Frontiers in Cardiovascular Medicine | Cardiovascular Genetics and Systems Medicine

Original Research

Published on 15 Jul 2021

Contribution of Congenital Heart Disorders Associated With Copy Number Variants in Mediating Risk for Brain Developmental Disorders: Evidence From 20-Year Retrospective Cohort Study

in Cardiovascular Genetics and Systems Medicine

Luke Dowden
David Tucker
Sian Morgan
Orhan Uzun
Yasir Ahmed Syed

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.655463

3,517 views
9 citations

Original Research

Published on 12 Jul 2021

WNT3A rs752107(C > T) Polymorphism Is Associated With an Increased Risk of Essential Hypertension and Related Cardiovascular Diseases

in Cardiovascular Genetics and Systems Medicine

Huan Ren
Jian-Quan Luo
Fan Ouyang
Li Cheng
Xiao-Ping Chen
Hong-Hao Zhou
Wei-Hua Huang
Wei Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.675222

4,460 views
13 citations

Original Research

Published on 02 Jul 2021

Analysis of Hub Genes and the Mechanism of Immune Infiltration in Stanford Type a Aortic Dissection

in Cardiovascular Genetics and Systems Medicine

Haoyu Gao
Xiaogang Sun
Yanxiang Liu
Shenghua Liang
Bowen Zhang
Luchen Wang
Jie Ren

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.680065

9,025 views
28 citations

Case Report

Published on 01 Jul 2021

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

in Cardiovascular Genetics and Systems Medicine

Paula Morlanes-Gracia
Guido Antoniutti
Jorge Alvarez-Rubio
Laura Torres-Juan
Damian Heine-Suñer
Tomás Ripoll-Vera

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.691203

6,488 views
11 citations

Original Research

Published on 28 Jun 2021

Effect of Cytochrome P450 Family 2 Subfamily R Member 1 Variants on the Predisposition of Coronary Heart Disease in the Chinese Han Population

in Cardiovascular Genetics and Systems Medicine

Qi Wang
Zhen Lin
Hairong Chen
Tianyi Ma
Biyun Pan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.652729

2,907 views
5 citations

Original Research

Published on 23 Jun 2021

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

in Cardiovascular Genetics and Systems Medicine

Kenji Onoue
Hiroko Wakimoto
Jiangming Jiang
Michael Parfenov
Steven DePalma
David Conner
Joshua Gorham
David McKean
Jonathan G. Seidman
Christine E. Seidman

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.639148

6,338 views
10 citations

Opinion

Published on 21 Jun 2021

Further Considerations in Childhood-Onset Hypertrophic Cardiomyopathy Genetic Testing

in Cardiovascular Genetics and Systems Medicine

Michelle M. Monasky
Emanuele Micaglio
Silvia Ignaccolo
Carlo Pappone

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.698078

2,130 views

Original Research

Published on 11 Jun 2021

Cardiac Dysfunction in a Mouse Vascular Dementia Model of Bilateral Common Carotid Artery Stenosis

in Cardiovascular Genetics and Systems Medicine

Lulu An
Michael Chopp
Alex Zacharek
Yi Shen
Zhili Chen
Yu Qian
Wei Li
Julie Landschoot-Ward
Zhongwu Liu
Poornima Venkat

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.681572

9,438 views
12 citations

Original Research

Published on 31 May 2021

A Functional Indel Polymorphism Within MIR155HG Is Associated With Sudden Cardiac Death Risk in a Chinese Population

in Cardiovascular Genetics and Systems Medicine

Qing Zhang
Huan Yu
Zhenzhen Yang
Lijuan Li
Yan He
Shaohua Zhu
Chengtao Li
Suhua Zhang
Bin Luo
Yuzhen Gao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.671168

3,607 views
5 citations

Original Research

Published on 31 May 2021

Identification of Potential miRNA-mRNA Regulatory Network Contributing to Hypertrophic Cardiomyopathy (HCM)

in Cardiovascular Genetics and Systems Medicine

Lin Wang
Fengmin Lu
Jing Xu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.660372

5,652 views
13 citations

Original Research

Published on 28 May 2021

Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta

in Cardiovascular Genetics and Systems Medicine

Xianwu Zhou
Zerui Chen
Jianrong Zhou
Yaorong Liu
Ruixin Fan
Tucheng Sun

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.627380

7,165 views
23 citations

Original Research

Published on 26 May 2021

Mutant Single Nucleotide Polymorphism rs189037 in Ataxia-Telangiectasia Mutated Gene Is Significantly Associated With Ventricular Wall Thickness and Human Lifespan

in Cardiovascular Genetics and Systems Medicine

Shihui Fu
Jianqiu Hu
Xiaoping Chen
Bo Li
Hongjuan Shun
Juelin Deng
Yujie Zhang
Yao Yao
Yali Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.658908

2,893 views
15 citations

Original Research

Published on 21 May 2021

Knockdown of lncRNA ENST00000609755.1 Confers Protection Against Early oxLDL-Induced Coronary Heart Disease

in Cardiovascular Genetics and Systems Medicine

Yi Sun
Shuna Huang
Chunyu Wan
Qishuang Ruan
Xiaoxu Xie
Donghong Wei
Guobo Li
Shaowei Lin
Huangyuan Li
Siying Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.650212

3,414 views
5 citations

Original Research

Published on 20 May 2021

Phenotypic Variability of a Pathogenic PKP2 Mutation in an Italian Family Affected by Arrhythmogenic Cardiomyopathy and Juvenile Sudden Death: Considerations From Molecular Autopsy to Sport Restriction

in Cardiovascular Genetics and Systems Medicine

Maria Pia Leone
Pietro Palumbo
Johan Saenen
Sandra Mastroianno
Stefano Castellana
Cesare Amico
Tommaso Mazza
Domenico Rosario Potenza
Antonio Petracca
Marco Castori

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.635141

6,009 views
6 citations

Original Research

Published on 20 May 2021

Regulatory T Cell-Related Gene Biomarkers in the Deterioration of Atherosclerosis

in Cardiovascular Genetics and Systems Medicine

Meng Xia
Qingmeng Wu
Pengfei Chen
Cheng Qian

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.661709

7,039 views
23 citations

Original Research

Published on 10 May 2021

Does Chronic Intestinal Inflammation Promote Atrial Fibrillation: A Mendelian Randomization Study With Populations of European Ancestry

in Cardiovascular Genetics and Systems Medicine

LaiTe Chen
ChenYang Jiang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.641291

6,775 views
4 citations

Review

Published on 10 May 2021

Panomics: New Databases for Advancing Cardiology

in Cardiovascular Genetics and Systems Medicine

Dara Vakili
Dina Radenkovic
Shreya Chawla
Deepak L. Bhatt

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.587768

10,658 views
5 citations

Review

Published on 07 May 2021

Role of N6-Methyladenosine RNA Modification in Cardiovascular Disease

in Cardiovascular Genetics and Systems Medicine

Dandan Song
Jianhua Hou
Junduo Wu
Junnan Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.659628

5,271 views
8 citations

Original Research

Published on 05 May 2021

Essential Genes and MiRNA–mRNA Network Contributing to the Pathogenesis of Idiopathic Pulmonary Arterial Hypertension

in Cardiovascular Genetics and Systems Medicine

Shengyu Hao
Pan Jiang
Liang Xie
Guiling Xiang
Zilong Liu
Weiping Hu
Qinhan Wu
Liyan Jiang
Yi Xiao
Shanqun Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.627873

6,627 views
9 citations

Original Research

Published on 30 Apr 2021

Clinical Significance of Variants in the TTN Gene in a Large Cohort of Patients With Sporadic Dilated Cardiomyopathy

in Cardiovascular Genetics and Systems Medicine

Lei Xiao
Chenze Li
Yang Sun
Yanghui Chen
Haoran Wei
Dong Hu
Ting Yu
Xianqing Li
Li Jin
Leming Shi

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.657689

16,424 views
21 citations

Original Research

Published on 26 Apr 2021

Resistin-Like Molecule α Dysregulates Cardiac Bioenergetics in Neonatal Rat Cardiomyocytes

in Cardiovascular Genetics and Systems Medicine

Bingdong Tao
Santosh Kumar
Jose Gomez-Arroyo
Chunling Fan
Ailan Zhang
John Skinner
Elizabeth Hunter
Kazuyo Yamaji-Kegan
Idris Samad
Alexander T. Hillel

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.574708

5,556 views
5 citations

Original Research

Published on 26 Apr 2021

Profiling of miR-205/P4HA3 Following Angiotensin II-Induced Atrial Fibrosis: Implications for Atrial Fibrillation

in Cardiovascular Genetics and Systems Medicine

Zezhou Xiao
Desai Pavan Kumar Reddy
Chuqing Xue
Ximao Liu
Xiong Chen
Jiale Li
Xiao Ling
Shaoyi Zheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.609300

5,904 views
22 citations

Original Research

Published on 21 Apr 2021

circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p

in Cardiovascular Genetics and Systems Medicine

Haoyuan Zheng
Lin Shi
Changci Tong
Yunen Liu
Mingxiao Hou

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.656093

10,838 views
74 citations

Original Research

Published on 20 Apr 2021

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

in Cardiovascular Genetics and Systems Medicine

Danielle van Keulen
Ian D. van Koeverden
Arjan Boltjes
Hans M. G. Princen
Alain J. van Gool
Gert J. de Borst
Folkert W. Asselbergs
Dennie Tempel
Gerard Pasterkamp
Sander W. van der Laan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.658915

6,372 views
9 citations

506 articles

articles

Contribution of Congenital Heart Disorders Associated With Copy Number Variants in Mediating Risk for Brain Developmental Disorders: Evidence From 20-Year Retrospective Cohort Study

WNT3A rs752107(C > T) Polymorphism Is Associated With an Increased Risk of Essential Hypertension and Related Cardiovascular Diseases

Analysis of Hub Genes and the Mechanism of Immune Infiltration in Stanford Type a Aortic Dissection

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

Effect of Cytochrome P450 Family 2 Subfamily R Member 1 Variants on the Predisposition of Coronary Heart Disease in the Chinese Han Population

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

Further Considerations in Childhood-Onset Hypertrophic Cardiomyopathy Genetic Testing

Cardiac Dysfunction in a Mouse Vascular Dementia Model of Bilateral Common Carotid Artery Stenosis

A Functional Indel Polymorphism Within MIR155HG Is Associated With Sudden Cardiac Death Risk in a Chinese Population

Identification of Potential miRNA-mRNA Regulatory Network Contributing to Hypertrophic Cardiomyopathy (HCM)

Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta

Mutant Single Nucleotide Polymorphism rs189037 in Ataxia-Telangiectasia Mutated Gene Is Significantly Associated With Ventricular Wall Thickness and Human Lifespan

Knockdown of lncRNA ENST00000609755.1 Confers Protection Against Early oxLDL-Induced Coronary Heart Disease

Phenotypic Variability of a Pathogenic PKP2 Mutation in an Italian Family Affected by Arrhythmogenic Cardiomyopathy and Juvenile Sudden Death: Considerations From Molecular Autopsy to Sport Restriction

Regulatory T Cell-Related Gene Biomarkers in the Deterioration of Atherosclerosis

Does Chronic Intestinal Inflammation Promote Atrial Fibrillation: A Mendelian Randomization Study With Populations of European Ancestry

Panomics: New Databases for Advancing Cardiology

Role of N6-Methyladenosine RNA Modification in Cardiovascular Disease

Essential Genes and MiRNA–mRNA Network Contributing to the Pathogenesis of Idiopathic Pulmonary Arterial Hypertension

Clinical Significance of Variants in the TTN Gene in a Large Cohort of Patients With Sporadic Dilated Cardiomyopathy

Resistin-Like Molecule α Dysregulates Cardiac Bioenergetics in Neonatal Rat Cardiomyocytes

Profiling of miR-205/P4HA3 Following Angiotensin II-Induced Atrial Fibrosis: Implications for Atrial Fibrillation

circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans