Frontiers in Bioengineering and Biotechnology

Original Research

Accepted on 12 May 2026

Integrated Optical and Thermal Modeling for the Development of a Scalable Multi-Sample Light-Assisted Drying Platform for Biologic Stabilization

in Bioprocess Engineering

Anteneh A Tsegaye
Alexander J Suptela
Russell G Keanini
Susan R Trammell

Frontiers in Bioengineering and Biotechnology

Original Research

Published on 08 May 2026

Interaction between microorganisms and flavour products during cigar fermentation promoted by citrus Reticulata-“Chenpi” derived Enterobacter G5Z-2: based on multi-omics studies and microbial profiles

in Bioprocess Engineering

Jian Zhang
Chong Chen
Yang Hu
Shiru Jia
Bo Li
Wanrong Hu
Yun Jia
Dongliang Li
Yuanfa Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1785975

452 views

Original Research

Published on 07 May 2026

Physiological and metabolic responses of Anabaena variabilis and Chlorella pyrenoidosa under lead stress: implications for microalgal bioremediation

in Bioprocess Engineering

Kholoud K. Alzahrani

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1842216

439 views

Original Research

Published on 04 May 2026

Quantitative determination of trace principal components with high specific activity in menotropins

in Bioprocess Engineering

Yue Sun
Heyang Li
Xinyue Hu
Shuqing Luo
Xiaoming Zhang
Lyuyin Wang
Yi Li
Ping Lyu
Jing Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1783311

509 views

Original Research

Accepted on 28 Apr 2026

Microbial Induced Calcium Carbonate Precipitation Under Extreme Environmental process and Mechanical Performance of Biomineralization Conditions: Impacts on Concrete

in Bioprocess Engineering

Mai M. Abdelwahed
Amany M. Reyad
Ahmed. Abd-Alazim
Gehad Mokhtar

Frontiers in Bioengineering and Biotechnology

238 views

Original Research

Accepted on 27 Apr 2026

Valorization of Acid-Hydrolyzed Tea Stem Waste for Sustainable Biodiesel Production using Chlorella vulgaris: A Biorefinery Approach

in Bioprocess Engineering

Charith Akalanka Dodangodage
Nisansala H. Rathnapriya
Geethaka Nethsara Gamage
Jagath C. Kasturiarachchi
Thilini A. Perera
Sanjitha Dilan Rajapakshe
Sayuri S Niyangoda
Rangika Umesh Halwatura

Frontiers in Bioengineering and Biotechnology

236 views

Original Research

Published on 15 Apr 2026

Serum-free production of anti-huCD20(hγ1)-IL2no-alpha immunocytokine: a promising therapeutic for B-NHL

in Bioprocess Engineering

Debbie Laura Bergantiños Albernas
Ernesto Azahares Valdivia
Carlos Lázaro Pérez Rosales
Ana Laura Hurtado de Mendoza Arrieta
Claudia de las Mercedes Castellanos Díaz
Miguel Ángel González
Katya Sosa Aguiar
Tania Gómez Peña
Julio Felipe Santo Tomás Pompa
Julio Palacios-Oliva

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1773646

477 views

Original Research

Published on 14 Apr 2026

Unique DNA impacts on transient Expi293TMPRO expression for enhancing biotherapeutic protein production

in Bioprocess Engineering

Bo Hee Shin
Jing Zhou
Audrey M. Vogt
Lauren Gebhardt
Molica Abel
Hamza Sahil
Fabrice Lamour
Anna Kimeu
Ian R. Wallace-Moyer
Sean Lim

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1786185

706 views

Review

Accepted on 07 Apr 2026

The Landscape of Antibody Production Systems: Recombinant Expression for Research, Diagnostics and Therapy

in Bioprocess Engineering

Esther Veronika Wenzel
Laila Al-Halabi-Frenzel
Seyhan Demiral
André Frenzel
Dianne Celine Gnann
Martha Charlotte-Elisabeth Keitel
Nina Lehmler
Tarushyam Mukherjee
Justus Rauls
Thomas Schirrmann

Frontiers in Bioengineering and Biotechnology

446 views

Review

Published on 01 Apr 2026

Microbial community assembly in the fermentation of cigar tobacco leaves

in Bioprocess Engineering

Tianfei Zheng
Dongfeng Guo
Yaqi Shi
Jinlong Zhou
Kun Zong
Naihong Ding
Xingjiang Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1779182

537 views

Editorial

Published on 16 Mar 2026

Editorial: Advanced bioprocessing strategies for tissue engineering and biomimetic modelling applications

in Bioprocess Engineering

João C. Silva
Carlos A. V. Rodrigues
Eirini Velliou
Diana Massai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1826813

436 views

Original Research

Published on 13 Mar 2026

A novel PolyAr87-based cell transfection protocol for nanobody expression optimized via a targeted design of transfection approach

in Bioprocess Engineering

Lautaro Fidel Bracco
Giovanna Lucia Liguori
Antonella Lanati
Juan Manuel Lázaro-Martínez
Mariela Bollini
Leonardo Poggio
Marina Bok
Lorena Itatí Ibañez
Viviana Parreño

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1720185

1,045 views

Review

Published on 27 Feb 2026

Structural improvement towards the efficiency of biodigesters in the 21st century: a review of the different designs

in Bioprocess Engineering

Takalani Nethavhanani
Vhutshilo Nekhubvi
Lutendo Mathomu
Nnditshedzeni Eric Maluta

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1721607

920 views

Original Research

Published on 17 Feb 2026

Impact of keto leucine and isoleucine on CHO cell central carbon metabolism and performance in fed-batch and steady-state perfusion

in Bioprocess Engineering

Philipp Reifenberg
Daniel Benjamin
Maxime Le Mignon
Aline Zimmer

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1708088

998 views

Original Research

Published on 30 Jan 2026

Towards a cleaner CHO chassis: systematic knockout of host cell proteins for efficient biopharmaceutical manufacturing

in Bioprocess Engineering

Jannis Peter Marzluf
Jennifer Klein
Daniela Kirchmeier
Alexander Stärk
Daniel Ziegner
Markus Gehrung
Franziska Rauh
Merle Rattay
Christoph Zehe
Ann-Cathrin Leroux

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1750646

2,990 views

Original Research

Published on 21 Jan 2026

Whole-genome DNA methylation analysis of Chinese hamster ovary cells undergoing media adaptation

in Bioprocess Engineering

Suki Roy
Jasrene Kaur Sandhu
Lingzhi Huang
Abraham Wong
Guo Xuan Wan
Frank Lyko
Emeka Ignatius Igwe
Florian Böhl

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1716758

1,610 views

Original Research

Published on 21 Jan 2026

Modeling and validating of oxygen transport in wave bioreactors: optimized experimental mass transfer method and novel Lattice-Boltzmann CFD approach

in Bioprocess Engineering

S. Piontek
J. Fitschen
C. Weiland
T. Habicher
M. Schlüter
T. Wucherpfennig

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1688774

1,624 views

Brief Research Report

Published on 16 Jan 2026

Integrated biosynthesis of the lignan (-)-pluviatolide in resting and growing E. coli cells

in Bioprocess Engineering

Ronja Knöfel
Jonas Barsig
Philipp A. Bechtold
Cigdem Günes
U. Joost Luelf
Vlada B. Urlacher

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1716646

1,095 views

Original Research

Published on 15 Jan 2026

Effects of low-serum adaptation on growth and protein expression in stably lactoferrin-overexpressing mammary alveolar cells

in Bioprocess Engineering

Zhenxing Qiang
Xiaoqian Cai
Zhenzhen Zhang
Hui Wang
Qiuying Wang
Yajing Ji
Guangpeng Li
Guanghua Su
Lei Yang
Weicang Qiao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1731548

939 views

Review

Published on 15 Jan 2026

Bioleaching as a biotechnological tool for metal recovery: from sewage to space mining

in Bioprocess Engineering

Archana Paimpillil Abraham
Simone Schopf

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1712157

4,061 views
1 citation

Original Research

Published on 12 Jan 2026

Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation

in Bioprocess Engineering

Pierre Springuel
Pedro Silva Couto
Dale J. Stibbs
Michal Szelwicki
Amanda Frangleton
Timo Schmidberger
Ajith George
Fern Slingsby
Nicola Bevan
Asma Ahmad

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1694134

4,267 views

Original Research

Published on 12 Jan 2026

Life on the rocks: unexpected enzyme activity of the extremophilic black fungus Knufia chersonesos

in Bioprocess Engineering

Sophia Mihalyi
Christian Zimmermann
Felice Quartinello
Donatella Tesei
Astrid R. Mach-Aigner
Georg Guebitz
Doris Ribitsch

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1720118

1,030 views

Review

Published on 09 Jan 2026

Cis-abienol from tobacco trichomes to ambergris-like compounds: advances in biosynthesis, fermentation, and industrial applications

in Bioprocess Engineering

Wenting Wang
Xinlong Zhang
Wei Hu
Shen Huang
Robina Manzoor
Aamir Rasool

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1713206

1,317 views

Review

Published on 08 Jan 2026

Prospects and challenges regarding biosurfactants in advancing the petroleum industry

in Bioprocess Engineering

Ojasvini Ahluwalia
Niketan Patel
Nikhil Narmeta
Sandra Guzman Sanchez
Alexandre Soares Rosado

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1697361

2,696 views

1,022 articles

articles

Integrated Optical and Thermal Modeling for the Development of a Scalable Multi-Sample Light-Assisted Drying Platform for Biologic Stabilization

Interaction between microorganisms and flavour products during cigar fermentation promoted by citrus Reticulata-“Chenpi” derived Enterobacter G5Z-2: based on multi-omics studies and microbial profiles

Physiological and metabolic responses of Anabaena variabilis and Chlorella pyrenoidosa under lead stress: implications for microalgal bioremediation

Quantitative determination of trace principal components with high specific activity in menotropins

Microbial Induced Calcium Carbonate Precipitation Under Extreme Environmental process and Mechanical Performance of Biomineralization Conditions: Impacts on Concrete

Valorization of Acid-Hydrolyzed Tea Stem Waste for Sustainable Biodiesel Production using Chlorella vulgaris: A Biorefinery Approach

Serum-free production of anti-huCD20(hγ1)-IL2no-alpha immunocytokine: a promising therapeutic for B-NHL

Unique DNA impacts on transient Expi293TMPRO expression for enhancing biotherapeutic protein production

The Landscape of Antibody Production Systems: Recombinant Expression for Research, Diagnostics and Therapy

Microbial community assembly in the fermentation of cigar tobacco leaves

Editorial: Advanced bioprocessing strategies for tissue engineering and biomimetic modelling applications

A novel PolyAr87-based cell transfection protocol for nanobody expression optimized via a targeted design of transfection approach

Structural improvement towards the efficiency of biodigesters in the 21st century: a review of the different designs

Impact of keto leucine and isoleucine on CHO cell central carbon metabolism and performance in fed-batch and steady-state perfusion

Towards a cleaner CHO chassis: systematic knockout of host cell proteins for efficient biopharmaceutical manufacturing

Whole-genome DNA methylation analysis of Chinese hamster ovary cells undergoing media adaptation

Modeling and validating of oxygen transport in wave bioreactors: optimized experimental mass transfer method and novel Lattice-Boltzmann CFD approach

Integrated biosynthesis of the lignan (-)-pluviatolide in resting and growing E. coli cells

Effects of low-serum adaptation on growth and protein expression in stably lactoferrin-overexpressing mammary alveolar cells

Bioleaching as a biotechnological tool for metal recovery: from sewage to space mining

Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation

Life on the rocks: unexpected enzyme activity of the extremophilic black fungus Knufia chersonesos

Cis-abienol from tobacco trichomes to ambergris-like compounds: advances in biosynthesis, fermentation, and industrial applications

Prospects and challenges regarding biosurfactants in advancing the petroleum industry