Frontiers in Aging Neuroscience

Original Research

Published on 27 Jun 2025

Age-sex differences in Alzheimer’s and related dementias burden and risk factors in east and Southeast Asia: results from the 2021 GBD study

Tengyu Zhao
Pengyu Pan
Yuhan Zhou
Xinyue Zhang
Quan Li
Yanyan Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562148

382 views

Review

Accepted on 26 Jun 2025

Motor Symptoms of Parkinson's Disease: Critical Markers for Early AI-assisted Diagnosis

Ni Yang
Jing Liu
Dan Sun
Jiajun Ding
Lingzhi Sun
Xianghua Qi
Wei Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602426

118 views

Original Research

Accepted on 26 Jun 2025

Quantitative Assessment of Brain glymphatic Imaging Features Using Deep Learning-Based EPVS Segmentation and DTI-ALPS Analysis in Alzheimer's Disease

Chen Fen Yang
Tiantian Heng
Qi Feng
Rui Hua
Feng Shi
Zhengluan Liao
Keyin Qiao
Zhiliang Zhang
Jianliang Miao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1621106

204 views

Original Research

Accepted on 26 Jun 2025

Ginsenoside Rb1 attenuates neuroflammation via activating Wnt/β-catenin signaling pathway to exert neuroprotective effect on cerebral ischemic-reperfusion injury Authors：

Ruojing Liu
Xue Zhao
Yizhen Zhu
Lingling Fu
Junde Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1555067

135 views

Original Research

Published on 26 Jun 2025

Metformin improves age-related visual cortex dysfunction in mice by reducing noise correlation in the primary visual cortex

Xiaoming Liu
Yifeng Zhou
Jiachen Liu
Guangwei Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1572653

348 views

Original Research

Published on 26 Jun 2025

Regional network covariance patterns of white matter integrity related to cardiorespiratory fitness in healthy aging

Samantha G. Smith
Pradyumna K. Bharadwaj
David A. Raichlen
Matthew D. Grilli
Jessica R. Andrews-Hanna
Georg A. Hishaw
Matthew J. Huentelman
Theodore P. Trouard
Gene E. Alexander

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542458

346 views

Original Research

Published on 26 Jun 2025

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

Henning Peter Düsedau
Carla Cangalaya
Stoyan Stoyanov
Alexander Dityatev
Ildiko Rita Dunay

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1616390

413 views

Original Research

Accepted on 25 Jun 2025

Evaluation of non-motor symptoms in Parkinson's Disease Using Multiparametric MRI with the MULTIPLEX Sequence

He Sui
Zhanhao Mo
Feng Shi
Qing Zhou
Dan Yu
Jiaqi Wang
Lin Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602245

196 views

Review

Published on 25 Jun 2025

Necroptosis in vascular cognitive impairment: mechanisms and therapeutic potential

Shufei Wei
Lin Cheng
Chunxiao Shen
Zefen Li
Jiahui Teng
Liangliang Wang
Xiaorong Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1599773

365 views

Original Research

Published on 25 Jun 2025

Predicting amyloid status in mild cognitive impairment: the role of semantic intrusions combined with plasma biomarkers

Yao Lu
Liang Cui
Lin Huang
Fang Xie
Qi-Hao Guo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1624513

436 views

Original Research

Published on 25 Jun 2025

Voxel- and surface-based morphometry in the cortical thickness and cortical and subcortical gray matter volume in patients with mild-to-moderate Alzheimer’s disease

Kaidi Li
Dingling Xie
Zhengyong Zhang
Chunyu Fu
Chunyang Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1546977

539 views

Original Research

Published on 25 Jun 2025

Modeling heterogeneity in cognitive trajectories in the Framingham Heart Study

Yuan Fang
Jiachen Chen
Jesse Mez
Claudia L. Satizabal
Michael L. Alosco
Wei Qiao Qiu
Margaret F. Doyle
Joanne M. Murabito
Kathryn L. Lunetta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1471154

502 views

Original Research

Accepted on 24 Jun 2025

Differential methylation of SNCA and MAPT genes associated with Parkinson's Disease in Mexican Mestizos

Ernesto G Miranda-Morales
Daniel F. Ramos-Rosales
Alma C. Salas-Leal
Sergio Manuel Salas Pacheco
Francisco Xavier Castellanos-Juarez
Edna Madai Méndez Hernández
Osmel La Llave-León
María S. Peñaherrera
Gerardo Quiñones-Canales
Oscar Arias-Carrión

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1612544

126 views

Systematic Review

Accepted on 24 Jun 2025

A Bibliometric Analysis of Immune System and Cognitive Impairment: Trends from 1985 to 2024

Beibei Zou
Jinxi Xiang
Muhua Zhang
Chao Feng
Jing Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587575

Original Research

Published on 24 Jun 2025

A new pathway for neuroprotection against tau hyperphosphorylation via δ-opioid receptor initiated inhibition of CDK5 and AMPK signaling

Jiahui Li
Yuan Xu
Gianfranco Balboni
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587219

578 views

Original Research

Published on 24 Jun 2025

Cognitive function changes and DTI-ALPS index in postmenopausal women

Ningning Liu
Yue Zhang
Weiqing Fu
Huijun Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1593366

479 views

7,346 Publications

Volume 17 - 2025

Age-sex differences in Alzheimer’s and related dementias burden and risk factors in east and Southeast Asia: results from the 2021 GBD study

Motor Symptoms of Parkinson's Disease: Critical Markers for Early AI-assisted Diagnosis

Quantitative Assessment of Brain glymphatic Imaging Features Using Deep Learning-Based EPVS Segmentation and DTI-ALPS Analysis in Alzheimer's Disease

Ginsenoside Rb1 attenuates neuroflammation via activating Wnt/β-catenin signaling pathway to exert neuroprotective effect on cerebral ischemic-reperfusion injury Authors：

Metformin improves age-related visual cortex dysfunction in mice by reducing noise correlation in the primary visual cortex

Regional network covariance patterns of white matter integrity related to cardiorespiratory fitness in healthy aging

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

Evaluation of non-motor symptoms in Parkinson's Disease Using Multiparametric MRI with the MULTIPLEX Sequence

Necroptosis in vascular cognitive impairment: mechanisms and therapeutic potential

Predicting amyloid status in mild cognitive impairment: the role of semantic intrusions combined with plasma biomarkers

Voxel- and surface-based morphometry in the cortical thickness and cortical and subcortical gray matter volume in patients with mild-to-moderate Alzheimer’s disease

Modeling heterogeneity in cognitive trajectories in the Framingham Heart Study

Differential methylation of SNCA and MAPT genes associated with Parkinson's Disease in Mexican Mestizos

A Bibliometric Analysis of Immune System and Cognitive Impairment: Trends from 1985 to 2024

A new pathway for neuroprotection against tau hyperphosphorylation via δ-opioid receptor initiated inhibition of CDK5 and AMPK signaling

Cognitive function changes and DTI-ALPS index in postmenopausal women