Frontiers in Bioengineering and Biotechnology

Original Research

Published on 08 Jul 2025

Lung-resident SARS-CoV-2 peptide-specific immune responses in perfused 3D human lung explant models

Kayla F. Goliwas
Anthony M. Wood
Christopher S. Simmons
Rabisa Khan
Saad A. Khan
Yong Wang
Rekha Ramachandran
Joel L. Berry
Mohammad Athar
James A. Mobley

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1587080

2,495 views

Editorial

Published on 08 Jul 2025

Editorial: Nanodrug delivery strategies for enhanced cancer chemo-immunotherapy

Yufen Xiao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1653425

1,124 views

Original Research

Published on 08 Jul 2025

Biomechanical evaluation of percutaneous cement discoplasty combined with percutaneous vertebroplasty: a finite element analysis

Xu Zhou
Shenghua Qin
Chunhai Huang
Feiwen Li
Jin Liu
Ti Wu
Mingzheng Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1606709

1,743 views
1 citation

Review

Published on 07 Jul 2025

3D visualization of uterus and ovary: tissue clearing techniques and biomedical applications

Qiqi Liu
Zhuo Song
Simin Liu
Zirui Dong
Xi Zheng
Tak Yeung Leung
Xiaoyan Chen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1610539

4,523 views
1 citation

Original Research

Published on 07 Jul 2025

BDNF improves the survival of mesenchymal stem cells cultured on pre-structured gelatin material containing strontium and calcium phosphates for bone regeneration

Paul T. Itting
Benjamin Kruppke
Thomas Hanke
Vinu Vijayan
Christian Heiss
Katrin Susanne Lips

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1596846

1,929 views

Original Research

Published on 07 Jul 2025

Investigating the molecular mechanisms of the “Astragalus-Codonopsis” herb pair in treating diabetes: a network pharmacology and bioinformatics approach with molecular docking validation

Jinliang Yang
Mingyang Li
Ziyue Zhu
Fengling Han
Yanyan Ma
Jinbo Hou
Qingfeng Zhao
Hui Yuan
XiuMei Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1618575

3,599 views

Review

Published on 07 Jul 2025

Harnessing 3D cell models and high-resolution imaging to unveil the mechanisms of nanoparticle-mediated drug delivery

Alannah S. Chalkley
Maëva T. Lopez
Margaritha M. Mysior
Madeleen C. Brink
Suainibhe Kelly
Jeremy C. Simpson

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1606573

3,064 views
2 citations

Editorial

Published on 07 Jul 2025

Editorial: Harnessing nanotechnology for cancer treatment

Merlis P. Alvarez-Berrios
Chuang Liu
Jingjing Sun

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1651124

1,726 views

Original Research

Published on 07 Jul 2025

Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium

Ruoxuan Wu
Tianji Zhang
Siran Zhao
Marco Maccarana
Jin-Ping Li
Chao Li
Hui Cao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1597344

3,243 views

Original Research

Published on 04 Jul 2025

A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions

Wataru Kitagawa
Kensuke Igarashi
Ryo Nagasawa
Shigeyuki Kakizawa
Mizuki Horino
Kosuke Fujishima
Toshiaki Fukui
Souichiro Kato

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1595440

3,782 views

Original Research

Published on 04 Jul 2025

Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes: a proof of concept

Samuel Lukas Schneider
Abiram Gopalakrishnan
Misha Alexander Teale
Regine Eibl

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611703

3,110 views

Original Research

Published on 03 Jul 2025

Preparation and characterization of a GSH-responsive drug-loaded polymer nanoparticle/silk fibroin composite hydrogel

Yanjiu Li
Rong Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643800

1,815 views
2 citations

Original Research

Published on 03 Jul 2025

Biomechanical effects of orthodontic tooth movement on edentulous alveolar bone: a finite element analysis

Xiaoxu Wang
Jiaojiao Xue
Xiaoting Wang
Mingyue Fan

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1625027

3,090 views
4 citations

Original Research

Published on 03 Jul 2025

Impact of aortic morphology on VA-ECMO performance: a combined statistical shape modeling and CFD approach

Marilena Mazzoli
Emanuele Gasparotti
Emanuele Vignali
Dorela Haxhiademi
Simona Celi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1620897

1,832 views
2 citations

Review

Published on 02 Jul 2025

Challenges of using tissue engineering methods in the treatment of hypospadias

P. Wilczek
D. Bociaga
M. Krakos
A. Wierzbicka

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611508

3,191 views

Original Research

Published on 02 Jul 2025

High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network

Weiwei Zhang
Xinyu Li
Qiao Liu
Xiangyang Zheng
Yisu Ge
Xiaotian Pan
Yu Zhou

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1583416

4,085 views
4 citations

Systematic Review

Published on 02 Jul 2025

Meta-analysis of the effects of calcium phosphate bone tissue engineering scaffolds on orthodontic bone augmentation and tooth movement

Jiawen Zhao
Xuefei Liu
Qi Zhang
Yinan Jin
Gang Zhao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1553822

2,480 views
1 citation

Original Research

Published on 01 Jul 2025

Quantitative and qualitative investigation of shunt failure in an in vitro hemorrhagic hydrocephalus model

Shaheer Ajaz
Ahmad Faryami
Ayman Suhrawardy
Carolyn A. Harris

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1591952

1,896 views

Methods

Published on 01 Jul 2025

Cyclic testing reliability analysis on a novel light-curable bone fixation technique

Paula M. N. Cameron
Daniel J. Hutchinson
Micheal Malkoch
Peter Varga
Peter Schwarzenberg

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1515319

1,546 views

Systematic Review

Published on 01 Jul 2025

The current status of nano-hydrogel preparations for osteochondral repair: Systematic Review

Abebe Feyissa Amhare
Lichun Qiao
Huan Deng
Jinyan Lin
Jun Wang
Wei Wang
Jing Han

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1611522

3,589 views
3 citations

Original Research

Published on 01 Jul 2025

Biomechanical and clinical comparison of different prosthetic in reconstruction following total en bloc spondylectomy in the thoracolumbar spine: based on finite element analysis and clinical data

Zhangui Gu
Long Ma
Qiang Liu
Kun Wang
Zongqiang Yang
Ningkui Niu
Jiandang Shi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1573086

1,879 views
1 citation

Original Research

Published on 30 Jun 2025

Low-intensity ultrasound lysis of amyloid microclots in a lab-on-chip model

Reza Rasouli
Brad Hartl
Soren D. Konecky

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1604447

8,639 views
5 citations

Original Research

Published on 30 Jun 2025

Novel stereo DIC characterisation of microneedle and hypodermic needle insertion

Megan McNamee
Thomas Pritchard
Jacob Mitchell
Chris Bolton
Kerry Roberts
Owen Guy
Huma Ashraf
Hari Arora

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1580464

2,358 views

Original Research

Published on 30 Jun 2025

High-speed electro-optic modulator with group velocity matching on silicon substrate

Yingbo Liu
Haiou Li
Yue Li
Haisheng Li
Yuxiang Hao
Liangpeng Qin
Jiayu Yang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1626017

2,668 views
2 citations

11,173 Publications

volumes

Volume 13 - 2025

Lung-resident SARS-CoV-2 peptide-specific immune responses in perfused 3D human lung explant models

Editorial: Nanodrug delivery strategies for enhanced cancer chemo-immunotherapy

Biomechanical evaluation of percutaneous cement discoplasty combined with percutaneous vertebroplasty: a finite element analysis

3D visualization of uterus and ovary: tissue clearing techniques and biomedical applications

BDNF improves the survival of mesenchymal stem cells cultured on pre-structured gelatin material containing strontium and calcium phosphates for bone regeneration

Investigating the molecular mechanisms of the “Astragalus-Codonopsis” herb pair in treating diabetes: a network pharmacology and bioinformatics approach with molecular docking validation

Harnessing 3D cell models and high-resolution imaging to unveil the mechanisms of nanoparticle-mediated drug delivery

Editorial: Harnessing nanotechnology for cancer treatment

Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium

A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions

Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes: a proof of concept

Preparation and characterization of a GSH-responsive drug-loaded polymer nanoparticle/silk fibroin composite hydrogel

Biomechanical effects of orthodontic tooth movement on edentulous alveolar bone: a finite element analysis

Impact of aortic morphology on VA-ECMO performance: a combined statistical shape modeling and CFD approach

Challenges of using tissue engineering methods in the treatment of hypospadias

High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network

Meta-analysis of the effects of calcium phosphate bone tissue engineering scaffolds on orthodontic bone augmentation and tooth movement

Quantitative and qualitative investigation of shunt failure in an in vitro hemorrhagic hydrocephalus model

Cyclic testing reliability analysis on a novel light-curable bone fixation technique

The current status of nano-hydrogel preparations for osteochondral repair: Systematic Review

Biomechanical and clinical comparison of different prosthetic in reconstruction following total en bloc spondylectomy in the thoracolumbar spine: based on finite element analysis and clinical data

Low-intensity ultrasound lysis of amyloid microclots in a lab-on-chip model

Novel stereo DIC characterisation of microneedle and hypodermic needle insertion

High-speed electro-optic modulator with group velocity matching on silicon substrate