Frontiers in Bioengineering and Biotechnology

Original Research

Published on 14 Nov 2025

Efficient production of functional cholera toxin B subunit using geminiviral replicons in Nicotiana benthamiana

in Synthetic Biology

Nan-Sun Kim
Jihyea Lee
Juho Lee
Seon-Kyeong Lee
Kyeong-Ryeol Lee

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1693569

369 views

Original Research

Published on 12 Nov 2025

Discovery and optimization of a synthetic small protein domain targeting antibodies

in Synthetic Biology

Ana Margarida Gonçalves Carvalho Dias
Manuel João Brandão Matos
Cátia Soares
Carolina Natal
Ana Sofia Pina
Ana Cecília Afonso Roque

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1678111

678 views

Opinion

Accepted on 10 Nov 2025

Advancing cadmium bioremediation: future directions for CadR display strategies

in Synthetic Biology

Chang-ye Hui

Frontiers in Bioengineering and Biotechnology

105 views

Review

Published on 10 Nov 2025

Biorecycling of polyethylene (PE): an integrated effort in pretreatment, degradation, and upcycling

in Synthetic Biology

Umer Abid
Julie Gibbons
Jiansong Qin
Dongming Xie

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1692651

665 views

Original Research

Published on 23 Oct 2025

Metabolic engineering of Yarrowia lipolytica for enhanced microbial production of medium-chain α, ω-diols from alkanes via CRISPR-Cas9 mediated pathway optimization and P450 alkane monooxygenase overexpression

in Synthetic Biology

Ye Chan Kim
Won Yoon Hwan Choi
Eun-Jung Kim
Byung‐Gee Kim
Hyungdon Yun

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1695661

1,713 views

Original Research

Published on 13 Oct 2025

Targeted UDP-glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density

in Synthetic Biology

Marzia Rahimi
Lars K. Nielsen
Jesús Lavado-García

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1690203

1,468 views

Original Research

Published on 09 Oct 2025

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in Escherichia coli

in Synthetic Biology

Shimiao Chen
Bin Shan
Yican Luo
Ganhui Mo
Usman Rasheed
Lilan Lv
Xinyu Yang
Qinyu Lu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643833

1,328 views

Review

Published on 26 Sep 2025

Recent advances in Polygonaceae endophytes: diversity, secondary metabolites and biotechnological applications

in Synthetic Biology

Zhi-Min Chen
Rui-Qi Tang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1666908

1,652 views

Review

Published on 01 Sep 2025

Regeneration of cofactor NAD(P)+ with NAD(P)H oxidase for the production of value-added chemicals

in Synthetic Biology

Li-Jian Zhou
Shuai-Xi Long
Tong Huan
Yue Wu
Ye-Wang Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1650600

2,602 views

Original Research

Published on 29 Aug 2025

Enhancing lycopene production in Bacillus subtilis by overcoming a critical enzymatic bottleneck

in Synthetic Biology

Esha Rehman
Hawaibam Birla Singh
Minh Phuong Nguyen
Chonglong Wang
Sang-Hwal Yoon
Moonhyuk Kwon
Min-Kyoung Kang
Seon-Won Kim

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1670015

2,689 views

Original Research

Published on 29 Aug 2025

Live culture-based qPCR screening of Taq DNA polymerase variants for resistance to PCR inhibitors

in Synthetic Biology

Milko B. Kermekchiev
Zhian Zhang
Wayne M. Barnes

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1624735

2,047 views

Mini Review

Published on 28 Aug 2025

Yarrowia lipolytica as a promising cell factory for microbial production of value-added nutraceuticals

in Synthetic Biology

Soseon Lee
Ju Hyeon Lee
Hyun June Park
Seung-Ho Baek

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1673169

4,216 views

Editorial

Published on 29 Jul 2025

Editorial: Fusion proteins for the detection of pathogens or pathogen receptors

in Synthetic Biology

Roger M. Benoit

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1660729

1,670 views

Original Research

Published on 04 Jul 2025

A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions

in Synthetic Biology

Wataru Kitagawa
Kensuke Igarashi
Ryo Nagasawa
Shigeyuki Kakizawa
Mizuki Horino
Kosuke Fujishima
Toshiaki Fukui
Souichiro Kato

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1595440

2,730 views

Editorial

Published on 26 Jun 2025

Editorial: Microorganisms and microbial technologies for industry and environmental protection

in Synthetic Biology

Jianqiang Lin
Hongbo Hu
Dipesh Dhakal

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1637987

1,383 views

Original Research

Published on 26 Jun 2025

The effect on shikimate production by deleting iolR and metabolic engineering in PTS deficient Corynebacterium glutamicum strain

in Synthetic Biology

Rui Wen Ou
Charles A. Swofford
En-Ze Linda Zhong-Johnson
Cheng Li
Anthony J. Sinskey

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1616558

1,656 views