Frontiers in Aging Neuroscience

Systematic Review

Published on 09 Oct 2025

Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis

Reema Priyanka Suram
Rida Fatima
Rajesh Madhuvilakku
Jin Ho Jung
Sang Jin Kim
Yonggeun Hong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637881

1,712 views

Original Research

Published on 09 Oct 2025

Tortuous extracranial arteries contribute to white Matter hyperintensities in aging brains

Zhe Sun
Chenyang Li
Arjun V. Masurkar
Marco Muccio
Thomas Wisniewski
Yulin Ge

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1641214

1,276 views

Original Research

Published on 08 Oct 2025

In vivo quantification of superficial cortical veins on susceptibility-weighted imaging with artificial intelligence image segmentation and the potential mechanism of human cognitive decline

Qi Xie
Hai-Xia Xu
Ya-Jie Wang
Hui-Xian Chen
Xiao-Fang Tu
Peng-Peng Han
Jun Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1557397

1,569 views

Systematic Review

Published on 07 Oct 2025

Cognitive changes preceding Parkinson's disease: a systematic review and meta-analysis of prospective population-based studies

Noelia Peña Arauzo
Christoph Theyer
Florian Krismer
Atbin Djamshidian
Werner Poewe
Corinne Horlings
Beatrice Heim
Laura Zamarian
Philipp Mahlknecht

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627221

2,161 views

Review

Published on 07 Oct 2025

Kynurenine pathway: a possible new mechanism for exercise in the prevention and treatment of Alzheimer's disease

Gangqiang Li
Shuang Li
Wenhui Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617690

2,096 views

Original Research

Published on 06 Oct 2025

The association between chronic rhinosinusitis and the risk of dementia: a longitudinal study

Xinyu Zhang
Zhongmin Yin
Jia Luo
Runsheng Yang
Weijing Wang
Dongfeng Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609790

2,437 views

Mini Review

Published on 06 Oct 2025

Biomarkers of balance and gait deficits in FMR1 premutation carriers: a mini-review

Leila C. Moore
Nell Maltman
Jonathan S. Lee-Confer
Megan J. Kobel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637819

1,397 views

Original Research

Published on 02 Oct 2025

Predictive gene expression signatures for Alzheimer’s disease using post-mortem brain tissue

Ashley H. Duche
Oliver Tan
Andrius Baskys
Rachita K. Sumbria
Moom R. Roosan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1591946

2,595 views
1 citation

Review

Published on 02 Oct 2025

Role of lipocalin-2 in amyotrophic lateral sclerosis

Zhuoya Wang
Wen Cao
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1672903

2,685 views

Review

Published on 01 Oct 2025

The microbiota–gut–brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention

Lidya K. Yassin
Jurga Skrabulyte-Barbulescu
Shamsa H. Alshamsi
Sara Saeed
Shamma H. Alkuwaiti
Saif Almazrouei
Abeer Alnuaimi
Shamsa BaniYas
Dana Aldhaheri
Mahra Alderei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1667448

11,803 views
2 citations

Original Research

Published on 01 Oct 2025

Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model

Ji Sun Lim
Soyoung Kwak
Mi-Hee Yu
Mee-Na Park
Hye Suk Baek
Junho Kang
Jeong-Ho Hong
Jin Kyung Kim
Hye Won Lee
Sang-Woo Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1644988

2,341 views

Original Research

Published on 30 Sep 2025

Five-year dementia prediction and decision support system based on real-world data

Themis P. Exarchos
George A. Dimakopoulos
Konstantinos Lazaros
Marios Krokidis
Aristidis Vrahatis
Gerasimos Grammenos
Antigoni Avramouli
Konstantina Skolariki
Roy Adams
Vasiliki Mahairaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1670609

2,837 views

Original Research

Published on 26 Sep 2025

A 15-year bibliometric analysis of body mass index moderation in the management of Parkinson’s disease

Qiying Liu
Ying Chen
Shuyi Chen
Tao Qiu
Ziyi Guo
Yuqiang Lu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1614719

1,883 views

Original Research

Published on 26 Sep 2025

EEG-based minimum spanning tree analysis reveals network disruptions in Alzheimer’s disease spectrum: an observational study

Xing Ye
Yixin Yan
Yingying Wang
Jingping Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1604345

1,950 views

Methods

Published on 25 Sep 2025

Current application status of non-invasive brain stimulation techniques in Alzheimer’s disease: a bibliometric analysis

Shan Cong
Meng Wang
Long Yan
Li Sun
Bowen Zheng
Jinying Xie
Tao Yu
Yulin Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1585885

2,802 views
1 citation

Mini Review

Published on 25 Sep 2025

Role of store-operated Ca2+ entry and STIM2 in retinal neurodegeneration during glaucoma

Sofiia Baranykova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657590

2,472 views

Review

Published on 25 Sep 2025

Current aspects of targeting cellular senescence for the therapy of neurodegenerative diseases

Ravindran Jaganathan
Ashok Iyaswamy
Senthilkumar Krishnamoorthi
Abhimanyu Thakur
Siva Sundara Kumar Durairajan
Chuanbin Yang
Dapkupar Wankhar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627921

3,972 views
1 citation

Systematic Review

Published on 25 Sep 2025

Effects of three aerobic exercise modalities (walking, running, and cycling) on circulating brain-derived neurotrophic factor in older adults: a systematic review and meta-analysis

Yang Cheng
Yuxiang Liu
Jing Ma
Zhen Li
Enli Han
Shumin Bo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1673786

3,424 views

Original Research

Published on 25 Sep 2025

Early-life hearing loss induces persistent cognitive deficits: evidence from human data and a mouse model with environmental intervention

Xuehua Zhou
Huiqian Yu
Yiru Wang
Kaizheng Chen
Xia Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1662732

1,777 views

Correction

Published on 25 Sep 2025

Correction: Altered dynamic functional network connectivity patterns in Alzheimer's disease: insights into neural dysfunction

Xuerui Pang
Yi Ji
Chenyang Hu
Yulong Dai
Panpan Hu
Xingqi Wu
Kai Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693649

1,201 views

Original Research

Published on 25 Sep 2025

Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study

Qingjuan Ren
Shu Niu
Lei Zhi
Hongfang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1667405

2,194 views

Opinion

Published on 24 Sep 2025

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

Jia-Wei Shi
Xiu-Li Meng
Yu Ye
Yi-Ting Wang
He-Xuan Ding
Wen-Xu Qi
Rui Feng
Ke Zhang
Ming Lei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675694

2,209 views

Systematic Review

Published on 24 Sep 2025

Unveiling the glymphatic system’s impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012–2024)

Younian Wang
Qiangsheng Liu
Junyi Wu
Kun Meng
Lanting Zhou
Fan Ye

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598608

4,062 views
2 citations

Original Research

Published on 24 Sep 2025

Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study

Dashan Li
Yongjie Yin
Shan Jiang
Jiuyu Yin
Luyao Yu
Nan Feng
Zhaohua Sun
Zilian Chen
Hongting Xu
Yu Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1660734

1,912 views

747 Publications

volumes

Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis

Tortuous extracranial arteries contribute to white Matter hyperintensities in aging brains

In vivo quantification of superficial cortical veins on susceptibility-weighted imaging with artificial intelligence image segmentation and the potential mechanism of human cognitive decline

Cognitive changes preceding Parkinson's disease: a systematic review and meta-analysis of prospective population-based studies

Kynurenine pathway: a possible new mechanism for exercise in the prevention and treatment of Alzheimer's disease

The association between chronic rhinosinusitis and the risk of dementia: a longitudinal study

Biomarkers of balance and gait deficits in FMR1 premutation carriers: a mini-review

Predictive gene expression signatures for Alzheimer’s disease using post-mortem brain tissue

Role of lipocalin-2 in amyotrophic lateral sclerosis

The microbiota–gut–brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention

Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model

Five-year dementia prediction and decision support system based on real-world data

A 15-year bibliometric analysis of body mass index moderation in the management of Parkinson’s disease

EEG-based minimum spanning tree analysis reveals network disruptions in Alzheimer’s disease spectrum: an observational study

Current application status of non-invasive brain stimulation techniques in Alzheimer’s disease: a bibliometric analysis

Role of store-operated Ca2+ entry and STIM2 in retinal neurodegeneration during glaucoma

Current aspects of targeting cellular senescence for the therapy of neurodegenerative diseases

Effects of three aerobic exercise modalities (walking, running, and cycling) on circulating brain-derived neurotrophic factor in older adults: a systematic review and meta-analysis

Early-life hearing loss induces persistent cognitive deficits: evidence from human data and a mouse model with environmental intervention

Correction: Altered dynamic functional network connectivity patterns in Alzheimer's disease: insights into neural dysfunction

Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

Unveiling the glymphatic system’s impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012–2024)

Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study