Frontiers in Bioinformatics

Original Research

Published on 13 May 2025

Exploiting subtractive genomics to identify novel drug targets and new immunogenic candidates against Bordetella pertussis: an in silico study

in Drug Discovery in Bioinformatics

Mahshid Khazani Asforooshani
Narjes Noori Goodarzi
Behzad Shahbazi
Nayereh Rezaie Rahimi
Kimia Mahdavian
Mahdi Rohani
Farzad Badmasti

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1570054

1,225 views

Technology and Code

Published on 08 May 2025

micRoclean: an R package for decontaminating low-biomass 16S-rRNA microbiome data

in Genomic Analysis

Rachel Griffard-Smith
Emily Schueddig
Diane E. Mahoney
Prabhakar Chalise
Devin C. Koestler
Dong Pei

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1556361

1,050 views

Perspective

Published on 08 May 2025

Structural biology meets typography: using protein structures to inspire creative expression and connect diverse audiences

in Data Visualization

Leonora Martínez-Núñez

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1589122

1,176 views

Original Research

Published on 06 May 2025

Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques

in Drug Discovery in Bioinformatics

Behnam Hasannejad-Asl
Farkhondeh Pooresmaeil
Sareh azadi
Ali Najafi
Ali Esmaeili
Saeid Bagheri-Mohammadi
Bahram Kazemi

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1570101

1,878 views

Original Research

Published on 06 May 2025

Tumor tissue-of-origin classification using miRNA-mRNA-lncRNA interaction networks and machine learning methods

in RNA Bioinformatics

Ankita Lawarde
Masuma Khatun
Prakash Lingasamy
Andres Salumets
Vijayachitra Modhukur

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1571476

2,150 views

Brief Research Report

Published on 06 May 2025

pubCounteR: an R package for interrogating published literature for experimentally-derived gene lists within a user-defined biological context

in Data Visualization

Marina Leer
George A. Soultoukis
Markus Jähnert
Masoome Oveisi
Dirk Walther
Tim J. Schulz

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1523184

1,037 views

Methods

Published on 30 Apr 2025

Integrating phylogenies with chronology to assemble the tree of life

in Evolutionary Bioinformatics

Jose Barba-Montoya
Jack M. Craig
Sudhir Kumar

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1571568

1,125 views

Review

Published on 23 Apr 2025

Artificial intelligence in variant calling: a review

in Genomic Analysis

Omar Abdelwahab
Davoud Torkamaneh

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1574359

3,356 views
2 citations

Mini Review

Published on 17 Apr 2025

Primer on machine learning applications in brain immunology

in Single Cell Bioinformatics

Niklas Binder
Ashkan Khavaran
Roman Sankowski

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1554010

1,659 views

Original Research

Published on 17 Apr 2025

Biomarker-driven drug repurposing for NAFLD-associated hepatocellular carcinoma using machine learning integrated ensemble feature selection

in Drug Discovery in Bioinformatics

Subhajit Ghosh
Sukhen Das Mandal
Subarna Thakur

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1522401

2,191 views

Original Research

Published on 17 Apr 2025

Classification of collagen remodeling in asthma using second-harmonic generation imaging, supervised machine learning and texture-based analysis

in Computational BioImaging

Natasha N. Kunchur
Joshua J. A. Poole
Jesse Levine
Tillie-Louise Hackett
Rebecca Thornhill
Leila B. Mostaço-Guidolin

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1539936

1,300 views

Original Research

Published on 16 Apr 2025

Genomic analysis of Listeria monocytogenes strains from dairy products in Ethiopia

in Genomic Analysis

Mebrie Zemene Kinde
Bizuayehu Kerisew
Tegegne Eshetu
Abebe Tesfaye Gessese

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1572241

2,024 views

Original Research

Published on 15 Apr 2025

Identification of novel drug targets and small molecule discovery for MRSA infections

in Drug Discovery in Bioinformatics

Nandha Kumar Subramani
Subhashree Venugopal

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1562596

1,692 views

Original Research

Published on 14 Apr 2025

Using AlphaFold-Multimer to study novel protein-protein interactions of predation essential hypothetical proteins in Bdellovibrio

in Protein Bioinformatics

Ibukun John Abulude
Isabel Cristina Rodríguez Luna
Alejandro Sánchez Varela
Andrew Camilli
Daniel E. Kadouri
Xianwu Guo

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1566486

2,188 views

Perspective

Published on 09 Apr 2025

A cost and community perspective on the barriers to microbiome data reuse

in Genomic Analysis

Julia M. Kelliher
Leah Y. D. Johnson
Francisca E. Rodriguez
Jaclyn K. Saunders
Marie E. Kroeger
Buck Hanson
Aaron J. Robinson
Winston E. Anthony
Marc W. Van Goethem
Anders Kiledal

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1585717

2,417 views

Original Research

Published on 09 Apr 2025

Transcripts derived from AmnSINE1 repetitive sequences are depleted in the cortex of autism spectrum disorder patients

in Evolutionary Bioinformatics

Nicolina Sciaraffa
Daniele Santoni
Andrea Li Greci
Swonild Ilenia Genovese
Claudia Coronnello
Walter Arancio

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1532981

1,132 views