Frontiers in Bioengineering and Biotechnology

Original Research

Accepted on 04 Jul 2025

PLGA NANOPARTICLES FOR CAPSAICIN DELIVERY: ENHANCED ENCAPSULATION EFFICIENCY AND PRO-APOPTOTIC ACTIVITY IN HEPG2 CELLS

in Nanobiotechnology

Chiara Mulè
Tania Mariastella Caputo
Antonio Montefusco
Antonio Massimiliano Romanelli
Ivana Caputo
Gaetana Paolella
Anna Aliberti
Andrea Cusano

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1617022

Original Research

Accepted on 04 Jul 2025

Adaptive Responses of Gordonia alkanivorans IEGM 1277 to the Action of Meloxicam and its Efficient Biodegradation

in Bioprocess Engineering

Semyon Tyan
Nadezhda Kostrikina
Vladimir Sorokin
Andrey Mulyukin
Irina Ivshina

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1603975

Original Research

Accepted on 04 Jul 2025

Enhanced Transdermal Delivery of Lidocaine Cream via Ultrasound and Microneedle Rollers

in Nanobiotechnology

Jiaxiao Sun
Yang Yang
Juanjuan Zheng
Hao Liang
Feng Yan
Wensheng Zhang
Wenqin Xie

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1612145

Review

Accepted on 04 Jul 2025

Bridging the Gap: The Role of 3D Cell Cultures in Mimicking Tumor Microenvironment for Enhanced Drug Testing Accuracy

in Organoids and Organ-On-A-Chip

Yan Zhou
Fei-Yuan Yu
Min Guo
Yao Tang
Qian Xu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1498141

118 views

Review

Accepted on 04 Jul 2025

Nanomaterials Engineered for Photothermal Therapy in Neural Tumors and Neurodegenerative Diseases: Biomaterial Design, Clinical Mechanisms and Applications

in Nanobiotechnology

Hanjing Zhu
Wei Yang
Yijun Suo
Ye Liu
Xinyi Zhan
Jun Zhou
Zhiying Chen
Xiangbing Wu
Xiaoping Yin
Bing Bao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1631627

Original Research

Published on 04 Jul 2025

A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions

in Synthetic Biology

Wataru Kitagawa
Kensuke Igarashi
Ryo Nagasawa
Shigeyuki Kakizawa
Mizuki Horino
Kosuke Fujishima
Toshiaki Fukui
Souichiro Kato

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1595440

398 views

Original Research

Published on 04 Jul 2025

Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes: a proof of concept

in Cell and Gene Therapy

Samuel Lukas Schneider
Abiram Gopalakrishnan
Misha Alexander Teale
Regine Eibl

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611703

581 views

Original Research

Accepted on 03 Jul 2025

Development of a One-Pot RPA-Cas12a/13a Assay for Simultaneous Detection of HPV16 and HPV18

in Biosensors and Biomolecular Electronics

Qiujie Yu
Hongzhi Luo
Xiaoxue Huang
Xiaohua An
Yan Wang
Huasu Chen
Jianhuang Rong
Yafei Zhang
Qianhao Huang
Yudi Rao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1608301

137 views

Original Research

Published on 03 Jul 2025

Preparation and characterization of a GSH-responsive drug-loaded polymer nanoparticle/silk fibroin composite hydrogel

in Biomaterials

Yanjiu Li
Rong Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643800

309 views

Original Research

Published on 03 Jul 2025

Biomechanical effects of orthodontic tooth movement on edentulous alveolar bone: a finite element analysis

in Biomechanics

Xiaoxu Wang
Jiaojiao Xue
Xiaoting Wang
Mingyue Fan

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1625027

334 views

Original Research

Published on 03 Jul 2025

Impact of aortic morphology on VA-ECMO performance: a combined statistical shape modeling and CFD approach

in Biomechanics

Marilena Mazzoli
Emanuele Gasparotti
Emanuele Vignali
Dorela Haxhiademi
Simona Celi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1620897

407 views

Original Research

Accepted on 02 Jul 2025

Anion Exchange Chromatography-Based Purification of Plant-derived Nanovesicles from Brassica oleracea L.: Molecular Profiling and Bioactivity in Human Cells

in Nanobiotechnology

Clarissa Zanotti
Simona Arena
Sabrina De Pascale
Valentina Ciaravolo
Rosalia Ferracane
Antonio Dario Troise
Chiara Pontecorvi
Francesca Pacello
Chiara Niespolo
Angelo Gismondi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1617478

136 views

Review

Accepted on 02 Jul 2025

Advances in Hyaluronic Acid Hydrogel for Meniscus Repair

in Biomaterials

Guangxin Wang
Xiao Jun Liu
Xin-an Zhang
Mingjie Hu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1639034

180 views

Systematic Review

Accepted on 02 Jul 2025

No Difference between CT-and MRI-based Patient-specific Instrumentation for Total Knee Arthroplasty: An Updated Systematic Review and Meta-analysis

in Biomaterials

Long Shao
Xiang-Dong Wu
Yuhao Liu
Xing Wang
Chun Yan Li
Kun Tao
Shicheng Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1624600

Original Research

Accepted on 02 Jul 2025

A Rapid-Release Pure Iodine Coating on Titanium Implants to Mitigate Acute Periprosthetic Infections

in Biomaterials

Xiu Yang
Yong-Quan Zhang
Jie Liang
Qing-Quan Chen
Xiao-Li Huang
Wan-Ming Wang
Jin-shui Chen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1590411

151 views

Original Research

Accepted on 02 Jul 2025

Neural-Enhanced Motion-to-EMG: Refining Simulated Muscle Activity from Musculoskeletal Models using a Seq2Seq Approach

in Biomechanics

Tatsuya Teramae
Takamitsu Matsubara
Tomoyuki Noda
Jun Morimoto

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611414

112 views