Frontiers in Aging Neuroscience

Original Research

Published on 05 Aug 2025

Clinical mechanisms of repetitive transcranial magnetic stimulation in improving constipation in Parkinson’s disease patients through the gut-brain axis

Qianlan Bo
Yanmin Li
Xiayue Wang
Huijun Wang
Huimiao Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607791

2,593 views

Review

Published on 04 Aug 2025

Physical activity and neuroinflammation: a bibliometric analysis of research progress and future perspectives

Yeting Zhang
Huangyan Li
Jiangxi Yang
Huan Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602724

2,930 views

Original Research

Published on 04 Aug 2025

Sex differences in the association of cardiometabolic risk scores and blood pressure measurements with white matter hyperintensities in diverse older adults—HABS-HD

Cellas A. Hayes
Raul Vintimilla
Soumilee Chaudhuri
Michelle C. Odden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607646

2,271 views

Original Research

Published on 01 Aug 2025

Uncovering the link between incidental physical activity and inhibition of automatic responses in aging. An ERP study

Javier Sanchez-Lopez
Juan Silva-Pereyra
Sergio Manuel Sánchez-Moguel
Graciela Catalina Alatorre-Cruz
Mauricio González-López
Jorge A Sigg-Alonso
Mariana Pérez-Figueroa
Thalía Fernández

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602114

2,056 views

Original Research

Published on 31 Jul 2025

Construction of a predictive model for cognitive impairment among older adults in Northwest China

Yu Wang
Ni Wang
Yanjie Zhao
Xiaoyan Wang
Yuqin Nie
Liping Ding

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1487838

2,112 views

Original Research

Published on 31 Jul 2025

Difference between Okinawan and Dutch older adults in prefrontal brain activation

Branislava Ćurčić-Blake
Yuko Futenma
Donald Craig Willcox
Parisa Esmaeili Tazangi
Nido Dipo Wardana
Yukihiko Ueda
André Aleman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1454068

2,514 views
1 citation

Original Research

Published on 30 Jul 2025

Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index

Zhongqiang Guo
Shuang Deng
Li Li
Min Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1623148

5,760 views

Original Research

Published on 29 Jul 2025

Neuromotor functions across the lifespan: percentiles from 6 to 80 years

Tanja H. Kakebeeke
Jon Caflisch
Aziz Chaouch
Valentin Rousson
Flavia M. Wehrle
Oskar G. Jenni

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1543408

2,870 views

Review

Published on 29 Jul 2025

The interplay between physical exercise and autophagy signaling in brain health, neurodegenerative diseases and aging

Bo Gao
Li Wang
Jian Gong
Zehua Zhu
Qi Liu
Han Yuan
Haitao Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579208

6,381 views
6 citations

Editorial

Published on 29 Jul 2025

Editorial: Lifestyle and environmental influences on Alzheimer's disease: exploring the roles of diet, exercise, cognitive reserve, sleep, and air quality

Ruogu Cheng
Song Qiao
Hongquan Wang
Yan Liu
Zhengjun Wang
Guohao Wang
Pei Shang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657074

2,104 views

Original Research

Published on 28 Jul 2025

Multimodal DTI-ALPS and hippocampal microstructural signatures unveil stage-specific pathways in Alzheimer’s disease progression

Peng Yu
Lu Shen
Lijun Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609793

3,207 views
6 citations

Original Research

Published on 28 Jul 2025

Advancing the modified face name associative memory exam in cognitive aging research: insights into connectomic correlates and task reliability

Yilin Liu
Mark H. Sundman
Dalen Hinderaker
Allison Yu-Chin Chen
Jacob M. Green
Lisbeth G. Haaheim
Hannah M. Siu
Catherine Jezerc
Kaitlyn Lai
Carol Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1592678

2,168 views

Original Research

Published on 28 Jul 2025

AI-driven precision diagnosis and treatment in Parkinson’s disease: a comprehensive review and experimental analysis

Bhekisipho Twala

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1638340

7,744 views
9 citations

Systematic Review

Published on 28 Jul 2025

A bibliometric analysis of the immune system and cognitive impairment: trends from 1985 to 2024

Beibei Zou
Jinxi Xiang
Muhua Zhang
Jing Huang
Chao Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587575

3,805 views
1 citation

Brief Research Report

Published on 25 Jul 2025

Molecular targets of neuroplasticity in ischemic stroke: insights from GEO database, single-cell analysis and immune infiltration analysis

Haoyue Yang
Zekun Li
Lu Zhang
Haifeng Zhang
Yang Liu
Wei Chen
Feng Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1561282

5,027 views
1 citation

Original Research

Published on 25 Jul 2025

Modeling and validation of wearable sensor-based gait parameters in Parkinson’s disease patients with cognitive impairment

Guo Hong
Fengju Mao
Mingming Zhang
Fei Zhang
Xiangcheng Wang
Kang Ren
Zhonglue Chen
Xiaoguang Luo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1590224

2,901 views
2 citations

Review

Published on 24 Jul 2025

NMDA receptors in neurodegenerative diseases: mechanisms and emerging therapeutic strategies

Keyi Zhang
Ming Wen
Xinyue Nan
Shuaizhu Zhao
Hao Li
Yanping Ai
Houze Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1604378

5,880 views
4 citations

Original Research

Published on 24 Jul 2025

Estimating progression of Alzheimer’s disease with extracellular vesicle-related multi-omics risk models

Xiao Zhang
Sanoji Wijenayake
Shakhawat Hossain
Qian Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617611

2,810 views

Mini Review

Published on 24 Jul 2025

GLP-1R as a potential link between diabetes and Alzheimer’s disease

Shujun Li
Nanqu Huang
Mei Wang
Wendi Huang
Jingshan Shi
Yong Luo
Juan Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1601602

4,101 views
1 citation

Review

Published on 23 Jul 2025

Tau and tauopathies across primate species: implications for modeling neurodegenerative disorders

Julia C. Colwell
Marina E. Emborg

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598245

2,584 views
3 citations

Original Research

Published on 23 Jul 2025

Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways

Waqas Ahmad
Kyonghwan Choe
Riaz Ahmad
Tae Ju Park
Myeong Ok Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607289

5,129 views
4 citations

Original Research

Published on 23 Jul 2025

Neuropeptide Y mRNA expression in the aging inferior colliculus of fischer brown norway rats

Laila S. Almassri
Kristen M. Crane
Sean R. Hergenrother
Gurveer Singh
Gillian L. Barach
Melina C. Iafrate
Joshua C. Harris
Nick Tokar
Andrew P. Ohl
Jesse W. Young

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1626021

2,112 views
2 citations

Original Research

Published on 23 Jul 2025

Region-informed machine learning model for choroid plexus segmentation in Alzheimer’s disease

Liangdong Zhou
Tracy A. Butler
Xiuyuan H. Wang
Samantha A. Keil
Seyed Hani Hojjati
Tsung-Wei Hu
Mélissa Savard
Firoza Z. Lussier
Pedro Rosa-Neto
Lidia Glodzik

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1613320

2,497 views

Original Research

Published on 23 Jul 2025

Vulnerability of long-range inputome of basal forebrain in normal aging mice

Tingting Sun
Jiale Chen
Bimin Liu
Anan Li
Hui Gong
Xiangning Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1573906

2,066 views

7,799 Publications

volumes

Volume 17 - 2025

Clinical mechanisms of repetitive transcranial magnetic stimulation in improving constipation in Parkinson’s disease patients through the gut-brain axis

Physical activity and neuroinflammation: a bibliometric analysis of research progress and future perspectives

Sex differences in the association of cardiometabolic risk scores and blood pressure measurements with white matter hyperintensities in diverse older adults—HABS-HD

Uncovering the link between incidental physical activity and inhibition of automatic responses in aging. An ERP study

Construction of a predictive model for cognitive impairment among older adults in Northwest China

Difference between Okinawan and Dutch older adults in prefrontal brain activation

Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index

Neuromotor functions across the lifespan: percentiles from 6 to 80 years

The interplay between physical exercise and autophagy signaling in brain health, neurodegenerative diseases and aging

Editorial: Lifestyle and environmental influences on Alzheimer's disease: exploring the roles of diet, exercise, cognitive reserve, sleep, and air quality

Multimodal DTI-ALPS and hippocampal microstructural signatures unveil stage-specific pathways in Alzheimer’s disease progression

Advancing the modified face name associative memory exam in cognitive aging research: insights into connectomic correlates and task reliability

AI-driven precision diagnosis and treatment in Parkinson’s disease: a comprehensive review and experimental analysis

A bibliometric analysis of the immune system and cognitive impairment: trends from 1985 to 2024

Molecular targets of neuroplasticity in ischemic stroke: insights from GEO database, single-cell analysis and immune infiltration analysis

Modeling and validation of wearable sensor-based gait parameters in Parkinson’s disease patients with cognitive impairment

NMDA receptors in neurodegenerative diseases: mechanisms and emerging therapeutic strategies

Estimating progression of Alzheimer’s disease with extracellular vesicle-related multi-omics risk models

GLP-1R as a potential link between diabetes and Alzheimer’s disease

Tau and tauopathies across primate species: implications for modeling neurodegenerative disorders

Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways

Neuropeptide Y mRNA expression in the aging inferior colliculus of fischer brown norway rats

Region-informed machine learning model for choroid plexus segmentation in Alzheimer’s disease

Vulnerability of long-range inputome of basal forebrain in normal aging mice