Frontiers in Cell and Developmental Biology

Original Research

Published on 10 Jul 2025

Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway

in Stem Cell Research

Xuan Zhou
Shaoliang Xing
Lina Zhang
Jungu Lu
Deming Li
Yating Wang
Yuhang Ma
Weiqin Chang
Manman Su

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1631973

2,350 views
2 citations

Review

Published on 10 Jul 2025

Mechanosensitive Piezo channels in mineralized tissues: emerging roles in osteodental adaptation and disease

in Signaling

Junchi Dong
Ran Li
Yuhuang Chen
Guixin Zhu
Xing Liang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607337

4,826 views

Review

Published on 09 Jul 2025

Schwann cell reprogramming via EMT-like program following peripheral nerve injury and during nerve regeneration

in Cell Adhesion and Migration

Wenyu Dai
Yang Miao
Sheng Yi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1621380

3,834 views
2 citations

Original Research

Published on 09 Jul 2025

Mitochondrial insights: key biomarkers and potential treatments for diabetic nephropathy and sarcopenia

in Cancer Cell Biology

Yi Wei Chen
Shan He
Yu Wang
Lian Ying Hu
Qin Kai Chen
Si Yi Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1596204

3,475 views
1 citation

Original Research

Published on 09 Jul 2025

Using deep learning to screen OCTA images for hypertension to reduce the risk of serious complications

in Molecular and Cellular Pathology

Yiheng Ding
Ziqiang Wei
Chaoyun Wang
Xinyue Li
Bingbing Li
Xueting Liu
Zhijie Fu
Hongwei Mo
Hong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1581785

1,686 views

Review

Published on 09 Jul 2025

Harnessing the interaction between redox signaling and senescence to restrain tumor drug resistance

in Cancer Cell Biology

Hao Wu
Yang Yu
Xiangning He
Yanju Gong
Jianqing Huang
Peijie Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1639772

3,659 views
4 citations

Editorial

Published on 09 Jul 2025

Editorial: Functions and regulation of p90RSK and its family: mechanisms, roles in diseases, and implications in therapeutics

in Signaling

Ling Lin
Nhat-Tu Le
Kebin Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1648101

1,118 views

Original Research

Published on 09 Jul 2025

Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma

in Cancer Cell Biology

Mingguang Zhang
Shuohui Dong
Wei Rao
Shiwen Mei
Gang Hu
Ling Liu
Zhen Wang
Jianqiang Tang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630231

3,294 views
2 citations

Original Research

Published on 09 Jul 2025

Itpka depletion implicates defects in anterior neural development of Xenopus laevis

in Embryonic Development

Ernestine Saumweber
Marie-Christine Becker
Sophie Kunkel
Jana Welke
Sandra Schott
Christian Vizinho-Vieira
Selina Faoual
Michael J. Schmeisser
Susanne J. Kühl

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610183

2,285 views

Original Research

Published on 09 Jul 2025

Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcinoma

in Cancer Cell Biology

Yun Zhao
Jing Yang
Yamei Jiang
Jingbiao Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1629683

3,186 views
5 citations

Review

Published on 09 Jul 2025

The pathogenesis and therapeutic strategies of heat stroke-induced endothelial injury

in Signaling

Shaokang Wang
Xiaoting Zhang
Yongqi Zhang
Nannan Wu
Lulong Bo
Meitang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1569346

4,644 views
3 citations

Review

Published on 08 Jul 2025

Epidermal lamellar bodies, essential organelles for the skin barrier

in Membrane Traffic and Organelle Dynamics

Corinne Leprince
Michel Simon

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1597884

6,457 views
1 citation

Review

Published on 08 Jul 2025

The role of lipophagy in liver cancer: mechanisms and targeted therapeutic interventions

in Cancer Cell Biology

Peiyu Han
Han Wang
Yuyu Chen
Yuqiu Ge
Huiting Xu
Hongbo Ren
Yiteng Meng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1562542

3,236 views
3 citations

Editorial

Published on 07 Jul 2025

Editorial: Advancements in hematopoietic stem cell proliferation and self-renewal maintenance

in Stem Cell Research

Pawan Kumar Raghav
Gurudutta Gangenahalli
Takahiko Hara

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607145

2,646 views

Original Research

Published on 07 Jul 2025

Wnt-dependent mechanism of the apical constriction of roof plate cells in developing mouse spinal cord

in Morphogenesis and Patterning

Takuma Shinozuka
Tadashi Okubo
Noriaki Sasai
Shinji Takada

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1571770

2,445 views
1 citation

Review

Published on 07 Jul 2025

The vascular endothelium as decision maker in lung injury

in Molecular and Cellular Pathology

Diana Klein

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564627

3,151 views
2 citations

Original Research

Published on 07 Jul 2025

Evaluating multiple large language models on orbital diseases

in Molecular and Cellular Pathology

Qi-Chen Yang
Yan-Mei Zeng
Hong Wei
Cheng Chen
Qian Ling
Xiao-Yu Wang
Xu Chen
Yi Shao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1574378

2,199 views

Original Research

Published on 07 Jul 2025

Water temperature modulates multidimensional plastic responses to water flow during the ontogeny of a neotropical fish (Astyanax lacustris, characiformes)

in Evolutionary Developmental Biology

Leandro Lofeu
Bianca Bonini-Campos
Tiana Kohlsdorf

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1531162

2,533 views

Original Research

Published on 04 Jul 2025

Integration of chromosome conformation and gene expression networks reveals regulatory mechanisms in triple negative breast cancer

in Epigenomics and Epigenetics

Helena Reyes-Gopar
Keila Adonai Pérez-Fuentes
Matthew L. Bendall
Enrique Hernández-Lemus

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1597245

2,439 views

Original Research

Published on 04 Jul 2025

VE-PTP controls a fluid shear stress set point that governs cell morphological responses through Tie-2

in Cell Adhesion and Migration

Keisuke Shirakura
Mana Ghanbarpour Houshangi
Kevin G. Peters
Dietmar Vestweber

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603517

2,636 views

Review

Published on 04 Jul 2025

Involvement of role of HMGB1-NLRP3 pathway in systemic disorders

in Signaling

Lei Yang
Xue Li
Xiaoming Zhu
Futao Ge
Yuantao Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600596

3,218 views
2 citations

Original Research

Published on 03 Jul 2025

Age-dependent integration of cortical progenitors transplanted at CSF-neurogenic niche interface

in Stem Cell Research

Gretchen Greene
Nikorn Pothayee
Jahandar Jahanipour
Hyesoo Jie
Jung-Hwa Tao-Cheng
Emily Petrus
Dragan Maric
Alan P. Koretsky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577045

2,479 views
1 citation

Original Research

Published on 03 Jul 2025

PD-L1 expression predicts the efficacy of PD-1 blockade plus chemotherapy versus chemotherapy alone in treatment-naïve advanced or metastatic gastric cancer: a pooled analysis of reconstructed individual patient-level data from two randomized trials

in Cancer Cell Biology

Wei Zhou
Zeng-Zhi Cai
Zhuolin Fan
Xu Zheng
Yu-Tong Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636288

3,219 views
1 citation

Original Research

Published on 03 Jul 2025

Temporal dynamics of gene and protein signatures following volumetric muscle loss

in Molecular and Cellular Pathology

Ishita Jain
Beu P. Oropeza
Caroline Hu
Gladys Chiang
Sree Aravindan
Renato Reyes
Daniel Yuhang Li
Paul Cheng
Ngan F. Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606609

2,401 views
2 citations

13,012 articles

articles

Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway

Mechanosensitive Piezo channels in mineralized tissues: emerging roles in osteodental adaptation and disease

Schwann cell reprogramming via EMT-like program following peripheral nerve injury and during nerve regeneration

Mitochondrial insights: key biomarkers and potential treatments for diabetic nephropathy and sarcopenia

Using deep learning to screen OCTA images for hypertension to reduce the risk of serious complications

Harnessing the interaction between redox signaling and senescence to restrain tumor drug resistance

Editorial: Functions and regulation of p90RSK and its family: mechanisms, roles in diseases, and implications in therapeutics

Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma

Itpka depletion implicates defects in anterior neural development of Xenopus laevis

Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcinoma

The pathogenesis and therapeutic strategies of heat stroke-induced endothelial injury

Epidermal lamellar bodies, essential organelles for the skin barrier

The role of lipophagy in liver cancer: mechanisms and targeted therapeutic interventions

Editorial: Advancements in hematopoietic stem cell proliferation and self-renewal maintenance

Wnt-dependent mechanism of the apical constriction of roof plate cells in developing mouse spinal cord

The vascular endothelium as decision maker in lung injury

Evaluating multiple large language models on orbital diseases

Water temperature modulates multidimensional plastic responses to water flow during the ontogeny of a neotropical fish (Astyanax lacustris, characiformes)

Integration of chromosome conformation and gene expression networks reveals regulatory mechanisms in triple negative breast cancer

VE-PTP controls a fluid shear stress set point that governs cell morphological responses through Tie-2

Involvement of role of HMGB1-NLRP3 pathway in systemic disorders

Age-dependent integration of cortical progenitors transplanted at CSF-neurogenic niche interface

PD-L1 expression predicts the efficacy of PD-1 blockade plus chemotherapy versus chemotherapy alone in treatment-naïve advanced or metastatic gastric cancer: a pooled analysis of reconstructed individual patient-level data from two randomized trials

Temporal dynamics of gene and protein signatures following volumetric muscle loss