Frontiers in Cell and Developmental Biology

Original Research

Published on 09 Jun 2025

ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer

in Cancer Cell Biology

Jinpeng Cen
Jiading Guo
Xianzi Zeng
Xianlu Song
Shengdong Ge
Mingkun Chen
Qianyi Li
Yuzhong Yu
Daojun Lv
Shanchao Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1598400

3,559 views
1 citation

Perspective

Published on 09 Jun 2025

Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors

in Stem Cell Research

Wendy V. Jaraba-Álvarez
Ashanti C. Uscanga-Palomeque
Vanesa Sanchez-Giraldo
Claudia Madrid
Hector Ortega-Arellano
Karolynn Halpert
Carolina Quintero-Gil

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609082

5,408 views
8 citations

Mini Review

Published on 09 Jun 2025

Cilia and transcription: a mini review

in Cell Growth and Division

Jason M. Brown

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582796

3,148 views
1 citation

Original Research

Published on 06 Jun 2025

MSLI-Net: retinal disease detection network based on multi-segment localization and multi-scale interaction

in Molecular and Cellular Pathology

Zhenjia Qi
Jin Hong
Jilan Cheng
Guoli Long
Hanyu Wang
Siyue Li
Shuangliang Cao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608325

3,293 views
3 citations

Original Research

Published on 06 Jun 2025

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway

in Molecular and Cellular Pathology

Tao Liu
Zhaohui Li
Wei Zhang
Xuzhao Guo
Guobin Liu
Dalong Yang
Sidong Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564458

2,655 views

Brief Research Report

Published on 06 Jun 2025

Hedgehog signaling controls astral microtubules and mitotic spindle orientation in neural progenitors and iPSCs

in Embryonic Development

Fengming Liu
Anna Medyukhina
Kris M. Olesen
Abbas Shirinifard
Hongjian Jin
Lei Li
Marina Mapelli
Khaled Khairy
Young-Goo Han

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582924

2,524 views
1 citation

Brief Research Report

Published on 05 Jun 2025

Molecular analysis of RAX2-regulated retinal development using human retinal organoids at a single-cell resolution

in Stem Cell Research

Shaojun Wang
Yi Sun
Jie Na
Yue Huang
Guang Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609826

2,938 views

Original Research

Published on 05 Jun 2025

Proteasome caspase-like activity regulates stress granules and proteasome condensates

in Signaling

Shirel Steinberger
Julia Adler
Nadav Myers
Yosef Shaul

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1570499

2,882 views

Perspective

Published on 05 Jun 2025

Lowe Syndrome and Me: a co-creation video series connecting patients, caregivers, and researchers

in Membrane Traffic and Organelle Dynamics

Theresa Haugen
Jennifer L. Gallop
Hélène Doerflinger

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610207

1,779 views

Review

Published on 05 Jun 2025

p90RSK modulates inter-and intracellular signaling in kidney diseases

in Signaling

Ling Lin
Kebin Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593914

1,804 views

Review

Published on 05 Jun 2025

Immune dysregulation in ulcerative colitis: pathogenic mechanisms and therapeutic strategies of traditional Chinese medicine

in Molecular and Cellular Pathology

Xudong Tang
Yilin Huang
Ying Zhu
Yin Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610435

8,885 views
12 citations

Editorial

Published on 05 Jun 2025

Editorial: Rehabilitation and regeneration in orthopaedic: from cellular regulation to innovative medical technologies

in Cell Growth and Division

Weidan Wang
Ye Li
Jiannan Li
Weihao Yuan
Dewei Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633691

1,443 views

Original Research

Published on 04 Jun 2025

Platinum(IV) anticancer therapies and cathepsin B: innovative strategies for overcoming resistance in glioblastoma cells

in Cancer Cell Biology

Claudio Casali
Ludovica Gaiaschi
Enrico Pelloni
Federica Gola
Margherita Cavallo
Gloria Milanesi
Mauro Ravera
Marco Biggiogera
Fabrizio De Luca
Maria Grazia Bottone

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1506206

2,830 views

Review

Published on 04 Jun 2025

Coming of age: could obesity-related metabolic complications be treated by targeting senescent cells?

in Cell Growth and Division

Barbora Judita Kasperova
Anna Cinkajzlova
Ludek Horvath
Petr Svoboda
Martin Haluzik
Sona Stemberkova Hubackova

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622107

3,359 views
1 citation

Review

Published on 04 Jun 2025

Role of circadian clock in female embryo implantation

in Embryonic Development

Yukai Zhou
Xiaodie He
Zhenxin Chen
Yucong Gou
Kaixin Zhou
Jinrong Huang
Mei Chen
Jin Hong
Lei Gao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607491

4,287 views

Original Research

Published on 04 Jun 2025

Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts

in Stem Cell Research

Paulina Kasprzycka
Maria Anna Ciemerych
Malgorzata Zimowska

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1592512

2,019 views
1 citation

Original Research

Published on 04 Jun 2025

Identifying a prognostic signature for clear cell renal cell carcinoma: the convergence of single-cell and bulk sequencing with machine learning

in Cancer Cell Biology

Yude Hong
Xiao Hu
Libo Chen
Mingyong Li
Mingxiao Zhang
Weiming Deng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1560095

3,422 views
1 citation

Original Research

Published on 04 Jun 2025

Assessment of synthetic post-therapeutic OCT images using the generative adversarial network in patients with macular edema secondary to retinal vein occlusion

in Molecular and Cellular Pathology

Shi Feng
Jingyuan Yang
Xinyu Zhao
Jianchun Zhao
Yunfeng Du
Weihong Yu
Dayong Ding
Xirong Li
Youxin Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609567

2,202 views
1 citation

Mini Review

Published on 04 Jun 2025

SLC7A11-mediated cell death mechanism in cancer: a comparative study of disulfidptosis and ferroptosis

in Cell Death and Survival

Wen-Wen Zhu
Ying Liu
Ze Yu
Hong-Qiang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1559423

6,337 views
11 citations

Original Research

Published on 04 Jun 2025

Mechanistic insights curcumin’s anti-inflammatory in pancreatic cancer: experimental and computational evidence implicating IL1B interference via IL10RA upregulation and NLRP3/TLR3 downregulation

in Cancer Cell Biology

Jun-Feng Cao
Kuan Hang
Hao Zhang
Qingjie Xia
Xiao Zhang
Jie Men
Jin Tian
Zengliang Xia
Dunshui Liao
Kezhou Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1601908

3,443 views
7 citations

Original Research

Published on 03 Jun 2025

Establishment of human periodontal ligament cell lines with ALPL mutations to mimic dental aspects of hypophosphatasia

in Cellular Biochemistry

Jana Schiffmaier
Sofia Rehling
Katharina Marnet
Angela Borst
Drenka Trivanović
Denitsa Docheva
Franz Jakob
Stephanie Graser
Marietta Herrmann
Daniel Liedtke

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1572571

2,854 views

Original Research

Published on 03 Jun 2025

Degenerated nerve grafts provide similar quality and outcome in reconstructing critical nerve defects as compared to fresh nerve grafts

in Cell Growth and Division

Philipp Tratnig-Frankl
Martin Schmoll
Udo Maierhofer
Johanna Klepetko
Florian J. Jaklin
Lisa H. Jöns
Homayon Zirak
Christopher Festin
Leopold Harnoncourt
Vlad Tereshenko

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1568935

2,176 views

Original Research

Published on 03 Jun 2025

Intercellular communication between extracellular vesicles from conditioned macrophages and breast cancer cells drives endocrine therapy resistance

in Cancer Cell Biology

María C. Rodriguez-Baili
Miguel Palma-Cobo
César G. Prucca
María Yáñez-Mó
German A. Gil

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1548724

4,344 views
2 citations

Review

Published on 03 Jun 2025

Chronotherapy and intervertebral disc degeneration: understanding the role of circadian rhythm in degenerative processes

in Molecular and Cellular Pathology

Cong Zhang
Rende Zhang
Guanghai Zhao
Zuolong Wu
Wei Song
Rui Ran
Kaisheng Zhou
Haihong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1586193

4,459 views
2 citations

13,016 articles

articles

ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer

Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors

Cilia and transcription: a mini review

MSLI-Net: retinal disease detection network based on multi-segment localization and multi-scale interaction

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway

Hedgehog signaling controls astral microtubules and mitotic spindle orientation in neural progenitors and iPSCs

Molecular analysis of RAX2-regulated retinal development using human retinal organoids at a single-cell resolution

Proteasome caspase-like activity regulates stress granules and proteasome condensates

Lowe Syndrome and Me: a co-creation video series connecting patients, caregivers, and researchers

p90RSK modulates inter-and intracellular signaling in kidney diseases

Immune dysregulation in ulcerative colitis: pathogenic mechanisms and therapeutic strategies of traditional Chinese medicine

Editorial: Rehabilitation and regeneration in orthopaedic: from cellular regulation to innovative medical technologies

Platinum(IV) anticancer therapies and cathepsin B: innovative strategies for overcoming resistance in glioblastoma cells

Coming of age: could obesity-related metabolic complications be treated by targeting senescent cells?

Role of circadian clock in female embryo implantation

Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts

Identifying a prognostic signature for clear cell renal cell carcinoma: the convergence of single-cell and bulk sequencing with machine learning

Assessment of synthetic post-therapeutic OCT images using the generative adversarial network in patients with macular edema secondary to retinal vein occlusion

SLC7A11-mediated cell death mechanism in cancer: a comparative study of disulfidptosis and ferroptosis

Mechanistic insights curcumin’s anti-inflammatory in pancreatic cancer: experimental and computational evidence implicating IL1B interference via IL10RA upregulation and NLRP3/TLR3 downregulation

Establishment of human periodontal ligament cell lines with ALPL mutations to mimic dental aspects of hypophosphatasia

Degenerated nerve grafts provide similar quality and outcome in reconstructing critical nerve defects as compared to fresh nerve grafts

Intercellular communication between extracellular vesicles from conditioned macrophages and breast cancer cells drives endocrine therapy resistance

Chronotherapy and intervertebral disc degeneration: understanding the role of circadian rhythm in degenerative processes