Frontiers in Bioengineering and Biotechnology

Original Research

Published on 08 Oct 2021

Prioritization of Diagnostic and Prognostic Biomarkers for Lupus Nephritis Based on Integrated Bioinformatics Analyses

in Cell and Gene Therapy

Zhimin Chen
Ruilong Lan
Keng Ye
Hong Chen
Caiming Chen
Yanfang Xu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.717234

7,288 views
19 citations

Original Research

Published on 06 Oct 2021

Application of Bioinformatics Analysis to Identify Important Pathways and Hub Genes in Ovarian Cancer Affected by WT1

in Cell and Gene Therapy

Kai Meng
Jinghe Cao
Yehao Dong
Mengchen Zhang
Chunfeng Ji
Xiaomei Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.741051

6,775 views
6 citations

Original Research

Published on 05 Oct 2021

Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells

in Cell and Gene Therapy

Mustafa Burak Acar
Şerife Ayaz-Güner
Zeynep Gunaydin
Musa Karakukcu
Gianfranco Peluso
Giovanni Di Bernardo
Servet Özcan
Umberto Galderisi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.730813

7,645 views
26 citations

Original Research

Published on 17 Sep 2021

The Therapeutic Efficacy of Adipose Tissue-Derived Mesenchymal Stem Cell Conditioned Medium on Experimental Colitis Was Improved by the Serum From Colitis Rats

in Cell and Gene Therapy

Li-li Qi
Zhe-yu Fan
Hai-guang Mao
Jin-bo Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.694908

4,455 views
11 citations

Original Research

Published on 25 Aug 2021

Extracellular Vesicles Derived From Human Umbilical Cord Mesenchymal Stem Cells Protect Against DOX-Induced Heart Failure Through the miR-100-5p/NOX4 Pathway

in Cell and Gene Therapy

Zhenglong Zhong
Yuqing Tian
Xiaoming Luo
Jianjie Zou
Lin Wu
Julong Tian

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.703241

5,027 views
27 citations

Original Research

Published on 03 Aug 2021

PhP.B Enhanced Adeno-Associated Virus Mediated-Expression Following Systemic Delivery or Direct Brain Administration

in Cell and Gene Therapy

Kimberly L. Pietersz
Francois Du Plessis
Stephan M. Pouw
Jolanda M. Liefhebber
Sander J. van Deventer
Gerard J. M. Martens
Pavlina S. Konstantinova
Bas Blits

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.679483

17,284 views
10 citations

Original Research

Published on 28 Jul 2021

Hypomethylation of Rnase6 Promoter Enhances Proliferation and Migration of Murine Aortic Vascular Smooth Muscle Cells and Aggravates Atherosclerosis in Mice

in Cell and Gene Therapy

YongPeng Fang
JinShuang Li
XuDong Niu
NingShun Ma
Jia Zhao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.695461

3,910 views
8 citations

Review

Published on 20 Jul 2021

An Overview of Methods and Tools for Transfection of Eukaryotic Cells in vitro

in Cell and Gene Therapy

Agnieszka Fus-Kujawa
Pawel Prus
Karolina Bajdak-Rusinek
Paulina Teper
Katarzyna Gawron
Agnieszka Kowalczuk
Aleksander L. Sieron

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.701031

120,110 views
134 citations

Editorial

Published on 19 Jul 2021

Editorial: Advanced Cell Culture Technologies to Boost Cell-Based Therapies

in Cell and Gene Therapy

Dominik Egger
Aldo R. Boccaccini
Diego Correa
Cornelia Kasper
Fergal J. O’Brien

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.727298

3,118 views

Original Research

Published on 15 Jul 2021

One-Time Optimization of Advanced T Cell Culture Media Using a Machine Learning Pipeline

in Cell and Gene Therapy

Paul Grzesik
Sebastian C. Warth

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.614324

10,290 views
22 citations

Original Research

Published on 09 Jul 2021

Clinical and Molecular Correlates of NLRC5 Expression in Patients With Melanoma

in Cell and Gene Therapy

Lei Lv
Qinqin Wei
Zhiwen Wang
Yujia Zhao
Ni Chen
Qiyi Yi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.690186

5,112 views
6 citations

Editorial

Published on 02 Jul 2021

Editorial: Cell-Based Approaches for Modulating Cartilage and Bone Phenotype

in Cell and Gene Therapy

Roberto Narcisi
Elena Jones

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.716323

1,736 views
1 citation

Original Research

Published on 01 Jul 2021

Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels

in Cell and Gene Therapy

Alessandro Certelli
Paolo Valente
Andrea Uccelli
Andrea Grosso
Nunzia Di Maggio
Rosalinda D’Amico
Priscilla S. Briquez
Jeffrey A. Hubbell
Thomas Wolff
Lorenz Gürke

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.688467

5,749 views
31 citations

Original Research

Published on 21 Jun 2021

Transplantation of Human Gingiva-Derived Mesenchymal Stem Cells Ameliorates Neurotic Erectile Dysfunction in a Rat Model

in Cell and Gene Therapy

Juekun Wu
Zehong Chen
Fuyan Zhong
Wende Yang
Xi Ouyang
Xiaolei Ma
Songguo Zheng
Hongbo Wei

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.630076

4,690 views
14 citations

Systematic Review

Published on 18 Jun 2021

Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives

in Cell and Gene Therapy

Isabel C. Hostettler
Narayan Jayashankar
Christos Bikis
Stefan Wanderer
Edin Nevzati
Ravindran Karuppiah
Vicknes Waran
Daniel Kalbermatten
Luigi Mariani
Serge Marbacher

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.659413

8,022 views
9 citations

Original Research

Published on 09 Jun 2021

Fabrication and Characterization of a Biomaterial Based on Extracellular-Vesicle Functionalized Graphene Oxide

in Cell and Gene Therapy

Julia Driscoll
Anuradha Moirangthem
Irene K. Yan
Tushar Patel

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.686510

4,782 views
10 citations