Frontiers in Aging | Genetics, Genomics and Epigenomics of Aging

Original Research

Published on 11 Jul 2024

Molecular mechanisms of genotype-dependent lifespan variation mediated by caloric restriction: insight from wild yeast isolates

in Genetics, Genomics and Epigenomics of Aging

Samantha McLean
Mitchell Lee
Weiqiang Liu
Rohil Hameed
Vikas Anil Gujjala
Xuming Zhou
Matt Kaeberlein
Alaattin Kaya

Frontiers in Aging

doi 10.3389/fragi.2024.1408160

3,033 views
4 citations

Brief Research Report

Published on 30 May 2024

Naïve T-cell decline is a significant contributor to expression changes in ageing blood

in Genetics, Genomics and Epigenomics of Aging

Cameron Fraser
Brady M. Owen

Frontiers in Aging

doi 10.3389/fragi.2024.1389789

2,209 views

Review

Published on 16 May 2024

Selectively advantageous instability in biotic and pre-biotic systems and implications for evolution and aging

in Genetics, Genomics and Epigenomics of Aging

John Tower

Frontiers in Aging

doi 10.3389/fragi.2024.1376060

19,986 views
8 citations

Review

Published on 02 May 2024

Amino acid restriction, aging, and longevity: an update

in Genetics, Genomics and Epigenomics of Aging

S. N. Austad
J. R. Smith
J. M. Hoffman

Frontiers in Aging

doi 10.3389/fragi.2024.1393216

15,213 views
19 citations

Hypothesis and Theory

Published on 08 Apr 2024

Ageing as a two-phase process: theoretical framework

in Genetics, Genomics and Epigenomics of Aging

Flaminia Zane
Claire MacMurray
Clémence Guillermain
Céline Cansell
Nicolas Todd
Michael Rera

Frontiers in Aging

doi 10.3389/fragi.2024.1378351

9,945 views
4 citations

Review

Published on 04 Apr 2024

Exploring juventology: unlocking the secrets of youthspan and longevity programs

in Genetics, Genomics and Epigenomics of Aging

Sebastian Brandhorst
Valter D. Longo

Frontiers in Aging

doi 10.3389/fragi.2024.1379289

6,359 views
1 citation

Review

Published on 26 Mar 2024

Decoding lifespan secrets: the role of the gonad in Caenorhabditis elegans aging

in Genetics, Genomics and Epigenomics of Aging

Andre Pires da Silva
Rhianne Kelleher
Luke Reynoldson

Frontiers in Aging

doi 10.3389/fragi.2024.1380016

4,947 views
4 citations

Review

Published on 08 Mar 2024

Mother’s Curse effects on lifespan and aging

in Genetics, Genomics and Epigenomics of Aging

Suzanne Edmands

Frontiers in Aging

doi 10.3389/fragi.2024.1361396

7,020 views
7 citations

Review

Published on 04 Mar 2024

Disrupting the SKN-1 homeostat: mechanistic insights and phenotypic outcomes

in Genetics, Genomics and Epigenomics of Aging

Chris D. Turner
Carmen M. Ramos
Sean P. Curran

Frontiers in Aging

doi 10.3389/fragi.2024.1369740

5,922 views
17 citations

Original Research

Published on 04 Mar 2024

Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin

in Genetics, Genomics and Epigenomics of Aging

Cassandra Falckenhayn
Agata Bienkowska
Jörn Söhle
Katrin Wegner
Guenter Raddatz
Boris Kristof
Dirk Kuck
Ralf Siegner
Ronny Kaufmann
Julia Korn

Frontiers in Aging

doi 10.3389/fragi.2023.1258184

16,614 views
19 citations

Brief Research Report

Published on 01 Mar 2024

How are APOE4, changes in body weight, and longevity related? Insights from a causal mediation analysis

in Genetics, Genomics and Epigenomics of Aging

Rachel Holmes
Hongzhe Duan
Olivia Bagley
Deqing Wu
Yury Loika
Alexander Kulminski
Anatoliy Yashin
Konstantin Arbeev
Svetlana Ukraintseva

Frontiers in Aging

doi 10.3389/fragi.2024.1359202

5,624 views
6 citations

Review

Published on 15 Feb 2024

MtDNA deletions and aging

in Genetics, Genomics and Epigenomics of Aging

Charlotte Sprason
Trudy Tucker
David Clancy

Frontiers in Aging

doi 10.3389/fragi.2024.1359638

9,077 views
11 citations

Review

Published on 24 Jan 2024

The impact of biomembranes and their dynamics on organismic aging: insights from a fungal aging model

in Genetics, Genomics and Epigenomics of Aging

Heinz D. Osiewacz

Frontiers in Aging

doi 10.3389/fragi.2024.1356697

2,546 views
1 citation

Original Research

Published on 11 Jan 2024

Development of an epigenetic clock to predict visual age progression of human skin

in Genetics, Genomics and Epigenomics of Aging

Agata Bienkowska
Günter Raddatz
Jörn Söhle
Boris Kristof
Henry Völzke
Stefan Gallinat
Frank Lyko
Lars Kaderali
Marc Winnefeld
Elke Grönniger

Frontiers in Aging

doi 10.3389/fragi.2023.1258183

15,413 views
17 citations

Original Research

Published on 11 Jan 2024

A multi-study analysis enables identification of potential microbial features associated with skin aging signs

in Genetics, Genomics and Epigenomics of Aging

Tyler Myers
Amina Bouslimani
Shi Huang
Shalisa T. Hansen
Cécile Clavaud
Anissa Azouaoui
Alban Ott
Audrey Gueniche
Charbel Bouez
Qian Zheng

Frontiers in Aging

doi 10.3389/fragi.2023.1304705

25,565 views
27 citations

Perspective

Published on 12 Dec 2023

Markers and mechanisms of death in Drosophila

in Genetics, Genomics and Epigenomics of Aging

John Tower

Frontiers in Aging

doi 10.3389/fragi.2023.1292040

6,817 views
9 citations

Perspective

Published on 13 Nov 2023

Air pollution, dementia, and lifespan in the socio-economic gradient of aging: perspective on human aging for planning future experimental studies

in Genetics, Genomics and Epigenomics of Aging

Caleb E. Finch

Frontiers in Aging

doi 10.3389/fragi.2023.1273303

4,242 views
7 citations

Original Research

Published on 10 Oct 2023

A cluster of X-linked miRNAs are de-repressed with age in mouse liver and target growth hormone signaling

in Genetics, Genomics and Epigenomics of Aging

Anna P. Petrashen
Yufei Lin
Bianca Kun
Jill A. Kreiling

Frontiers in Aging

doi 10.3389/fragi.2023.1261121

2,083 views
1 citation

Review

Published on 01 Jun 2023

G-quadruplexes and associated proteins in aging and Alzheimer’s disease

in Genetics, Genomics and Epigenomics of Aging

M. J. Vijay Kumar
Rodrigo Morales
Andrey S. Tsvetkov

Frontiers in Aging

doi 10.3389/fragi.2023.1164057

10,277 views
27 citations

Original Research

Published on 31 May 2023

Genetic association of mosaic loss of chromosome Y with prostate cancer in men of European and East Asian ancestries: a Mendelian randomization study

in Genetics, Genomics and Epigenomics of Aging

Takuro Kobayashi
Tsuyoshi Hachiya
Yoshihiro Ikehata
Shigeo Horie

Frontiers in Aging

doi 10.3389/fragi.2023.1176451

6,045 views
15 citations

Review

Published on 24 Apr 2023

Variant biomarker discovery using mass spectrometry-based proteogenomics

in Genetics, Genomics and Epigenomics of Aging

Luke Reilly
Sahba Seddighi
Andrew B. Singleton
Mark R. Cookson
Michael E. Ward
Yue A. Qi

Frontiers in Aging

doi 10.3389/fragi.2023.1191993

7,357 views
9 citations

Original Research

Published on 21 Apr 2023

Antioxidant enzyme and DNA base repair genetic risk scores’ associations with systemic oxidative stress biomarker in pooled cross-sectional studies

in Genetics, Genomics and Epigenomics of Aging

Ziling Mao
Abigail L. H. Gray
Bharat Thyagarajan
Roberd M. Bostick

Frontiers in Aging

doi 10.3389/fragi.2023.1000166

3,141 views

Editorial

Published on 10 Jan 2023

Editorial: Model organisms in aging research: Drosophila melanogaster

in Genetics, Genomics and Epigenomics of Aging

David Clancy
Stanislava Chtarbanova
Susan Broughton

Frontiers in Aging

doi 10.3389/fragi.2022.1118299

4,798 views
11 citations

Editorial

Published on 09 Jan 2023

Editorial: Somatic mutations, genome mosaicism and aging

in Genetics, Genomics and Epigenomics of Aging

Michael A. Lodato
Jan Vijg

Frontiers in Aging

doi 10.3389/fragi.2022.1115408

3,357 views
2 citations

64 articles

articles

Molecular mechanisms of genotype-dependent lifespan variation mediated by caloric restriction: insight from wild yeast isolates

Naïve T-cell decline is a significant contributor to expression changes in ageing blood

Selectively advantageous instability in biotic and pre-biotic systems and implications for evolution and aging

Amino acid restriction, aging, and longevity: an update

Ageing as a two-phase process: theoretical framework

Exploring juventology: unlocking the secrets of youthspan and longevity programs

Decoding lifespan secrets: the role of the gonad in Caenorhabditis elegans aging

Mother’s Curse effects on lifespan and aging

Disrupting the SKN-1 homeostat: mechanistic insights and phenotypic outcomes

Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin

How are APOE4, changes in body weight, and longevity related? Insights from a causal mediation analysis

MtDNA deletions and aging

The impact of biomembranes and their dynamics on organismic aging: insights from a fungal aging model

Development of an epigenetic clock to predict visual age progression of human skin

A multi-study analysis enables identification of potential microbial features associated with skin aging signs

Markers and mechanisms of death in Drosophila

Air pollution, dementia, and lifespan in the socio-economic gradient of aging: perspective on human aging for planning future experimental studies

A cluster of X-linked miRNAs are de-repressed with age in mouse liver and target growth hormone signaling

G-quadruplexes and associated proteins in aging and Alzheimer’s disease

Genetic association of mosaic loss of chromosome Y with prostate cancer in men of European and East Asian ancestries: a Mendelian randomization study

Variant biomarker discovery using mass spectrometry-based proteogenomics

Antioxidant enzyme and DNA base repair genetic risk scores’ associations with systemic oxidative stress biomarker in pooled cross-sectional studies

Editorial: Model organisms in aging research: Drosophila melanogaster

Editorial: Somatic mutations, genome mosaicism and aging