Frontiers in Aging Neuroscience

Original Research

Published on 16 Apr 2025

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

Huan Chen
Fangzhen Guo
Yan Zhao
Wei Liu
Bingyu Chen
Chang Wang
Lining Huang
Sufang Jiang
Xiaowei Ma
Huiling Ren

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1572976

4,007 views
1 citation

Correction

Published on 16 Apr 2025

Corrigendum: Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults

Javier Oltra
Grégoria Kalpouzos
Ingrid Ekström
Maria Larsson
Yuanjing Li
Chengxuan Qiu
Erika J. Laukka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1599273

2,325 views

Original Research

Published on 15 Apr 2025

Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset

Tianqi Xu
Zhihuai Deng
Yinhui Yu
Wenchao Duan
Zeyu Ma
Haoran Liu
Lianling Li
Moxuan Zhang
Siyu Zhou
Pengda Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1564754

3,541 views
1 citation

Methods

Published on 15 Apr 2025

The innovation and practice of the “hand as foot” teaching method in the teaching of Parkinson’s disease

Jingjing Yang
Dandan Yang
Jie Yu
Jiahui Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1519067

2,308 views
1 citation

Original Research

Published on 15 Apr 2025

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

Alexandre Guimarães de Almeida Barros
Thayana Oliveira Soares
Ariane Flávia Almeida Lage
Marco Túlio Gualberto Cintra
Jonas Jardim de Paula
Olívio Brito Malheiro
Antonio Eiras Falcão
Christiano Altamiro Coli Nogueira
Leandro Braz de Carvalho
Marco Aurélio Romano Silva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1557016

2,737 views

Original Research

Published on 15 Apr 2025

Decoding immune cell dynamics in ischemic stroke: insights from single-cell RNA sequencing analysis

Yating Lan
Chun Zou
Feiyu Nong
Qi Huang
Jingyi Zeng
Wenyi Song
Guining Liang
Qingyan Wei
Mika Pan
Donghua Zou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549518

4,575 views
1 citation

Original Research

Published on 14 Apr 2025

Large inter-arm systolic blood pressure difference is associated with cognitive impairment in older adults: a cross-sectional study in rural southwest China

Qingyue Wu
Jingyuan Yang
Xunqiong Zhou
Mingyan Chen
Xing Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1489033

2,311 views

Original Research

Published on 14 Apr 2025

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

Manal Aljuhani

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547185

2,030 views
1 citation

Original Research

Published on 14 Apr 2025

Association between hemoglobin-to-red blood cell distribution width ratio and cognitive function in older US adults: a cross-sectional study based on the NHANES 2011–2014

Fan Wang
Xiangyang Wang
Chaowei Wang
Hao Liu
Zhixiu Xu
Dongli Li
Xiaowen Zhao
Jialu Zhao
Shaomin Li
Jianhua Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571159

3,493 views
1 citation

Systematic Review

Published on 14 Apr 2025

Meta-analysis of the effects of multi-component exercise on cognitive function in older adults with cognitive impairment

Hualei Liu
Zhiyuan Sun
Haiqing Zeng
Jincheng Han
Mengqi Hu
Dewei Mao
Xuewen Tian
Ran Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1551877

7,604 views
9 citations

Original Research

Published on 11 Apr 2025

Normative characterization of age-related periodic and aperiodic activity in resting-state real-world clinical EEG recordings

Sophie Leroy
Viktor Bublitz
Falk von Dincklage
Daria Antonenko
Robert Fleischmann

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540040

3,086 views
7 citations

Original Research

Published on 11 Apr 2025

Uncovering unseen ties: a network analysis explores activities of daily living limitations and depression among Chinese older adults

Hongbo Sun
Youcai Zhou
Xianqiang Zhang
Zhongxin Liang
Jinlan Chen
Ping Zhou
Xinjie Xue

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527774

4,274 views
1 citation

Original Research

Published on 11 Apr 2025

Bundled assessment to replace on-road test on driving function in stroke patients: a binary classification model via random forest

Lu Huang
Xin Liu
Jiang Yi
Yu-Wei Jiao
Tian-Qi Zhang
Guang-Yao Zhu
Shu-Yue Yu
Zhong-Liang Liu
Min Gao
Xiao-Qin Duan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1503672

2,057 views
1 citation

Original Research

Published on 11 Apr 2025

Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation

Meixi Li
Jiaxi Song
Xiaoli Niu
Feng Mo
Xiaohua Xie
Xiuqin Li
Yu Yin
Tianjun Wang
Xiujuan Song
Jingze Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1521353

2,706 views
1 citation

Original Research

Published on 11 Apr 2025

Explainable graph neural network based on metabolic brain imaging for differential diagnosis of parkinsonism

Ronghua Ling
Xingxing Cen
Shaoyou Wu
Min Wang
Ying Zhang
Juanjuan Jiang
Jiaying Lu
Yingqian Liu
Chuantao Zuo
Jiehui Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1580910

3,899 views
3 citations

Systematic Review

Published on 10 Apr 2025

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

Serena Dattola
Augusto Ielo
Giuseppe Varone
Alberto Cacciola
Angelo Quartarone
Lilla Bonanno

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547727

7,531 views
5 citations

Correction

Published on 09 Apr 2025

Corrigendum: Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in parkinsonian brain via an Nrf2-driven Wnt/β-catenin prosurvival axis

Maria Francesca Serapide
Francesca L'Episcopo
Cataldo Tirolo
Nunzio Testa
Salvatore Caniglia
Carmela Giachino
Bianca Marchetti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1596878

1,210 views

Systematic Review

Published on 09 Apr 2025

Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review

Bo Yang
Xia Deng
Xianfeng Qu
Yingjie Li
Lei Guo
Nengwei Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1492800

3,681 views

Original Research

Published on 09 Apr 2025

Knowledge of Parkinson’s disease among non-PD specialists: a web-based survey in South China

Shaohua Lyu
Zhe Li
Zhenhui Mao
Jingbo Sun
Chunye Zheng
Qiaozhen Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1488009

2,786 views

Original Research

Published on 09 Apr 2025

Machine learning study on predicting depressive symptoms and genetic correlations in Parkinson’s disease

Haijun Zhang
Yifan Zhang
Guihua Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584005

2,512 views

Original Research

Published on 09 Apr 2025

Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study

Ling Li
Xiaoxiao Zheng
Hongyue Ma
Mingxia Zhu
Xiuli Li
Xinhong Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1556608

3,454 views
1 citation

Review

Published on 08 Apr 2025

Alzheimer's disease and insomnia: a bibliometric study and visualization analysis

Zi-Yue Tian
Bing Jiang
Meng Jin
Xiao-Kun Yu
Qi-Lin Chen
Jia-Hui Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542607

6,038 views
3 citations

Original Research

Published on 08 Apr 2025

Predictors of white matter hyperintensities in the elderly Congolese population

Emile Omba Yohe
Alvaro Alonso
Daniel L. Drane
Saranya Sundaram Patel
Megan Schwinne
Emmanuel Epenge
Guy Gikelekele
Esambo Herve
Immaculee Kavugho
Nathan Tshengele

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1491477

2,433 views

Review

Published on 08 Apr 2025

Research progress on resistance exercise therapy for improving cognitive function in patients with AD and muscle atrophy

Wenyao Li
Wei Fang
Yier Zhang
Qiulu Chen
Wuyue Shentu
Qilun Lai
Lin Cheng
Sicheng Yan
Qi Kong
Song Qiao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552905

6,148 views
3 citations

7,808 Publications

volumes

Volume 17 - 2025

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

Corrigendum: Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults

Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset

The innovation and practice of the “hand as foot” teaching method in the teaching of Parkinson’s disease

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

Decoding immune cell dynamics in ischemic stroke: insights from single-cell RNA sequencing analysis

Large inter-arm systolic blood pressure difference is associated with cognitive impairment in older adults: a cross-sectional study in rural southwest China

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

Association between hemoglobin-to-red blood cell distribution width ratio and cognitive function in older US adults: a cross-sectional study based on the NHANES 2011–2014

Meta-analysis of the effects of multi-component exercise on cognitive function in older adults with cognitive impairment

Normative characterization of age-related periodic and aperiodic activity in resting-state real-world clinical EEG recordings

Uncovering unseen ties: a network analysis explores activities of daily living limitations and depression among Chinese older adults

Bundled assessment to replace on-road test on driving function in stroke patients: a binary classification model via random forest

Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation

Explainable graph neural network based on metabolic brain imaging for differential diagnosis of parkinsonism

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

Corrigendum: Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in parkinsonian brain via an Nrf2-driven Wnt/β-catenin prosurvival axis

Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review

Knowledge of Parkinson’s disease among non-PD specialists: a web-based survey in South China

Machine learning study on predicting depressive symptoms and genetic correlations in Parkinson’s disease

Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study

Alzheimer's disease and insomnia: a bibliometric study and visualization analysis

Predictors of white matter hyperintensities in the elderly Congolese population

Research progress on resistance exercise therapy for improving cognitive function in patients with AD and muscle atrophy

volumes

Volume 17 - 2025

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

Corrigendum: Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults

Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset

The innovation and practice of the “hand as foot” teaching method in the teaching of Parkinson’s disease

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

Decoding immune cell dynamics in ischemic stroke: insights from single-cell RNA sequencing analysis

Large inter-arm systolic blood pressure difference is associated with cognitive impairment in older adults: a cross-sectional study in rural southwest China

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

Association between hemoglobin-to-red blood cell distribution width ratio and cognitive function in older US adults: a cross-sectional study based on the NHANES 2011–2014

Meta-analysis of the effects of multi-component exercise on cognitive function in older adults with cognitive impairment

Normative characterization of age-related periodic and aperiodic activity in resting-state real-world clinical EEG recordings

Uncovering unseen ties: a network analysis explores activities of daily living limitations and depression among Chinese older adults

Bundled assessment to replace on-road test on driving function in stroke patients: a binary classification model via random forest

Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation

Explainable graph neural network based on metabolic brain imaging for differential diagnosis of parkinsonism

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

Corrigendum: Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in parkinsonian brain via an Nrf2-driven Wnt/β-catenin prosurvival axis

Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review

Knowledge of Parkinson’s disease among non-PD specialists: a web-based survey in South China

Machine learning study on predicting depressive symptoms and genetic correlations in Parkinson’s disease

Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study

Alzheimer's disease and insomnia: a bibliometric study and visualization analysis

Predictors of white matter hyperintensities in the elderly Congolese population

Research progress on resistance exercise therapy for improving cognitive function in patients with AD and muscle atrophy

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice