Frontiers in Bioengineering and Biotechnology

Review

Published on 21 Jan 2026

Research advances in cryopreserved preparations of mesenchymal stem cells: technical innovations, application challenges, and quality control

in Tissue Engineering and Regenerative Medicine

Yuhao Wang
Kexin Yang
Shengmeng Yuan
Fangjun Huo
Chao Yang
Weidong Tian

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1717539

876 views

Brief Research Report

Published on 21 Jan 2026

A hybrid vocal fold phonatory platform for pediatric phonation modeling

in Biofabrication

Leila Donyaparastlivari
Rishi Kuriakose
Mohaddeseh Mohammadi
Ayda Pourmostafa
Daniel Li
Scott L. Thomson
Chen Shen
Amir K. Miri

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1699406

855 views

Correction

Published on 21 Jan 2026

Correction: GBR assisted in situ Onlay bone grafting for the posterior mandible horizontal ridge augmentation: a case report and literature review

in Tissue Engineering and Regenerative Medicine

Mucong Li
Xiuyu Liu
Jing Zhou
Jiaqian You
Sheng Chen
Jian Feng
Xuyan Wei
Hanchi Wang
Yanmin Zhou

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1784687

452 views

Review

Published on 20 Jan 2026

Development of a 3D tumor model based on decellularized matrix using high-throughput approaches

in Tissue Engineering and Regenerative Medicine

Homayoon Siahmansouri
Daniela Fenoglio
Gilberto Filaci
Maddalena Mastrogiacomo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1690844

993 views

Systematic Review

Published on 20 Jan 2026

Type VIII collagen: advances in matrix biology and translational promise

in Tissue Engineering and Regenerative Medicine

Haiyan Shi
Yufeng Yu
Kaixuan Guo
Rongli He

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1732988

1,286 views

Original Research

Published on 20 Jan 2026

3D-printed shoe soles with structural properties towards reducing knee adduction moments during walking

in Biomechanics

Ziang Jiang
Paciane Bo Studer
Matthias Zäh
Christian Kryenbühl
Tingyu Wang
William R. Taylor
Qiang Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1734486

928 views

Original Research

Published on 20 Jan 2026

The development of orthodontic elastomeric ligature with sustained fluoride-releasing for the prevention of white spot lesions: an in vitro feasibility study

in Nanobiotechnology

Kativa Strickland
Peter Buschang
Ying Liu
Amal Noureldin
Reginald Taylor
Matthew Kesterke
Chi Ma
Yan Jing

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1671922

633 views

Original Research

Accepted on 19 Jan 2026

Targeted Muscle Reinnervation Attenuates Neuropathic Pain and Neuroma Development in a Rat Model of Tibial Nerve Transection

in Tissue Engineering and Regenerative Medicine

Li Li
Ainizier Yalikun
QiYue Zhang
DeBin Xiong
Tao Jiang
Fan Bu
QingTang Zhu
Aihemaitijiang Yusufu

Frontiers in Bioengineering and Biotechnology

214 views

Original Research

Accepted on 19 Jan 2026

Fabrication and characterization of small-caliber nanofibrous vascular scaffolds with sustained release of endothelial cell derivatives and heparin

in Nanobiotechnology

Ying Wang
Yawen Wang
Jiaoyan Qiu
Jing Wang
Yuanfei Wang
Manfei Fu
Tong Wu

Frontiers in Bioengineering and Biotechnology

174 views

Correction

Published on 19 Jan 2026

Correction: Electrospun bioactive polymer biomaterials enriched with collagen and platelet-rich plasma as a platform for in vitro chondrogenic differentiation of human mesenchymal stem cells

in Tissue Engineering and Regenerative Medicine

Paulina Trzaskowska
Ewa Rybak
Kamil Kopeć
Tomasz Ciach
Piotr Wieciński
Wojciech Święszkowski
Ewa Kijeńska-Gawrońska

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1770030

608 views

Original Research

Published on 19 Jan 2026

CervSpineNet: a hybrid deep learning-based approach for the segmentation of cervical spinous processes

in Biomechanics

Jay Sunil Sawant
Lama Moukheiber
Anupama Nair
Anubha Mahajan
Jaehui Byun
Ishwarya Pichaimani
Sangwook T. Yoon
Christopher T. Martin
Cassie S. Mitchell

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1733689

822 views

Original Research

Accepted on 16 Jan 2026

Design of bionic porous structure of bone scaffolds and analysis of fatigue and permeability characteristics

in Biomaterials

Chao Long
chao qun
Feng Qiu Yuan
Guo Jian Wei
zhang wei
zhang yue qin
cui jie
chen xing
zhang ming

Frontiers in Bioengineering and Biotechnology

262 views

Original Research

Published on 16 Jan 2026

Engineering human bone marrow-derived mesenchymal stromal cell aggregates for enhanced extracellular vesicle secretion in a vertical-wheel bioreactor

in Tissue Engineering and Regenerative Medicine

Danyale Berry
Breana Boirie
Mandip Singh
Li Sun
Sunghoon Jung
Yan Li
Changchun Zeng

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1664302

1,162 views

Mini Review

Published on 16 Jan 2026

Multianalyte nano-biosensor diagnostics: advances through microfluidic and AI integration

in Biosensors and Biomolecular Electronics

Shashikant Pathak
Shadi Bazazordeh
Buse Çamlıca
Ioulia Tzouvadaki

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1715719

1,450 views

Original Research

Published on 16 Jan 2026

A mobile system for whole eye perfusion supporting retinal function and surgery

in Tissue Engineering and Regenerative Medicine

Maxwell Lohss
Katelin S. Samski
Alkiviades Liasis
Hamzah Aweidah
Chiaki Komatsu
Oliver Beale
Daniel M. W. Lee
Ethan A. Rossi
Sanjeev G. Shroff
José A. Sahel

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1699876

1,316 views

Brief Research Report

Published on 16 Jan 2026

Integrated biosynthesis of the lignan (-)-pluviatolide in resting and growing E. coli cells

in Bioprocess Engineering

Ronja Knöfel
Jonas Barsig
Philipp A. Bechtold
Cigdem Günes
U. Joost Luelf
Vlada B. Urlacher

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1716646

739 views

Original Research

Published on 16 Jan 2026

Breaking through lag: enhancing intradermal electro-osmotic flow and the future of delay-free continuous glucose monitoring

in Biosensors and Biomolecular Electronics

Davide Ciarrocchi
Ruben Van den Eeckhoudt
Nurul Izni Rusli
Alessandro Zompanti
Simone Grasso
Lazzaro di Biase
Marco Santonico
Giorgio Pennazza
Irene Taurino

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1717650

971 views

Data Report

Published on 16 Jan 2026

Double defense: enhancing tobacco with cyanobacterial and thaumatin genes

in Biosafety and Biosecurity

Tetiana Kyrpa
Yelizaveta Prokhorova
Maksym Kharkhota
Mykola Kuchuk

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1667530

855 views

Original Research

Published on 16 Jan 2026

Benchmarking readability, reliability, and scientific quality of large language models in communicating organoid science

in Organoids and Organ-On-A-Chip

Man Sun
Dan Zang
Jun Chen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1750225

772 views

Original Research

Published on 16 Jan 2026

Finite element analysis of clear aligner with overhanging attachments and extended gingival coverage for interdental space closure

in Biomaterials

Guojin Zeng
Xiaoqing Ma
Dan Lin

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1636262

1,280 views

Review

Published on 15 Jan 2026

Precision measurement of stratum corneum thickness in OCT images using variational autoencoders and advanced DSP techniques

in Biosensors and Biomolecular Electronics

Haiyu Qin
Yang Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1732519

1,005 views

Original Research

Published on 15 Jan 2026

FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway

in Cell and Gene Therapy

Zhicheng Hu
Fan Li
Chunyi Hu
Qiongdan Shan
Zhouhao Tang
Meifan Jiang
Xiaojing Yi
Xixi Chen
Litai Jin
Xu Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1729166

1,834 views

Original Research

Published on 15 Jan 2026

Impaired patient-reported outcomes but preserved gait patterns 5–15 years after acetabular fracture compared with healthy controls

in Biomechanics

Selma Fensel-Merz
Elke Warmerdam
Marcel Orth
Tim Pohlemann
Emmanouil Liodakis
Bergita Ganse

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1727785

751 views

Original Research

Published on 15 Jan 2026

Automated three-dimensional left atrial analysis on computed tomography angiography: reproducibility and workflow efficiency of eight clinically relevant metrics using a deep learning pipeline

in Biomechanics

Youqi Fan
Jian Ye
Xiaoya Wang
Liuguang Song
Yaping Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1697542

537 views

11,179 articles

articles

Research advances in cryopreserved preparations of mesenchymal stem cells: technical innovations, application challenges, and quality control

A hybrid vocal fold phonatory platform for pediatric phonation modeling

Correction: GBR assisted in situ Onlay bone grafting for the posterior mandible horizontal ridge augmentation: a case report and literature review

Development of a 3D tumor model based on decellularized matrix using high-throughput approaches

Type VIII collagen: advances in matrix biology and translational promise

3D-printed shoe soles with structural properties towards reducing knee adduction moments during walking

The development of orthodontic elastomeric ligature with sustained fluoride-releasing for the prevention of white spot lesions: an in vitro feasibility study

Targeted Muscle Reinnervation Attenuates Neuropathic Pain and Neuroma Development in a Rat Model of Tibial Nerve Transection

Fabrication and characterization of small-caliber nanofibrous vascular scaffolds with sustained release of endothelial cell derivatives and heparin

Correction: Electrospun bioactive polymer biomaterials enriched with collagen and platelet-rich plasma as a platform for in vitro chondrogenic differentiation of human mesenchymal stem cells

CervSpineNet: a hybrid deep learning-based approach for the segmentation of cervical spinous processes

Design of bionic porous structure of bone scaffolds and analysis of fatigue and permeability characteristics

Engineering human bone marrow-derived mesenchymal stromal cell aggregates for enhanced extracellular vesicle secretion in a vertical-wheel bioreactor

Multianalyte nano-biosensor diagnostics: advances through microfluidic and AI integration

A mobile system for whole eye perfusion supporting retinal function and surgery

Integrated biosynthesis of the lignan (-)-pluviatolide in resting and growing E. coli cells

Breaking through lag: enhancing intradermal electro-osmotic flow and the future of delay-free continuous glucose monitoring

Double defense: enhancing tobacco with cyanobacterial and thaumatin genes

Benchmarking readability, reliability, and scientific quality of large language models in communicating organoid science

Finite element analysis of clear aligner with overhanging attachments and extended gingival coverage for interdental space closure

Precision measurement of stratum corneum thickness in OCT images using variational autoencoders and advanced DSP techniques

FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway

Impaired patient-reported outcomes but preserved gait patterns 5–15 years after acetabular fracture compared with healthy controls

Automated three-dimensional left atrial analysis on computed tomography angiography: reproducibility and workflow efficiency of eight clinically relevant metrics using a deep learning pipeline