Frontiers in Bioengineering and Biotechnology

Review

Published on 28 Jun 2022

Gene Therapy in Orthopaedics: Progress and Challenges in Pre-Clinical Development and Translation

in Cell and Gene Therapy

Rachael S. Watson-Levings
Glyn D. Palmer
Padraic P. Levings
E. Anthony Dacanay
Christopher H. Evans
Steven C. Ghivizzani

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.901317

8,346 views
15 citations

Original Research

Published on 24 Jun 2022

An Overview of Current Research on Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Bibliometric Analysis From 2009 to 2021

in Cell and Gene Therapy

Xudong Zhang
Yimeng Lu
Shanshan Wu
Siwen Zhang
Shuyu Li
Jichun Tan

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.910812

8,886 views
23 citations

Review

Published on 22 Jun 2022

Chimeric Antigen Receptor T-Cells: An Overview of Concepts, Applications, Limitations, and Proposed Solutions

in Cell and Gene Therapy

Alaa Alnefaie
Sarah Albogami
Yousif Asiri
Tanveer Ahmad
Saqer S. Alotaibi
Mohammad M. Al-Sanea
Hisham Althobaiti

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.797440

33,309 views
62 citations

Original Research

Published on 22 Jun 2022

In vitro Exposure to Inflammatory Mediators Affects the Differentiation of Mesenchymal Progenitors

in Cell and Gene Therapy

S. Marsh
T. Constantin-Teodosiu
V. Chapman
V. Sottile

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.908507

2,615 views
5 citations

Review

Published on 15 Jun 2022

A Progress Report and Roadmap for Microphysiological Systems and Organ-On-A-Chip Technologies to Be More Predictive Models in Human (Knee) Osteoarthritis

in Cell and Gene Therapy

Mario Rothbauer
Eva I. Reihs
Anita Fischer
Reinhard Windhager
Florien Jenner
Stefan Toegel

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.886360

7,509 views
6 citations

Original Research

Published on 14 Jun 2022

The Role of Hypoxia in Improving the Therapeutic Potential of Mesenchymal Stromal Cells. A Comparative Study From Healthy Lung and Congenital Pulmonary Airway Malformations in Infants

in Cell and Gene Therapy

Serena Silvestro
Francesca Diomede
Luigi Chiricosta
Valeria Domenica Zingale
Guya Diletta Marconi
Jacopo Pizzicannella
Andrea Valeri
Maria Antonietta Avanzini
Valeria Calcaterra
Gloria Pelizzo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.868486

2,453 views
4 citations

Original Research

Published on 03 Jun 2022

Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications

in Cell and Gene Therapy

Madeleine St. Peter
Douglas E. Brough
Anna Lawrence
Jennifer Nelson-Brantley
Peixin Huang
Jennifer Harre
Athanasia Warnecke
Hinrich Staecker

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.892969

3,064 views
5 citations

Original Research

Published on 02 Jun 2022

Identification of Type 2 Diabetes Biomarkers From Mixed Single-Cell Sequencing Data With Feature Selection Methods

in Cell and Gene Therapy

Zhandong Li
Xiaoyong Pan
Yu-Dong Cai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.890901

3,725 views
8 citations

Original Research

Published on 01 Jun 2022

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modulate Hematopoietic Stem and Progenitor Cell Viability and the Expression of Cell Cycle Regulators in an Age-dependent Manner

in Cell and Gene Therapy

Pascal Fichtel
Malte von Bonin
Robert Kuhnert
Kristin Möbus
Martin Bornhäuser
Manja Wobus

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.892661

4,057 views
15 citations

Original Research

Published on 30 May 2022

Identifying In Vitro Cultured Human Hepatocytes Markers with Machine Learning Methods Based on Single-Cell RNA-Seq Data

in Cell and Gene Therapy

ZhanDong Li
FeiMing Huang
Lei Chen
Tao Huang
Yu-Dong Cai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.916309

4,165 views
3 citations

Review

Published on 27 May 2022

The Hunt Is On! In Pursuit of the Ideal Stem Cell Population for Cartilage Regeneration

in Cell and Gene Therapy

T. Mark Campbell
F. Jeffrey Dilworth
David S. Allan
Guy Trudel

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.866148

5,403 views
7 citations

Systematic Review

Published on 26 May 2022

Pre-Eclampsia Biomarkers for Women With Type 1 Diabetes Mellitus: A Comprehensive Review of Recent Literature

in Cell and Gene Therapy

Katrina Z. Freimane
Lauren Kerrigan
Kelly-Ann Eastwood
Chris J. Watson

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.809528

3,709 views
2 citations

Original Research

Published on 26 May 2022

Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells

in Cell and Gene Therapy

Qin Li
Rui-Fang Yan
Yong-Xiao Yang
Chun-liu Mi
Yan-long Jia
Tian-Yun Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.840600

3,267 views
5 citations

Review

Published on 25 May 2022

Advances in Stem Cell Therapies for Rotator Cuff Injuries

in Cell and Gene Therapy

Hao-Nan Wang
Xiao Rong
Lu-Ming Yang
Wei-Zhong Hua
Guo-Xin Ni

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.866195

27,172 views
14 citations

Original Research

Published on 20 May 2022

Changes in Elastic Moduli of Fibrin Hydrogels Within the Myogenic Range Alter Behavior of Murine C2C12 and Human C25 Myoblasts Differently

in Cell and Gene Therapy

Janine Tomasch
Babette Maleiner
Philipp Heher
Manuel Rufin
Orestis G. Andriotis
Philipp J. Thurner
Heinz Redl
Christiane Fuchs
Andreas H. Teuschl-Woller

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.836520

4,324 views
7 citations

Review

Published on 19 May 2022

Non-Coding RNAs Delivery by Small Extracellular Vesicles and Their Applications in Ovarian Cancer

in Cell and Gene Therapy

Mu Liu
Xiaofang Zhou
Jie Tang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.876151

2,889 views
2 citations

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Articles

Gene Therapy in Orthopaedics: Progress and Challenges in Pre-Clinical Development and Translation

An Overview of Current Research on Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Bibliometric Analysis From 2009 to 2021

Chimeric Antigen Receptor T-Cells: An Overview of Concepts, Applications, Limitations, and Proposed Solutions

In vitro Exposure to Inflammatory Mediators Affects the Differentiation of Mesenchymal Progenitors

A Progress Report and Roadmap for Microphysiological Systems and Organ-On-A-Chip Technologies to Be More Predictive Models in Human (Knee) Osteoarthritis

The Role of Hypoxia in Improving the Therapeutic Potential of Mesenchymal Stromal Cells. A Comparative Study From Healthy Lung and Congenital Pulmonary Airway Malformations in Infants

Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications

Identification of Type 2 Diabetes Biomarkers From Mixed Single-Cell Sequencing Data With Feature Selection Methods

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modulate Hematopoietic Stem and Progenitor Cell Viability and the Expression of Cell Cycle Regulators in an Age-dependent Manner

Identifying In Vitro Cultured Human Hepatocytes Markers with Machine Learning Methods Based on Single-Cell RNA-Seq Data

The Hunt Is On! In Pursuit of the Ideal Stem Cell Population for Cartilage Regeneration

Pre-Eclampsia Biomarkers for Women With Type 1 Diabetes Mellitus: A Comprehensive Review of Recent Literature

Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells

Advances in Stem Cell Therapies for Rotator Cuff Injuries

Changes in Elastic Moduli of Fibrin Hydrogels Within the Myogenic Range Alter Behavior of Murine C2C12 and Human C25 Myoblasts Differently

Non-Coding RNAs Delivery by Small Extracellular Vesicles and Their Applications in Ovarian Cancer