Frontiers in Aging Neuroscience

Review

Published on 26 Nov 2025

Unvalidated efficacy and significant risks hinder clinical use of deep cervical lymphatic-venous anastomosis for Alzheimer’s disease

Rui Zhang
Ying Ying Liu
Xun Xia
Xinjun Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671741

1,174 views

Original Research

Published on 26 Nov 2025

Primitive reflexes as behavioral biomarkers of cognitive aging: associations with physical activity and resilience—a pilot study

Anna Horváth-Pápai
Eliza Eszter Tóth
István Barthalos
Zoltán Alföldi
Johanna Takács
Ferenc Ihász

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1687512

857 views

Original Research

Published on 26 Nov 2025

Clinical and neuropsychological features associated with progression in subjective cognitive decline

Rafael Villino-Rodríguez
Mirla M. Ríos-Rivera
Genoveva Montoya-Murillo
Jonathan Patricio Baldera
Salomón Salazar-Londoño
María Cruz Rodríguez-Oroz
Miguel Germán Borda
Adolfo Jiménez-Huete
Mario Riverol

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1680762

945 views

Systematic Review

Accepted on 25 Nov 2025

The Efficacy Versus Evidence Quality of Multicompomnent Exercise for Cognitive Health in Older Adults: An Umbrella Review

Weibao Liang
Chuannan Liu
Xujie Yan
Shuting Xu
Jianmin Dai
Wenbai Huang

Frontiers in Aging Neuroscience

499 views

Original Research

Accepted on 25 Nov 2025

Quantity and quality of care and staff knowledge regarding people with Parkinson's disease in long-term nursing care—"real-life" results from the German Care4PD study

Odette Fründt
Verena Caroline Lamb
Anne-Marie Hanff
Tobias Mai
Christiane Kirchner
Ali Amouzandeh
Carsten Buhmann
Rejko Krüger
Alfons Schnitzler
Martin Südmeyer

Frontiers in Aging Neuroscience

153 views

Original Research

Published on 25 Nov 2025

VPS35 D620N mutation impairs neurogenesis and promotes ferroptosis in Parkinson’s disease by using molecular docking, molecular dynamic simulation, and cellular model

Mei Jiang
Xu Deng
Zijie Qiu
Yuan Fu
Zixiong Qiu
Jiankai Zhang
Hongxia Fu
Jie Li
Yao Luo
Xiaojun Cui

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1692687

942 views

Original Research

Published on 25 Nov 2025

Multimodal MRI reveals distinct hippocampal subregional alterations in de novo Parkinson’s disease across the cognitive spectrum

Chenxi Pan
Enchun Zhao
Jingru Ren
Gaiyan Zhou
Yajie Wang
Ronggui Zhang
Yang Shen
Weiguo Liu
Jiu Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1685244

664 views

Original Research

Published on 24 Nov 2025

Preclinical Alzheimer's and vascular biomarkers alter brain aging in cognitively normal adults: a MRI-based study

Unai Torres
David Bernal
Ibai Gurrutxaga
Ainara Estanga
Pablo Martínez-Lage
Olatz Arbelaitz

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1653074

1,016 views

Original Research

Published on 24 Nov 2025

Music-induced physiological markers for detecting Alzheimer's disease using machine learning

Rodrigo Lima
Gonçalo Barradas
Sergi Bermúdez i Badia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1701970

839 views

Original Research

Accepted on 21 Nov 2025

Follicle-Stimulating Hormone Linked to Cognitive Decline and Amyloid Burden in Postmenopausal Women

Sheng-Min Wang
Chaiho Jeong
Yoo Hyun Um
Dong Woo Kang
Sunghwan Kim
Soyoung Lee
Chang Uk Lee
Howard J Aizenstein
Ki-hyun Baek
Hyun Kook Lim

Frontiers in Aging Neuroscience

285 views

Review

Accepted on 21 Nov 2025

Mechanisms to Medicines: Navigating Drug Repurposing Strategies in Alzheimer's Disease

Sara A Khan
Khushi Raza
Prachi Tiwari
Mohamed Eltenani
Syed Arman Rabbani
Suhel Parvez

Frontiers in Aging Neuroscience

235 views

Review

Published on 21 Nov 2025

Exercise regulates mitophagy to alleviate parkinsonian neurodegeneration

Chang Liu
Wei He
JianHua Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1678460

1,392 views

Original Research

Published on 20 Nov 2025

Is cognitive reserve associated with cognitive function across stroke severity? A longitudinal study among Chinese stroke patients

Yinuo Ou
Yanrong Zhang
Yalin Lv
Silian Ding
Xiangjing Kong
Hanzhang Xu
Bei Wu
Hui Wei
Juan Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1652238

896 views

Correction

Published on 19 Nov 2025

Correction: Neuroimaging insights into lung disease-related brain changes: from structure to function

Zhixi Zhang
Miao He
Yubo Liu
Zhongtian Guan
Chunlin Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1738176

557 views
1 citation

Original Research

Published on 19 Nov 2025

Delineation of the cognitive and neuropsychiatric features of Pisa syndrome in dementia with Lewy bodies

Zhou Su
Jun Kuai
Tingting Yi
Hao Wu
Jinghuan Gan
Zhihong Shi
Shuai Liu
Yong Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637930

800 views

Original Research

Published on 19 Nov 2025

MRI-derived global small vessel disease burden serves as a marker of hippocampal sclerosis and clinical stage across the probable Alzheimer’s disease continuum

Ya-Che Chen
Ting-Bin Chen
Hsin-Chieh Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1692747

1,456 views

Mini Review

Published on 19 Nov 2025

Neuroimmune dynamics and brain aging: mechanisms and consequences

Ludmila Müller
Svetlana Di Benedetto
Viktor Müller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1715045

1,235 views

Original Research

Published on 19 Nov 2025

Vitamin D-linked vulnerability and functional connectivity alterations in the superior frontal gyrus contributing to cognitive impairment in Parkinson’s disease

Lingling Lv
Lixia Qin
Shenglan Hu
Changlian Tan
Haiyan Liao
Hainan Zhang
Feng Ren
Chunyu Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657723

988 views

Original Research

Published on 19 Nov 2025

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study

Zhou Su
Mengran Liu
Jun Kuai
Tingting Yi
Yuechang Zheng
Xinran Bao
Jiyu Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630826

671 views

Original Research

Published on 19 Nov 2025

Singing for memory: neural and cognitive effects of a choral intervention in older adults

Miriam Napadow
Håkan Fischer
Maria Sandgren
Máté Magyar
Zsuzsanna Lénárd
László Harmat
Örjan de Manzano

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1679873

2,192 views

Original Research

Published on 19 Nov 2025

Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models induced by chronic administration of D-galactose and D-galactose/AlCl3

Shreshta Jain
Divya Vohora

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1676926

1,199 views

Mini Review

Accepted on 17 Nov 2025

LRP1 at the Crossroads of Aβ Clearance and Therapeutic Targeting in Alzheimer's Disease

Yuepeng Deng
Haolin Yin
Zihao Lu
Huan Lan
Wenxiong Liu
Chao Zuo
Nanfang Pan
Xiaohe Tian
Qiyong Gong

Frontiers in Aging Neuroscience

326 views

Original Research

Published on 17 Nov 2025

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Minchul Kim
Chongwon Pae
Joon Ho Moon
Inpyeong Hwang
Kyu Sung Choi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1676721

1,354 views

Review

Published on 17 Nov 2025

Research progress on the interaction between multiple organ-brain axes and perioperative neurocognitive disorders: a narrative review

Qin Shi
Wei Wu
XiaoQin Sun
YingHai Liu
JingZheng Zeng
WeiQing Li
XueMei Dai
Gu Gong
QingQing Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1710009

866 views

747 Publications

volumes

Unvalidated efficacy and significant risks hinder clinical use of deep cervical lymphatic-venous anastomosis for Alzheimer’s disease

Primitive reflexes as behavioral biomarkers of cognitive aging: associations with physical activity and resilience—a pilot study

Clinical and neuropsychological features associated with progression in subjective cognitive decline

The Efficacy Versus Evidence Quality of Multicompomnent Exercise for Cognitive Health in Older Adults: An Umbrella Review

Quantity and quality of care and staff knowledge regarding people with Parkinson's disease in long-term nursing care—"real-life" results from the German Care4PD study

VPS35 D620N mutation impairs neurogenesis and promotes ferroptosis in Parkinson’s disease by using molecular docking, molecular dynamic simulation, and cellular model

Multimodal MRI reveals distinct hippocampal subregional alterations in de novo Parkinson’s disease across the cognitive spectrum

Preclinical Alzheimer's and vascular biomarkers alter brain aging in cognitively normal adults: a MRI-based study

Music-induced physiological markers for detecting Alzheimer's disease using machine learning

Follicle-Stimulating Hormone Linked to Cognitive Decline and Amyloid Burden in Postmenopausal Women

Mechanisms to Medicines: Navigating Drug Repurposing Strategies in Alzheimer's Disease

Exercise regulates mitophagy to alleviate parkinsonian neurodegeneration

Is cognitive reserve associated with cognitive function across stroke severity? A longitudinal study among Chinese stroke patients

Correction: Neuroimaging insights into lung disease-related brain changes: from structure to function

Delineation of the cognitive and neuropsychiatric features of Pisa syndrome in dementia with Lewy bodies

MRI-derived global small vessel disease burden serves as a marker of hippocampal sclerosis and clinical stage across the probable Alzheimer’s disease continuum

Neuroimmune dynamics and brain aging: mechanisms and consequences

Vitamin D-linked vulnerability and functional connectivity alterations in the superior frontal gyrus contributing to cognitive impairment in Parkinson’s disease

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study

Singing for memory: neural and cognitive effects of a choral intervention in older adults

Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models induced by chronic administration of D-galactose and D-galactose/AlCl3

LRP1 at the Crossroads of Aβ Clearance and Therapeutic Targeting in Alzheimer's Disease

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Research progress on the interaction between multiple organ-brain axes and perioperative neurocognitive disorders: a narrative review