Frontiers in Cardiovascular Medicine | Cardiovascular Pharmacology and Drug Discovery

Original Research

Published on 04 Jul 2025

Herb pair of Astragali Radix-Descurainiae Semen attenuate heart failure through the myosin VI-Tom1 complex mediated autophagy

in Cardiovascular Pharmacology and Drug Discovery

Mengyue Wang
Songlin Ni
Tong Wang
Mo Sun
Qiaolan Wu
Xiaolin Wu
Guangying Lu
Peiwei Su
Zu Gao
Qian Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1599746

299 views

Review

Published on 01 Jul 2025

The therapeutic effects of natural organosulfur compounds on atherosclerosis and their potential mechanisms: a comprehensive review

in Cardiovascular Pharmacology and Drug Discovery

Yuanyuan Tang
De Lv
Yijing Tao
Juan Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1599154

467 views

Original Research

Published on 30 Jun 2025

CLU, FOS, and CXCL8 as diagnostic biomarkers for heart failure progression post-acute myocardial infarction: an integrated RNA-Seq and multi-machine learning study

in Cardiovascular Pharmacology and Drug Discovery

Jingjing Wei
Peng Yu
Yucai Hu
Lijie Qiao
Bin Li
Haitao Li
Shiyang Xie
Zhengwei Dong
Aolong Wang
Yilin Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1611668

367 views

Brief Research Report

Published on 30 Jun 2025

Clinical outcomes of pharmacological therapies for heart failure in Black vs. White populations: a meta-analysis of randomized controlled trials of heart failure treatment

in Cardiovascular Pharmacology and Drug Discovery

Yujia Li
Huilin Tang
Wenxi Huang
Wei-Han Chen
Shao-Hsuan Chang
Jiang Bian
Mustafa M. Ahmed
Stephen E. Kimmel
Jingchuan Guo

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1482311

374 views

Systematic Review

Accepted on 27 Jun 2025

A Systematic Review and Network Meta-Analysis of Cardiovascular Safety of Benzbromarone compared to Febuxostat and Allopurinol in Patients with Gout

in Cardiovascular Pharmacology and Drug Discovery

Ting-Syuan Lin
Yen-Liang Lin
Chiu-Hao Hsu
Song-Chou Hsieh
Wen-Yi Shau
Wei-Shiung Yang
Chi-Ling Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1541307

144 views

Correction

Published on 27 Jun 2025

Correction: Adverse events associated with amlodipine: a pharmacovigilance study using the FDA adverse event reporting system

in Cardiovascular Pharmacology and Drug Discovery

Jiazhen Jiang
Qian Zhong
Xinyu Zhou
Lisi Zhou
Jiyuan Zheng
Bingshuo Liu
Xingwei Di

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1636315

274 views

Editorial

Published on 27 Jun 2025

Editorial: Therapeutic strategies to lower residual dyslipidemic CV risk beyond LDL-C and statins

in Cardiovascular Pharmacology and Drug Discovery

Raffaele De Caterina
Matthew Budoff
William E. Boden

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1597062

527 views

Review

Accepted on 26 Jun 2025

The Role of Nrf2 Signaling Pathway in Diabetic Cardiomyopathy: From Pathogenesis to Traditional Chinese Medicine Intervention

in Cardiovascular Pharmacology and Drug Discovery

Huixian Gu
Junchang Liu
Jiang Jie
Hongyan Ma
Siyu Wu
Longfei Sun
Lan Yao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1492499

191 views

Systematic Review

Published on 26 May 2025

Methods and validity indicators for measuring adherence and persistence to aspirin in secondary cardiovascular prevention: a systematic review

in Cardiovascular Pharmacology and Drug Discovery

Rauf Nouni-García
Elisabeth Ramirez-Familia
Adriana López-Pineda
Amanda Esquerdo-Arroyo
Álvaro Carbonell-Soliva
María Martínez-Muñóz
Antonio F. Compañ Rosique
Jose A. Quesada
Concepción Carratalá-Munuera
Vicente F. Gil-Guillén

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1570331

1,048 views

Review

Published on 26 May 2025

Chinese medicine targets cellular autophagy against cardiovascular diseases: research progress and future prospects

in Cardiovascular Pharmacology and Drug Discovery

Zhengyu Chen
Jinjin Dou
Xiwu Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1585407

817 views

Original Research

Published on 23 May 2025

Yellow Wine Polyphenolic Compounds protect against myocardial ischemia-reperfusion injury in rats by activating Nrf2 nuclear translocation to regulate the balance of mitochondrial fission and fusion

in Cardiovascular Pharmacology and Drug Discovery

Lili Xu
Jiedong Zhou
Haifei Lou
Haodi Gu
Haixia Xu
Zuoquan Zhong
Hui Lin
Chengjian Jiang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1506388

1,001 views

Original Research

Published on 16 May 2025

Treatment adherence, persistence, and effectiveness of fixed dose combination versus free combination therapy of rosuvastatin–ezetimibe as a lipid-lowering therapy

in Cardiovascular Pharmacology and Drug Discovery

Mihail Samnaliev
Irfan Khan
Praveen Potukuchi
Kelly Lee
Genevieve Garon
Charlie Nicholls

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1461416

1,767 views

Original Research

Published on 12 May 2025

Genetic and clinical determinants of MACE and haemorrhage in antiplatelet therapy: insights from pharmacogenomic analysis

in Cardiovascular Pharmacology and Drug Discovery

Yubo Wang
Shuangli Yuan
Muyun Li
Wenling Feng
Jing Li
Wenwen Chen
Aliye Berdi
Yulian Kou
Yuan Yuan
Jun Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1572389

1,031 views

Original Research

Published on 09 May 2025

Brown adipocyte-derived exosomes in type 2 diabetes mellitus impair endothelial function via regulating intracellular calcium cycle

in Cardiovascular Pharmacology and Drug Discovery

Xiaojie Ruan
Wei Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1546325

1,228 views

Original Research

Published on 06 May 2025

Adverse events associated with amlodipine: a pharmacovigilance study using the FDA adverse event reporting system

in Cardiovascular Pharmacology and Drug Discovery

Jiazhen Jiang
Qian Zhong
Xinyu Zhou
Lisi Zhou
Jiyuan Zheng
Bingshuo Liu
Xingwei Di

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1504671

2,553 views

Original Research

Published on 01 May 2025

Drug-induced cardiac arrest: a pharmacovigilance study from 2004–2024 based on FAERS database

in Cardiovascular Pharmacology and Drug Discovery

Gaocan Ren
Pingping Huang
Jinhui Zhang
Jin Liu
Zian Yan
Xiaochang Ma

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1498700

2,380 views