Frontiers in Behavioral Neuroscience | Pathological Conditions

Original Research

Published on 17 Dec 2025

Traditional and non-traditional behavioral tests demonstrate the attenuation of cognitive deficits by therapeutic hypothermia in a rat model of neonatal hypoxic–ischemic encephalopathy

in Pathological Conditions

Angela Saadat
Cortney Kaszowski
Haree Pallera
Frank Lattanzio
Richard A. Britten
Asna Sulaiman
Stephanie Newman
Alireza Hosseini
Tushar Shah

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1695435

119 views

Original Research

Accepted on 15 Dec 2025

Customized SAM-Med3D with Multi-view Adapter and T2-FLAIR Mismatch Features for Glioma IDH Genotyping and Grading

in Pathological Conditions

Xinyu Li
Hui Li
Yunyi Hu
Jingjing Zhang
Lanlan Wang
Xinran Yang

Frontiers in Behavioral Neuroscience

Original Research

Accepted on 09 Dec 2025

Supportive Enriched Environment Improves Recovery from Persistent Motor and Cognitive Impairments After Severe Traumatic Brain Injury

in Pathological Conditions

Margaret Anne Lovier
Michele Kyle
Karen Hughes
Li-Ru ZHAO

Frontiers in Behavioral Neuroscience

201 views

Methods

Published on 05 Dec 2025

Automated thermal gradient test for unprovoked assessment of nociceptive preference in rodents

in Pathological Conditions

Thomas Deakin
Shoupeng Wei
Yao Wang
Raina E. Rhoades
Tommy S. Tillman
Pei Tang
Yan Xu

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1709160

480 views

Correction

Published on 01 Dec 2025

Correction: Generalized tonic-clonic seizures as the initial symptom of late-onset Krabbe disease: a Case Report

in Pathological Conditions

Sifen Xie
Zuying Kuang
Mengqiu Pan
Kanghua Zhang
Jinlong Ye
Bo Li
Sheng Luo
Zhanhang Wang

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1741000

436 views

Original Research

Published on 26 Nov 2025

Early-life pain alters excitability of corticotropin-releasing factor-expressing neurons in the central amygdala and stress-induced hypersensitivity during adolescence

in Pathological Conditions

Megan Tomasch
Emma Naess
Skyler McComas
Michael A. Burman

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1653346

1,017 views

Original Research

Published on 12 Nov 2025

Transdiagnostic relevance of subjective cognitive complaints: a validation and population-based study using two Canadian scales (SSTICS and MoCA) in the UAE

in Pathological Conditions

Fadwa Al Mugaddam
Karim Abdel-Aziz
Syed Fahad Javaid
Javaid Nauman
Iffat ElBarazi
Emmanuel Stip

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1677371

885 views

Case Report

Published on 06 Nov 2025

Generalized tonic-clonic seizures as the initial symptom of late-onset Krabbe disease: a Case Report

in Pathological Conditions

Sifen Xie
Zuying Kuang
Mengqiu Pan
Kanghua Zhang
Jinlong Ye
Bo Li
Sheng Luo
Zhanhang Wang

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1564676

1,055 views

Opinion

Published on 23 Sep 2025

Positioning berries in nutritional psychiatry: potential for prevention and co-therapy in mental health

in Pathological Conditions

Rafael Fernández-Demeneghi
Marilú Domínguez-Pantoja
Alma Gabriela Martínez-Moreno
Isidro Vargas-Moreno
Rodrigo Ramirez-Rodriguez

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1622242

2,698 views

Original Research

Published on 08 Sep 2025

Sex differences in outcomes of first episode psychosis: results from an early intervention service

in Pathological Conditions

Ilaria Domenicano
Alice Onofrio
Martina Citton
Ludovica Vecchioni
Domenico De Donatis
Raffaella Bertelli
Franca Emanuelli
Luigi Grassi
Maria Ferrara

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1642460

2,374 views
1 citation

Original Research

Published on 12 Aug 2025

Triamcinolone-loaded nanocarriers: a novel strategy to mitigate cognitive and emotional sequelae induced by traumatic brain injury via modulation of oxidative stress

in Pathological Conditions

Aída Marcotti
Sofía De la Fuente
María Lina Formica
Agustín Jorge Montivero
Martina Ramires
Verónica Leonor Romero
María Florencia Constantin
María Jazmín Silvero
María Cecilia Becerra
Gastón Diego Calfa

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1638417

2,542 views

Review

Published on 31 Jul 2025

Neural mechanisms of maladaptive risk decision-making across psychiatric disorders

in Pathological Conditions

Cancan Lin
Yuhui Wang
Wenjie Xia
Defu Zhang
Xvbo Wang
Yue Wang
Yuxin Du
Hao Yu
Shanling Ji

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1637582

3,584 views

Original Research

Published on 29 Jul 2025

Glutamatergic lateral habenula neurons modulate consolidation of associative memories

in Pathological Conditions

Snigdha Srivastava
I-Ching Wang
Mikhail Y. Kochukov
Jessica L. Swanson
Mauro Costa-Mattioli
Benjamin R. Arenkiel

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1646689

2,906 views

Original Research

Published on 25 Jul 2025

The protracted neurotoxic consequences in mice of developmental exposures to inhaled iron nanoparticles alone or in combination with SO2

in Pathological Conditions

Deborah A. Cory-Slechta
Elena Marvin
Kevin Welle
Gunter Oberdörster
Marissa Sobolewski

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1544974

1,415 views

Brief Research Report

Published on 22 Jul 2025

Multi-domain destructuring in the early phases of psychosis: a multicentric phenomenological and psychometric case-control study

in Pathological Conditions

Ottone Baccaredda Boy
Giuseppe Pierpaolo Merola
Andrea Patti
Bernardo Bozza
Dario Flaccomio
Marco Faldi
Giulia Pitt
Luca Papini
Vincenzo Pecoraro
Ilaria Noschese

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1614730

1,910 views

Original Research

Published on 06 Jun 2025

Characterization of alterations in spontaneous behaviors in a rat model of neuropathic pain - new outcome measures for pain evaluation?

in Pathological Conditions

Annamária Liptáková
M. J. Castelhano-Carlos
Juliana Fiúza-Fernandes
Nuno Sousa
Michelle Roche
David P. Finn
Hugo Leite-Almeida

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1550476

2,801 views

Mini Review

Published on 07 Apr 2025

Current limitations in technology-based cognitive assessment for severe mental illnesses: a focus on feasibility, reliability, and ecological validity

in Pathological Conditions

Edoardo Caporusso
Antonio Melillo
Andrea Perrottelli
Luigi Giuliani
Francesco Flavio Marzocchi
Pasquale Pezzella
Giulia Maria Giordano

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1543005

4,492 views
1 citation

Opinion

Published on 06 Feb 2025

A critical opinion on adult endogenous neurogenesis as a brain repair mechanism after traumatic brain injury

in Pathological Conditions

Andrea Aguilar-Arredondo
Angélica Zepeda

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1543122

2,572 views

Original Research

Published on 05 Feb 2025

Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury

in Pathological Conditions

Hannah C. Downing
Ashley B. Glover
Jessica E. Gebhardt
Katherine L. Thompson
Kathryn E. Saatman

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1523969

2,700 views

Original Research

Published on 17 Dec 2024

Selective deletion of Tsc1 from mouse cerebellar Purkinje neurons drives sex-specific behavioral impairments linked to autism

in Pathological Conditions

Ryan J. Lawson
Nicholas J. Lipovsek
Samuel P. Brown
Achintya K. Jena
Joanna J. Osko
Joseph L. Ransdell

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2024.1474066

2,512 views
4 citations

Original Research

Published on 23 Oct 2024

Distinct acute stressors produce different intensity of anxiety-like behavior and differential glutamate release in zebrafish brain

in Pathological Conditions

Milena Letícia Martins
Emerson Feio Pinheiro
Geovanna Ayami Saito
Caroline Araújo Costa De Lima
Luana Ketlen Reis Leão
Evander de Jesus Oliveira Batista
Adelaide da Conceição Fonseca Passos
Amauri Gouveia
Karen Renata Herculano Matos Oliveira
Anderson Manoel Herculano

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2024.1464992

3,123 views
9 citations

Review

Published on 08 Oct 2024

Traumatic brain injuries: a neuropsychological review

in Pathological Conditions

Aldrich Chan
Jason Ouyang
Kristina Nguyen
Aaliyah Jones
Sophia Basso
Ryan Karasik

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2024.1326115

31,007 views
9 citations

Brief Research Report

Published on 12 Sep 2024

Parkinson’s LRRK2-G2019S risk gene mutation drives sex-specific behavioral and cellular adaptations to chronic variable stress

in Pathological Conditions

Christopher A. Guevara
Kumayl Alloo
Swati Gupta
Romario Thomas
Pamela del Valle
Alexandra R. Magee
Deanna L. Benson
George W. Huntley

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2024.1445184

2,673 views
2 citations

Brief Research Report

Published on 19 Aug 2024

Cerebrospinal fluid characteristics of patients presenting for evaluation of pediatric acute-neuropsychiatric syndrome

in Pathological Conditions

Rajdeep Pooni
Wynne Zheng
Meiqian Ma
Melissa Silverman
Yuhuan Xie
Bahare Farhadian
Margo Thienemann
Elizabeth Mellins
Jennifer Frankovich

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2024.1342486

4,580 views
3 citations