Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Mini Review

Published on 09 Oct 2025

Electrical stimulation: a missing key to promote maturation of human pluripotent stem cell-derived cardiomyocytes in three-dimensional cardiac tissues

in Tissue Engineering and Regenerative Medicine

Sem Sterckel
Robert Passier
José Manuel Rivera-Arbelaez

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1686342

3,080 views
2 citations

Original Research

Published on 08 Oct 2025

A novel cryoprecipitate-enriched PRP (Cryo-PRP) gel with enhanced mechanical strength and regenerative capacity accelerates enterocutaneous fistula healing

in Tissue Engineering and Regenerative Medicine

Zhang-Sheng Zhao
Zhen-Zhen Wang
Hua Ye
Xian-Lei Cai
Bin Hu
Qiu Han
You-Li Ma

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1668608

1,744 views

Original Research

Published on 07 Oct 2025

Biomechanical and biological features of hyaluronic acid in combination with chondroitin and platelet rich plasma for regenerative medicine applications

in Tissue Engineering and Regenerative Medicine

Valentina Vassallo
Celeste Di Meo
Antonella D’Agostino
Annalisa La Gatta
Donatella Cimini
Giuseppe Toro
Giovanni Iolascon
Maddalena Mastrogiacomo
Chiara Schiraldi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1607469

2,352 views
1 citation

Review

Published on 03 Oct 2025

The application of dental mesenchymal stem cells (DMSCs) in the repair of oral and maxillofacial defects

in Tissue Engineering and Regenerative Medicine

Yiqi Chen
Xikun Ma
Huaqing Mai
Pengyu Lai
Renlong Huang
Adili Alimujiang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1677422

3,283 views
1 citation

Systematic Review

Published on 01 Oct 2025

The impact of platelet-rich plasma injection on anterior cruciate ligament reconstruction: a systematic review and meta-analysis

in Tissue Engineering and Regenerative Medicine

Yiran Zhang
Zhikang Xiao
Zhe Fan
Yingxin Zhang
Jianzhong Xu
Kun Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1625271

3,036 views

Original Research

Published on 26 Sep 2025

In Vivo investigation of xenotransplanted human blood-derived scaffold into mice as a biodegradable construct for improvement of pelvic floor repair

in Tissue Engineering and Regenerative Medicine

Fariba Behnia-Willison
Pouria Aryan
Mojdeh Salehnia
Nadia Willison
Tran T. T. Nguyen
Nelson Tansu
Derek Abbott

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1627538

2,196 views

Original Research

Published on 24 Sep 2025

CGRP-dependent molecular signaling drives bone marrow stem cell osteogenesis in distraction osteogenesis

in Tissue Engineering and Regenerative Medicine

Yimurang Hamiti
Kai Liu
Sulong Wang
Xin Yang
Xiriaili Kadier
Aihemaitijiang Yusufu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1641476

2,896 views

Case Report

Published on 23 Sep 2025

A promising novel material-light-cured wound closure adhesives promote wound healing after pilonidal sinus open surgery: a Case Report

in Tissue Engineering and Regenerative Medicine

Jiachun Ni
Yiheng Yang
Qinyuan Liu
Yu Deng
Renjie Zhou
Linyong Zhu
Ying Li
Zhenyi Wang
Changpeng Han

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1635598

2,017 views

Systematic Review

Published on 23 Sep 2025

Properties of MSC populations enriched in CD146-expressing MSCs – a systematic review and meta-analysis of in vitro studies

in Tissue Engineering and Regenerative Medicine

Christian Behm
Katharina Schwarz
Oliwia Miłek
Andreas Krämmer
Oleh Andrukhov

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1668681

2,177 views
1 citation

Review

Published on 22 Sep 2025

Advances in human amniotic placenta membrane-derived mesenchymal stromal cells (hAMSCs) for regenerative medicine: enhancing therapeutic potential with biomaterials and scaffolds

in Tissue Engineering and Regenerative Medicine

Elvira H. de Laorden
Beatriz L. Rodilla
María Arroyo-Hernández
Maite Iglesias

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1590393

3,343 views
1 citation

Original Research

Published on 19 Sep 2025

Evaluation of in vitro and in vivo release of recombinant human nerve growth factor from bioengineered human stromal lenticule

in Tissue Engineering and Regenerative Medicine

Molly Tzu-Yu Lin
Yu-Chi Liu
Isabelle Xin Yu Lee
Domitilla Mandatori
Nicola Detta
Jing Ying Evelina Han
Letizia Pelusi
Leonardo Mastropasqua
Mario Nubile
Franca Cattani

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1588629

2,530 views

Review

Published on 18 Sep 2025

Current clinical and translational challenges in temporomandibular joint reconstruction

in Tissue Engineering and Regenerative Medicine

Helena Baecher
Bhagvat Maheta
Lisa-Marie Lottner
Adriana C. Panayi
Samuel Knoedler
Fernando Guastaldi
João F. Mano
Steffen Koerdt
Carsten Rendenbach
Max Heiland

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1590021

3,222 views
1 citation

Original Research

Published on 17 Sep 2025

Performance study of ZnO-TPU/CS bilayer composite electrospinning scaffold in skin wound healing

in Tissue Engineering and Regenerative Medicine

Jinlong Wang
Guoxing Huang
Quan Qin
Nianhua Dan
Xinlou Li
Kai Sun
Yuan Yang
Meng Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1636932

2,013 views
1 citation

Original Research

Published on 17 Sep 2025

Biosynthetic polyphosphate enhances osteogenesis of human periodontal ligament stem cells and promotes periodontal bone regeneration in a murine periodontal bone defect model

in Tissue Engineering and Regenerative Medicine

Jiaqi Chen
Dongying Lei
Xinyi Liu
Zipeng Chen
Jiaying Li
Liang Huang
Huifen Liu
Xuebin Yang
Wei Wei
Sijing Xie

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1672295

1,907 views

Review

Published on 16 Sep 2025

Advances in tissue engineering for the repair of growth plate injuries

in Tissue Engineering and Regenerative Medicine

Wenla Wang
Wenxiang Zeng
Qingyu Tu
Qing Li
Jindi Xu
Wei Zhuang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1608923

4,734 views
2 citations

Correction

Published on 16 Sep 2025

Correction: Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies

in Tissue Engineering and Regenerative Medicine

Andrea Dalmao-Fernandez
Aleksandra Aizenshtadt
Hege G. Bakke
Stefan Krauss
Arild C. Rustan
G. Hege Thoresen
Eili Tranheim Kase

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1687822

1,379 views

Original Research

Published on 11 Sep 2025

Refillable silicone pump with precise switching for timed therapeutic delivery

in Tissue Engineering and Regenerative Medicine

Naaz Thotathil
John J. Amante
Micah Wingell
Grace W. Hutter
Ultan Fallon
Yiling Fan
Keegan Mendez
Ellen T. Roche
Cathal J. Kearney

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1649771

2,848 views

Review

Published on 10 Sep 2025

Comparative review: clinical and pathological heterogeneity in knee versus temporomandibular joint osteoarthritis

in Tissue Engineering and Regenerative Medicine

Jiannan Zhao
Ruoyi Wang
Songsong Zhu
Zhen Li
Rong Ren
Nan Jiang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1684481

3,102 views
1 citation

Review

Published on 10 Sep 2025

Hyperbaric oxygen in combination with exosomes: a new strategy to promote tissue repair

in Tissue Engineering and Regenerative Medicine

Shengchao Zhang
Jiaqi Zhou
Jia Liu
Tong Li
Yong Liu
Yuling Gao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1639060

3,559 views

Original Research

Published on 10 Sep 2025

Novel platelet-rich plasma/ hyaluronic acid lyophilized formulations for wound healing applications

in Tissue Engineering and Regenerative Medicine

Antonella D’Agostino
Maria d’Agostino
Marta Nardini
Anita Muraglia
Celeste Di Meo
Maddalena Mastrogiacomo
Chiara Schiraldi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1619633

2,441 views

Review

Published on 09 Sep 2025

Recent advances in gradient biomimetic scaffolds for tendon-bone interface regeneration

in Tissue Engineering and Regenerative Medicine

Xianyan Xie
Yu Wang
Ziyan Li
Gaoyuan Yang
Guodong Cheng
Shuqi Qin
Huiguo Wang
Lin Zhu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1629816

5,283 views
5 citations

Systematic Review

Published on 05 Sep 2025

Hyaluronic acid as a biomaterial for dental pulp regeneration: a systematic review of preclinical studies

in Tissue Engineering and Regenerative Medicine

Azal Hadi Al-Masoody
Mahshid Hodjat
Tahereh Sadat Jafarzadeh Kashi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1661188

3,454 views
2 citations

Review

Published on 03 Sep 2025

Mitochondria and pluripotency: from established models to emerging roles in adult stem cells

in Tissue Engineering and Regenerative Medicine

Luminita Labusca
Camelia-Mihaela Zara-Danceanu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1654593

3,152 views
2 citations

Review

Published on 01 Sep 2025

Development of pathological skin models: from conventional techniques to 3D bioprinting

in Tissue Engineering and Regenerative Medicine

Maïté Rielland
Françoise Bernerd
Marie Camman
Xuezhu Tan
Nathalie Seyler

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1538774

3,298 views
1 citation

1,191 articles

articles

Electrical stimulation: a missing key to promote maturation of human pluripotent stem cell-derived cardiomyocytes in three-dimensional cardiac tissues

A novel cryoprecipitate-enriched PRP (Cryo-PRP) gel with enhanced mechanical strength and regenerative capacity accelerates enterocutaneous fistula healing

Biomechanical and biological features of hyaluronic acid in combination with chondroitin and platelet rich plasma for regenerative medicine applications

The application of dental mesenchymal stem cells (DMSCs) in the repair of oral and maxillofacial defects

The impact of platelet-rich plasma injection on anterior cruciate ligament reconstruction: a systematic review and meta-analysis

In Vivo investigation of xenotransplanted human blood-derived scaffold into mice as a biodegradable construct for improvement of pelvic floor repair

CGRP-dependent molecular signaling drives bone marrow stem cell osteogenesis in distraction osteogenesis

A promising novel material-light-cured wound closure adhesives promote wound healing after pilonidal sinus open surgery: a Case Report

Properties of MSC populations enriched in CD146-expressing MSCs – a systematic review and meta-analysis of in vitro studies

Advances in human amniotic placenta membrane-derived mesenchymal stromal cells (hAMSCs) for regenerative medicine: enhancing therapeutic potential with biomaterials and scaffolds

Evaluation of in vitro and in vivo release of recombinant human nerve growth factor from bioengineered human stromal lenticule

Current clinical and translational challenges in temporomandibular joint reconstruction

Performance study of ZnO-TPU/CS bilayer composite electrospinning scaffold in skin wound healing

Biosynthetic polyphosphate enhances osteogenesis of human periodontal ligament stem cells and promotes periodontal bone regeneration in a murine periodontal bone defect model

Advances in tissue engineering for the repair of growth plate injuries

Correction: Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies

Refillable silicone pump with precise switching for timed therapeutic delivery

Comparative review: clinical and pathological heterogeneity in knee versus temporomandibular joint osteoarthritis

Hyperbaric oxygen in combination with exosomes: a new strategy to promote tissue repair

Novel platelet-rich plasma/ hyaluronic acid lyophilized formulations for wound healing applications

Recent advances in gradient biomimetic scaffolds for tendon-bone interface regeneration

Hyaluronic acid as a biomaterial for dental pulp regeneration: a systematic review of preclinical studies

Mitochondria and pluripotency: from established models to emerging roles in adult stem cells

Development of pathological skin models: from conventional techniques to 3D bioprinting