Frontiers in Cell and Developmental Biology

Original Research

Published on 04 Apr 2025

Identification of hub genes associated with decreased fertility in male mice of advanced paternal age

in Evolutionary Developmental Biology

Yang Gao
Ting Zhang
Yan Wang
Haitao Lv
Xiangming Yan
Longlong Fu
Ying Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1520387

2,461 views

Editorial

Published on 04 Apr 2025

Editorial: Methods to develop and study animal cell degeneration disorders resembling human pathologies

in Molecular and Cellular Pathology

Frank Edlich
Marlon R. Schneider

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1575010

1,125 views

Original Research

Published on 04 Apr 2025

GSDME knockout alleviates hematopoietic stem cell irradiation injury and aggravates myeloid-biased differentiation

in Stem Cell Research

Lulu Su
Yinping Dong
Bowen Guan
Yuquan Wang
Yanhua Lu
Xinyue Wang
Wenxuan Li
Qidong Huo
Aimin Meng
Deguan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1544320

2,681 views

Editorial

Published on 03 Apr 2025

Editorial: New strategies for treating fusion-driven sarcomas

in Cancer Cell Biology

Madelyn Espinosa-Cotton
Sean B. Lee
Anand G. Patel

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600133

1,747 views

Original Research

Published on 03 Apr 2025

Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells

in Membrane Traffic and Organelle Dynamics

Ivor Joseph
Jiangmeng Han
Jared Bianchi-Smak
Jiaxing Yang
Jagannatham Naidu Bhupana
Juan Flores
Jack Delucia
Tracy S. Tran
James R. Goldenring
Edward M. Bonder

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1498902

3,265 views
1 citation

Original Research

Published on 03 Apr 2025

TAp73 modulates proliferation and ferroptosis in mammary epithelial cells

in Cell Death and Survival

Wenqiang Sun
Hanjun Ren
Le Chen
Bingfei Zhang
Liping Mei
Jiaqi Wen
Yilu Zhang
Jiaqi Li
Yongping Yan
Songjia Lai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1532910

2,175 views

Original Research

Published on 02 Apr 2025

Heat shock affects the Ca2+/calmodulin-dependent protein kinase II dynamic during bovine sperm capacitation and acrosome reaction

in Molecular and Cellular Reproduction

Thais de Sousa Santos
Isabelle Scarpini Contrim
Daniela Franco da Silva
Mayra Elena Ortiz D’Avila Assumpção
Fabiola Freitas de Paula-Lopes
Weber Beringui Feitosa

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1552282

2,114 views

Original Research

Published on 02 Apr 2025

lncRNA Ubr5 promotes BMSCs apoptosis and inhibits their proliferation and osteogenic differentiation in weightless bone loss

in Molecular and Cellular Pathology

Dong Wang
Yuan Gao
Yingjun Tan
Na Li
Xi Li
Jiaxiang Li
Yikai Pan
Xingcheng Zhao
Ming Yan
Yongchun Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1543929

2,292 views
1 citation

Review

Published on 02 Apr 2025

SIRT3/6/7: promising therapeutic targets for pulmonary fibrosis

in Molecular and Cellular Pathology

Pingping Huang
Dan Qin
Yanling Qin
Sha Tao
Guangnan Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1557384

5,570 views
3 citations

Brief Research Report

Published on 01 Apr 2025

Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities

in Signaling

De Yu Mao
Jordan J. Jesse
Daniel D. Shaye
Jan Kitajewski

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1565262

2,939 views
1 citation

Review

Published on 01 Apr 2025

Targeting tumor angiogenesis and metabolism with photodynamic nanomedicine

in Cancer Cell Biology

Yong Lv
Lihui Pu
Bei Ran
Bo Xiang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1558393

2,596 views
2 citations

Original Research

Published on 31 Mar 2025

Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-β pathway in lung adenocarcinoma

in Cancer Cell Biology

Honghong Dong
Yahui Tian
Shaowei Xin
Yujie Guo
Suxin Jiang
Zitong Wan
Huaiyu Wang
Yong Han

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1557761

3,063 views
1 citation

Review

Published on 31 Mar 2025

Application of human cardiac organoids in cardiovascular disease research

in Stem Cell Research

Hongyan Zhang
Peng Qu
Jun Liu
Panke Cheng
Qian Lei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564889

6,598 views
3 citations

Review

Published on 31 Mar 2025

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosis

in Cell Death and Survival

Suqi Liu
Qian Xi
Xuannian Li
Huaman Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1535601

7,153 views
6 citations

Original Research

Published on 31 Mar 2025

Doxycycline inhibits MMP-2 retinal activity and modulates the angiogenic process in vitro and in vivo

in Molecular and Cellular Pathology

María Lina Formica
María Constanza Paz
María Victoria Vaglienti
Paula Virginia Subirada
Yamila Fernández
Mariana Belén Joray
José Domingo Luna
Pablo Federico Barcelona
Santiago Daniel Palma
María Cecilia Sánchez

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1561250

2,721 views
4 citations

Original Research

Published on 28 Mar 2025

Changes in the metabolome, lipidomein, and gut microbiota in Behçet’s disease

in Molecular and Cellular Pathology

Chen Shang
Sujuan Ji
Wenting Hao
Xiangyu Wei
Jiani Yu
Jiayi Liu
Baoguo Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1530996

2,748 views

Mini Review

Published on 28 Mar 2025

Arx revisited: involved in the development of GABAergic interneurons

in Signaling

Akio Tsuboi
Seiich Yoshihara

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1563515

2,832 views
1 citation

Opinion

Published on 28 Mar 2025

Neuroimmunomodulation in chronic wounds: an opinion

in Molecular and Cellular Pathology

Patrizia Nardini
Stefano Bacci

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1562346

2,135 views
3 citations

Review

Published on 28 Mar 2025

Unveiling the impact of ERAP1 and ERAP2 on migration, angiogenesis and ER stress response

in Cellular Biochemistry

Irma Saulle
Alessandra Velia Vitalyos
Daniel D’Agate
Mario Clerici
Mara Biasin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564649

3,012 views

Original Research

Published on 28 Mar 2025

Increased amounts of cell-free DNA released from a culture with a high content of cancer stem cells

in Cancer Cell Biology

Ileana J. Fernández-Domínguez
Enrique Pérez-Cárdenas
Lucia Taja-Chayeb
Talia Wegman-Ostrosky
Claudia H. S. Caro-Sánchez
Alejandro Zentella-Dehesa
Alfonso Dueñas-González
Horacio López-Basabe
Rocío Morales-Bárcenas
Catalina Trejo-Becerril

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1499936

3,986 views

Review

Published on 28 Mar 2025

Lactylation in CNS disorders: mechanisms, cellular function, and disease relevance

in Cellular Biochemistry

Jiaxin Tian
Tongyu Zhang
Ruidan Zhang
Sijia Hao
Jingyu Dong
Yiyan Chen
Jinpeng Zhou
Yang Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566921

6,534 views
3 citations

Original Research

Published on 27 Mar 2025

KIF2C is essential for meiosis and manchette dynamics in male mice

in Molecular and Cellular Reproduction

Ryua Harima
Mayu Kishinami
Kenshiro Hara
Kentaro Tanemura

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1523593

3,352 views
1 citation

Review

Published on 27 Mar 2025

Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms

in Cell Death and Survival

Namrita Kaur
Sven R. Carlsson
Alf Håkon Lystad

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1559125

8,529 views
8 citations

Original Research

Published on 27 Mar 2025

Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury

in Signaling

Marina García-Bejarano
Riccardo Aucello
Federica Zen
Marwa El Soury
Francesca Cordero
Jesús M. de la Fuente
Isabelle Perroteau
Giulia Ronchi
Giovanna Gambarotta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1540453

3,487 views

13,029 articles

articles

Identification of hub genes associated with decreased fertility in male mice of advanced paternal age

Editorial: Methods to develop and study animal cell degeneration disorders resembling human pathologies

GSDME knockout alleviates hematopoietic stem cell irradiation injury and aggravates myeloid-biased differentiation

Editorial: New strategies for treating fusion-driven sarcomas

Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells

TAp73 modulates proliferation and ferroptosis in mammary epithelial cells

Heat shock affects the Ca2+/calmodulin-dependent protein kinase II dynamic during bovine sperm capacitation and acrosome reaction

lncRNA Ubr5 promotes BMSCs apoptosis and inhibits their proliferation and osteogenic differentiation in weightless bone loss

SIRT3/6/7: promising therapeutic targets for pulmonary fibrosis

Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities

Targeting tumor angiogenesis and metabolism with photodynamic nanomedicine

Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-β pathway in lung adenocarcinoma

Application of human cardiac organoids in cardiovascular disease research

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosis

Doxycycline inhibits MMP-2 retinal activity and modulates the angiogenic process in vitro and in vivo

Changes in the metabolome, lipidomein, and gut microbiota in Behçet’s disease

Arx revisited: involved in the development of GABAergic interneurons

Neuroimmunomodulation in chronic wounds: an opinion

Unveiling the impact of ERAP1 and ERAP2 on migration, angiogenesis and ER stress response

Increased amounts of cell-free DNA released from a culture with a high content of cancer stem cells

Lactylation in CNS disorders: mechanisms, cellular function, and disease relevance

KIF2C is essential for meiosis and manchette dynamics in male mice

Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms

Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury