Frontiers in Aging

Original Research

Published on 11 Dec 2025

Self-reported, functional, and objective health and sociodemographic characteristics among older adults in Kenya: findings from the pilot longitudinal study of health and ageing in Kenya (LOSHAK)

Eunice Muthoni Mwangi
James Orwa
Roselyter Monchari Riang’a
Niranjani Nagarajan
Felix Agoi
Patrick N. Mwangala
Alden L. Gross
Jean N. Ikanga
Kenneth M. Langa
Edward Miguel

Frontiers in Aging

doi 10.3389/fragi.2025.1693701

5,721 views

Original Research

Published on 11 Dec 2025

Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina

Marco Santillán Pazmiño
Paula Constanza Arriola Benitez
Maria Florencia Fernandez
Silvina Yantorno
Valeria Descalzi
Franco Daniel Tarditti
María Lucia Novellis
Juan Cruz Fasolo
Martín Rumbo
Stefan Günther Tullius

Frontiers in Aging

doi 10.3389/fragi.2025.1729048

1,076 views

Editorial

Published on 11 Dec 2025

Editorial: (Un)healthy lifestyles, aging, and type 2 diabetes

Pedro Duarte-Mendes
Fernanda M. Silva
Ana M. Teixeira

Frontiers in Aging

doi 10.3389/fragi.2025.1696856

879 views

Original Research

Published on 10 Dec 2025

Impact of multicomponent home-based exercise on fear of falling in older people with a history of falls: insights from the GAITCARE project

Elisabet Huertas-Hoyas
Marta Neira Álvarez
Agustín Curiel-Regueros
Luisa Ruiz-Ruiz
Rafael García-Molina
Cristina Alonso Bouzón
Eva Rincon-Herrera
Sara García De Villa
Antonio R. Jiménez-Ruiz

Frontiers in Aging

doi 10.3389/fragi.2025.1698917

858 views

Editorial

Published on 09 Dec 2025

Editorial: Insights in aging, metabolism and redox biology: 2024

Ruben K. Dagda
Jianhua Zhang

Frontiers in Aging

doi 10.3389/fragi.2025.1750125

1,377 views

Mini Review

Published on 05 Dec 2025

Toward precision longevity: aging interventions in the single-cell atlas era

Jason B. Chen
Miranda C. Wang
Shangyu Gong
Hongjie Li

Frontiers in Aging

doi 10.3389/fragi.2025.1674112

2,659 views

Review

Published on 04 Dec 2025

The intersection of TREX1, cGAS, STING and the DNA damage theory of aging

Kate M. Jones
Samuel D. Chauvin
Jonathan J. Miner

Frontiers in Aging

doi 10.3389/fragi.2025.1720372

2,152 views

Brief Research Report

Published on 01 Dec 2025

Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study

Michael Sayer
Ding Quan Ng
Julia Trudeau
Raymond J. Chan
Munjal M. Acharya
Kord Kober
Alexandre Chan

Frontiers in Aging

doi 10.3389/fragi.2025.1667638

1,786 views

Brief Research Report

Published on 27 Nov 2025

Bone mineral density and turnover response to GLP-1 receptor agonists in older adults with overweight/obesity and prediabetes/type 2 diabetes: a 20-week pilot trial post hoc analysis

Lauren Dinkla
Kristen M. Beavers
Ronna Robbins
Dela Akpalu
Sarah J. Wherry
Gary Miller
Daniel P. Beavers
Sara Espinoza
Jonathan Trejo
Allison Stepanenko

Frontiers in Aging

doi 10.3389/fragi.2025.1691007

2,699 views

Review

Published on 27 Nov 2025

Single-cell multi-omics for precision cardiovascular and longevity medicine: from methods to clinical translation

Thiago Guimarães Osório
Estefania Pavesi
Khalil Abou El-Ardat
Needa Qureshi
Leanne Cassidy
Terrence Lee St. John
Nicole Sirotin
Bartlomiej Piechowski-Jozwiak

Frontiers in Aging

doi 10.3389/fragi.2025.1656727

7,652 views

Original Research

Published on 27 Nov 2025

Celastrol attenuates diabetic kidney disease progression by repressing senescence of renal tubular epithelial cells

Yajun Zhang
Zewei Sun
Weixue Meng
Siqi Lei
Jingyong Sun
Yixuan Tang
Xiaodong Mu

Frontiers in Aging

doi 10.3389/fragi.2025.1657947

1,438 views

Original Research

Published on 26 Nov 2025

Lived experiences and informed behavior change among premenopausal women in a group exercise trial: a qualitative inquiry

Jaclyn Inel Hadfield
Ryan Hulteen
Jenna Parsons
Heather Allaway

Frontiers in Aging

doi 10.3389/fragi.2025.1712679

1,028 views

Mini Review

Published on 25 Nov 2025

Natural strategies to optimize estrogen levels in aging women: mini review

Olena Bolgova
Inna Shypilova
Volodymyr Mavrych

Frontiers in Aging

doi 10.3389/fragi.2025.1706117

9,544 views

Brief Research Report

Published on 25 Nov 2025

A community-based, medical student-led walking and education program was associated with a reduction in frailty levels among adults with elevated frailty

Myles W. O’Brien
Taylor M. Wilson
Muhammad Cheema
Zainab Zafar
Minji Choi
Madeline E. Shivgulam
Olga Theou

Frontiers in Aging

doi 10.3389/fragi.2025.1690493

6,673 views

Original Research

Accepted on 21 Nov 2025

Emerging PFAS Contaminants PFNA and PFSA Amplify Epigenetic Aging: Sex-and Age-Stratified Risks in an Aging Population

Ya-Qian Xu
Chongyu Ding
Hui Zhang
Yulu Gong
Darong Hao
Xuetong Zhao
Kai Li

Frontiers in Aging

920 views

Review

Published on 21 Nov 2025

The gut–brain axis in Alzheimer’s disease: how gut microbiota modulate microglial function

Huan Wang
Feifan Yang
Zhejianyi Gao
Zedong Cheng
Xicai Liang

Frontiers in Aging

doi 10.3389/fragi.2025.1704047

2,839 views
1 citation

Original Research

Published on 20 Nov 2025

Muscle quality responses to short-term resistance training volume in older adults: an exploratory clinical trial

Kevan S. Knowles
Logan A. Banks
Vanessa C. Cabrera
Wyatt Wilkinson
Adrian J. Pantoja
Isabella G. Thomas
Emily J. Parsowith
Jonathan P. Beausejour
Grant Norte
Jeffrey R. Stout

Frontiers in Aging

doi 10.3389/fragi.2025.1670709

2,097 views

Hypothesis and Theory

Published on 20 Nov 2025

Estimation of biological aging based on T-cell differentiation trajectories: emerging and future avenues

Aarav M. Bhasin
Ishaan K. Marwaha
Lahiri S. Nooka

Frontiers in Aging

doi 10.3389/fragi.2025.1684051

1,614 views

Brief Research Report

Published on 19 Nov 2025

Effect of maximal mental effort during elastic band training on neuromuscular adaptations in older women

Lacey Harper
Kayla Anderson
William Reed
Kaden Buford
Anna Acosta
Jacob Grazer
Robert Buresh
Tim Martin
Garrett Hester

Frontiers in Aging

doi 10.3389/fragi.2025.1662126

1,260 views

Original Research

Published on 19 Nov 2025

The association between anserine bursa pain and fall susceptibility: a prospective analysis of the osteoarthritis initiative

Fugui Wang
Jianhua Xiao
Zhi Song
Chao Zhang
Zhengyuan Zhu

Frontiers in Aging

doi 10.3389/fragi.2025.1666627

877 views

Correction

Published on 18 Nov 2025

Correction: Influence of circadian rhythm on the determination of the IMMune Age indeX (IMMAX)

Sina Trebing
Peter Bröde
Maren Claus
Carsten Watzl

Frontiers in Aging

doi 10.3389/fragi.2025.1743195

599 views

Editorial

Published on 14 Nov 2025

Editorial: Aging epigenome and longevity

Sandeep Kumar Singh
Burkhard Poeggeler

Frontiers in Aging

doi 10.3389/fragi.2025.1739913

956 views

Editorial

Published on 13 Nov 2025

Editorial: Insights into falls efficacy and fear of falling

Shawn Leng-Hsien Soh
William R. Young
Tianma Xu

Frontiers in Aging

doi 10.3389/fragi.2025.1644435

994 views

Review

Published on 12 Nov 2025

Advanced immunology in aging population: unveiling the complexities of vaccine responsiveness

Yan Han
Yanhao Huang
Yuanyu Zhou
Wanke He
Gaomei Luo
Liu Yang
Yanbin Chen
Yiqi Zhu
Wei Jiang
Chanchan Xiao

Frontiers in Aging

doi 10.3389/fragi.2025.1682763

1,960 views

682 Publications

volumes

Volume 6 - 2025

Self-reported, functional, and objective health and sociodemographic characteristics among older adults in Kenya: findings from the pilot longitudinal study of health and ageing in Kenya (LOSHAK)

Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina

Editorial: (Un)healthy lifestyles, aging, and type 2 diabetes

Impact of multicomponent home-based exercise on fear of falling in older people with a history of falls: insights from the GAITCARE project

Editorial: Insights in aging, metabolism and redox biology: 2024

Toward precision longevity: aging interventions in the single-cell atlas era

The intersection of TREX1, cGAS, STING and the DNA damage theory of aging

Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study

Bone mineral density and turnover response to GLP-1 receptor agonists in older adults with overweight/obesity and prediabetes/type 2 diabetes: a 20-week pilot trial post hoc analysis

Single-cell multi-omics for precision cardiovascular and longevity medicine: from methods to clinical translation

Celastrol attenuates diabetic kidney disease progression by repressing senescence of renal tubular epithelial cells

Lived experiences and informed behavior change among premenopausal women in a group exercise trial: a qualitative inquiry

Natural strategies to optimize estrogen levels in aging women: mini review

A community-based, medical student-led walking and education program was associated with a reduction in frailty levels among adults with elevated frailty

Emerging PFAS Contaminants PFNA and PFSA Amplify Epigenetic Aging: Sex-and Age-Stratified Risks in an Aging Population

The gut–brain axis in Alzheimer’s disease: how gut microbiota modulate microglial function

Muscle quality responses to short-term resistance training volume in older adults: an exploratory clinical trial

Estimation of biological aging based on T-cell differentiation trajectories: emerging and future avenues

Effect of maximal mental effort during elastic band training on neuromuscular adaptations in older women

The association between anserine bursa pain and fall susceptibility: a prospective analysis of the osteoarthritis initiative

Correction: Influence of circadian rhythm on the determination of the IMMune Age indeX (IMMAX)

Editorial: Aging epigenome and longevity

Editorial: Insights into falls efficacy and fear of falling

Advanced immunology in aging population: unveiling the complexities of vaccine responsiveness