Frontiers in Cell and Developmental Biology

Editorial

Published on 01 Sep 2025

Editorial: Sperm epigenetic code: implications in reproductive health and paternal contribution to embryo development

in Molecular and Cellular Reproduction

Marta Lombò
Gilda Cobellis
Francesco Manfrevola

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1666435

1,855 views

Original Research

Published on 01 Sep 2025

GMP-compliant, serum-free cultures preserve therapeutic potential of extracellular vesicles from human mesenchymal stromal cells

in Stem Cell Research

Filippo Calascibetta
Annalisa Martorana
Margot Lo Pinto
Claudia Carcione
Salvatore D’Arpa
Giandomenico Amico
Vitale Miceli
Nicola Cuscino
Gioacchin Iannolo
Lorenzo Volpe

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633912

2,509 views
1 citation

Original Research

Published on 01 Sep 2025

Integrated transcriptomic analysis identifies lactylation-linked gemcitabine resistance and therapeutic targets in intrahepatic cholangiocarcinoma

in Cancer Cell Biology

Wenwei Xie
Jialiang Hu
Hanmei Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1611434

3,022 views

Original Research

Published on 01 Sep 2025

Identification of the key immune gene NR3C1 as a diagnostic biomarker in differentiating ovarian borderline tumors from benign tumors

in Molecular and Cellular Pathology

Shiying Chen
Yumin Ke
Yajing Xie
Zhimei Zhou
Weihong Chen
Li Huang
Liying Sheng
Yueli Wang
Shunlan Liu
Zhuna Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1602192

2,013 views

Review

Published on 01 Sep 2025

Examination of degenerative and damaged glenohumeral joint tissue samples with calorimetric analyses

in Molecular and Cellular Pathology

Dénes Lőrinczy
András Bata
László Bogdán
Árpád Pillér
Laszlo G. Nöt

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1653732

1,343 views

Original Research

Published on 29 Aug 2025

A human Angelman Syndrome class II pluripotent stem cell line with fluorescent paternal UBE3A reporter

in Stem Cell Research

Gautami R. Kelkar
Samantha R. Stuppy
Dilara Sen
Z. Begum Yagci
Linna Han
Lexi Land
Jessica K. Hartman
Albert J. Keung

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1665693

2,627 views

Original Research

Published on 29 Aug 2025

The emergence of chordin-like1 in gnathostomes may have contributed to the evolution of paired appendages

in Evolutionary Developmental Biology

Galina V. Ermakova
Irina V. Meyntser
Nikolai S. Mugue
Vassily A. Lyubetsky
Andrey G. Zaraisky
Andrey V. Bayramov

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1649996

2,763 views
1 citation

Original Research

Published on 29 Aug 2025

Comprehensive analysis of the papillary thyroid carcinoma identifies CSGALNACT1 as a proliferation driver and prognostic biomarker

in Cancer Cell Biology

Yu Zhao
Juan Zhang
Yong Yao
Linna Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1638348

1,964 views

Original Research

Published on 29 Aug 2025

Integrating microarray data and single-cell RNA-seq reveals correlation between kit and nmyc in mouse spermatogonia stem cell population

in Molecular and Cellular Reproduction

Danial Hashemi Karoii
Hossein Azizi
Thomas Skutella

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634347

3,548 views
3 citations

Original Research

Published on 29 Aug 2025

Fibroblast growth factor 19 regulates polycystic ovary syndrome progression via FGFR4-ERK-NRF2 pathway

in Molecular and Cellular Pathology

Junjie Qu
Meiting Qiu
Jingyun Wang
Zhiqin Chen
Miaoxin Chen
Xiaoming Teng
Yiran Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626938

2,439 views
1 citation

Review

Published on 29 Aug 2025

Exploring the protective effects of coenzyme Q10 on female fertility

in Molecular and Cellular Reproduction

Yu Jiang
Yao Han
Pengyun Qiao
Fa Ren

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633166

16,065 views

Original Research

Published on 29 Aug 2025

Investigating the metabolic reprogramming mechanisms in diabetic nephropathy: a comprehensive analysis using bioinformatics and machine learning

in Cancer Cell Biology

Shan He
Yi Wei Chen
Jian Ye
Yu Wang
Qin Kai Chen
Si Yi Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630708

2,981 views

Original Research

Published on 29 Aug 2025

Maternal and fetal outcomes in 151 cases of thrombocytopenia in pregnancy

in Molecular and Cellular Pathology

Chinwe Oluchi-Amaka Ibeh
Feng Guo
Xiuhua Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608647

2,569 views

Original Research

Published on 29 Aug 2025

Syndecan-4 interacts directly with β-parvin and regulates the ILK-PINCH-β-parvin complex, the β-parvin-β-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent manner

in Membrane Traffic and Organelle Dynamics

Sabrina Bech Mathiesen
Thea Parsberg Støle
Andreas Romaine
Marianne Lunde
Marita Martinsen
Jan Magnus Aronsen
Ivar Sjaastad
William E. Louch
Geir Christensen
Cathrine Rein Carlson

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1569185

2,284 views
2 citations

Original Research

Published on 29 Aug 2025

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans

in Molecular and Cellular Reproduction

Chao-Wen Wang
Phebe Chiu
Sophia Monsalve
Ricardo Roure
Xiaofei Bai
Jia-Jin Law
Yu-Ching Wu
Yet-Ran Chen
You-Liang Cheng
Rey-Huei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622695

3,220 views

Review

Published on 29 Aug 2025

The fibularis tertius muscle revisited: comparative anatomy, developmental classification, and evolutionary-clinical implications

in Evolutionary Developmental Biology

Łukasz Olewnik
Ingrid C. Landfald
Daria Domosławka
George Triantafyllou
Georgi P. Georgiev
Maria Piagkou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1647572

2,858 views

Original Research

Published on 29 Aug 2025

Smarce1 fine-tunes cardiomyocyte proliferation in the embryonic zebrafish heart

in Embryonic Development

Deung-Dae Park
Tillman Dahme
Leonie Krieg
Steffen Just
Wolfgang Rottbauer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636944

2,324 views

Mini Review

Published on 29 Aug 2025

Unwinding new therapeutic opportunities in rhabdomyosarcoma: the role of RNA helicase DDX5

in Cancer Cell Biology

Valeria Bianconi
Chiara Mozzetta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1662619

2,408 views

Original Research

Published on 29 Aug 2025

SIRT1 retention in elongating spermatids interferes with histone displacement by counteracting MOF-dependent H4K16 acetylation

in Molecular and Cellular Reproduction

Veronica Porreca
Teresa Chioccarelli
Francesco Albano
Valeria Nittoli
Giulia Ricci
Concetta Ambrosino
Rosanna Chianese
Vincenza Grazia Mele
Antonella Migliaccio
Mariano Stornaiuolo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1524919

2,059 views
1 citation

Review

Published on 29 Aug 2025

The future of embryo engineering and fertility research in interdisciplinary collaboration

in Embryonic Development

Julia Soczyńska
Wiktor Gawełczyk
Julia Papierkowska
Adrian Muzyka
Krzysztof Majcherczyk
Patrycja Obrycka
Mateusz Żołyniak
Sławomir Woźniak

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619050

6,751 views

Correction

Published on 28 Aug 2025

Correction: PARP1 inhibitor combined with oxaliplatin efficiently suppresses oxaliplatin resistance in gastric cancer-derived organoids via homologous recombination and the base excision repair pathway

in Cancer Cell Biology

Huafu Li
Chunming Wang
Linxiang Lan
Wenhui Wu
Ian Evans
E. Josue Ruiz
Leping Yan
Zhijun Zhou
Joaquim M. Oliveira
Rui L. Reis

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1672461

1,610 views

Review

Published on 28 Aug 2025

Reprogramming cancer immunity with next-generation combination therapies

in Cancer Cell Biology

Nikolaos C. Kyriakidis
Carolina E. Echeverría
Jhommara Bautista
Sebastián Rivera-Orellana
María José Ramos-Medina
Camila Salazar-Santoliva
Juan S. Izquierdo-Condoy
Esteban Ortiz-Prado
Santiago Guerrero
Andrés López-Cortés

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1652047

6,299 views
13 citations

Original Research

Published on 26 Aug 2025

Slit2 inhibits SRC-PI3K signaling pathway, regulates osteoclast differentiation of macrophages and reduces bone resorption

in Signaling

Qing Ge
Yaokun Zou
Huizhi Deng
Zhe Yang
Linhu Ge
Jieying Huang
Jianqiang Cai
Liping Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1632882

2,460 views

Review

Published on 26 Aug 2025

Medical embryology and regenerative medicine: research and applications in clinical practice

in Embryonic Development

Julia Soczyńska
Wiktor Gawełczyk
Patrycja Obrycka
Mateusz Żołyniak
Adrian Muzyka
Krzysztof Majcherczyk
Julia Papierkowska
Sławomir Woźniak

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619036

4,879 views
1 citation

13,003 articles

articles

Editorial: Sperm epigenetic code: implications in reproductive health and paternal contribution to embryo development

GMP-compliant, serum-free cultures preserve therapeutic potential of extracellular vesicles from human mesenchymal stromal cells

Integrated transcriptomic analysis identifies lactylation-linked gemcitabine resistance and therapeutic targets in intrahepatic cholangiocarcinoma

Identification of the key immune gene NR3C1 as a diagnostic biomarker in differentiating ovarian borderline tumors from benign tumors

Examination of degenerative and damaged glenohumeral joint tissue samples with calorimetric analyses

A human Angelman Syndrome class II pluripotent stem cell line with fluorescent paternal UBE3A reporter

The emergence of chordin-like1 in gnathostomes may have contributed to the evolution of paired appendages

Comprehensive analysis of the papillary thyroid carcinoma identifies CSGALNACT1 as a proliferation driver and prognostic biomarker

Integrating microarray data and single-cell RNA-seq reveals correlation between kit and nmyc in mouse spermatogonia stem cell population

Fibroblast growth factor 19 regulates polycystic ovary syndrome progression via FGFR4-ERK-NRF2 pathway

Exploring the protective effects of coenzyme Q10 on female fertility

Investigating the metabolic reprogramming mechanisms in diabetic nephropathy: a comprehensive analysis using bioinformatics and machine learning

Maternal and fetal outcomes in 151 cases of thrombocytopenia in pregnancy

Syndecan-4 interacts directly with β-parvin and regulates the ILK-PINCH-β-parvin complex, the β-parvin-β-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent manner

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans

The fibularis tertius muscle revisited: comparative anatomy, developmental classification, and evolutionary-clinical implications

Smarce1 fine-tunes cardiomyocyte proliferation in the embryonic zebrafish heart

Unwinding new therapeutic opportunities in rhabdomyosarcoma: the role of RNA helicase DDX5

SIRT1 retention in elongating spermatids interferes with histone displacement by counteracting MOF-dependent H4K16 acetylation

The future of embryo engineering and fertility research in interdisciplinary collaboration

Correction: PARP1 inhibitor combined with oxaliplatin efficiently suppresses oxaliplatin resistance in gastric cancer-derived organoids via homologous recombination and the base excision repair pathway

Reprogramming cancer immunity with next-generation combination therapies

Slit2 inhibits SRC-PI3K signaling pathway, regulates osteoclast differentiation of macrophages and reduces bone resorption

Medical embryology and regenerative medicine: research and applications in clinical practice