Frontiers in Aging Neuroscience

Original Research

Accepted on 23 Sep 2025

Peripheral immunity patterns, imaging features, and clinical outcomes in patients with gait impairment and ventriculomegaly on brain MRI

Christian Espinoza-Vinces
Iciar Aviles-Olmos
Jorge M Núñez-Córdoba
Marcos Jiménez-Vázquez
Marta Calvo-Imirizaldu
Genoveva Montoya-Murillo
Gloria Martí-Andrés
Javier Arbizu
María Rosario Luquin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1685288

Original Research

Accepted on 23 Sep 2025

Characterizing Sleep-Related Phenotypes with Patient-Reported Outcomes in Parkinson’s Disease (PRO-PD)

Sandeep Grover
Celina Chand
Mollie Mckenzie Acuff
Joshua Farahnik
Laurie K Mischley

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630150

Original Research

Published on 23 Sep 2025

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

Debo Yun
Yongzhen Luo
Rui Li
Wenyong Li
Chunyou Wan
Qinjiang Huang
Jiang Du
Shiyi Zeng
Guangdong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627353

663 views

Original Research

Published on 23 Sep 2025

Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls

Alberto Gómez-Carballa
Laura Navarro
Nour El Zahraa Mallah
Xabier Bello
Sara Pischedda
Sandra Viz-Lasheras
María José Currás
Isabel Ferreirós-Vidal
Narmeen Mallah
Julián Montoto-Louzao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1622816

254 views

Original Research

Published on 23 Sep 2025

Development and validation of a prognostic scoring system for cognitive decline in adults aged 50 and older in China

Ningjie Zhang
Linglei Meng
Zhendong Qian
Ying Jin
Hua Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1664943

391 views

Original Research

Published on 23 Sep 2025

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

Anton A. Smolentsev
Darya V. Telegina
Nataliya G. Kolosova
Yuri P. Tsentalovich
Olga A. Snytnikova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1648561

838 views

Original Research

Accepted on 22 Sep 2025

Impairment of spatial orientation in the horizontal, but not the vertical plane, by ageing, cognitive decline or chronic peripheral vestibular loss

Johannes Gerb
Vivien Oertle
Burak Onmus
Marianne Dieterich
Thomas Brandt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671562

Mini Review

Accepted on 22 Sep 2025

Biomarkers of Balance and Gait Deficits in FMR1 Premutation Carriers: A Mini-Review

Leila C Moore
Nell Maltman
Jonathan S. Lee-Confer
Megan Kobel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637819

Original Research

Published on 22 Sep 2025

Regional CSF volume quantification using deep learning for comparative analysis of brain atrophy in frontotemporal dementia subtypes

Kyoung Yoon Lim
Soyeon Yoon
Seongbeom Park
Seongmi Kim
Kyoungmin Kim
Jehyun Ahn
Jun Pyo Kim
Hee Jin Kim
Duk L. Na
Sang Won Seo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1631640

531 views

Review

Published on 19 Sep 2025

STING-mediated neuroinflammation: a therapeutic target in neurodegenerative diseases

Haoqin Zhang
Ziyang He
Can Yin
Shiyi Yang
Jianqiao Li
Hong Lin
Guishan Hu
Anguo Wu
Dalian Qin
Guangqiang Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1659216

1,686 views

Systematic Review

Published on 19 Sep 2025

Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic review and meta-analysis of 6655 participants

Zhenzhen Zhao
Jiahui Sun
Youhong Liu
Miao Liu
Di Tong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1620172

919 views

Original Research

Accepted on 18 Sep 2025

Attention-based Transformer-LSTM Architecture for Early Diagnosis and Staging of Early-Stage Parkinson's Disease Using fNIRS Data

Huan Wang
Hujun Wang
Shuyan Qie
Congxiao Wang
Nan Li
Hanming Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1677722

376 views

Original Research

Accepted on 18 Sep 2025

Clinical Validation of a Plasma-Based Antibody-Free LC-MS Method for Identifying CSF Amyloid Positivity in Mild Cognitive Impairment

José Antonio Allué
Leticia Sarasa
Noelia Fandos
Ricardo Gonzalo
Rubén Sabido-Vera
Jorge Loscos
Judith Romero
Adrián Sánchez
Jose Terencio
Jordi A. Matias-Guiu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1681516

391 views

Review

Accepted on 18 Sep 2025

Role of Lipocalin-2 in Amyotrophic Lateral Sclerosis

Zhuoya Wang
Wen Cao
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1672903

333 views

Brief Research Report

Published on 18 Sep 2025

Beyond traditional proxies: the contribution of leisure to cognitive reserve and dementia

Silvia Ottaviani
Luca Tagliafico
Stefania Peruzzo
Marta Ponzano
Alessio Signori
Alessio Nencioni
Fiammetta Monacelli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600798

1,282 views

Original Research

Published on 18 Sep 2025

Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults

Sriya Pallapothu
Roger D. Newman-Norlund
Nicholas Riccardi
Raghav Pallapothu
Pranesh Rajesh Kannan
Leonardo Bonilha
Julius Fridriksson
Chris Rorden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611847

1,122 views