Frontiers in Bioengineering and Biotechnology

Original Research

Published on 15 Oct 2025

Artificial cell vesicle-mediated delivery of Catharanthus roseus (L.) G. Don-derived vinca alkaloids for enhanced antitumor efficacy

Xiaodong Zhuang
Liangjiu Huang
Risheng Liu
Liwen Guan
Xingyue Fang
Ting Ma

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1703637

1,769 views

Original Research

Published on 15 Oct 2025

The influence of sex on lower limb biomechanical characteristics during single-leg drop landing in individuals with unilateral functional ankle instability

Huizi Cui
Zilong Wang
Minjie Lin
Tao Liu
Xiangdong Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1703251

1,759 views

Original Research

Published on 15 Oct 2025

Construction of bioactive nanocomposites from beta-sitosterol, fucoidan, chitosan, and silver nanoparticles for anticancer applications

Ahmed A. Tayel
Fatma K. Elagezy
Asmaa Abdella
Hend A. Gad
Mohamed E. El-Hefnawy
Sultan Alhayyani
Shaymaa W. El-Far

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1668888

1,724 views

Original Research

Published on 15 Oct 2025

Development and in-vitro validation of an intraoral wearable biofeedback system for bruxism management

Khalid A. Al-Hamad
Ashwaq Asiri
Ali M. Al-Qahtani
Saud Alotaibi
Abdullah Almalki

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1572970

2,446 views

Original Research

Published on 15 Oct 2025

Automated detection of pinworm parasite eggs using YOLO convolutional block attention module for enhanced microscopic image analysis

Esraa Hassan
Felwah Alqahtani
Samar Elbedwehy
Amira Samy Talaat

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1559987

2,561 views

Review

Published on 15 Oct 2025

Fibroblasts as key cellular targets in acupuncture therapy: a mechanistic perspective

Shi-Wei Tu
Jun Kawanokuchi
Ken Takagi
Yang-Yang Liu
Yan-Wei Li
Jun-Yi Li
Jia-Yi Tu
Ning Ma
Yi Guo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1662525

3,919 views

Original Research

Published on 14 Oct 2025

Biomechanical design of titanium-PEEK combined fusion cage based on PLIF surgical model

Chunsheng Liu
Yutang Xie
Xinrui Wu
Yanqin Wang
Yanru Xue
Pengcui Li
Wangping Duan
Xiaochun Wei
Weiyi Chen
Jinzhu Yin

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1671068

2,158 views

Original Research

Published on 14 Oct 2025

The inclination of the tibial component has an impact on fracture stability in unicompartmental knee arthroplasty: an artificial bone study

Mathis Wegner
Maximilian Bettendorff
Malte Bruhn
Jörg Bahr
Jürgen Carstensen
Leonard Siebert
Babak Moradi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1615216

1,570 views

Review

Published on 13 Oct 2025

Protein-based micro- and nano-transporters for gut microbiota modulators: advances in delivery strategies and gut health benefits

Mohammad Nasiruddin Rana
Md. Saifullah
Abu Saeid
Md. Murtuza Kamal
Xiangjing Gao
Xiangwei Gao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1706245

2,852 views
1 citation

Original Research

Published on 13 Oct 2025

Retinal features as predictive indicators for high myopia: insights from explainable multi-machine learning models

Haohan Zou
Jing Liu
Shenda Shi
Saiguang Ling
Qian Fan
Yan Huo
Zhou Dong
Guoge Han
Shengjin Wang
Yan Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1609639

2,019 views
1 citation

Editorial

Published on 13 Oct 2025

Editorial: Biomacromolecule systems for enhanced therapeutic delivery in medical implants

Joao Henrique Lopes
Nicolas Tabary
Jacobo Hernandez-Montelongo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1700914

1,233 views

Original Research

Published on 13 Oct 2025

Joint modeling and marker set selection significantly influence functional biomechanics in end-stage knee osteoarthritis: evidence from the sit-to-stand task

Giovanni Spallone
Letizia Mancini
Arianna Carnevale
Stefano Campi
Emiliano Schena
Pieter D’Hooghe
Michael T. Hirschmann
Rocco Papalia
Umile Giuseppe Longo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1677244

2,141 views

Original Research

Published on 13 Oct 2025

Targeted UDP-glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density

Marzia Rahimi
Lars K. Nielsen
Jesús Lavado-García

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1690203

2,218 views

Original Research

Published on 13 Oct 2025

FieldNA: a 3D printed vertical microfluidic device for portable nucleic acid isolation from olive oil samples

Vineet Penumarthy
Athanasia-Maria Dourou
Evangelia Lampropoulou
Stilianos Arhondakis
Ravi Prakash

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1646041

2,009 views

Review

Published on 10 Oct 2025

Extended view on the mechanobiology of fracture healing: interplay between mechanics and inflammation

Nico Gläser
Maria Schröder
Jan Barcik
Melanie Haffner-Luntzer
Esther Wehrle

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1652897

3,546 views
2 citations

Original Research

Published on 10 Oct 2025

Optimising tibial extension stem selection in total knee arthroplasty: the role of digital modelling

Mathieu Severyns
François Zot
Marc Gardegaront
Arnaud Germaneau
Tanguy Vendeuvre

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1634172

1,624 views

Original Research

Published on 09 Oct 2025

Pulsed electromagnetic fields preconditioned extracellular vesicles derived from mesenchymal stromal cells prevents necroptosis of osteoblasts in osteonecrosis of the femoral head rats

Xiao-Na Xiang
Jiang-Yin Zhang
Xiang-Xiu Wang
Hong-Chen He
Cheng-Qi He

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1655579

2,433 views

Review

Published on 09 Oct 2025

The role of collagen and collagen I/III ratio in pathological conditions: insights into molecular mechanisms and therapeutic approaches

Hemalatha Kanniyappan
Rathnayake A. Chathurika Rathnayake
Jude Osamor
Maria Islam
Rong R. Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1679625

5,770 views
1 citation

Original Research

Published on 09 Oct 2025

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in Escherichia coli

Shimiao Chen
Bin Shan
Yican Luo
Ganhui Mo
Usman Rasheed
Lilan Lv
Xinyu Yang
Qinyu Lu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643833

2,088 views

Mini Review

Published on 09 Oct 2025

Electrical stimulation: a missing key to promote maturation of human pluripotent stem cell-derived cardiomyocytes in three-dimensional cardiac tissues

Sem Sterckel
Robert Passier
José Manuel Rivera-Arbelaez

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1686342

3,053 views
2 citations

Original Research

Published on 09 Oct 2025

Osteogenic effects of electrophoretically deposited Sr-doped calcium silicate coatings on titanium

Zi Wang
Yimin Du
Shunlin Zhang
Hongliang Li
Jinghong Yang
Jiyuan Yan
Zhong Li
Jinhui Liu
Juncai Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1647759

1,831 views
1 citation

Original Research

Published on 08 Oct 2025

A novel cryoprecipitate-enriched PRP (Cryo-PRP) gel with enhanced mechanical strength and regenerative capacity accelerates enterocutaneous fistula healing

Zhang-Sheng Zhao
Zhen-Zhen Wang
Hua Ye
Xian-Lei Cai
Bin Hu
Qiu Han
You-Li Ma

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1668608

1,722 views

Original Research

Published on 07 Oct 2025

Epigallocatechin-gallate loaded BSA nanoparticles as innovative anti-inflammatory agents in immature macrophages

Simona Martano
Mariafrancesca Cascione
Livia Giotta
Loris Rizzello
Riccardo Di Corato
Stefano Leporatti
Rosaria Rinaldi
Valeria De Matteis

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1666492

2,040 views

Original Research

Published on 07 Oct 2025

Biomechanical and biological features of hyaluronic acid in combination with chondroitin and platelet rich plasma for regenerative medicine applications

Valentina Vassallo
Celeste Di Meo
Antonella D’Agostino
Annalisa La Gatta
Donatella Cimini
Giuseppe Toro
Giovanni Iolascon
Maddalena Mastrogiacomo
Chiara Schiraldi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1607469

2,331 views
1 citation

11,155 Publications

volumes

Volume 13 - 2025

Artificial cell vesicle-mediated delivery of Catharanthus roseus (L.) G. Don-derived vinca alkaloids for enhanced antitumor efficacy

The influence of sex on lower limb biomechanical characteristics during single-leg drop landing in individuals with unilateral functional ankle instability

Construction of bioactive nanocomposites from beta-sitosterol, fucoidan, chitosan, and silver nanoparticles for anticancer applications

Development and in-vitro validation of an intraoral wearable biofeedback system for bruxism management

Automated detection of pinworm parasite eggs using YOLO convolutional block attention module for enhanced microscopic image analysis

Fibroblasts as key cellular targets in acupuncture therapy: a mechanistic perspective

Biomechanical design of titanium-PEEK combined fusion cage based on PLIF surgical model

The inclination of the tibial component has an impact on fracture stability in unicompartmental knee arthroplasty: an artificial bone study

Protein-based micro- and nano-transporters for gut microbiota modulators: advances in delivery strategies and gut health benefits

Retinal features as predictive indicators for high myopia: insights from explainable multi-machine learning models

Editorial: Biomacromolecule systems for enhanced therapeutic delivery in medical implants

Joint modeling and marker set selection significantly influence functional biomechanics in end-stage knee osteoarthritis: evidence from the sit-to-stand task

Targeted UDP-glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density

FieldNA: a 3D printed vertical microfluidic device for portable nucleic acid isolation from olive oil samples

Extended view on the mechanobiology of fracture healing: interplay between mechanics and inflammation

Optimising tibial extension stem selection in total knee arthroplasty: the role of digital modelling

Pulsed electromagnetic fields preconditioned extracellular vesicles derived from mesenchymal stromal cells prevents necroptosis of osteoblasts in osteonecrosis of the femoral head rats

The role of collagen and collagen I/III ratio in pathological conditions: insights into molecular mechanisms and therapeutic approaches

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in Escherichia coli

Electrical stimulation: a missing key to promote maturation of human pluripotent stem cell-derived cardiomyocytes in three-dimensional cardiac tissues

Osteogenic effects of electrophoretically deposited Sr-doped calcium silicate coatings on titanium

A novel cryoprecipitate-enriched PRP (Cryo-PRP) gel with enhanced mechanical strength and regenerative capacity accelerates enterocutaneous fistula healing

Epigallocatechin-gallate loaded BSA nanoparticles as innovative anti-inflammatory agents in immature macrophages

Biomechanical and biological features of hyaluronic acid in combination with chondroitin and platelet rich plasma for regenerative medicine applications