Frontiers in Aging

Review

Accepted on 27 Apr 2026

Gut microbiota-epigenetic interactions in systemic aging: Mechanistic drivers for endocrine and reproductive network remodeling and therapeutic modulation

in Genetics, Genomics and Epigenomics of Aging

CHRISTOPHER BIRIGWA
Qiang Tong
Bing Qu
Teng Zuo
Wenzheng Yuan
Jing Xiong
Jianfei Luo

Frontiers in Aging

211 views

Original Research

Accepted on 27 Apr 2026

Efficacy of Simultaneous Aerobic and Cognitive Training (Activ4Brain) on Physical Fitness and Body Composition in Older Persons

in Interventions in Aging

KAAN AKALP
Hicran Besikçi
Afonso Rainho Mateus
Luis Manuel Rama
José Pedro Ferreira
Maria José Ribeiro
Ana Maria Teixeira

Frontiers in Aging

286 views

Methods

Accepted on 24 Apr 2026

Velocity-Based Resistance Training in Institutionalized Older Adults: Protocol for an Experimental Study with Follow-Up

in Interventions in Aging

Ángel Buendía-Romero
Hector Gutierrez-Reguero
Lucia Romero-Valia
ENRIQUE HIGUERAS LIÉBANA
Mikel Garcia-Aguirre
David Garcia-Albin
Álvaro Rosado Artalejo
Antonio Torres Bertos
Francisco Jose Garcia Garcia
Luis M. Alegre

Frontiers in Aging

312 views

Review

Accepted on 24 Apr 2026

Senescence-Associated Secretory Phenotype: The "Pathogenic" Factor Driving Orthopedic Degenerative Diseases and Its Regulation

in Musculoskeletal Aging

Junxiao Ren
Xiangjin Wang
Xin Zhou
Xiaohong Fan

Frontiers in Aging

285 views

Perspective

Accepted on 23 Apr 2026

Unseen and untreated: Implementing Sarcopenic Obesity Care in Nordic General Practice

in Musculoskeletal Aging

Fereshteh Baygi
Peter Haastrup
Sussi Friis Buhl
Jesper Bo Nielsen
Charlotte Suetta
Michael Skovdal Rathleff
Jens Søndergaard

Frontiers in Aging

268 views

Mini Review

Accepted on 23 Apr 2026

Dietary Pyrroloquinoline Quinone and Spermidine in Healthy Longevity: Targeting the Hallmarks of Aging

in Healthy Longevity

Tomoe Numaguchi
Mai Nakamura
Tomoyo Koshizawa
Nur Syafiqah Mohamad Ishak
Katsuyuki Hashimoto

Frontiers in Aging

545 views

Original Research

Published on 23 Apr 2026

Interviews of community-dwelling older persons in Greece on healthy aging and wellbeing during multiple crises (the HAiG study)

in Healthy Longevity

A. A. Mallidou
E. Zioga
A. Magripi
E. Roditi
F. D. Provida
Th. P. Apostolidi
I. V. Papathanasiou
P. Sourtzi

Frontiers in Aging

doi 10.3389/fragi.2026.1787365

1,299 views

Original Research

Accepted on 22 Apr 2026

Racial Disparities in Pain and Total Knee Arthroplasty Across Knee Osteoarthritis Phenotypes

in Musculoskeletal Aging

Ahmad Alkhatatbeh
Tariq Alkhatatbeh
Jiechen Chen
Hongjiang Chen
Jiankun Xu
Jun Hu

Frontiers in Aging

265 views

Review

Published on 22 Apr 2026

Investigating the research trajectory and future trends in type 2 diabetes mellitus and aging: a bibliometric analysis from 2009 to 2025 based on big data

in Aging, Metabolism and Redox Biology

Tingting Gong
Wei Jiang
Yiman Han
Yang Liu
Wuhui Zhuo
Shengyao Li
Zhipeng Hu
Zixi Zeng
Rensong Yue
Maoyi Yang

Frontiers in Aging

doi 10.3389/fragi.2026.1779773

604 views

Hypothesis and Theory

Accepted on 20 Apr 2026

Studying exercise-induced affect in older adults: how the circumplex model could enhance theoretical and practical advances in the field

in Healthy Longevity

Attila Szabo
Celal Bulgay
Erzsébet Stephens-Sarlós
Róbert Járai
Angela Somogyi
Szilvia Boros
Robert Podstawski
Ferenc Ihász
ROBERTO RUIZ BARQUÍN
Ricardo De La Vega

Frontiers in Aging

266 views

Original Research

Accepted on 20 Apr 2026

Automated generation of personalized trajectories of aging phenotypes with DyViA-GAN

in Interventions in Aging

Saumyadipta S Pyne
Deep Ray
Meghana S Ray

Frontiers in Aging

263 views

Review

Published on 20 Apr 2026

Medication adherence in older adults with chronic diseases: a scoping review of barriers, facilitators, and effective interventions

in Healthy Longevity

Doris Cardona-Arango
Valeria Santacruz-Restrepo
Alejandra Rendón-Montoya
Juliana Madrigal-Cadavid
Alejandra Segura-Cardona
Jorge Iván Estrada-Acevedo

Frontiers in Aging

doi 10.3389/fragi.2026.1642652

1,707 views

Mini Review

Published on 20 Apr 2026

Risk genes in progressive supranuclear palsy (PSP) affect integrity and function of microtubules

in Molecular Mechanisms of Aging

Timothy A. Donlon
Ulrich Müller

Frontiers in Aging

doi 10.3389/fragi.2026.1769377

574 views

Original Research

Published on 17 Apr 2026

The development of the social isolation risk scale (SIRS) to identify risk for social isolation in head and neck cancer survivors

in Aging and Cancer

Allison Marziliano
Nicholas R. Eaton
Mahdia Parker
Maged Ghaly
Diana Schettini
Maureen Balram
Carla Perissinotto
Michael A. Diefenbach

Frontiers in Aging

doi 10.3389/fragi.2026.1805909

385 views

Original Research

Published on 17 Apr 2026

Loneliness within couples coping with cancer: prevalence, associations with physical and mental health, and potential benefits of dyadic exercise

in Aging and Cancer

Kerri Winters-Stone
Sydnee A. Stoyles
Nathan Dieckmann
Alexandra O. Sokolova
Julie N. Graff
Arthur Hung
Shirlene Wang
Karen S. Lyons

Frontiers in Aging

doi 10.3389/fragi.2026.1812899

630 views

Review

Published on 15 Apr 2026

Physical activity interventions to improve physical function in temporarily non-ambulant older persons: a scoping review

in Musculoskeletal Aging

Elma van Garderen
Mandy Visser
Wilco P. Achterberg

Frontiers in Aging

doi 10.3389/fragi.2026.1816647

509 views

Original Research

Published on 15 Apr 2026

The alteration of bile acids and gut microbiota is associated with intestinal barrier dysfunction and inflammaging in human

in Aging, Metabolism and Redox Biology

Yumei Xu
Liang Zhang
Tianci Li
Yanqiu Zhao
Shuo Wang
Junwen Qi
Linsen Shi

Frontiers in Aging

doi 10.3389/fragi.2026.1741360

560 views

Original Research

Published on 14 Apr 2026

Sleep quality and life satisfaction in urban-dwelling solitary Chinese older adults: a study of parallel mediation by depression and cognitive function

in Interventions in Aging

Min Wang
Jingli Yu
Qinshan Huang
Shuxun Chi
Luping Qu

Frontiers in Aging

doi 10.3389/fragi.2026.1780401

401 views

Original Research

Accepted on 13 Apr 2026

Gender-and domain-specific effects of a 6-month multidimensional exercise program on attention and verbal fluency in physically inactive older adults

in Interventions in Aging

Marlene Krumpolt
Anneke Schumacher
Lucas Sannemann
Kerstin Witte

Frontiers in Aging

283 views

Original Research

Published on 10 Apr 2026

Age-related alterations in fatty acid metabolism: a clinical study of erythrocyte and plasma profiles in a population from Brandenburg, Germany

in Aging, Metabolism and Redox Biology

Yingqi Yu
Chaoxuan Wang
Ruirui Wang
Yifang Chen
Zeren Wei
Yanan Xiao
Ulf Elbelt
Anne Pietzner
Karsten H. Weylandt

Frontiers in Aging

doi 10.3389/fragi.2026.1725187

705 views

Original Research

Published on 09 Apr 2026

Impact of moderate treadmill training on cytokine levels in rats: influence of age and sex

in Aging and the Immune System

Renan F. do Espírito-Santo
Youping Zhang
Jin Y. Ro
Joyce T. Da Silva

Frontiers in Aging

doi 10.3389/fragi.2026.1794896

411 views

Review

Published on 09 Apr 2026

The interplay between stroke and hip fractures: a narrative review of mechanisms, risk assessment, and prevention

in Musculoskeletal Aging

Zuzhou Wen
Yun Ye
Junzhao Qiao
Hongqiang Chen

Frontiers in Aging

doi 10.3389/fragi.2026.1780462

487 views

Review

Published on 08 Apr 2026

Research progress on Alzheimer’s disease vaccines: from Aβ-targeted approaches to clinical translation

in Aging and the Immune System

Yan Han
Gaomei Luo
Yanhao Huang
Zhicheng Cai
Wei Su
Xuejun Kuang
Lijuan Huang
Li Wei
Fenghuang Ming
Ziqi He

Frontiers in Aging

doi 10.3389/fragi.2026.1794820

722 views

Original Research

Published on 08 Apr 2026

PCKP versus UPKP for moderate-to-severe osteoporotic vertebral compression fractures: a prospective randomized controlled trial revealing synergistic mechanisms of optimized bone cement distribution and anti-osteoporosis therapy on medium-to-long-term outcomes

in Musculoskeletal Aging

Fuguo Yang
Yuanchao Luo
Kang Chen
Renjian He

Frontiers in Aging

doi 10.3389/fragi.2026.1652951

430 views

775 articles

articles

Gut microbiota-epigenetic interactions in systemic aging: Mechanistic drivers for endocrine and reproductive network remodeling and therapeutic modulation

Efficacy of Simultaneous Aerobic and Cognitive Training (Activ4Brain) on Physical Fitness and Body Composition in Older Persons

Velocity-Based Resistance Training in Institutionalized Older Adults: Protocol for an Experimental Study with Follow-Up

Senescence-Associated Secretory Phenotype: The "Pathogenic" Factor Driving Orthopedic Degenerative Diseases and Its Regulation

Unseen and untreated: Implementing Sarcopenic Obesity Care in Nordic General Practice

Dietary Pyrroloquinoline Quinone and Spermidine in Healthy Longevity: Targeting the Hallmarks of Aging

Interviews of community-dwelling older persons in Greece on healthy aging and wellbeing during multiple crises (the HAiG study)

Racial Disparities in Pain and Total Knee Arthroplasty Across Knee Osteoarthritis Phenotypes

Investigating the research trajectory and future trends in type 2 diabetes mellitus and aging: a bibliometric analysis from 2009 to 2025 based on big data

Studying exercise-induced affect in older adults: how the circumplex model could enhance theoretical and practical advances in the field

Automated generation of personalized trajectories of aging phenotypes with DyViA-GAN

Medication adherence in older adults with chronic diseases: a scoping review of barriers, facilitators, and effective interventions

Risk genes in progressive supranuclear palsy (PSP) affect integrity and function of microtubules

The development of the social isolation risk scale (SIRS) to identify risk for social isolation in head and neck cancer survivors

Loneliness within couples coping with cancer: prevalence, associations with physical and mental health, and potential benefits of dyadic exercise

Physical activity interventions to improve physical function in temporarily non-ambulant older persons: a scoping review

The alteration of bile acids and gut microbiota is associated with intestinal barrier dysfunction and inflammaging in human

Sleep quality and life satisfaction in urban-dwelling solitary Chinese older adults: a study of parallel mediation by depression and cognitive function

Gender-and domain-specific effects of a 6-month multidimensional exercise program on attention and verbal fluency in physically inactive older adults

Age-related alterations in fatty acid metabolism: a clinical study of erythrocyte and plasma profiles in a population from Brandenburg, Germany

Impact of moderate treadmill training on cytokine levels in rats: influence of age and sex

The interplay between stroke and hip fractures: a narrative review of mechanisms, risk assessment, and prevention

Research progress on Alzheimer’s disease vaccines: from Aβ-targeted approaches to clinical translation

PCKP versus UPKP for moderate-to-severe osteoporotic vertebral compression fractures: a prospective randomized controlled trial revealing synergistic mechanisms of optimized bone cement distribution and anti-osteoporosis therapy on medium-to-long-term outcomes