Frontiers in Bioengineering and Biotechnology

Original Research

Accepted on 10 Jul 2025

Bayesian experimental design for optimizing medium composition and biomass formation of tobacco BY-2 cell suspension cultures in stirred-tank bioreactors

in Bioprocess Engineering

Lars Leyendecker
Henrik Nausch
Christian Wergers
Dirk Scheffler
Robert Schmitt

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1617319

134 views

Review

Published on 10 Jul 2025

Insights into bone and cartilage responses to pulsed electromagnetic field stimulation: a review with quantitative comparisons

in Bioprocess Engineering

Beatrice Masante
Stefano Gabetti
Joao C. Silva
Giovanni Putame
Simone Israel
Cristina Bignardi
Diana Massai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1557572

413 views

Original Research

Accepted on 09 Jul 2025

Enhanced Cancer Cell Sorting Using Lab-on-a-Disc Pattern Design with Magnetic and Centrifugal Forces

in Bioprocess Engineering

Bill Cheng
Wei-Cheng Chao
Yi-Han Chen
Yao-Tsung Lin

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611313

170 views

Review

Published on 09 Jul 2025

Recent advances and future directions on GLA-producing organisms

in Bioprocess Engineering

Mojgan Latifi
Foroozan Jalali Bidgoli
Helia Hajihassani
Danial Hassani
Pär K. Ingvarsson
Naser Farrokhi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1567840

539 views

Original Research

Published on 07 Jul 2025

Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium

in Bioprocess Engineering

Ruoxuan Wu
Tianji Zhang
Siran Zhao
Marco Maccarana
Jin-Ping Li
Chao Li
Hui Cao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1597344

804 views

Original Research

Accepted on 04 Jul 2025

Adaptive Responses of Gordonia alkanivorans IEGM 1277 to the Action of Meloxicam and its Efficient Biodegradation

in Bioprocess Engineering

Semyon Tyan
Nadezhda Kostrikina
Vladimir Sorokin
Andrey Mulyukin
Irina Ivshina

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1603975

227 views

Methods

Published on 27 Jun 2025

Optimizing protein yield from growing deer antlers

in Bioprocess Engineering

Nicolás Alegría-Aravena
María-Pilar López-Garrido
Josefa Quiroz-Troncoso
Raquel González-Martos
Marta Sánchez-Díez
Clara Gavira-O’Neill
Andrés J. García-Díaz
Tomás Landete-Castillejos
Carmen Ramírez-Castillejo
Louis Chonco

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1612239

903 views

Original Research

Accepted on 23 Jun 2025

Hyaluronidases improve the hyaluronic acid yield during the fermentation of Streptococcus zooepidemicus

in Bioprocess Engineering

Chuan-Li Kang
De-Qiang Zheng
Zhi-Yuan Yao
Kang Yang
Yuxue Zhao
Zihan Mao
Yang Liu
Haijun Li
Jin-Song Gong
Lei Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1625009

250 views

Original Research

Accepted on 16 Jun 2025

Cell Specific Perfusion Rates Drive Growth Dynamics and Metabolism in CHO N-1 Perfusion Processes Independent of Perfusion Rate Control Method

in Bioprocess Engineering

Julia Walther
Tiago Ribeiro Da Costa
Lydia Winkler
Jochen Schaub
Tobias Habicher

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1608889

492 views

Original Research

Accepted on 06 Jun 2025

Automated, aseptic sampling with small-volume capacity from microbioreactors for cell therapy process analysis

in Bioprocess Engineering

Zhi Xian Chan
Shruthi Pandi Chelvam
Wei-Xiang Sin
Denise Bei Lin Teo
Ahmad Amirul Abdul Rahim
Ying Ying Wu
Dan Liu
Michael Birnbaum
Derrick Yong
Rajeev Ram

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1612648

532 views

Brief Research Report

Published on 05 Jun 2025

Unlocking efficiency in column chromatography with packed bed supporting inserts

in Bioprocess Engineering

Romone M. Fancy
David H. Abraham
Matthew R. Taylor
Cole McMullin
Nicholas S. Brann
Daniel M. Bailey
David I. Brown
Heather Bethea Horne
Leslie S. Wolfe

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1613174

1,735 views

Review

Published on 04 Jun 2025

Enzymatic approaches to nicotinic acid synthesis: recent advances and future prospects

in Bioprocess Engineering

Rahul Vikram Singh
Vipin Chandra Kalia
Krishika Sambyal
Bakul Singh
Anurag Kumar
Jung-Kul Lee

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1585736

3,469 views

Original Research

Published on 02 Jun 2025

Optimising and adapting perfusion feeds in serum-free medium to intensify CAR-T cell expansion in stirred-tank bioreactors

in Bioprocess Engineering

Pierre Springuel
Tiffany Hood
Fern Slingsby
Timo Schmidberger
Nicola Bevan
Noushin Dianat
Julia Hengst
Qasim A. Rafiq

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1593895

2,370 views

Original Research

Published on 30 May 2025

Accuracy and cost comparison of 3D-printed guides in complex spinal deformity correction: direct vs indirect design

in Bioprocess Engineering

Wei Yang
Wei Guo
Wen-Jun Wu
Rong Ma
Zemin Wang
Honglai Zhang
Wanzhong Yang
Zhaohui Ge

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611998

995 views

Original Research

Published on 30 May 2025

Perfusion process with tangential flow filtration for oncolytic VSV-GP production

in Bioprocess Engineering

Orsolya Hamusics
Anja Wittmann
Katrin Hasler
Sabrina Müller
Daniel Birk
Ingo H. Gorr
Alexander Brix
Jorge Soza-Ried

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1588293

1,307 views

Original Research

Published on 21 May 2025

mAb production kinetics in CHO batch culture: exploring extracellular and intracellular dynamics

in Bioprocess Engineering

Alejandro Avilan Garzon
Bruno Ebel
Cédric Paris
Samuel Schneider
David Pfister
Eric Olmos

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1546105

1,897 views