Frontiers in Aging Neuroscience

Original Research

Accepted on 11 Feb 2026

Effects of Aerobic Exercise and Computer-Based Cognitive Training on Cognition, Functional Independence, Quality of Life, and Salivary Cortisol Levels in Older Adults with Mild Cognitive Impairment: A Randomized Trial

Abdur Raheem Khan
Aafreen Aafreen
Ashfaque Khan
G. Shankar Ganesh
Monira I. Aldhahi
Mohammed M Alshehri
Mohammad Abu Shaphe

Frontiers in Aging Neuroscience

Original Research

Accepted on 11 Feb 2026

Age-Related Directional Asymmetry in the Rod-and-Frame Test

Miroslaw Latka
Michał Adamski
Anna Latka
Sławomir Wudarczyk
Tadeusz Sebzda
Bruce J. West

Frontiers in Aging Neuroscience

Mini Review

Accepted on 11 Feb 2026

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders

Lydia CHOUGAR
Andrew Vo
Stéphane Lehéricy
Alain Dagher

Frontiers in Aging Neuroscience

Correction

Published on 11 Feb 2026

Correction: The effect of mind–body exercise on cognitive function and neuroplasticity in elderly people with mild cognitive impairment: a systematic review and meta-analysis

Huifang Tian
Xi Yang
Jiahuan Li
Yuqi Cheng
Shui Tian
Fanfan Meng
Qinqin Zhu
Ying Shen
Tong Wang
Chuan Guo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1772273

118 views

Original Research

Published on 11 Feb 2026

Brain lipidomics for region-specific biomarker discovery in neurodegenerative diseases

Jayashankar Jayaprakash
Solomon Tebeje Gizaw
Divyavani Gowda
Hiroshi Hinou
Shin-Ichiro Nishimura
Shu-Ping Hui
Siddabasave Gowda B. Gowda

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1757306

293 views

Original Research

Published on 11 Feb 2026

Endogenous β-hydroxybutyrate and the risk of cognitive decline: a nested case-control study in the UK Biobank cohort

Youngmi Eun
John C. Newman
Ji Hyun Lee
Se-Hong Kim
Ha-Na Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1768532

166 views

Original Research

Published on 11 Feb 2026

Cortical hemodynamic responses in older stroke patients during a walking-based Stroop dual task: a functional near-infrared spectroscopy study

Xiaohan Li
Kai Tang
Yuting Zhang
Lifeng Tang
Kun Wei
Lifeng Zhou
Min Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1714618

253 views

Original Research

Published on 11 Feb 2026

Lower hippocampal volume partly mediates the association between rs6859 in the NECTIN2 gene and Alzheimer’s disease: new findings from causal mediation analysis of ADNI data

Aravind Lathika Rajendrakumar
Konstantin G. Arbeev
Olivia Bagley
Anatoliy I. Yashin
Svetlana Ukraintseva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1715773

137 views

Original Research

Accepted on 10 Feb 2026

Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's Disease

Fayzan Chaudhry
Tae Wan Kim
Olivier Elemento
Doron Betel

Frontiers in Aging Neuroscience

Original Research

Accepted on 10 Feb 2026

TAS2R38 Taster Variants-Linked MGAM Expression in Alzheimer's Disease: A Novel Target for Precision Drug Repurposing

Claire W Su
Kewei Chen
Teresa Wu
Eric M Reiman
QI WANG

Frontiers in Aging Neuroscience

Review

Accepted on 10 Feb 2026

Interconnected Roles of Astrocytes and the Blood–Brain Barrier in Parkinson's Disease: Pathological Evidence, Mechanistic Insights, and Knowledge Gaps

Anna C Stoll
Ashley S. Harms

Frontiers in Aging Neuroscience

Original Research

Accepted on 10 Feb 2026

Associations of anticholinergic burden of medication with cognitive decline and longitudinal brain atrophy in the Alzheimer's disease spectrum

Stefan Teipel
Alice Grazia
Oliver Peters
Josef Priller
Anja Schneider
Jens Wiltfang
Claudia Bartels
Björn H Schott
Frank Jessen
Emrah Duzel

Frontiers in Aging Neuroscience

Review

Accepted on 10 Feb 2026

Examination of Shared Gut Microbiome Signatures in Ageing and Parkinson's Disease

Teddy Jia Wei Tng
Sarivin Vanan
Li Zeng
Wilson Wen Bin Goh
Sunny H Wong
Kah-Leong Lim

Frontiers in Aging Neuroscience

Brief Research Report

Published on 10 Feb 2026

APOE genotypes are associated with the level of naturally occurring antibodies to amyloid-β in patients with Alzheimer’s disease

Janardan P. Pandey
Aryan M. Namboodiri
Franca Rosa Guerini
Elisabetta Bolognesi
Milena Zanzottera
Roberta Mancuso
Simone Agostini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1673361

337 views

Original Research

Published on 10 Feb 2026

Mechanistic modeling of amyloid dynamics relating to Alzheimer's disease progression

Andrzej Przekwas
Carly Norris
Harsha T. Garimella

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1730480

891 views

Systematic Review

Published on 10 Feb 2026

Potential protein blood-based biomarkers for cognitive dysfunction in Parkinson’s disease: a systematic review and network meta-analysis

Youxue Tu
Changmei Lu
Bao Wu
Yuping Yang
Jiapeng Li
Qingping Su
Zhenhua Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1724548

395 views

Mini Review

Published on 10 Feb 2026

ZCCHC17: a target for synaptic dysfunction and neuronal excitability in Alzheimer’s disease

Brittany A. Klub
Andrew F. Teich
Giuseppe P. Cortese

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1737060

307 views

Original Research

Published on 10 Feb 2026

Oxytocin restores cognitive function and attenuates neuroinflammation in chronic sleep-deprived aged rats

Hany A. Elkattawy
Mohamed El-Sherbiny
Nehal Elsherbiny
Reham M. Wahid
Sherein F. El-Sayed
Hanan A. Henidi
Randa El-Gamal
Sultan Alshehri
Syed Mohammed Basheeruddin Asdaq

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1742343

513 views

Original Research

Accepted on 09 Feb 2026

Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic

Rafael Navarro-González
Rodrigo De Luis-Garcia
Santiago Aja-Fernandez
Wei Liu
Daniel C Alexander
Frederik Barkhof
Millie Beament
Haroon R. Chughtai
Nick C. Fox
Catherine J. Mummery

Frontiers in Aging Neuroscience

Methods

Accepted on 09 Feb 2026

Standardized Protocol for Plasticity Assessment in the Aging Mouse Neocortex using Choline-Chloride Perfusion

Pia Kruse
Charlotte Schob
Kerstin Schwabe
Maximilian Lenz

Frontiers in Aging Neuroscience

Original Research

Accepted on 09 Feb 2026

The role of glutathione in cognition, cognitive effort and cognitive endurance in young and older adults

Geraldine Rodríguez-Nieto
David F. Alvarez-Anacona
Hong Li
Mark Mikkelsen
Stephan P. Swinnen

Frontiers in Aging Neuroscience

Original Research

Accepted on 09 Feb 2026

Characterizing Motor–Cognitive Associations in Parkinson's Disease Using Digital Assessments

Avigail Lithwick Algon
William Saban

Frontiers in Aging Neuroscience

Original Research

Accepted on 09 Feb 2026

Cross-sectional and longitudinal functional network alter-ations associated with subthreshold depressive symptoms in healthy older adults

Julia Christl
Pascal Grumbach
Camilla Mendl-Heinisch
Christiane Jockwitz
Eva Meisenzahl
Svenja Caspers

Frontiers in Aging Neuroscience

7,802 Publications

volumes

Volume 18 - 2026

Effects of Aerobic Exercise and Computer-Based Cognitive Training on Cognition, Functional Independence, Quality of Life, and Salivary Cortisol Levels in Older Adults with Mild Cognitive Impairment: A Randomized Trial

Age-Related Directional Asymmetry in the Rod-and-Frame Test

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders

Correction: The effect of mind–body exercise on cognitive function and neuroplasticity in elderly people with mild cognitive impairment: a systematic review and meta-analysis

Brain lipidomics for region-specific biomarker discovery in neurodegenerative diseases

Endogenous β-hydroxybutyrate and the risk of cognitive decline: a nested case-control study in the UK Biobank cohort

Cortical hemodynamic responses in older stroke patients during a walking-based Stroop dual task: a functional near-infrared spectroscopy study

Lower hippocampal volume partly mediates the association between rs6859 in the NECTIN2 gene and Alzheimer’s disease: new findings from causal mediation analysis of ADNI data

Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's Disease

TAS2R38 Taster Variants-Linked MGAM Expression in Alzheimer's Disease: A Novel Target for Precision Drug Repurposing

Interconnected Roles of Astrocytes and the Blood–Brain Barrier in Parkinson's Disease: Pathological Evidence, Mechanistic Insights, and Knowledge Gaps

Associations of anticholinergic burden of medication with cognitive decline and longitudinal brain atrophy in the Alzheimer's disease spectrum

Examination of Shared Gut Microbiome Signatures in Ageing and Parkinson's Disease

APOE genotypes are associated with the level of naturally occurring antibodies to amyloid-β in patients with Alzheimer’s disease

Mechanistic modeling of amyloid dynamics relating to Alzheimer's disease progression

Potential protein blood-based biomarkers for cognitive dysfunction in Parkinson’s disease: a systematic review and network meta-analysis

ZCCHC17: a target for synaptic dysfunction and neuronal excitability in Alzheimer’s disease

Oxytocin restores cognitive function and attenuates neuroinflammation in chronic sleep-deprived aged rats

Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic

Standardized Protocol for Plasticity Assessment in the Aging Mouse Neocortex using Choline-Chloride Perfusion

The role of glutathione in cognition, cognitive effort and cognitive endurance in young and older adults

Characterizing Motor–Cognitive Associations in Parkinson's Disease Using Digital Assessments

Cross-sectional and longitudinal functional network alter-ations associated with subthreshold depressive symptoms in healthy older adults

Volume 17 - 2025

Astaxanthin as a neuroprotective modulator of synaptic plasticity, learning, and memory: mechanistic insights and therapeutic perspectives in neurodegenerative aging