Frontiers in Aging

Original Research

Published on 10 Sep 2021

Anabolic Function Downstream of TOR Controls Trade-offs Between Longevity and Reproduction at the Level of Specific Tissues in C. elegans

Amber C. Howard
Dilawar Mir
Santina Snow
Jordan Horrocks
Hussein Sayed
Zhengxin Ma
Aric N. Rogers

Frontiers in Aging

doi 10.3389/fragi.2021.725068

5,638 views
12 citations

Review

Published on 08 Sep 2021

Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence

Paula R. Barros
Tiago J. Costa
Eliana H. Akamine
Rita C. Tostes

Frontiers in Aging

doi 10.3389/fragi.2021.727604

14,478 views
23 citations

Mini Review

Published on 08 Sep 2021

Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill

Collin Y. Ewald

Frontiers in Aging

doi 10.3389/fragi.2021.741843

23,312 views
22 citations

Review

Published on 31 Aug 2021

ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function

Andrew V. Kuczmarski
Laura M. Welti
Kerrie L. Moreau
Megan M. Wenner

Frontiers in Aging

doi 10.3389/fragi.2021.727416

6,775 views
23 citations

Review

Published on 31 Aug 2021

In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related Disease

Martin Borch Jensen
Adam Marblestone

Frontiers in Aging

doi 10.3389/fragi.2021.714926

22,327 views
6 citations

Review

Published on 27 Aug 2021

The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging

Stephanie A. Fernandes
Constantinos Demetriades

Frontiers in Aging

doi 10.3389/fragi.2021.707372

23,683 views
98 citations

Mini Review

Published on 26 Aug 2021

Aging: What We Can Learn From Elephants

Daniella E. Chusyd
Nicole L. Ackermans
Steven N. Austad
Patrick R. Hof
Michelle M. Mielke
Chet C. Sherwood
David B. Allison

Frontiers in Aging

doi 10.3389/fragi.2021.726714

17,655 views
19 citations

Original Research

Published on 20 Aug 2021

Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults

Stephen N. Crooke
Krista M. Goergen
Inna G. Ovsyannikova
Richard B. Kennedy

Frontiers in Aging

doi 10.3389/fragi.2021.719103

4,117 views
3 citations

Original Research

Published on 13 Aug 2021

Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8+ EMRA T Cells During Type 2 Diabetes

Lauren A. Callender
Elizabeth C. Carroll
Conor Garrod-Ketchley
Johannes Schroth
Jonas Bystrom
Victoria Berryman
Melanie Pattrick
Desiree Campbell-Richards
Gillian A. Hood
Graham A. Hitman

Frontiers in Aging

doi 10.3389/fragi.2021.681428

6,681 views
22 citations

Mini Review

Published on 11 Aug 2021

Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA

Kaoru Sato
Ken-ichi Takayama
Makoto Hashimoto
Satoshi Inoue

Frontiers in Aging

doi 10.3389/fragi.2021.721579

8,638 views
20 citations

Original Research

Published on 10 Aug 2021

Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals

Norihide Jo
Rui Zhang
Hideki Ueno
Takuya Yamamoto
Daniela Weiskopf
Miki Nagao
Shinya Yamanaka
Yoko Hamazaki

Frontiers in Aging

doi 10.3389/fragi.2021.719342

10,632 views
23 citations

Original Research

Published on 09 Aug 2021

Curiosity-Based Interventions Increase Everyday Functioning Score But Not Serum BDNF Levels in a Cohort of Healthy Older Adults

Allison N. Grossberg
Brianne M. Bettcher
Kim A. Gorgens
Aurélie Ledreux

Frontiers in Aging

doi 10.3389/fragi.2021.700838

4,154 views
1 citation

Brief Research Report

Published on 29 Jul 2021

Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

Fedor Galkin
Kirill Kochetov
Polina Mamoshina
Alex Zhavoronkov

Frontiers in Aging

doi 10.3389/fragi.2021.697254

8,544 views
8 citations

Original Research

Published on 27 Jul 2021

Microvascular Sex- and Age- Dependent Phosphodiesterase Expression

Jianjie Wang
Murtaza M. Kazmi
Virginia H. Huxley

Frontiers in Aging

doi 10.3389/fragi.2021.719698

4,469 views
6 citations

Systematic Review

Published on 23 Jul 2021

Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19

Alan Landay
Jenna M. Bartley
Dishary Banerjee
Geneva Hargis
Laura Haynes
Ali Keshavarzian
Chia-Ling Kuo
Oh Sung Kwon
Sheng Li
Shuzhao Li

Frontiers in Aging

doi 10.3389/fragi.2021.695218

9,769 views
5 citations

Original Research

Published on 23 Jul 2021

Metformin Enhances B Cell Function and Antibody Responses of Elderly Individuals With Type-2 Diabetes Mellitus

Daniela Frasca
Alain Diaz
Maria Romero
Bonnie B. Blomberg

Frontiers in Aging

doi 10.3389/fragi.2021.715981

7,851 views
33 citations

Review

Published on 19 Jul 2021

Immunosenescence in Childhood Cancer Survivors and in Elderly: A Comparison and Implication for Risk Stratification

Petra Lázničková
Kamila Bendíčková
Tomáš Kepák
Jan Frič

Frontiers in Aging

doi 10.3389/fragi.2021.708788

6,189 views
8 citations

Review

Published on 16 Jul 2021

Stem Cells in the Myelodysplastic Syndromes

Di Zhan
Christopher Y. Park

Frontiers in Aging

doi 10.3389/fragi.2021.719010

9,710 views
8 citations

Brief Research Report

Published on 15 Jul 2021

Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging

Rebecca L. McIntyre
Mizanur Rahman
Siva A. Vanapalli
Riekelt H. Houtkooper
Georges E. Janssens

Frontiers in Aging

doi 10.3389/fragi.2021.708680

15,545 views
18 citations

Mini Review

Published on 09 Jul 2021

Induction of T Cell Senescence by Cytokine Induced Bystander Activation

Attiya A. Abbas
Arne N. Akbar

Frontiers in Aging

doi 10.3389/fragi.2021.714239

11,971 views
18 citations

Review

Published on 09 Jul 2021

Vaccines and Senior Travellers

Fiona Ecarnot
Stefania Maggi
Jean-Pierre Michel
Nicola Veronese
Andrea Rossanese

Frontiers in Aging

doi 10.3389/fragi.2021.677907

16,783 views
7 citations

Review

Published on 06 Jul 2021

Simple Detection Methods for Senescent Cells: Opportunities and Challenges

Richard G. A. Faragher

Frontiers in Aging

doi 10.3389/fragi.2021.686382

16,124 views
14 citations

Correction

Published on 25 Jun 2021

Corrigendum: Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults

Chris P. Verschoor
Laura Haynes
Graham Pawelec
Mark Loeb
Melissa K. Andrew
George A. Kuchel
Janet E. McElhaney

Frontiers in Aging

doi 10.3389/fragi.2021.718966

1,834 views
2 citations

Mini Review

Published on 24 Jun 2021

Toll-Like Receptors Represent an Important Link for Sex Differences in Cardiovascular Aging and Diseases

Cinthya Echem
Eliana H. Akamine

Frontiers in Aging

doi 10.3389/fragi.2021.709914

4,563 views
8 citations

672 Publications

volumes

Volume 2 - 2021

Anabolic Function Downstream of TOR Controls Trade-offs Between Longevity and Reproduction at the Level of Specific Tissues in C. elegans

Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence

Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill

ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function

In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related Disease

The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging

Aging: What We Can Learn From Elephants

Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults

Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8+ EMRA T Cells During Type 2 Diabetes

Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA

Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals

Curiosity-Based Interventions Increase Everyday Functioning Score But Not Serum BDNF Levels in a Cohort of Healthy Older Adults

Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

Microvascular Sex- and Age- Dependent Phosphodiesterase Expression

Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19

Metformin Enhances B Cell Function and Antibody Responses of Elderly Individuals With Type-2 Diabetes Mellitus

Immunosenescence in Childhood Cancer Survivors and in Elderly: A Comparison and Implication for Risk Stratification

Stem Cells in the Myelodysplastic Syndromes

Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging

Induction of T Cell Senescence by Cytokine Induced Bystander Activation

Vaccines and Senior Travellers

Simple Detection Methods for Senescent Cells: Opportunities and Challenges

Corrigendum: Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults

Toll-Like Receptors Represent an Important Link for Sex Differences in Cardiovascular Aging and Diseases