Frontiers in Aging Neuroscience

Original Research

Published on 12 Aug 2024

Characterizing the clinical heterogeneity of early symptomatic Alzheimer’s disease: a data-driven machine learning approach

Xiwu Wang
Teng Ye
Deguo Jiang
Wenjun Zhou
Jie Zhang
for the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1410544

3,445 views
2 citations

Original Research

Published on 09 Aug 2024

Modeling APOE ε4 familial Alzheimer’s disease in directly converted 3D brain organoids

Yunkyung Kim
Hongwon Kim
Byounggook Cho
Saemin An
Soi Kang
Sumin Kim
Jongpil Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1435445

4,432 views
7 citations

Review

Published on 09 Aug 2024

Alzheimer’s disease: a review on the current trends of the effective diagnosis and therapeutics

Aimi Syamima Abdul Manap
Reema Almadodi
Shirin Sultana
Maheishinii Grace Sebastian
Kenil Sureshbhai Kavani
Vanessa Elle Lyenouq
Aravind Shankar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1429211

20,830 views
29 citations

Original Research

Published on 08 Aug 2024

O-GlcNAc impacts mitophagy via the PINK1-dependent pathway

Ibtihal M. Alghusen
Marisa S. Carman
Heather M. Wilkins
Taylor A. Strope
Caleb Gimore
Halyna Fedosyuk
Jad Shawa
Sophiya John Ephrame
Aspin R. Denson
Xiaowan Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1387931

7,711 views
11 citations

Systematic Review

Published on 08 Aug 2024

Gut microbiota changes in patients with Alzheimer’s disease spectrum based on 16S rRNA sequencing: a systematic review and meta-analysis

Hui Li
Xiaopan Cui
Yuxiu Lin
Fengqiong Huang
Ayong Tian
Rongwei Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1422350

7,703 views
22 citations

Original Research

Published on 08 Aug 2024

The memory binding test can anticipate Alzheimer’s disease diagnosis at an early preclinical stage: a longitudinal study in the INSIGHTpreAD cohort

Filipa Raposo Pereira
Nathalie George
Gianfranco Dalla Barba
Bruno Dubois
Valentina La Corte

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1414419

3,002 views
3 citations

Original Research

Published on 07 Aug 2024

Association between a combination of cognitively stimulating leisure activities and long-chain polyunsaturated fatty acid intake on cognitive decline among community-dwelling older Japanese individuals

Hisanori Tokuda
Chika Horikawa
Yukiko Nishita
Yoshihisa Kaneda
Hidenori Obata
Tomohiro Rogi
Takayuki Izumo
Masaaki Nakai
Hiroshi Shimokata
Rei Otsuka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1406079

2,726 views

Original Research

Published on 07 Aug 2024

The involvement of effector memory CD4+ T cells in mediating the impact of genus Oscillibacter gut microbiota on Alzheimer’s disease: a Mendelian randomization study

Huachang Zhang
Yudong Wang
Hui Zhao
Wei Wang
Fabin Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423707

3,565 views
3 citations

Original Research

Published on 07 Aug 2024

Second language learning in older adults modulates Stroop task performance and brain activation

Douglas H. Schultz
Alison Gansemer
Kiley Allgood
Mariah Gentz
Lauren Secilmis
Zoha Deldar
Cary R. Savage
Ladan Ghazi Saidi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1398015

3,696 views
6 citations

Original Research

Published on 07 Aug 2024

Association of peak expiratory flow with motoric cognitive risk syndrome among older adults

Hui Xu
Xiangwen Gong
Kaiwang Cui
Xuerui Li
Long Chen
Yiyi Lu
Yangfang Liao
Jianping Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1412542

4,864 views
3 citations

Original Research

Published on 07 Aug 2024

Detection of neurophysiological markers of cognitive reserve: an EEG study

Osamu Katayama
Yaakov Stern
Christian Habeck
Annabell Coors
Sangyoon Lee
Kenji Harada
Keitaro Makino
Kouki Tomida
Masanori Morikawa
Ryo Yamaguchi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1401818

3,936 views
9 citations

Original Research

Published on 07 Aug 2024

Interplay between immune cells and metabolites in epilepsy: insights from a Mendelian randomization analysis

Kai Wang
Jinwei Yang
Wenhao Xu
Lei Wang
Yu Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1400426

3,889 views

Brief Research Report

Published on 07 Aug 2024

Cortical lobar volume reductions associated with homocysteine-related subcortical brain atrophy and poorer cognition in healthy aging

Hyun Song
Pradyumna K. Bharadwaj
David A. Raichlen
Christian G. Habeck
Matthew D. Grilli
Matthew J. Huentelman
Georg A. Hishaw
Theodore P. Trouard
Gene E. Alexander

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1406394

2,263 views
1 citation

Original Research

Published on 06 Aug 2024

Cingulate sulcus sign: a descriptive analysis in a cerebral small vessel disease population

Weishuai Li
Chang Su
Zhihan Wang
Xiaoxuan Xu
Dongming Zheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1438796

4,097 views

Original Research

Published on 06 Aug 2024

The association between rs6859 in NECTIN2 gene and Alzheimer’s disease is partly mediated by pTau

Aravind Lathika Rajendrakumar
Konstantin G. Arbeev
Olivia Bagley
Anatoliy I. Yashin
Svetlana Ukraintseva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1388363

2,876 views
5 citations

Original Research

Published on 05 Aug 2024

Association between the length of stay in rehabilitation and mortality among the adults with Parkinson’s disease: 2009–2019 Korean National Health Insurance Service Databases

Suyeong Bae
Ickpyo Hong
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1428972

2,256 views
1 citation

Review

Published on 05 Aug 2024

Neural ageing and synaptic plasticity: prioritizing brain health in healthy longevity

Sheeja Navakkode
Brian K. Kennedy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1428244

21,889 views
32 citations

Original Research

Published on 02 Aug 2024

Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1–42) profoundly and progressively alters brain function throughout life

Marco Kramer
Thu-Huong Hoang
Honghong Yang
Olena Shchyglo
Juliane Böge
Ute Neubacher
Jens Colitti-Klausnitzer
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1397901

2,789 views
2 citations

Original Research

Published on 02 Aug 2024

Senescence-related genes and proteins in the development of Alzheimer’s disease: evidence from transcriptomic and Mendelian randomization analysis

Ying Liu
Jiao Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423725

4,728 views

Study Protocol

Published on 01 Aug 2024

Matching supplementary motor area-primary motor cortex paired transcranial magnetic stimulation improves motor dysfunction in Parkinson’s disease: a single-center, double-blind randomized controlled clinical trial protocol

Xiaoshun Tang
Zhexue Huang
Guangyue Zhu
Haoyuan Liang
Hui Sun
Yu Zhang
Yalin Tan
Minglong Cui
Haiyan Gong
Xijin Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1422535

3,375 views
2 citations

Original Research

Published on 01 Aug 2024

Alteration of cGAS-STING signaling pathway components in the mouse cortex and hippocampus during healthy brain aging

Sergio Passarella
Shananthan Kethiswaran
Karina Brandes
I-Chin Tsai
Kristin Cebulski
Andrea Kröger
Daniela C. Dieterich
Peter Landgraf

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1429005

5,516 views
6 citations

Original Research

Published on 31 Jul 2024

Association between preoperative sarcopenia and postoperative delirium in older patients undergoing gastrointestinal cancer surgery

Bo Dong
Dongdong Yu
Huanhuan Zhang
Pan Li
Yi Li
Chong Li
Jianli Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1416569

3,875 views
5 citations

Original Research

Published on 31 Jul 2024

Correlations of erythrocytic oligomer α-synuclein levels with age, sex and clinical variables in patients with Parkinson’s disease

Zhe Lu
Xiaohan Yu
Pengjie Li
Yiming Wang
Yeyun Deng
Xin Li
Chaodong Wang
Shun Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1437622

2,323 views
4 citations

Retraction

Published on 29 Jul 2024

Retraction: Corrigendum: 20-HETE inhibition by HET0016 decreases the blood-brain barrier permeability and brain edema after traumatic brain injury

Frontiers Editorial Office

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1469763

1,535 views

619 Publications

volumes

Characterizing the clinical heterogeneity of early symptomatic Alzheimer’s disease: a data-driven machine learning approach

Modeling APOE ε4 familial Alzheimer’s disease in directly converted 3D brain organoids

Alzheimer’s disease: a review on the current trends of the effective diagnosis and therapeutics

O-GlcNAc impacts mitophagy via the PINK1-dependent pathway

Gut microbiota changes in patients with Alzheimer’s disease spectrum based on 16S rRNA sequencing: a systematic review and meta-analysis

The memory binding test can anticipate Alzheimer’s disease diagnosis at an early preclinical stage: a longitudinal study in the INSIGHTpreAD cohort

Association between a combination of cognitively stimulating leisure activities and long-chain polyunsaturated fatty acid intake on cognitive decline among community-dwelling older Japanese individuals

The involvement of effector memory CD4+ T cells in mediating the impact of genus Oscillibacter gut microbiota on Alzheimer’s disease: a Mendelian randomization study

Second language learning in older adults modulates Stroop task performance and brain activation

Association of peak expiratory flow with motoric cognitive risk syndrome among older adults

Detection of neurophysiological markers of cognitive reserve: an EEG study

Interplay between immune cells and metabolites in epilepsy: insights from a Mendelian randomization analysis

Cortical lobar volume reductions associated with homocysteine-related subcortical brain atrophy and poorer cognition in healthy aging

Cingulate sulcus sign: a descriptive analysis in a cerebral small vessel disease population

The association between rs6859 in NECTIN2 gene and Alzheimer’s disease is partly mediated by pTau

Association between the length of stay in rehabilitation and mortality among the adults with Parkinson’s disease: 2009–2019 Korean National Health Insurance Service Databases

Neural ageing and synaptic plasticity: prioritizing brain health in healthy longevity

Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1–42) profoundly and progressively alters brain function throughout life

Senescence-related genes and proteins in the development of Alzheimer’s disease: evidence from transcriptomic and Mendelian randomization analysis

Matching supplementary motor area-primary motor cortex paired transcranial magnetic stimulation improves motor dysfunction in Parkinson’s disease: a single-center, double-blind randomized controlled clinical trial protocol

Alteration of cGAS-STING signaling pathway components in the mouse cortex and hippocampus during healthy brain aging

Association between preoperative sarcopenia and postoperative delirium in older patients undergoing gastrointestinal cancer surgery

Correlations of erythrocytic oligomer α-synuclein levels with age, sex and clinical variables in patients with Parkinson’s disease

Retraction: Corrigendum: 20-HETE inhibition by HET0016 decreases the blood-brain barrier permeability and brain edema after traumatic brain injury