Frontiers in Cell and Developmental Biology

Original Research

Published on 08 Sep 2025

Integrated metabolomics and network pharmacology to investigate the anti-hyperlipidemia effect of geniposidic acid on high-fat diet induced mice

in Cellular Biochemistry

Ruiting Tang
Kun Li
Mengting Liang
Pengwei Wang
Zeyun Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1655114

2,036 views
1 citation

Review

Published on 08 Sep 2025

m6A: a novel strategy for osteoporosis treatment

in Molecular and Cellular Pathology

Chunlu Yan
Xiaolong Xiao
Fan Yang
Yangyang Shi
Qiao Wan
Yan Zhang
Fangyu An

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603068

2,200 views

Review

Published on 05 Sep 2025

Ferroptosis and bone metabolic diseases: the dual regulatory role of the Nrf2/HO-1 signaling axis

in Cell Death and Survival

Wei Nan
Wen-Ming Zhou
Jian-Lan Zi
Yong-Qiang Shi
Yan-Bo Dong
Wei Song
Yan-Chao Ma
Hai-Hong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1615197

3,925 views
3 citations

Review

Published on 05 Sep 2025

Interplay of replication stress response and immune microenvironment in high-grade serous ovarian cancer

in Cancer Cell Biology

Laura Venegas
Stephanie Lheureux

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1638964

3,085 views
1 citation

Original Research

Published on 04 Sep 2025

Interplay of KIR2DL5, nitric oxide, and tobacco smoking in predisposition to bladder cancer

in Cancer Cell Biology

Inmaculada Ruiz-Lorente
Lourdes Gimeno
Alicia López-Abad
Pedro López Cubillana
Tomás Fernández Aparicio
Lucas Jesús Asensio Egea
Juan Moreno Avilés
Gloria Doñate Iñiguez
Pablo Luis Guzmán Martínez-Valls
Gerardo Server

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1632101

1,571 views

Original Research

Published on 04 Sep 2025

Artificial intelligence applications facilitate decision-making in cataract surgery for highly myopic patients

in Molecular and Cellular Pathology

Kaimeng Su
Wenwen He
Haifeng Jiang
Keke Zhang
Jiao Qi
Jiaqi Meng
Yu Du
Kaiwen Cheng
Xiaoxin Hu
Dongling Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1613634

2,476 views
1 citation

Original Research

Published on 04 Sep 2025

Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells

in Stem Cell Research

Yuanyuan Xie
Junrong Zhang
Rong Du
Jingjing Ji
Jingjing Lu
Haoxuan Li
Yunzhao Xu
Yuquan Zhang
Xi Cheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1650614

1,544 views

Original Research

Published on 04 Sep 2025

ANXA1 and ARG2 drive T cell proliferation in ischemia-reperfusion injury: integrated bulk and single-cell transcriptomic analysis

in Cell Death and Survival

Haofeng Zheng
Kaiming He
Jianchao Wei
Wangtianxu Zhou
Zhiyi Kong
Qingfu Dai
Jieyi Dong
Zihuan Luo
Qiquan Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1673163

2,795 views

Original Research

Published on 04 Sep 2025

Multi-transcriptomics analysis of ferroptosis related genes reveals CAFs exosomal COX4I2 as a novel therapeutic target in osteosarcoma

in Signaling

Xiaoying Niu
Xinxin Zhang
Zhongyi Li
Wen Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1620648

3,452 views

Review

Published on 03 Sep 2025

Organoids in biliary research: insights into developmental signaling and applications in disease modeling

in Signaling

Boming Peng
Min Huang
Jianquan Zhang
Yang Xiang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1656019

3,988 views

Original Research

Published on 03 Sep 2025

Specific inhibition of glutamine synthase involved in the metabolic pathway of amino acids is associated with anti-arthritic effects of sinomenine hydrochloride

in Cellular Biochemistry

Gejing Li
Zhaoli Su
Yuanyuan Tang
Hong Huang
Junlan Zhang
Ye Lin
Qin Zhang
Xiong Cai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1658089

2,141 views
1 citation

Original Research

Published on 03 Sep 2025

SPARC aberrant methylation in idiopathic pulmonary fibrosis: an explorative study

in Cancer Cell Biology

Federico Pio Fabrizio
Angelo Sparaneo
Flavia Centra
Francesco Delli Muti
Paola Parente
Massimiliano Copetti
Marco Donatello Delcuratolo
Antonio Rossi
Elisa Gili
Giulio Rossi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1639844

2,042 views

Original Research

Published on 03 Sep 2025

The mechanosensitive protein ANTXR1 is involved in maintaining cartilage homeostasis in post-traumatic osteoarthritis

in Molecular and Cellular Pathology

Zhuangzhuang Miao
Junjie Liu
Pengfei Cheng
Yinghao Shen
Jiahang Tang
Jiajie Zhu
Weiwei Liu
Xuchang Zhou
Hongying Jing

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1625333

2,470 views

Original Research

Published on 03 Sep 2025

Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verification

in Cell Death and Survival

Yueming Zhang
Fengwei Huang
Jinghui Zhai
Jingmeng Sun
Boyu Li
Sixi Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1629110

1,985 views

Mini Review

Published on 03 Sep 2025

Specialised features of melanosomes in health and disease in the retinal pigment epithelium

in Membrane Traffic and Organelle Dynamics

Dilyana Doncheva
Emily R. Eden
Clare E. Futter

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593840

3,433 views

Review

Published on 03 Sep 2025

CRISPR/Cas-edited iPSCs and mesenchymal stem cells: a concise review of their potential in thalassemia therapy

in Stem Cell Research

Jiaojiao Shu
Xin Xie
Sixi Wang
Zuochen Du
Pei Huang
Yan Chen
Zhixu He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1595897

4,277 views

Review

Published on 03 Sep 2025

Stem/progenitor cell-based therapy for Duchenne muscular dystrophy

in Stem Cell Research

Tsukasa Tominari
Chaitra Sathyaprakash
Yoshitsugu Aoki

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1640275

5,068 views

Review

Published on 03 Sep 2025

Unlocking hematopoietic stem cell potential: integrative computational approaches for genomic and transcriptomic analysis

in Stem Cell Research

Pawan Kumar Raghav
Basudha Banerjee
Rajni Chadha

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1589823

2,681 views

Original Research

Published on 03 Sep 2025

CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration

in Cellular Biochemistry

Kexin Xu
Ning Yang
Lu Yu
Zhiyi Wang
Ningzhi Zhang
Wenye Cao
Yiqiao Xing

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1652041

1,813 views
2 citations

Correction

Published on 03 Sep 2025

Correction: Testicular immunosenescence: a key player in age-related spermatogenic decline

in Cell Death and Survival

Ming-Wei Zhan
Mu-Hua Zhou
Bin-Bin Zhao
Xiao-Jie Bao
Yibo Chen
Jingyu Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1687852

1,321 views

Original Research

Published on 03 Sep 2025

The m6A demethylase FTO suppresses glioma proliferation by regulating the EREG/PI3K/Akt signaling pathway

in Epigenomics and Epigenetics

Yong Zhai
Caili Li
Lihui Cao
Shen Zhang
Xiao Liu
Junwei Ren
Yue Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1667990

2,962 views

Original Research

Published on 02 Sep 2025

Variable expression of hepatic genes in different liver tumor cell lines: conclusions for drug testing

in Cancer Cell Biology

Monika Joanna Wisniewska
Agnieszka Wencel
Malgorzata Jakubowska
Joanna Agata Motyl
Krzysztof Dudek
Beata Burzynska
Dorota Genowefa Pijanowska
Krzysztof Dariusz Pluta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1646602

1,880 views

Review

Published on 02 Sep 2025

The role of Caveolin-1 in tumor-derived extracellular vesicle biology and its implications

in Membrane Traffic and Organelle Dynamics

Satish Kailasam Mani
Christophe Lamaze
Cristian Saquel

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1656953

2,682 views
1 citation

Original Research

Published on 01 Sep 2025

Decoding the prenatal clock of sheep muscle fiber type differentiation: a temporal map from embryonic to mature types

in Embryonic Development

Zhenzhen Gu
Weiwei Duan
Chenxi Liu
Wenrong Li
Ning Zhang
Bin Han
Mingjun Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1649640

2,388 views
1 citation

13,003 articles

articles

Integrated metabolomics and network pharmacology to investigate the anti-hyperlipidemia effect of geniposidic acid on high-fat diet induced mice

m6A: a novel strategy for osteoporosis treatment

Ferroptosis and bone metabolic diseases: the dual regulatory role of the Nrf2/HO-1 signaling axis

Interplay of replication stress response and immune microenvironment in high-grade serous ovarian cancer

Interplay of KIR2DL5, nitric oxide, and tobacco smoking in predisposition to bladder cancer

Artificial intelligence applications facilitate decision-making in cataract surgery for highly myopic patients

Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells

ANXA1 and ARG2 drive T cell proliferation in ischemia-reperfusion injury: integrated bulk and single-cell transcriptomic analysis

Multi-transcriptomics analysis of ferroptosis related genes reveals CAFs exosomal COX4I2 as a novel therapeutic target in osteosarcoma

Organoids in biliary research: insights into developmental signaling and applications in disease modeling

Specific inhibition of glutamine synthase involved in the metabolic pathway of amino acids is associated with anti-arthritic effects of sinomenine hydrochloride

SPARC aberrant methylation in idiopathic pulmonary fibrosis: an explorative study

The mechanosensitive protein ANTXR1 is involved in maintaining cartilage homeostasis in post-traumatic osteoarthritis

Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verification

Specialised features of melanosomes in health and disease in the retinal pigment epithelium

CRISPR/Cas-edited iPSCs and mesenchymal stem cells: a concise review of their potential in thalassemia therapy

Stem/progenitor cell-based therapy for Duchenne muscular dystrophy

Unlocking hematopoietic stem cell potential: integrative computational approaches for genomic and transcriptomic analysis

CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration

Correction: Testicular immunosenescence: a key player in age-related spermatogenic decline

The m6A demethylase FTO suppresses glioma proliferation by regulating the EREG/PI3K/Akt signaling pathway

Variable expression of hepatic genes in different liver tumor cell lines: conclusions for drug testing

The role of Caveolin-1 in tumor-derived extracellular vesicle biology and its implications

Decoding the prenatal clock of sheep muscle fiber type differentiation: a temporal map from embryonic to mature types