Yunyang Chen
Xu Jiang
Jun Zhu
Yang Pan
Ben Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1706502

509 views

Original Research

Accepted on 31 Jan 2026

MultimodalCNN-PD: A Parkinson's Disease Diagnostics Framework Using Multimodal Convolutional Neural Network

in Parkinson’s Disease and Aging-related Movement Disorders

Umar Muhammad Ibrahim
Tongle Zhi
Haonan Liu
Xuan Wang
Chengjie Meng

Frontiers in Aging Neuroscience

183 views

Original Research

Accepted on 30 Jan 2026

Efficacy and safety of robot-assisted versus stereotactic framework deep brain stimulation for Parkinson's disease: A retrospective study

in Parkinson’s Disease and Aging-related Movement Disorders

Zhenhua Mo
Xiao-Jian Wang
Xinyi Liang
Weiming Liang
Jieru Quan
Zhengde Xie
Lian Meng

Frontiers in Aging Neuroscience

193 views

Review

Published on 29 Jan 2026

Gut-kidney-brain axis and daytime sleepiness in Parkinson's disease and chronic kidney disease: an expert narrative review

in Parkinson’s Disease and Aging-related Movement Disorders

Shanshan Yang
Canmin Zhu
Shihong Xiong
Xinyue Wang
Ke Cheng
Yuxin Wang
Na Gong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1728664

602 views

Brief Research Report

Accepted on 28 Jan 2026

Putative Sympathetic-Predominant Subtype in Body-First Parkinson's Disease is Associated with Accelerated Cognitive Decline

in Parkinson’s Disease and Aging-related Movement Disorders

Xining Liu
Zhiheng Xu
Xiuyuan Li
Chenqin Xu
Shiyu Li
Tianyu Hu
Chen Chen
Xiaoniu Liang
Yilin Tang
Jian Wang

Frontiers in Aging Neuroscience

167 views

Original Research

Accepted on 28 Jan 2026

Altered Attention and Visuospatial Abnormalities in Parkinson's Disease: Links to Attention Networks and Basal Ganglia

in Parkinson’s Disease and Aging-related Movement Disorders

Jian Song
Yanyan Li
Yuqing Zhao
Haoping Gu
Jinfeng Xu
Xianling Xu
Wei Wei
Xiehua Xue

Frontiers in Aging Neuroscience

152 views

Original Research

Published on 28 Jan 2026

Spontaneous tauopathy with parkinsonism in an aged cynomolgus macaque

in Parkinson’s Disease and Aging-related Movement Disorders

Mirai Takahashi
Daisuke Taniguchi
Manabu Funayama
Ettore Cioffi
Shusei Fukuyama
Takuya Ito
Toshi Nakajima
Ko Tsuyama
Yuanzhe Li
Satoshi Ishiko

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1715911

983 views

Original Research

Accepted on 26 Jan 2026

Development and validation of a clinical prediction model for first fall in early Parkinson's disease: A study of two fall-naive cohorts

in Parkinson’s Disease and Aging-related Movement Disorders

Yu Wang
Jianing Mei
Yunzhe Tang
Hongping Zhao
Zijun Wei
Qingliang Tao
Xueyi Han
Jiyuan Hu
Yunyun Zhang

Frontiers in Aging Neuroscience

148 views

1,022 articles

articles

Cognitive function is associated with the progression of non-tremor motor symptoms in Parkinson’s disease

Neuropsychological Aspects of Impulse Control Disorders in Parkinson's Disease

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders

Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's Disease

Examination of Shared Gut Microbiome Signatures in Ageing and Parkinson's Disease

Potential protein blood-based biomarkers for cognitive dysfunction in Parkinson’s disease: a systematic review and network meta-analysis

Characterizing Motor–Cognitive Associations in Parkinson's Disease Using Digital Assessments

Neural correlates of prospective memory in Parkinson’s disease: a high-density EEG study

Volumetric signatures of basal ganglia–thalamo–cortical and cerebello–thalamo–cortical networks in Parkinson's disease and its motor subtypes

Focused ultrasound enhances targeted curcumin delivery and alleviates behavioral and neuropathological deficits in a Parkinson’s disease mouse model

Systems-Level Molecular and Immunological Evidence Identifies Th17/Treg Modulation as a Key Mechanism of CRSJ's Neuroprotection in Parkinson's Disease

Neuromelanin, iron and MRI measurements in midbrain tissues of Parkinson’s and Alzheimer’s subjects

SK channel upregulation and sex-specific mechanisms drive spinal motoneuron reduced excitability with age

Transcutaneous auricular vagus nerve stimulation may improve cognitive deficits in neuropsychiatric diseases—a systematic review

Artificial intelligence and multi-omics nominate TAZ as an insomnia-related diagnostic and druggable target for Parkinson’s disease patients

Financial abilities in patients with Parkinson's disease and Mild Cognitive Impairment: unveiling cognitive and neurofunctional correlates of basic and advanced financial skills

Exploring biomechanical differences between brain-first and body-first Parkinson’s disease subtypes using shear wave elastography: a pilot cross-sectional study

MultimodalCNN-PD: A Parkinson's Disease Diagnostics Framework Using Multimodal Convolutional Neural Network

Efficacy and safety of robot-assisted versus stereotactic framework deep brain stimulation for Parkinson's disease: A retrospective study

Gut-kidney-brain axis and daytime sleepiness in Parkinson's disease and chronic kidney disease: an expert narrative review

Putative Sympathetic-Predominant Subtype in Body-First Parkinson's Disease is Associated with Accelerated Cognitive Decline

Altered Attention and Visuospatial Abnormalities in Parkinson's Disease: Links to Attention Networks and Basal Ganglia

Spontaneous tauopathy with parkinsonism in an aged cynomolgus macaque

Development and validation of a clinical prediction model for first fall in early Parkinson's disease: A study of two fall-naive cohorts