Frontiers in Bioengineering and Biotechnology

Review

Published on 20 Jul 2021

An Overview of Methods and Tools for Transfection of Eukaryotic Cells in vitro

in Cell and Gene Therapy

Agnieszka Fus-Kujawa
Pawel Prus
Karolina Bajdak-Rusinek
Paulina Teper
Katarzyna Gawron
Agnieszka Kowalczuk
Aleksander L. Sieron

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.701031

112,828 views
117 citations

Editorial

Published on 19 Jul 2021

Editorial: Advanced Cell Culture Technologies to Boost Cell-Based Therapies

in Cell and Gene Therapy

Dominik Egger
Aldo R. Boccaccini
Diego Correa
Cornelia Kasper
Fergal J. O’Brien

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.727298

2,821 views

Original Research

Published on 15 Jul 2021

One-Time Optimization of Advanced T Cell Culture Media Using a Machine Learning Pipeline

in Cell and Gene Therapy

Paul Grzesik
Sebastian C. Warth

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.614324

9,337 views
21 citations

Original Research

Published on 09 Jul 2021

Clinical and Molecular Correlates of NLRC5 Expression in Patients With Melanoma

in Cell and Gene Therapy

Lei Lv
Qinqin Wei
Zhiwen Wang
Yujia Zhao
Ni Chen
Qiyi Yi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.690186

4,656 views
6 citations

Editorial

Published on 02 Jul 2021

Editorial: Cell-Based Approaches for Modulating Cartilage and Bone Phenotype

in Cell and Gene Therapy

Roberto Narcisi
Elena Jones

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.716323

1,574 views
1 citation

Original Research

Published on 01 Jul 2021

Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels

in Cell and Gene Therapy

Alessandro Certelli
Paolo Valente
Andrea Uccelli
Andrea Grosso
Nunzia Di Maggio
Rosalinda D’Amico
Priscilla S. Briquez
Jeffrey A. Hubbell
Thomas Wolff
Lorenz Gürke

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.688467

5,188 views
26 citations

Original Research

Published on 21 Jun 2021

Transplantation of Human Gingiva-Derived Mesenchymal Stem Cells Ameliorates Neurotic Erectile Dysfunction in a Rat Model

in Cell and Gene Therapy

Juekun Wu
Zehong Chen
Fuyan Zhong
Wende Yang
Xi Ouyang
Xiaolei Ma
Songguo Zheng
Hongbo Wei

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.630076

4,239 views
13 citations

Systematic Review

Published on 18 Jun 2021

Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives

in Cell and Gene Therapy

Isabel C. Hostettler
Narayan Jayashankar
Christos Bikis
Stefan Wanderer
Edin Nevzati
Ravindran Karuppiah
Vicknes Waran
Daniel Kalbermatten
Luigi Mariani
Serge Marbacher

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.659413

6,674 views
9 citations

Original Research

Published on 09 Jun 2021

Fabrication and Characterization of a Biomaterial Based on Extracellular-Vesicle Functionalized Graphene Oxide

in Cell and Gene Therapy

Julia Driscoll
Anuradha Moirangthem
Irene K. Yan
Tushar Patel

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.686510

4,363 views
10 citations

Original Research

Published on 07 Jun 2021

New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles

in Cell and Gene Therapy

Thanh Huyen Phan
Shiva Kamini Divakarla
Jia Hao Yeo
Qingyu Lei
Priyanka Tharkar
Taisa Nogueira Pansani
Kathryn G. Leslie
Maggie Tong
Victoria A. Coleman
Åsa Jämting

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.669537

11,990 views
10 citations

Original Research

Published on 28 May 2021

Protein Arginine Methyltransferase 5 Promotes Esophageal Squamous Cell Carcinoma Proliferation and Metastasis via LKB1/AMPK/mTOR Signaling Pathway

in Cell and Gene Therapy

Yu-ru Chen
Hua-ni Li
Lian-jun Zhang
Chong Zhang
Jin-guang He

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.645375

4,008 views
12 citations

Original Research

Published on 26 May 2021

A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells

in Cell and Gene Therapy

Aliosha I. Figueroa-Valdés
Catalina de la Fuente
Yessia Hidalgo
Ana María Vega-Letter
Rafael Tapia-Limonchi
Maroun Khoury
Francisca Alcayaga-Miranda

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.619930

10,700 views
10 citations

Original Research

Published on 25 May 2021

Measuring and Modeling Oxygen Transport and Consumption in 3D Hydrogels Containing Chondrocytes and Stem Cells of Different Tissue Origins

in Cell and Gene Therapy

Simon F. Carroll
Conor T. Buckley
Daniel J. Kelly

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.591126

4,767 views
6 citations

Editorial

Published on 24 May 2021

Editorial: Bone and Cartilage Regeneration With Extracellular Vesicles

in Cell and Gene Therapy

Roberta Tasso
Susanne Grässel
Frank Zaucke

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.692836

3,052 views

Review

Published on 13 May 2021

Mesenchymal Stromal Cells and Their Secretome: New Therapeutic Perspectives for Skeletal Muscle Regeneration

in Cell and Gene Therapy

Martina Sandonà
Lorena Di Pietro
Federica Esposito
Alessia Ventura
Antonietta Rosa Silini
Ornella Parolini
Valentina Saccone

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.652970

16,818 views
71 citations

Mini Review

Published on 23 Apr 2021

Is Extracellular Vesicle-Based Therapy the Next Answer for Cartilage Regeneration?

in Cell and Gene Therapy

Émilie Velot
Henning Madry
Jagadeesh K. Venkatesan
Arnaud Bianchi
Magali Cucchiarini

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.645039

8,559 views
20 citations

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Articles

An Overview of Methods and Tools for Transfection of Eukaryotic Cells in vitro

Editorial: Advanced Cell Culture Technologies to Boost Cell-Based Therapies

One-Time Optimization of Advanced T Cell Culture Media Using a Machine Learning Pipeline

Clinical and Molecular Correlates of NLRC5 Expression in Patients With Melanoma

Editorial: Cell-Based Approaches for Modulating Cartilage and Bone Phenotype

Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels

Transplantation of Human Gingiva-Derived Mesenchymal Stem Cells Ameliorates Neurotic Erectile Dysfunction in a Rat Model

Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives

Fabrication and Characterization of a Biomaterial Based on Extracellular-Vesicle Functionalized Graphene Oxide

New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles

Protein Arginine Methyltransferase 5 Promotes Esophageal Squamous Cell Carcinoma Proliferation and Metastasis via LKB1/AMPK/mTOR Signaling Pathway

A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells

Measuring and Modeling Oxygen Transport and Consumption in 3D Hydrogels Containing Chondrocytes and Stem Cells of Different Tissue Origins

Editorial: Bone and Cartilage Regeneration With Extracellular Vesicles

Mesenchymal Stromal Cells and Their Secretome: New Therapeutic Perspectives for Skeletal Muscle Regeneration

Is Extracellular Vesicle-Based Therapy the Next Answer for Cartilage Regeneration?