Frontiers in Aging

Original Research

Published on 09 Aug 2022

Circulating Extracellular Vesicles and Particles Derived From Adipocytes: The Potential Role in Spreading MicroRNAs Associated With Cellular Senescence

Ionara Rodrigues Siqueira
Andressa de Souza Rodrigues
Marina Siqueira Flores
Eduarda Letícia Vieira Cunha
Madeleine Goldberg
Brennan Harmon
Rachael Batabyal
Robert J. Freishtat
Laura Reck Cechinel

Frontiers in Aging

doi 10.3389/fragi.2022.867100

6,090 views
8 citations

Review

Published on 26 Jul 2022

Keeping the beat against time: Mitochondrial fitness in the aging heart

Arielys Mendoza
Jason Karch

Frontiers in Aging

doi 10.3389/fragi.2022.951417

7,869 views
12 citations

Original Research

Published on 22 Jul 2022

Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity

Gary N. Landis
Luke Riggan
Hans S. Bell
William Vu
Tianyi Wang
Ina Wang
Felicia I. Tejawinata
Sebastian Ko
John Tower

Frontiers in Aging

doi 10.3389/fragi.2022.924957

4,044 views
6 citations

Review

Published on 22 Jul 2022

Proteolysis dysfunction in the process of aging and age-related diseases

Natalia Frankowska
Katarzyna Lisowska
Jacek M. Witkowski

Frontiers in Aging

doi 10.3389/fragi.2022.927630

8,440 views
51 citations

Review

Published on 21 Jul 2022

A matter of delicate balance: Loss and gain of Cockayne syndrome proteins in premature aging and cancer

Elena Paccosi
Adayabalam S. Balajee
Luca Proietti-De-Santis

Frontiers in Aging

doi 10.3389/fragi.2022.960662

6,303 views
13 citations

Original Research

Published on 19 Jul 2022

Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms

Rachel Conway
Jack Donato Rockhold
Sara SantaCruz-Calvo
Emelia Zukowski
Gabriella H. Pugh
Hatice Hasturk
Philip A. Kern
Barbara S. Nikolajczyk
Leena P. Bharath

Frontiers in Aging

doi 10.3389/fragi.2022.924003

5,290 views
7 citations

Mini Review

Published on 18 Jul 2022

Functional role of miR-34a in diabetes and frailty

Pasquale Mone
Antonio de Donato
Fahimeh Varzideh
Urna Kansakar
Stanislovas S. Jankauskas
Antonella Pansini
Gaetano Santulli

Frontiers in Aging

doi 10.3389/fragi.2022.949924

4,334 views
20 citations

Review

Published on 18 Jul 2022

Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Adrian Matysek
Sumudu Perera Kimmantudawage
Lei Feng
Andrea B. Maier

Frontiers in Aging

doi 10.3389/fragi.2022.898853

4,509 views
1 citation

Review

Published on 15 Jul 2022

Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration

Yao Tong
Zunyi Zhang
Shusheng Wang

Frontiers in Aging

doi 10.3389/fragi.2022.926627

14,715 views
61 citations

Opinion

Published on 14 Jul 2022

Phosphate Burden and Organ Dysfunction

Nikolay Mironov
Azeddine Atfi
Mohammed S. Razzaque

Frontiers in Aging

doi 10.3389/fragi.2022.890985

5,960 views
8 citations

Review

Published on 12 Jul 2022

Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations

Gérald J. Prud’homme
Mervé Kurt
Qinghua Wang

Frontiers in Aging

doi 10.3389/fragi.2022.931331

91,204 views
182 citations

Original Research

Published on 11 Jul 2022

Auxin-Inducible Degron System Reveals Temporal-Spatial Roles of HSF-1 and Its Transcriptional Program in Lifespan Assurance

Allison C. Morphis
Stacey L. Edwards
Purevsuren Erdenebat
Lalit Kumar
Jian Li

Frontiers in Aging

doi 10.3389/fragi.2022.899744

5,864 views
4 citations

Review

Published on 08 Jul 2022

HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network

Maria I. Lazaro-Pena
Zachary C. Ward
Sifan Yang
Alexandra Strohm
Alyssa K. Merrill
Celia A. Soto
Andrew V. Samuelson

Frontiers in Aging

doi 10.3389/fragi.2022.861686

8,463 views
19 citations

Review

Published on 07 Jul 2022

Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease

Tinka Vidović
Collin Y. Ewald

Frontiers in Aging

doi 10.3389/fragi.2022.935220

13,346 views
17 citations

Original Research

Published on 04 Jul 2022

Musculoskeletal Biomarkers Response to Exercise in Older Adults

Eduardo L. Abreu
Amy Vance
An-Lin Cheng
Marco Brotto

Frontiers in Aging

doi 10.3389/fragi.2022.867137

6,862 views
6 citations

Original Research

Published on 30 Jun 2022

Prevalence and Correlates of Motoric Cognitive Risk Syndrome in Chinese Community-Dwelling Older Adults

Anying Bai
Weihao Xu
Zhanyi Lin

Frontiers in Aging

doi 10.3389/fragi.2022.895138

7,622 views
14 citations

Review

Published on 22 Jun 2022

C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration

Francisco José Naranjo-Galindo
Ruixue Ai
Evandro Fei Fang
Hilde Loge Nilsen
Tanima SenGupta

Frontiers in Aging

doi 10.3389/fragi.2022.916118

13,908 views
17 citations

Systematic Review

Published on 22 Jun 2022

A Systematic Review of the Effects of Second-Eye Cataract Surgery on Motor Function

William E. A. Sheppard
Dane McCarrick
Richard M. Wilkie
Rigmor C. Baraas
Rachel O. Coats

Frontiers in Aging

doi 10.3389/fragi.2022.866823

5,189 views
3 citations

Original Research

Published on 21 Jun 2022

The Role of GCN2 Kinase in Mediating the Effects of Amino Acids on Longevity and Feeding Behaviour in Drosophila

Anchal Srivastava
Jiongming Lu
Dennis Said Gadalla
Oliver Hendrich
Sebastian Grönke
Linda Partridge

Frontiers in Aging

doi 10.3389/fragi.2022.944466

7,911 views
21 citations

Editorial

Published on 20 Jun 2022

Editorial: Molecular Role of Lipids in Aging

Dorota Skowronska-Krawczyk
Priyanka Narayan
Peter Tessarz

Frontiers in Aging

doi 10.3389/fragi.2022.946884

3,665 views
1 citation

Review

Published on 16 Jun 2022

Friend or Foe? Defining the Role of Glutamate in Aging and Alzheimer’s Disease

MaKayla F. Cox
Erin R. Hascup
Andrzej Bartke
Kevin N. Hascup

Frontiers in Aging

doi 10.3389/fragi.2022.929474

14,725 views
66 citations

Review

Published on 14 Jun 2022

Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs

Carolin Thomas
Lia Wurzer
Ernst Malle
Michael Ristow
Corina T. Madreiter-Sokolowski

Frontiers in Aging

doi 10.3389/fragi.2022.905261

10,777 views
12 citations

Review

Published on 02 Jun 2022

The Intestine as a Lifespan- and Proteostasis-Promoting Signaling Tissue

Francesca Hodge
Viktoria Bajuszova
Patricija van Oosten-Hawle

Frontiers in Aging

doi 10.3389/fragi.2022.897741

6,660 views
27 citations

Review

Published on 01 Jun 2022

Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models

Nurcan Inci
Dilanur Kamali
Erdogan Oguzhan Akyildiz
Eda Tahir Turanli
Perinur Bozaykut

Frontiers in Aging

doi 10.3389/fragi.2022.828058

7,987 views
9 citations

129 Publications

volumes

Circulating Extracellular Vesicles and Particles Derived From Adipocytes: The Potential Role in Spreading MicroRNAs Associated With Cellular Senescence

Keeping the beat against time: Mitochondrial fitness in the aging heart

Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity

Proteolysis dysfunction in the process of aging and age-related diseases

A matter of delicate balance: Loss and gain of Cockayne syndrome proteins in premature aging and cancer

Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms

Functional role of miR-34a in diabetes and frailty

Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration

Phosphate Burden and Organ Dysfunction

Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations

Auxin-Inducible Degron System Reveals Temporal-Spatial Roles of HSF-1 and Its Transcriptional Program in Lifespan Assurance

HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network

Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease

Musculoskeletal Biomarkers Response to Exercise in Older Adults

Prevalence and Correlates of Motoric Cognitive Risk Syndrome in Chinese Community-Dwelling Older Adults

C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration

A Systematic Review of the Effects of Second-Eye Cataract Surgery on Motor Function

The Role of GCN2 Kinase in Mediating the Effects of Amino Acids on Longevity and Feeding Behaviour in Drosophila

Editorial: Molecular Role of Lipids in Aging

Friend or Foe? Defining the Role of Glutamate in Aging and Alzheimer’s Disease

Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs

The Intestine as a Lifespan- and Proteostasis-Promoting Signaling Tissue

Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models