Frontiers in Cardiovascular Medicine | Cardiovascular Pharmacology and Drug Discovery

Original Research

Accepted on 09 Apr 2025

From Knowledge Silos to Integrated Insights: Building a Cardiovascular Medication Knowledge Graph for Enhanced Medication Knowledge Retrieval, Relationship Discovery, and Reasoning

in Cardiovascular Pharmacology and Drug Discovery

Hongzhen Cui
Xiaoyue Zhu
Wei Zhang
Meihua Piao
Yunfeng Peng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1526247

184 views

Original Research

Accepted on 09 Apr 2025

Treatment Adherence, Persistence, and Effectiveness of Fixed Dose Combination versus Free Combination Therapy of Rosuvastatin-Ezetimibe as a Lipid-Lowering Therapy

in Cardiovascular Pharmacology and Drug Discovery

Mihail Samnaliev
Irfan Khan
Praveen Potukuchi
Kelly Lee
Genevieve Garon
Charlie Nicholls

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1461416

357 views

Original Research

Accepted on 08 Apr 2025

Adverse Events Associated with Amlodipine: A Pharmacovigilance Study Using the FDA Adverse Event Reporting System

in Cardiovascular Pharmacology and Drug Discovery

Xingwei Di
Qian Zhong
Jiazhen Jiang
Xinyu Zhou
Lisi Zhou
Jiyuan Zheng
Bingshuo Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1504671

110 views

Original Research

Accepted on 31 Mar 2025

Mechanism of Ershen Zhenwu Decoction in Ameliorating Chronic Heart Failure via JNK/MAPK-Regulated Apoptosis: Insights from Network Pharmacology and Experimental Validation

in Cardiovascular Pharmacology and Drug Discovery

Yulong Liu
Xinyue Wang
Maomao Zhang
Dan Cheng
Zhenpeng Zhu
Lan Ge
Xiaoyu Cheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1561963

Original Research

Accepted on 27 Mar 2025

Integrating Network Pharmacology and Experimental Validation to Investigate the Mechanism of Gualou Xiebai Banxia Decoction Against Myocardial Ischemia

in Cardiovascular Pharmacology and Drug Discovery

Wanjun Zhu
Ping Shao
Ying Ren
Wenxuan Liu
Xiaorui Han
Kexin Zeng
Chunmei Dai
Feifei Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1512791

Brief Research Report

Published on 14 Mar 2025

Cross-Sectional analysis of demographic and clinical characteristics of patients in the United States using icosapent ethyl

in Cardiovascular Pharmacology and Drug Discovery

Peter P. Toth
John R. Nelson
Handrean Soran
Om P. Ganda
Nathan D. Wong
Hakima Hannachi
David Abrahamson
Josh Hartman
Sierra Luciano
Sephy Philip

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1411233

700 views

Original Research

Published on 20 Feb 2025

A comprehensive study on the impact of Ligustrum vicaryi L. fruit polysaccharide on myocardial fibrosis through animal experiments, network pharmacology and molecular docking

in Cardiovascular Pharmacology and Drug Discovery

Shuling Liu
Meifang Liu
Jianan Wang
Ruixue Rong
Yanwei Gao
Xiaoqi Li
Xin Liu
Shaojian Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1470761

1,027 views

Original Research

Published on 13 Feb 2025

Network pharmacology to unveil the blood components and mechanisms of Tongmai Yangxin Pills in treating elderly coronary heart disease

in Cardiovascular Pharmacology and Drug Discovery

Yue Zhang
Chao-Hui Li
Yi-Zhi Yan
Jie-Yun Lin
Shan-Shan Zhu
Si-Jie Tan
Peng Zeng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1475546

1,460 views
1 citation

Systematic Review

Published on 15 Jan 2025

Efficacy and safety of cardiac myosin inhibitors for symptomatic hypertrophic cardiomyopathy: a meta-analysis of randomized controlled trials

in Cardiovascular Pharmacology and Drug Discovery

Anas Abunada
Madiha Shah
Ateesh Kumar
Syeda Lamiya Mir
Dinesh Kumar
Saboor Ahmed
Muhammad Tanzeel
Vikash Kumar
Aashish Meghjiani
Muhammad Basit Ali Siddiqui

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1477487

1,622 views

Review

Published on 15 Jan 2025

Chinese and western medicine treatment of myocardial fibrosis drugs

in Cardiovascular Pharmacology and Drug Discovery

Yuxi Zhu
Fangmei Zhang
Zhongcheng Li
Yu Zhou
Yi Shu
Jian Ruan
Guo Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1477601

1,336 views

Systematic Review

Published on 14 Jan 2025

Comparative efficacy of different drugs in acute heart failure with renal dysfunction: a systematic review and network meta-analysis

in Cardiovascular Pharmacology and Drug Discovery

Qianyu Lv
Qian Wu
Yingtian Yang
Lanlan Li
Xuejiao Ye
Shihan Wang
Yanfei Lv
Manshi Wang
Yushan Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1444068

1,059 views

Editorial

Published on 07 Jan 2025

Editorial: Novel treatments for cardiovascular diseases by targeting inflammation, oxidative stress, and cell death

in Cardiovascular Pharmacology and Drug Discovery

Dong Fan
Li Wang
Abhijit Chakraborty
Cheng-Lin Zhang
Feng Hua Yang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1538222

824 views

Original Research

Published on 06 Jan 2025

Effects of different doses of remimazolam on the quality of sedation and cardiac function in elderly patients: a double-blind randomised controlled study

in Cardiovascular Pharmacology and Drug Discovery

Liu Minghong
Qizhu Feng
Huichun Chen
Ju Li
Jun Shi

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1453608

900 views

Review

Published on 03 Dec 2024

Traditional Chinese medicine for cardiovascular disease: efficacy and safety

in Cardiovascular Pharmacology and Drug Discovery

Youwei Lin
Yuanshan Han
Yuhong Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1419169

1,534 views

Systematic Review

Published on 22 Nov 2024

Exploring research trends and hotspots on PCSK9 inhibitor studies: a bibliometric and visual analysis spanning 2007 to 2023

in Cardiovascular Pharmacology and Drug Discovery

Ping Lai
Shuquan Xu
Ziyou Liu
Jiayuan Ling
Kejun Tian
Jianwei Yan
Dong Chen
Yiming Zhong
Jinhua Xue

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1474472

1,830 views

Original Research

Published on 29 Oct 2024

Metabolomics revealed pharmacodynamic effects of aspirin and indobufen in patients after percutaneous transluminal angioplasty surgery

in Cardiovascular Pharmacology and Drug Discovery

Shaobo Sun
Kang Xun
Damei Li
Renjie Bao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1433643

700 views