Frontiers in Aging Neuroscience

Original Research

Published on 25 Mar 2025

Whole-brain 3D imaging of dopaminergic neurons and glial cells in the mouse model of Parkinson’s disease induced by 6-OHDA

Mengqi Wang
Linglong Xiao
Yifeng Shi
Yaping Wu
Xinyuejia Huang
Yang Wu
Yangyang Xu
Lin Bai
Wei Pan
Jie Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1503168

4,447 views

Original Research

Published on 25 Mar 2025

β2-microglobulin and cognitive decline: unraveling the mediating role of the Dunedin Pace of Aging methylation

Yujun Ke
Ping Chen
Chunlan Wu
Qinqin Wang
Kai Zeng
Min Liang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505185

3,336 views
2 citations

Original Research

Published on 24 Mar 2025

Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults

Javier Oltra
Grégoria Kalpouzos
Ingrid Ekström
Maria Larsson
Yuanjing Li
Chengxuan Qiu
Erika J. Laukka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539508

3,562 views

Original Research

Published on 24 Mar 2025

Effect of chronic alcohol feeding using the Lieber-DeCarli diet on Alzheimer’s disease pathology in Tg2576 mice

Devaraj V. Chandrashekar
Nataraj Jagadeesan
Tamara Abdullah
Rudy Chang
Ross A. Steinberg
Frankey Sanchez
Elias Khal
Joshua Yang
David H. Cribbs
Derick Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1526571

3,949 views

Original Research

Published on 24 Mar 2025

The effect of removing hearing aids on postural sway in older adults with age-related hearing loss: an experimental study

Sylwia Kolasa
Bård Bogen
Roy M. Nilsen
Frederik Goplen
Stein Helge G. Nordahl
Kjersti Thulin Wilhelmsen
Jan Erik Berge
Dara Meldrum
Susanne S. Hernes
Ole Martin Steihaug

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1534227

2,673 views
1 citation

Original Research

Published on 24 Mar 2025

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer’s disease

Hussam Z. Alshareef
Thomas Ballinger
Everett Rojas
Alexander M. van der Linden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1464015

3,007 views
2 citations

Methods

Published on 21 Mar 2025

An imaging and genetic-based deep learning network for Alzheimer's disease diagnosis

Yuhan Li
Donghao Niu
Keying Qi
Dong Liang
Xiaojing Long

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1532470

4,985 views
9 citations

Review

Published on 21 Mar 2025

Significance of nicotine and nicotinic acetylcholine receptors in Parkinson’s disease

Xia Lin
Qian Li
Min Pu
Hao Dong
Qinghua Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1535310

14,564 views
11 citations

Original Research

Published on 20 Mar 2025

Parishin A ameliorates cognitive decline by promoting PS1 autophagy in Alzheimer’s disease

Song Guo
Lilin Yi
Man Luo
Zhifang Dong
Yehong Du

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516190

3,890 views

Original Research

Published on 20 Mar 2025

Association between serum tricosanoic acid and cognitive function in older adults: findings from the NHANES and GEO databases

Ti Yang
Yue Zhang
Zeen Cai
Ying Wang
Shengqiong Deng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1534303

5,587 views
3 citations

Original Research

Published on 20 Mar 2025

Improv as cognitive activity

Kristin R. Krueger
Jeffrey P. Winer
Daniel C. Lattimore
Todd Beck
Kyle Dennis
Cameron Carswell
Clifton Saper
Mathieu Hainselin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1520698

4,626 views
3 citations

Systematic Review

Published on 19 Mar 2025

Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis

Chang Liu
Yutong Su
Yuen-ming Yau
Huize Lin
Yihao Chen
Weijian Fang
Nenggui Xu
Zhennan Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1560032

4,855 views
3 citations

Original Research

Published on 19 Mar 2025

Basic research on postoperative cognitive dysfunction in the past decade: a bibliometric analysis

Hongwei Wu
Jiannan Song
Zhanfei Hu
Haibo Li
Qi Zhou
Congcong Dai
Yi Gao
WanLi Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529860

3,802 views
5 citations

Brief Research Report

Published on 19 Mar 2025

Preserved learning despite impaired short-term memory in older adults with mild cognitive impairment

Elaina Smith
Christopher Cortez
April Wiechmann
Sandra Davis
Hannah Dyson
Krystyn Kucharski
Sarah Ross
Geoffrey Kline
Robert T. Mallet
Xiangrong Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1560791

2,571 views
3 citations

Review

Published on 19 Mar 2025

Decoding brain aging trajectory: predictive discrepancies, genetic susceptibilities, and emerging therapeutic strategies

Yulia Komleva
Kristina Shpiliukova
Nikolai Bondar
Alla Salmina
Elena Khilazheva
Sergey Illarioshkin
Michael Piradov

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562453

4,460 views
4 citations

Original Research

Published on 19 Mar 2025

Global trends and prospects of ocular biomarkers in Alzheimer’s disease: a bibliometric analysis

Yufei Shen
Xiaoling Zhang
Congying Xu
Zhuoying Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1528527

3,301 views

Systematic Review

Published on 18 Mar 2025

Association between hyperlipidemia and postoperative delirium risk: a systematic review and meta-analysis

Li-quan Qiu
Jian-li Song
Li-cai Zhang
Bin Fan
Qiang Li
Bin Lu
Guan-yu Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1544838

3,721 views
3 citations

Original Research

Published on 18 Mar 2025

Serum potassium level is associated with serum neurofilament light chain in American adult population: a cross-sectional analysis of the 2013–2014 National Health and Nutrition Examination Survey

Yingming Kong
Yanghao Tai
Bin Chen
Chunzheng Li
Hao Chen
Liang Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1511881

3,871 views
1 citation

Original Research

Published on 18 Mar 2025

The abnormal accumulation of pathological proteins and compensatory functional connectivity enhancement of insula subdivisions in mild cognitive impairment

Darui Zheng
Chen Xue
Yingcai Feng
Yiming Ruan
Wenzhang Qi
Qianqian Yuan
Zonghong Li
Chaoyong Xiao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1506478

2,407 views
2 citations

Original Research

Published on 17 Mar 2025

Linking cognitive reserve to neuropsychological outcomes and resting-state frequency bands in healthy aging

Vanesa Perez
Vanesa Hidalgo
Alicia Salvador

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540168

2,975 views
2 citations

Original Research

Published on 17 Mar 2025

Strategic delivery of omega-3 fatty acids for modulating inflammatory neurodegenerative diseases

Yixin Chen
Roni Touboul
Yao Chen
Chuchun L. Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1535094

5,214 views
5 citations

Original Research

Published on 17 Mar 2025

Preoperative continuation vs. discontinuation of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers on early cognitive function in elderly patients undergoing noncardiac surgery: a randomized controlled trial

Xiaohan Wang
Yanan Yan
Yurong Liu
Chun Xu
Jingwen Zhuang
Zhiping Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542628

2,463 views

Original Research

Published on 14 Mar 2025

Prevalence and related factors of physical function and cognitive impairment among older adults: a population-based regional cross-sectional study

Yi Zhang
Guifen Cheng
Ling Chen
Xiaoxia Wang
Lixia Lin
Qiao Huang
Jinhua Guo
Bei Gong
Tiemei Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1534824

3,944 views
2 citations

Editorial

Published on 14 Mar 2025

Editorial: Neurovascular health insights: a powerful tool to understand and prognose neurocognitive decline

Min Xia
Michael Ntim
Bin Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584895

1,942 views

7,808 Publications

volumes

Volume 17 - 2025

Whole-brain 3D imaging of dopaminergic neurons and glial cells in the mouse model of Parkinson’s disease induced by 6-OHDA

β2-microglobulin and cognitive decline: unraveling the mediating role of the Dunedin Pace of Aging methylation

Cerebrovascular burden and neurodegeneration linked to 15-year odor identification decline in older adults

Effect of chronic alcohol feeding using the Lieber-DeCarli diet on Alzheimer’s disease pathology in Tg2576 mice

The effect of removing hearing aids on postural sway in older adults with age-related hearing loss: an experimental study

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer’s disease

An imaging and genetic-based deep learning network for Alzheimer's disease diagnosis

Significance of nicotine and nicotinic acetylcholine receptors in Parkinson’s disease

Parishin A ameliorates cognitive decline by promoting PS1 autophagy in Alzheimer’s disease

Association between serum tricosanoic acid and cognitive function in older adults: findings from the NHANES and GEO databases

Improv as cognitive activity

Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis

Basic research on postoperative cognitive dysfunction in the past decade: a bibliometric analysis

Preserved learning despite impaired short-term memory in older adults with mild cognitive impairment

Decoding brain aging trajectory: predictive discrepancies, genetic susceptibilities, and emerging therapeutic strategies

Global trends and prospects of ocular biomarkers in Alzheimer’s disease: a bibliometric analysis

Association between hyperlipidemia and postoperative delirium risk: a systematic review and meta-analysis

Serum potassium level is associated with serum neurofilament light chain in American adult population: a cross-sectional analysis of the 2013–2014 National Health and Nutrition Examination Survey

The abnormal accumulation of pathological proteins and compensatory functional connectivity enhancement of insula subdivisions in mild cognitive impairment

Linking cognitive reserve to neuropsychological outcomes and resting-state frequency bands in healthy aging

Strategic delivery of omega-3 fatty acids for modulating inflammatory neurodegenerative diseases

Preoperative continuation vs. discontinuation of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers on early cognitive function in elderly patients undergoing noncardiac surgery: a randomized controlled trial

Prevalence and related factors of physical function and cognitive impairment among older adults: a population-based regional cross-sectional study

Editorial: Neurovascular health insights: a powerful tool to understand and prognose neurocognitive decline